CN106922722A - A kind of bactericidal composition - Google Patents

A kind of bactericidal composition Download PDF

Info

Publication number
CN106922722A
CN106922722A CN201511008815.5A CN201511008815A CN106922722A CN 106922722 A CN106922722 A CN 106922722A CN 201511008815 A CN201511008815 A CN 201511008815A CN 106922722 A CN106922722 A CN 106922722A
Authority
CN
China
Prior art keywords
plant
picarbutrazox
bactericidal composition
bellkute
bacterium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201511008815.5A
Other languages
Chinese (zh)
Inventor
罗昌炎
詹姆斯·T·布里斯托
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Rotam Chemical Co Ltd
Original Assignee
Jiangsu Rotam Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Rotam Chemical Co Ltd filed Critical Jiangsu Rotam Chemical Co Ltd
Priority to CN201511008815.5A priority Critical patent/CN106922722A/en
Publication of CN106922722A publication Critical patent/CN106922722A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01C—PLANTING; SOWING; FERTILISING
    • A01C1/00—Apparatus, or methods of use thereof, for testing or treating seed, roots, or the like, prior to sowing or planting
    • A01C1/08—Immunising seed
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
    • A01G13/00—Protecting plants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
    • A23B7/00—Preservation or chemical ripening of fruit or vegetables
    • A23B7/14—Preserving or ripening with chemicals not covered by groups A23B7/08 or A23B7/10
    • A23B7/153—Preserving or ripening with chemicals not covered by groups A23B7/08 or A23B7/10 in the form of liquids or solids
    • A23B7/154—Organic compounds; Microorganisms; Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical & Material Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Soil Sciences (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)

Abstract

The invention provides a kind of bactericidal composition, the microbicide compositions include active component Picarbutrazox and bellkute, and the weight ratio of Picarbutrazox and bellkute is 10:1-1:50.The present invention carries out binary built by by Picarbutrazox and bellkute so that the present invention has obvious gain effect on preventing and treating crop by fungi, bacterial disease；In addition fungicidal spectrum is also expanded by binary built, reduces respective usage amount, reduce the risk that germ develops immunity to drugs.

Description

A kind of bactericidal composition
Technical field
The present invention relates to a kind of bactericidal composition, plant, crop or seed are more particularly, to protected from fungal disease Bactericidal composition.
Background technology
The current disease control for being agriculturally also easy to produce resistance, mixture is carried out using the different pesticide species of the mechanism of action It is optimal selection, if reasonable mixture ratio, significant synergistic effect can be produced, field control effect is substantially better than each list The effect of agent.Bactericide containing single-activity composition is usually present certain defect, continuous several times in agricultural disease preventing and treating Using not only making pathogen be also easy to produce the resistance to the action of a drug, and easily cause the pollution to food and environment, by fungicidal activity into point it Between rational mixture can overcome disadvantage mentioned above.Rational compounding makes the synergistic effect that active ingredient is produced, and can improve preventive effect, subtracts Few effective ingredient consumption, it is cost-effective, delay the drug-fast generation of pathogen, and then can mitigate or even avoid agricultural chemicals to food The pollution of thing and environment.
On pesticide activity, particularly to crop protection, one of key problem of research carried out in the technical field is Improve the performance in terms of performance, especially bioactivity and the performance for keeping within a certain period of time in terms of this activity.
Picarbutrazox, test code number NF-171；CAS：500207-04-5；Chemical formula is [6- [[[[(z)-(1- first Base -1H-TETRAZOLE -5- bases)（Phenyl）Methylene] amino] epoxide] methyl] pyridine -2- bases] t-butyl carbamate；Molecular structure Formula is：
Picarbutrazox is the oximino ether bactericide of Japanese Cao Da companies exploitation, and it has preferable to downy mildew and epidemic disease Prevention effect.Picarbutrazox is by known in CN02817805.X.
Bellkute（Bellkute）, also known as the octyl benzene sulfonate of biguanides three, its chemical name is：1 ＇ 1- imino groups（It is pungent Methylene）Biguanides 3（Alkyl benzene sulfonate）, it is the antistaling disinfectant of the single molecular structure of biguanides salt, its structural formula is：
N=10~13
Bellkute is produced by Japanese Cao Da companies.Bellkute is tagged and prevention type bactericide as broad spectrum activity, local permeability By force, there is GIA very high to some disease funguses, its biosynthesis and cell mainly to Mycophyta ester compounds Film function works, and suppresses spore germination, germ tube elongation, the formation of appresorium and mycelia, can prevent and treat by most of sac fungus and The fungal disease that Fungi Imperfecti causes.Bellkute can be widely used for preventing and treating the fungal disease that most of sac fungus and Fungi Imperfecti cause, Particularly the gray mold of water fruits and vegetables and multiple kinds of crops, powdery mildew, sclerotiniose, stem wilt, blight dis-ease, anthracnose, wheel line The diseases such as disease, scab, leaf spot, spot defoliation, penicilliosis, green mould and fruit soft rot.Especially to tomato, light grey and pinkish Mildew, apple peels and cores, powdery mildew of cucumber, watermelon grafting have good preventive effect.
Because the environmental requirement and economic requirement now to bactericide are constantly improve, such as to activity profile, toxicity, selection The requirement of property, rate of application, residual and favourable preparation feasibility, additionally asks due to being there may be in terms of such as drug resistance Topic, therefore, exploitation is in some aspects lasting task better than the new bactericide of existing bactericide.
The content of the invention
It is an object of the invention to provide a kind of bactericidal composition, just reduced in the case where the reactive compound for reducing is using total amount and applied For activity profile with rate and improvement known compound Picarbutrazox and bellkute, the present invention is reducing reactive compound Under using total amount, having to harmful fungoid improves activity（Synergistic）.
We have found that simultaneously, i.e., jointly or separately applying Picarbutrazox and bellkute, or apply successively Picarbutrazox and bellkute cause preferably to prevent and treat harmful fungoid than each compound is administered alone.
The invention provides a kind of bactericidal composition, said composition carries out two by by Picarbutrazox and bellkute Unit's compounding so that the mixture for obtaining has gain effect in prevention effect, and has expanded fungicidal spectrum, serves a medicine many Effect, effectively slows down or avoids germ to develop immunity to drugs.Astoundingly, the bactericidal activity of bactericidal composition of the invention It is more active plus and considerably higher than each reactive compound.In other words, there is unpredictable, necessary being collaboration effect Should, and it is not only the supplement of activity.
When reactive compound is present in bactericidal composition of the invention with specific weight ratio, cooperative effect is especially bright It is aobvious.But, the weight ratio of the reactive compound in bactericidal composition of the present invention can change within the specific limits.
Can have greater activity and the more long bactericidal composition of activity holding the invention provides a kind of.This sterilized group Compound has relatively low-dose, while the toxicity of the bactericidal composition is relatively low, fruits and vegetables and seed with fungal disease is carried out Control.
A kind of bactericidal composition of the present invention is to take following technical scheme to realize：
A kind of bactericidal composition, it is characterised in that：Containing active component Picarbutrazox and bellkute, wherein The percentage by weight of Picarbutrazox and bellkute is 10:1-1:50, preferably 10:1-1:40, more preferably 10: 1-1:30, it is further preferably 1:1-1:25, it is further preferably 1:1-1:20, more preferably 1:1-1:15, more preferably 1:1-1:10.
The weight proportion of Picarbutrazox and bellkute in the present invention for example can also be 10:1、5:1、1:1、1: 5、1:10、1:15、1:20、1:25、1:30、1:35、1:40、1:45、1:50。
The Picarbutrazox and bellkute quality sum account for the 5%-90% of the Bactericidal composite amount of substance, more preferably 10%-80%, more preferably 20%-60%.
Described bactericidal composition, also comprising filler and/or surfactant.
A kind of method for preventing and treating plant pathogen, pathogenic bacteria and/or its environment, Huo Zhezhi are acted on by bactericidal composition In thing, plant parts, seed, soil, region, material or space.
It is a kind of prevent and treat plant pathogen method, by Picarbutrazox and bellkute be administered simultaneously or apply respectively, Or sequential application.
A kind of bactericidal composition, comprising Picarbutrazox and bellkute and filler and/or surfactant.
A kind of bactericidal composition, can be configured to any formulation for agriculturally allowing.The formulation of described bactericidal composition is It is suspending agent, seed coat agent, wettable powder, water dispersible granules, microcapsule suspending agent, coated granule, extrusion granule, missible oil, micro- Emulsion, aqueous emulsion, effervescent tablet, ultra low volume liquids.
Described bactericidal composition is used to prevent and treat cereal, vegetables, clover, soybean, turf, timber, trees, fruit tree or gardening The purposes of fungi and bacterium on plant.
The bactericidal composition is used to protect the purposes of plant propagation material and the plant organ for then growing.
The bactericidal composition is used to prevent and treat the purposes of fruit vegetables storing period disease.
The bactericidal composition be applied to needed for preventing and treating place preventing and treating soil cause a disease or saprophytic fungi and bacterium use On the way.
Described bactericidal composition is in various crop plants such as banana, cotton, vegetable variety（Such as cucumber, beans, tomato And cucurbitaceous plant）, it is barley, dogstail, oat, coffee, potato, corn, fruit variety, rice, rye, soybean, grapevine, small A large amount of fungies are prevented and treated in wheat, ornamental plant, sugarcane and a large amount of seeds to be even more important.
A kind of plant pathogenic fungi of control plant, plant part, plant propagation material and the plant organ for then growing Method, including by the amount of application of bactericidal composition of the invention effective and basic plant-less toxicity with agronomy with Seed Treatment, The methods such as foliage applying, stem are applied, are impregnated with, instiling, pouring into a mould, spraying, spraying, dusting, distribution or smoke are administered to plant, plant Partly, during plant propagation material or plant are growing or are needing the soil that grows wherein or cultivation medium.
Bactericidal composition of the invention has very strong activity to various phytopathogens, and can be to being drawn by phytopathogen The prevention and treatment of the plant disease for rising play very strong preventive effect.Bactericidal composition of the invention to such as Plasmodiophoromycetes, Oomycete, Chytridiomycetes, connect there is pole with the wide scope plant pathogenic fungi such as Gammaproteobacteria, Ascomycetes, Basidiomycetes, deuteromycetes Good activity.
Bactericidal composition of the invention also has extraordinary bactericidal performance, and it is thin to can be used for preventing and treating plant pathogenic Bacterium.Such as pseudomonadaceae, Rhizobiaceae, enterobacteriaceae, bar Cordycepps and Streptomycetaceae.
Bactericidal composition of the invention can be used as blade face fungicide in crop protection, can act also as fungicide use In seed dressing and as soil fungicide.
Bactericidal composite of the invention also can be used to prevent and treat the disease of fruit vegetables storing period.
Bactericidal composition of the invention is particularly suitable for the following phytopathogen of preventing and treating：
As oomycetes subclass, can be exemplified as, such as various crops such as the corruption of black leg of beet bacterium (Pythium ultium) Mould category bacterium；Such as potato blight bacterium (PhytophthoraiNfestaNs), botrytis cinerea (Phytophthora Capsici Phytophthora category bacterium)；Such as bacterium of downy mildew of cucumber (PseudoperoNospora cubeNsis), Humulus The Pseudoperonospora bacterium of Pseudoperonospora cubensis (PseudoperoNospora humuli)；Such as Plasmopara viticola (Plasmopara Viticola Plasmopara bacterium)；Such as Pseudoperonospora cubensis (PeroNospora brassicae), the green onion downy mildew of brassicaceous vegetable Germ (PeroNospora destructor), Peronospora bacterium of downy mildew of spinach bacterium (PeroNospora spiNaciae) etc..
As Ascomycetes, can be exemplified as, for example, such as the powdery mildew of powdery mildew of cereals bacterium (ErysiphegramiNis) Category bacterium；Such as the Sphaerotheca bacterium of greengrocery powdery mildew (Sphaerotheca fuligiNea)；Such as apple black star bacteria The Venturia bacterium of (VeNturia iNaequalis), pear cucumerinum (VeNturia Nashicola)；Such as net blotch of barley The PyreNophora category bacterium of bacterium (PyreNophorateres)；Such as wheat class spot disease (Cochliobolus sativus) Cochliobolus belongs to bacterium；Such as Sclerotinia bacterium of greengrocery hyphal cluster germ (SclerotiNia sclerotiorum).
As Basidiomycetes, can be exemplified as, for example, such as double spores of wheat leaf rust germ (PucciNiarecoNdita) Rust bacterium；Such as the Tilletia bacterium of bunt of wheat bacterium (Tilletia caries)；Such as loose smut of barley bacterium The Ustilago bacterium of (Ustilago Nuda) etc.
As Deuteromycotina, can be exemplified as, for example, such as the Phoma of lucid asparagus Phoma asparagi Sacc (Phomaasparagi) Bacterium；Such as the Septoria bacterium of wheat class crust rot bacterium (Septoria Nodorum)；Such as Colletotrichumlagenarium The Colletotrichum bacterium of (Colletotrichum lageNarium)；Such as wilt (Pyricularia oryzae) Pyricularia belongs to bacterium；Such as the Botrytis bacterium of greengrocery ash arrhizus bacteria (Botrytis ciNerea)；Such as apple spot fallen leaves Germ (AlterNaria mali), the Alternaria bacterium of tomato early blight bacterium (AlterNaria solaNi)；Such as beet Cercospora The Cercospora bacterium of germ (Cercospora beticola)；Such as peach black star germ (Cladosporium carpophilum) Blastocladia bacterium；Such as Rhizoctonia bacterium of Oryza sheath blight fungus (RhizoctoNia solaNi).
Suitable crop mainly includes field crop, such as corn, soybean, cotton, rape oilseeds, such as southern general rape (Brassica napus) (such as rape (canola)), overgrown with weeds green grass or young crops (Brassica rapa), leaf mustard (B.juncea) (such as mustard Sub (mustard)) and brassicacarinata (Brassica carinata), rice, wheat, beet, sugarcane, oat, brown wheat, greatly Wheat, broomcorn millet, triticale, flax, grapevine and the other fruit of various plants or vegetable crop, such as rose family (Rosaceaesp.) (for example, pip fruit, such as apple and pears, also drupe, such as apricot, cherry, almond and peach, berry such as strawberry), tea sugarcane Scarabaeidae (Ribesioidae sp.), Juglandaceae (Juglandaceae sp.), Betulaceae (Betulaceae sp.), Anacardiaceae (Anacardiaceae sp.), Fagaceae (Fagaceae sp.), Moraceae (Moraceae sp.), Oleaceae (Oleaceae Sp.), Actinidiaceae (Actinidaceae sp.), Lauraceae (Lauraceae sp.), Musaceae (Musaceae sp.) be (for example Banana tree and powder bajiao banana (plantings)), Rubiaceae (Rubiaceae sp.) (such as coffee), Theaceae (Theaceae Sp.), Sterculiaceae (Sterculiceaesp.), Rutaceae (Rutaceae sp.) (such as lemon, orange and grape fruit)；Solanaceae (Solanaceaesp.) (for example, tomato, potato, pepper, eggplant), Liliaceae (Liliaceae sp.), composite family (Compositiae sp.) (such as lettuce, globe artichoke and witloof-include root witloof (root chicory), hare's-lettuce (endive) Or common witloof (common chicory)), Umbelliferae (Umbelliferae sp.) (such as carrot, parsley, celery and block Rooted celery), Curcurbitaceae (Cucurbitaceae sp.) (for example cucumber-include pickled cucumber (pickling cucumber), south Melon, watermelon, cucurbit and muskmelon), green onion section (Alliaceae sp.) (such as onion and leek), Cruciferae (Cruciferae Sp.) (for example white cabbage, red cabbage, broccoli, cauliflower, brussels sprout, green vegetables, kohlrabi, radish, horseradish, solely Row dish, Chinese cabbage), pulse family (Leguminosaesp.) (such as peanut, pea and French beans-such as climning bean and broad bean), Chenopodiaceae (Chenopodiaceae sp.) (such as fodder beet, spinach sweet (spinach beet), spinach, beet root), Malvaceae (Malvaceae) (such as gumbo), Asparagaceae (Asparagaceae) (such as lucid asparagus)；Garden crop and forest crop； Ornamental plant；And the homologue of the genetic modification of these crops.
Bactericidal composition of the invention can be good preventing and treating cause pathogen and the medicament drug-fast bacteria of following disease：Tomato Phytophthora root rot, gray mold, leaf rust, spot disease, anthracnose and early phytophthora root rot；The downy mildew of cucumber, powdery mildew, gray mold, charcoal Subcutaneous ulcer is sick, withered rattan disease, black spot and brown spot；The anthracnose and gray mold of strawberry；The powdery mildew of pumpkin, anthracnose and withered rattan disease； The hickie leaf blight of onion, black spot, gray mold and Mild Powder；The powdery mildew of eggplant, gray mold and bacterial blight；The blackspot of shallot Disease；The Leucoplakia and black spot of Chinese cabbage；The sclerotiniose and gray mold of green pepper；The powdery mildew of cucumber, anthracnose and withered rattan disease；It is sweet The powdery mildew of melon, anthracnose and withered rattan disease；The gray mold of lettuce；The black spot and gray mold of red bayberry；The powdery mildew of persimmon, anthrax Disease, gray mold and defoliation；The gray mold of oranges and tangerines；The scab of pears, black spot and early phytophthora root rot；The gray mold of grape, anthrax Disease, brown spot, black rattan are sick, withered rattan is sick, viscous rot and the swollen disease of branch；The scab of peach, graywall, anthracnose；The black star of apple Disease, zonate spot, early phytophthora root rot, brown spot, coal point disease, coal spot disease, diplostomiasis and brown rot；The stem wilt of mung bean, anthracnose, ash Mildew and sclerotiniose；The anthracnose of Kidney bean, gray mold and sclerotiniose；The ring spot of broad bean；Purple spot of soybean；The white powder of tobacco Disease, the brown spot and spot disease of beet；The anthracnose of tea, zonate spot and the withered disease of sprouting and gray mold；Scab, the charcoal of flower class The plant diseases such as subcutaneous ulcer disease, gray mold and powdery mildew.Preventing and treating tomato, cucumber, eggplant, strawberry, grape, peach that particularly can be good Son and the epidemic disease of oranges and tangerines, the phytopathogen of powdery mildew and the gray mold cause of disease and medicament drug-fast bacteria.
Bactericidal composition of the invention is especially suitable for preventing and treating apple, banana, grape, oranges and tangerines, mango, paddy rice, wheat, jade Downy mildew on rice, potato, soybean, tomato, capsicum, cucumber, eggplant, grape, early blight, late blight, balck shank, scab, Leaf spot, anthracnose, powdery mildew, wilt disease.
The crop of bactericidal composition treatment of the invention is such as but not limited to cereal, vegetables, clover, soybean, turf, wood Material, trees, fruit tree or gardening plant.
Fungicidai mixtures of the invention can also be used to prevent and treat fruit vegetables storing period disease.The fruit for for example being caused by following pathogen It is real to rot：
Aspergillus bacterium, such as aspergillus flavus；
Botrytis（Botrytis）Strain, such as Botrytis cinerea（Botrytis cinerea）;
Penicillium（Penicillium）Strain, such as penicillium expansum（Penicillium expansum）With P.purpurogenum;
Sclerotinia（Sclerotinia）Strain, such as sclerotinite（ Sclerotinia sclerotiorum）;
Verticillium（Verticilium）Strain, such as black and white wheel branch spore（Verticilium alboatrum）.
Bactericidal composition of the invention be also particularly well suited for preventing and treating fruit vegetables storing period disease blossom-end rot, green mould, penicilliosis, Anthracnose.
Fungicidai mixtures of the invention can be additionally used in preventing and treating kind and pass and soil-borne disease.The kind for for example being caused by following pathogen Pass and native rotten and wilting disease and the seedling disease for passing：
Alternaria category kind, such as rape give birth to rod method (Alternaria brassicicola);
Aphanomyces (Aphanomyce) category kind, such as mould (Aphanomyces of Kidney bean silk capsule
euteiches) ;
Ascochyta (Ascochyta) category kind, such as Ascochyta lentis;
Aspergillus, such as aspergillus flavus;
Cladosporium category kind, such as draft branch spore (Cladosporium herbarum);
Cochliobolus category category kind, such as standing grain cochliobolus;
(conidial form:Drechslera, Syn:The compacted spore bacterium of length);
Colletotrichum category kind, such as hair core anthrax-bacilus (Colletotrichum coccodes);
Fusarium category kind, such as yellow fusarium;
Gibberella category kind, such as beautiful another name for Sichuan Province multitude is red mould;
Shell ball spore category (Macrophomina) category kind, such as Kidney bean shell ball spore (Macrophomina
phaseolina) ;
Small setting-out shell belongs to strain, for example, avenge rotten small setting-out shell;
Penicillium category kind, such as penicillium expansum;
Phaeosphaeria strains, such as Phaeosphaeria nodorum;
Phoma (Phoma) category kind, such as black embryo Phoma sp (Phoma lingam);
Phomopsis (Phomopsis), such as soybean Phomopsis (Phomopsis sojae);
Phytophthora category kind, such as Phytophthora cactorum (Phytophthora cactorum);
Nuclear cavity Pseudomonas category kind, such as wheat class nuclear cavity bacteria (Pyrenophora graminea);
Pyricularia Sacc. (Pyricularia) category kind, such as Magnaporthe grisea (Pyricularia oryzae);
Pythium kind, such as Pythium ultimum;
Rhizoctonia category kind, such as Rhizoctonia solani Kuhn;
Rhizopus (Rhizopus) category kind, such as Rhizopus oryzae (Rhizopus oryzae);
Bulbil category (Sclerotium) category kind, such as Sclerotium rolfsii (Sclerotium rolfsii);
Core coral Pseudomonas (Typhula) category kind, such as meat spore core coral bacterium (Typhula incarnata);
Verticillium (Verticillium) category kind, such as verticillium dahliae (Verticillium dahliae).
The present invention provides the plant of a kind of control plant, plant part, plant propagation material and the plant organ for then growing The method of thing disease fungus, including by the amount of application of bactericidal composition of the invention effective and basic plant-less toxicity with agronomy with The methods such as Seed Treatment, foliage applying, stem are applied, are impregnated with, instiling, pouring into a mould, spraying, spraying, dusting, distribution or smoke are administered to Plant, plant part, plant propagation material or plant are being grown or needed in the soil or cultivation medium for growing wherein.
The present invention provides a kind of method for preventing and treating plant pathogen, and bactericidal composition is acted on into pathogenic bacteria and/or its ring In border, or plant, plant parts, plant propagation material, soil, region, material or space.
Bactericidal composition of the invention can be used for the plant device protected plant part, plant propagation material and then grow Official.
Bactericidal composition of the invention, can process all plants and plant part." plant " refers to all plants and plant Population, such as preferably with undesirable wild plant, cultivated plant and plant variety (regardless of whether receiving plant variety or plant Cultivate the protection of people's right).Cultivated plant and plant variety can be the plants obtained by Sterile culture and breeding method, this A little methods can be aided with or be supplemented with one or more biological technique method, such as using dihaploid, protoplast fusion, random With orthomutation, molecule or genetic marker, or use bioengineering and genetic engineering method.Plant part refers to all of plant Above and below the ground part and organ, such as bud, leaf, Hua Hegen, such as leaf, needle, stem, branch, flower, fructification, fruit and kind Son and root, bulb and rhizome.Crop and nourish and generate and case of propagation material, for example, transplant, bulb, rhizome, running roots Plant part is fallen within seed.
Term " plant propagation material " is interpreted as referring to all plant parts for having a fertility, such as seed, and it can be used In breeding the latter, and vegetable matter such as cuttage bar or stem tuber（Such as potato）.Therefore, plant used herein Part includes plant propagation material.It is mentioned that such as seed, root, fruit, stem tuber, bulb, rhizome and plant part.Treat The germination plant and effective plant suppressed after being germinateed from soil or after emerging.Young plant can before transplantation by being impregnated into Row whole or Local treatment are protected.
Currently preferred propagating materials is seed.The method of Seed Treatment, for example, can there are, diluent liquid or solid The medicament of shape or seed is directly immersed in liquid condition solution the method for making medicament be impregnated with seed without dilution, by solid Medicament or liquid preparation are mixed with seed, be coated treatment make the surface of the seed adhere to medicament method, plantation Simultaneously near seed sprinkling etc. method.
Plant part and the plant organ for then growing are by any of the plant propagation material such as plant of seed generation Part.Plant part, plant organ and plant can also be benefited from and be applied to plant propagation material institute by by bactericidal composition The pathogenic damage protection of acquisition.The plant organ grown behind certain plants part and some places can also regard plant propagation as Material, its own can be applied with bactericidal composition（Or treatment）；So as to by the plant part through processing and the plant through processing Plant, other plant parts and the other plant organs that organ is produced can also be benefited from and applied by by bactericidal composition With.
Bactericidal composition of the invention can also be used to prevent or control soil or cultivate various in medium causing a disease or saprophytic Fungi and bacterium.The example of the aquacultural fungal pathogen of soil-borne includes Alternaria（Alternaria spp.）, Ascochyta (Ascochyta spp.), Botrytis cinerea（Botrytis cinerea, Cercospora（Cercospora spp., ergot （Claviceps purpurea）, standing grain cochliobolus（Cochliobolus sativus）, Colletotrichum （Colletotrichum spp., Epicoccum（Epicoccum spp., F.graminearum schw（Fusarium graminearum）, Rice dislikes seedling chain spore（Fusarium moniliforme）, fusarium oxysporum（Fusarium oxysporum, fusarium moniliforme （Fusarium proliferatum）, fusariun solani (Fusarium solani), dimension glue chain spore (Fusarium Subglitinans), Helminthosporium (Helminthosporium spp), rotten microtorr bacterium (Microdochium nivale) of snow, Penicillium (Pencillium spp), Phoma (Phoma spp.), wheat class nuclear cavity bacteria (Pyrenophora graminea), Rice blast Pyricularia Sacc. (Pyricularia oryzae), Rhizoctonia solani Kuhn (Rhizoctonia solani), Rhizoctonia cerealis (Rhizoctonia cerealis), Sclerotinia (Sclerotinia spp.), Septoria (Septoria spp.), silk Axle smut (Sphacelotheca reilliana), Tilletia (Tilletia spp.), meat spore core coral bacterium (Typhula incarnate), hidden bar smut (Urocystis occulta), Ustilago (Ustilago spp.) or wheel Cladosporium (Verticillium spp.).
Soil germ has rhizoctonia solani, sickle-like bacteria, phytophthora, bacterium of dampinging off, root rot, pythium spp, botrytis cinerea, soft-rot fungi Deng.In general, soil germ can produce a large amount of thalline, as long as condition is favourable to pathogen growth development, host is sense Disease, germ just with amount reproduction and can infect host, and in the presence of susceptible host, these germs can just enter lasting The phase of causing a disease, the amount reproduction diffusion with the continuous cropping of crop, but nutrient is depleted or edaphic condition such as temperature, humidity etc. afterwards When unfavorable to germ, germ can enter rest period again.When susceptible host does not exist, soil-borne disease bacterium can also survive in soil Get off, in addition to soil germ has extensive host range, moreover it is possible to survived on the root surface of non-host or the broken branches and fallen leaves, with it It is undivided with saprophytic competitiveness.But different germs are discrepant, as sickle-like bacteria almost can be unlimited in soil Phase survives.
Cultivation medium of the present invention is the supporter for referring to make crops take root, grow, for example：Soil, water etc., Specific raw material can using such as sand, float stone, vermiculite, diatomite, agar-agar, gelling material, polymer substance, asbestos, Wood chip, bark etc..
To the method in soil using medicament, for example, liquid preparation is diluted in water or do not diluted and be directly applied to plant The medium method in the root of body or the rice seedling bed of seedling, the side in the rice seedling bed of the root of plant or seedling is disseminated to by granule Method has the method that pulvis, water dispersible granules etc. are sprayed in soil and are integrally mixed with soil prior to seeding, and sowing is preceding or plants In being sprayed on implantation hole, seed furrow after pulvis, water-dispersible grain dilution agent before kind plant, in method sowed etc..
Another object of the present invention, there is provided a kind of control plant, plant part, plant propagation material and then grow The method of the plant pathogenic fungi of plant organ, the method include by bactericidal composition of the invention with agronomy it is effective and substantially without Phytotoxic amount of application is applied with Seed Treatment, foliage applying, stem, is impregnated with, instiled, poured into a mould, sprayed, sprayed, dusting, distribution Or the method such as smoke is administered to plant, plant part, plant propagation material or plant and is growing or needing what is grown wherein In soil or cultivation medium.
Bactericidal composition of the invention can be applied by different processing methods, and these methods are for example：
- liquid comprising the bactericidal composition is sprayed onto the aerial part of the plant；
- dusting, mixes particle or powder in soil, in surrounding plants sprinkling, and in tree injection or the situation of smearing Under；
- seed of plant is coated or film coated.
- for postharvest fruit and vegetable anti-corrosive fresh-keeping when, 200-2000 times of liquid of usual dilute with water, leaching fruit after leach.
The present invention provides a kind of method for preventing and treating plant pathogen, can treat, prevent or method of eradication.
Bactericidal composition of the invention can be made into common dosage form, such as missible oil, wettable powder, suspending agent, liquid The dosage forms such as agent, granule, seed coat agent are used, its amount of application, mixing ratio, meteorological condition according to active ingredient, medicament Form, Dressing date, application process, using place, prevent and kill off the different and variant of object noxious livings, objective crop etc..
It is a kind of prevent and treat plant pathogen method, by Picarbutrazox and bellkute be administered simultaneously or apply respectively, Or sequential application.
Treatment in accordance with the present invention is there may be super plus (" collaboration ") effect.For example, sterilized group used according to the present invention The rate of application of compound and/or widen its field of activity and/or increase its activity, it is possible to obtain following effect：More preferable plant Growth, the tolerance to high temperature or low temperature increases, and the tolerance to arid or water or soil salt content increases, and performance of blooming is carried It is high, it is easier to harvest, the maturation of quickening, yield rate higher, bigger fruit, plant height higher, the color of leaf is more It is green, to bloom earlier, the quality or nutritive value of the product of results are higher, and sugared concentration is higher in fruit, the storage of the product of results More preferably, these benefits have exceeded the effect actually estimated for stability and/or processability.
Processing method of the invention can be additionally used in process propagating materials such as stem tuber or rhizome, and can be used for treatment seed, Seedling or transplanting (pricking out) seedling and plant or transplanting plant.The processing method can also be used for processing root.The present invention Processing method can also be used for processing the aerial part of plant such as about the doing of plant, stem or stalk, leaf, flower and fruit.
- generally for leaf portion treatment：0.1-10000g/ha, preferably 10-1000 g/ha, more preferably 50-500 g/ha；It is right For dipping or administration of instiling, the dosage can also even be reduced, particularly when using inert base such as asbestos or pearl During rock；
- for Seed Treatment：2-5000g/100kg seeds, preferably 3-1000g/100kg seeds；
- for soil or treatment used for ponds：0.1-10000g/ha, preferably 1-1000g/ha.
Above-mentioned dosage is only general exemplary dose, and those skilled in the art can be according to actual feelings during actual administration Condition and needs, the seriousness especially in accordance with the property and germ of pending plant or crop adjust rate of application.
Picarbutrazox of the invention is combined with bellkute/co-administered.Including separating, sequentially or simultaneously applying Picarbutrazox and bellkute.Preferably, the Picarbutrazox is combined as comprising Picarbutrazox with bellkute With the form of the composition of bellkute.
Composition of the invention can be based on dosage form, i.e., each material is blended in composition, composition into Point can also unit dose form provide, use it is preceding mix in bucket or tank, be then diluted to required concentration.Wherein preferably with this hair Based on the dosage form of bright offer.
As a further improvement on the present invention, bactericidal composition of the invention can be configured to any agent for agriculturally allowing Type.
As a further improvement on the present invention, the formulation of bactericidal composition of the invention is suspending agent, seed coat agent, wettable It is pulvis, water dispersible granules, microcapsule suspending agent, coated granule, extrusion granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet, super Low capacity liquor.
In bactericidal composition of the present invention, lived comprising Picarbutrazox and bellkute, filler and/or surface Property agent.
The content of bactericidal composition of the present invention, wherein Picarbutrazox and bellkute accounts for bactericidal composition 5%-90%。
The content of described bactericidal composition, wherein Picarbutrazox and bellkute accounts for the 10%- of bactericidal composition 80%。
The content of described bactericidal composition, wherein Picarbutrazox and bellkute accounts for the 20%- of bactericidal composition 60%。
According to the present invention, term " filler " refers to can be combined with reactive compound or combines to make it easier for being administered to Object（Such as plant, crop or careless class）Natural or synthetic organic or inorganic compound.Therefore, the filler is preferably It is inert, at least should be agricultural acceptable.The filler can be solid or liquid.
The nonactive medium that can be used in the present invention both can be that solid can also be liquid, can be as solid matchmaker What dielectric material was used has for example：Phyteral powdery type（Such as soy meal, starch, grain dust, wood powder, bark powder, sawdust, walnut The particle of shell powder, wheat bran, cellulose powder, coconut husk, corncob and tobacco stem, extracts residue after plant essence etc.）, paper , sawdust, crush synthesized polymer body, the clay class of synthetic resin etc.（Such as kaolin, bentonite, acid china clay etc.）, talcum powder Class.Silica（Such as diatomite, silica sand, mica, aqueous silicic acid, calcium silicates）, activated carbon, natural mineral matter class（Float stone, Lv Po Thread stone and zeolite etc.）, fire diatomite, sand, plastics medium etc.（Such as polyethylene, polypropylene, polyvinylidene chloride etc.）, chlorination The chemical fertilizer of inorganic mineral powder, ammonium sulfate, ammonium phosphate, urea, the ammonium chloride of potassium, calcium carbonate, calcium phosphate etc. etc., soil Fertilizer, these materials can be used alone or two or more is mixed.
Can be selected in llowing group of materials as liquid media materials'use, such as water, alcohol type（Such as first Alcohol, ethanol, isopropanol, butanol, ethylene glycol etc.）, ketone（Such as acetone, methyl ethyl ketone, isobutyrone, cyclohexanone Deng）, ethers（Such as ether, dioxanes, methylcellulose, tetrahydrofuran etc.）, aliphatic hydrocarbon class（Such as kerosene, Mineral oil etc.）, aromatic hydrocarbons class（Such as benzene,toluene,xylene, solvent naphtha, alkylnaphthalene, chlorinated aromatic hydrocarbons, chloro fat Fat hydrocarbon, chlorobenzene, etc.）, halogenated hydrocarbon class, amide-type, sulfone class, dimethyl sulfoxide (DMSO), mineral and vegetable oil, animal oil etc..
To emulsify active ingredient compound, dispersion and/or soak, it is possible to use surfactant for example can be with Enumerate AEO, polyoxyethylene alkylaryl ether, polyoxyethylene higher fatty acid esters, polyoxyethylene alcohol or phenol Phosphate, the fatty acid ester of polyalcohol, alkane aromatic sulfonic acid, naphthalene sulfonic acid polymer, lignosulfonates, the branch shape of macromolecule comb shape are total to Polymers, butyl naphthalene sulfonate, alkylaryl sulfonates, sodium alkylsulfosuccinates, grease, fatty alcohol and ethylene oxide condensation The polyacrylates such as thing, alkyltaurate, protein hydrolysate.Suitable oligosaccharide thing or polymer, such as based on independent Vinyl monomer, acrylic acid, polyoxyethylene and/or polyoxypropylene or its with for example（It is polynary）Alcohol or（It is polynary）The combination of amine.
To make active ingredient compound dispersion stability, attachment and/or combining, such as xanthans, silicic acid can be used Magnalium, gelatin, starch, methyl cellulose, polyvinyl alcohol, polyvinyl acetate and natural phospholipid（Such as cephalin and lecithin）With And the adjuvant such as synthetic phospholipid, bentonite, sodium lignin sulfonate.
The wherein optional spent glycol of antifreezing agent, propane diols, glycerine, sorbierite.As the deflocculant of suspension product The adjuvant of such as naphthalene sulfonic acid polymer, polymeric phosphate etc. can be used.
Organic silicon defoamer can be used as defoamer.
The colouring agent that can be used, such as inorganic pigment, such as iron oxide, titanium oxide and Prussian blue；And organic pigment/ Dyestuff：Alizarin dyes, azo dyes and metallized phthalocyanine dye；And trace element, such as molysite, manganese salt, boron salt, mantoquita, cobalt Salt, molybdenum salt and zinc salt.
Optionally, can also include other annexing ingredients, for example protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent, Stabilizer, screening agent.
The reactive compound can be mixed and prepared by the preparation of the invention by known way with conventional additives. The conventional additives such as conventional extender and solvent or diluent, emulsifying agent, dispersant, and/or adhesive or fixative, Wetting agent, waterproofing agent, if it is desired, drier and colouring agent, stabilizer, pigment, defoamer, preservative, increasing can also be included Thick dose, water and other processing aids.
Bactericidal composition of the invention not only includes can be by suitable equipment as spraying or dusting equipment are applied to immediately Pending object, and the concentration commercial composition for needing to be diluted is additionally included in before being applied to object.
It is of the invention to be applied with other active ingredient combinations containing Picarbutrazox and bellkute, for example for Expand activity profile or prevent from forming resistance.Described other active components such as fungicide, bactericide, attractant, kill insect Agent, acaricide, nematicide, growth regulator, herbicide, safener, fertilizer or semiochemical etc..
Reactive compound Picarbutrazox and bellkute can be administered simultaneously, or apply respectively, or sequential application, separate Using when order on prevent and treat result generally without influence.
Composition of the invention can be based on dosage form, i.e., each material is blended in composition, composition into Point can also unit dose form provide, use it is preceding mix in bucket or tank, be then diluted to required concentration.Wherein preferably with this hair Based on the dosage form of bright offer.
The present invention has the advantages that compared with prior art：
The invention provides a kind of bactericidal composition, binary built is carried out by by Picarbutrazox and bellkute so that this Invention has obvious gain effect on preventing and treating crop by fungi, bacterial disease；In addition also expanded by binary built Big fungicidal spectrum, reduces respective usage amount, reduces the risk that germ develops immunity to drugs.
Specific embodiment
The invention will be further elaborated to first pass through specific example of formulations below.
Example of formulations
Embodiment 1：40% Picarbutrazox bellkute wettable powders
Picarbutrazox10%, bellkute 30%, lignosulfonates 6%, spaonin powder 4%, attapulgite adds to 100%, will Aforementioned formula material mixes, the uniform stirring in stirred tank, is remixed after airslide disintegrating mill uniformly, that is, be obtained 40% Picarbutrazox bellkute wettable powders.
Embodiment 2：50% Picarbutrazox bellkute wettable powders:
Picarbutrazox 5%, bellkute 45%, naphthalene sulfonic acid-formaldehyde condensation product 8%, tea seed cake 5%, kaolin adds to 100%, will be preceding Formulation material mixing is stated, the uniform stirring in stirred tank is being well mixed after airslide disintegrating mill, is obtained 50% Picarbutrazox bellkute wettable powders.
Embodiment 3：51% Picarbutrazox bellkute wettable powders
Picarbutrazox 1%, bellkute 50%, AEO 7%, wetting and penetrating agent F 5%, diatomite is added to 100%, aforementioned formula material is mixed, the uniform stirring in stirred tank, it is being well mixed after airslide disintegrating mill, it is obtained 51% Picarbutrazox bellkute wettable powders.
Embodiment 4：32% Picarbutrazox bellkute water dispersible granules
Picarbutrazox 2%, bellkute 30%, alkyl benzene sulfonate calcium salt 8%, Nekal BX 6%, ammonium sulfate 2%, bentonite adds To 100%, aforementioned formula material is uniformly mixed, with micro jet, through mediating, being subsequently adding fluidized-bed granulation dryer In granulated, dry, sieve after be mixed to prepare 32% Picarbutrazox bellkute water dispersible granules through sampling analysis.
Embodiment 5：60% Picarbutrazox bellkute water dispersible granules
Picarbutrazox20%, bellkute 40%, aliphatic acid polyethenoxy ether 7%, lauryl sodium sulfate 4%, aluminium chloride 2.8%, kaolin adds to 100%, and aforementioned formula material is uniformly mixed, with micro jet, through mediating, being subsequently adding fluidisation Bed granulating and drying machine in granulated, dry, sieve after be mixed to prepare 60% Picarbutrazox bellkutes through sampling analysis Water dispersible granules.
Embodiment 6：90% Picarbutrazox bellkute water dispersible granules
Picarbutrazox20%, bellkute 70%, octylphenol polyethylene oxyethylene group ether sulfate 1%, neopelex 1%, Sodium carbonate 1%, white carbon adds to 100%, and aforementioned formula material is uniformly mixed, with micro jet, through mediating, being subsequently adding Granulated in fluidized-bed granulation dryer, dried, sieve after through sampling analysis i.e. be obtained 90% Picarbutrazox hundred can Obtain water dispersible granules.
Embodiment 7：45% Picarbutrazox bellkute suspending agents
Picarbutrazox5%, bellkute 40%, polycarboxylate 6%, silicone oil 0.3%, xanthans 0.9%, diethylene glycol (DEG) 2.5%, go from Sub- water adds to 100%, remaining component after thickener and antifreezing agent are mixed in addition to active ingredient is crossed, and mixes by high speed shear Uniformly, active ingredient is added, ball milling 2 ~ 3 hours in ball mill make particle diameter all below 5 μm, that is, is obtained 45% Picarbutrazox bellkute suspending agents.
Embodiment 8：55% Picarbutrazox bellkute suspending agents
Picarbutrazox5%, bellkute 50%, naphthalene sulfonic acid-formaldehyde condensation product 6%, hydroxyethyl cellulose 0.7%, silicone chemical combination Thing 0.1%, polyethylene glycol 2%, deionized water adds to 100%, remaining group after thickener and antifreezing agent are mixed in addition to active ingredient Point, it is well mixed by high speed shear, add active ingredient, ball milling 2 ~ 3 hours in ball mill, make particle diameter all 5 μm with Under, that is, 55% Picarbutrazox bellkute suspending agents are obtained.
Embodiment 9：40% Picarbutrazox bellkute suspending agents
Picarbutrazox15%, bellkute 25%, lignosulfonates 8%, Magnesiumaluminumsilicate 1%, silicone 0.2%, glycerine 2.8%, deionized water adds to 100%, remaining component after thickener and antifreezing agent are mixed in addition to active ingredient, is cut by high speed Cut well mixed, add active ingredient, ball milling 2 ~ 3 hours in ball mill make particle diameter all below 5 μm, i.e., prepared 40% Picarbutrazox bellkute suspending agents.
Embodiment 10：5% Picarbutrazox bellkute suspension emulsions
Picarbutrazox 1%, bellkute 4%, alkyl benzene sulfonate calcium salt 7%, methylcellulose 1.2%, propane diols 2.4%, C8~10 Aliphatic alcohols 0.4%, Tween 80 7%, water adds to 100%；Finely ground hundred are added in the continuous phase containing Picarbutrazox Available suspended phase, is mixed to prepare 5% Picarbutrazox bellkute suspension emulsions.
Embodiment 11：20% Picarbutrazox bellkute suspension emulsions
Picarbutrazox 5%, bellkute 15%, lignosulfonates 6%, xanthans 0.8%, ethylene glycol 2.5%, SOLVESSOTM100 15%, silicone oil 0.2%, 600# phosphates 5%, water adds to 100%.In the continuous phase containing Picarbutrazox The suspended phase of the finely ground bellkute of middle addition, is mixed to prepare 20% Picarbutrazox bellkute suspension emulsions.
Embodiment 12：30% Picarbutrazox bellkute suspension emulsions
Picarbutrazox10%, bellkute 20%, naphthalene sulfonic acid-formaldehyde condensation product 7%, spaonin powder 3%, phenolic resin 1.1%, three is sweet Alcohol 2%, silicone 0.1%, agriculture breast 400#6%, water adds to 100%, is added in the continuous phase containing Picarbutrazox finely ground Bellkute suspended phase, be mixed to prepare 30% Picarbutrazox bellkute suspension emulsions.
Embodiment 13：10% Picarbutrazox bellkute microemulsions
Picarbutrazox2%, bellkute 8%, N- methyl pyrrolidones 6%, oxirane-propylene oxide block copolymer 4%th, alkyl biphenyl ether disulfonic acid magnesium salts 5%, silicone compound 0.4%, toluene 3%, propane diols 2%, epoxychloropropane 1.1%, go Ionized water adds to 100%, is made 10% Picarbutrazox bellkute microemulsions.
Embodiment 14：5% Picarbutrazox bellkute microemulsions
Picarbutrazox 1%, bellkute 4%, cyclohexanone 5%, agriculture breast 500#4%, Nongru-700 #5%, C8~10Aliphatic alcohols 0.2%th, ethyl acetate 2.5%, polyethylene glycol 2%, tributyl phosphate 1.4%, deionized water add to 100%, are made 5% Picarbutrazox bellkute microemulsions.
Embodiment 15：50% Picarbutrazox bellkute water dispersible granules
Picarbutrazox10%, bellkute 40%, octylphenol polyethylene oxyethylene group ether sulfate 1%, neopelex 1%, sodium carbonate 1%, white carbon adds to 100%, and aforementioned formula material is uniformly mixed, with micro jet, through mediating and then Add granulated in fluidized-bed granulation dryer, dry, sieve after through i.e. prepared 50% Picarbutrazox of sampling analysis Bellkute water dispersible granules.
Embodiment 16：10% Picarbutrazox bellkute aqueous emulsions
Picarbutrazox5%, bellkute 5%, 600# phosphates 4%, propyl alcohol 7%, agriculture breast 600#3%, xanthans 0.7%, propane diols 2.4%th, toluene 4%, deionized water adds to 100%, is made 10% Picarbutrazox bellkute aqueous emulsions.
Embodiment 17：6% Picarbutrazox bellkute missible oil
Picarbutrazox1%, bellkute 5%, ethoxylated castor oil 5%, calcium dodecyl benzene sulfonate 3%, SOLVESSOTM 200 add to 100%, stir to transparent homogeneous phase is obtained, and obtain 6% Picarbutrazox bellkute missible oil.
Embodiment 18：40%Picarbutrazox bellkute microcapsule suspension-suspendinagent agents
Picarbutrazox 10%, bellkute 30%, Synperonic PE/64 15%, citric acid 0.05%, water 10%, PAPI 20%, SOLVESSOTM100 5%, dispersant LFH0.15%, defoamer 0.16%, urea 5.5%；Water complements to 100%； By PAPI, Picarbutrazox, SOLVESSOTM100 oil phases for being formed are added in the aqueous solution containing Synperonic PE/64, Form emulsion.Then heat and be incubated and add catalyst reaction 2 hours at 50 DEG C.Picarbutrazox is obtained after cooling Microcapsules.Synperonic PE/64, dispersant LFH, defoamer, urea, bellkute and water are mixed in proportion, and are passed through It is sanded, is prepared into suspending agent.The Picarbutrazox microcapsules that will be obtained is added in the suspending agent of bellkute, is stirred To 40%Picarbutrazox bellkute microcapsule suspension-suspendinagent agents.
The 35%Picarbutrazox bellkute seed coat agents of embodiment 19
Picarbutrazox 5%, bellkute 30%, AEO sulfosuccinic acid monoesters disodium 10%, innovation wood Quality sulfoacid calcium 5%, xanthans 1%, bentonite 1%.Glycerine 5%,
PVP-K30 1%, complements to 100%, and above-mentioned each component is mixed in proportion, and through being sanded, is prepared into 35% Picarbutrazox bellkute seed coat agents.
The 50%Picarbutrazox bellkute coated granules of embodiment 20
Picarbutrazox 10%, bellkute 40%, polyethylene glycol 3%, the silicic acid 1% of high degree of dispersion,
Calcium carbonate complements to 100%, in a mixer, by levigate active component even spread to the load soaked by polyethylene glycol On body, the dust-free coated granules agent of 50%Picarbutrazox bellkutes can be obtained in this way.
Be well mixed for Picarbutrazox 30% and bellkute 70% by embodiment 21.
The just Picarbutrazox 20% of embodiment 22 and bellkute 80% are well mixed.
Above example proportioning is weight per distribution ratio.
Biological test example：
The combination of active principles of different agricultural chemicals is made agricultural chemicals, is exploitation at present and development novel pesticide and preventing and treating agriculturally resistance A kind of effective and quick way of germ.After the pestsides synthesis of different cultivars, three kinds of type of action are typically exhibited：It is added and makees With, synergistic effect and antagonism.But which kind of effect be specially, it is impossible to predict, only just be can know that by many experiments.Compounding Synergy is formulated well, due to significantly improving actual prevention effect, reduces the usage amount of agricultural chemicals, so as to greatly delay The generation of resistance.
First, virulence test：
The toxicity index of each medicament and the co-toxicity coefficient of mixture are calculated according to the abundant methods of Sun Yun（CTC values）, when CTC≤80, then combine Thing shows antagonism, when 80<CTC<120, then composition show summation action, when CTC >=120, then composition performance Go out synergistic effect.
Actual measurement toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) * 100
B in the percentage composition+B medicament toxicity index * mixtures of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixtures Percentage composition
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixture theoretical toxicity index (TTI) * 100
Experiment 1：The toxicity test of cucumber downy mildew
Selected from the cucumber seedling that growing way is consistent, sprayed under 50PSI pressure with potter spray towers, per basin about 5mL, each medicine Agent sets 12 concentration gradients.24h connects bacterium after chemicals treatment, and the cucumber downy mildew leaf that will pick up from field is uniform above cucumber seedling Shake off conidium to be inoculated with, then cucumber seedling is put into greenhouse and is cultivated.Morbidity after 7d according to cucumber downy mildew is classified Standard complete stool investigates disease index, and calculates prevention effect, and concentration EC50 in suppressing then is calculated with least square method, then according to grandson Yun Peifa calculates co-toxicity coefficient (CTC).
Table 1
As known from Table 1, Picarbutrazox and bellkute are preventing the weight proportion 10 of cucumber downy mildew:1-1:50 scope In when, co-toxicity coefficient is all higher than 120, illustrates that both show as gain effect at mixture in the range of this.
Experiment 2：The toxicity test of tomato blight
Selected from the tomato seedling that growing way is consistent, each treatment supplies examination leaf seedling from 3 basins, with potter spray towers under 50PSI pressure Spraying, per basin about 5mL, each medicament sets 12 concentration gradients.24h connects bacterium after chemicals treatment, will pick up from the tomato in field Epidemic disease leaf is uniformly shaken off conidium above tomato seedling and is inoculated with, and then tomato seedling is put into greenhouse and is cultivated.Pressed after 7d Morbidity grade scale complete stool according to tomato blight investigates disease index, and calculates prevention effect, is then calculated with least square method Concentration EC50 in suppression, then calculate co-toxicity coefficient (CTC) according to the abundant methods of Sun Yun.
Table 2：Virulence test result of the present invention on preventing and treating tomato blight
As known from Table 2, Picarbutrazox and bellkute are preventing the weight proportion 10 of tomato blight:1-1:In 50 scope When, co-toxicity coefficient is all higher than 120, illustrates that both mixtures in the range of this show as gain effect.
Experiment 3：The toxicity test of Penicillium italicum
Using suppression mycelial growth rate method：Experiment target is designated as Penicillium italicum.
By Picarbutrazox and bellkute respectively use acetone solution, then with 0.1% the Tween-80 aqueous solution dilute match somebody with somebody The liquid of series concentration is made, 6mL to the conical flask of sterilizing is drawn respectively in superclean bench, 50 DEG C or so of horse is added Bell potato glucose agar medium（PDA）54mL, pours into 4 plates of diameter 9cm after shaking up, be made containing for 4 respective concentrations Malicious culture medium；The Picarbutrazox of different ratio and bellkute series concentration compound solution are made and contained with same method Malicious culture medium.The Penicillium italicum bacterium of 2 days will be cultivated, bacterium block is broken into colony edge with the card punch of diameter 5mm, use transfer needle Bacterium block is moved to the toxic PDA culture medium center being configured in advance, culture in 25 DEG C of incubators is subsequently placed in, often treatment repeats 4 It is secondary.After 3 days, each treatment colony diameter cm is measured using crossing method slide calliper rule, obtain correction and suppress percentage.Each bacterium colony Two diameters are surveyed in right-angled intersection, and bacterium colony size is represented with its average.Then colony growth inhibiting rate is obtained as the following formula：
Then concentration EC in suppressing is calculated with least square method50, then calculate co-toxicity coefficient according to the abundant methods of Sun Yun（CTC）.
Table 3：To the virulence test result of Penicillium italicum
As known from Table 3, the combination preventing and treating Penicillium italicum of Picarbutrazox and bellkute is in proportioning 10:1-1：50 scope In when, co-toxicity coefficient is all higher than 120, illustrates that both show as gain effect at mixture in the range of this.
Experiment 4：The toxicity test of rice seedling blight
Selected from the rice seedling that growing way is consistent, each treatment supplies examination leaf seedling from 3 basins, with potter spray towers in 50PSI pressure Lower spraying, per basin about 5mL, each medicament sets 12 concentration gradients.24h connects bacterium after chemicals treatment, will pick up from the water in field Rice damping-off leaf is uniformly shaken off conidium above rice seedling and is inoculated with, and then rice seedling is put into greenhouse and is trained Support.Morbidity grade scale complete stool after 7d according to rice seedling blight investigates disease index, and calculates prevention effect, then with minimum Square law calculates concentration EC50 in suppressing, then calculates co-toxicity coefficient (CTC) according to the abundant methods of Sun Yun.
Table 4：Virulence test result of the present invention on preventing and treating rice seedling blight
As known from Table 4, Picarbutrazox and bellkute are preventing the weight proportion 10 of rice seedling blight:1-1:50 scope In when, co-toxicity coefficient is all higher than 120, illustrates that both show as gain effect at mixture in the range of this.
2nd, the evaluation of pesticide effectiveness：
When the effect of active compound combinations exceedes the summation of the effect when each reactive compound is administered alone, there is association Same synergistic effect.The predictive role of two kinds of particular combinations of reactive compound can be used so-called " Colby formula " (referring to S.R. Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967,15,20-22) it is calculated as below:If
X is the activity when the reactive compound A that consumption is mg/ha or concentration is mppm is used；
Y is the activity when the reactive compound B that consumption is ng/ha or concentration is nppm is used, and is expressed as accounting for untreated right According to percentage；
E is the activity when the reactive compound A and B that consumption is m and n g/ha or concentration is m and n ppm is used,
So
If the activity of actual observation（O）More than expection activity（E）, then said composition has synergistic effect.
Following biological test example is used to illustrate the present invention.But, the present invention is not limited to these embodiments.
Experiment 5：Epidemic disease is tested（Tomato）The efficacy testing of/protectiveness
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent Close, dilute with water concentrate to required concentration.
In order to test protectiveness activity, young plant is sprayed with certain rate of application with active agent preparations.In sprinkling Coating dry after, plant is inoculated with the aqueous spore suspension of phytophthora infestans.Then the plant is placed on about 20 DEG C, in the incubate box that relative atmospheric humidity is 100%.
3 days after incubation, test result is evaluated.0% represents the drug effect equivalent to control sample, 100% drug effect Indicate and occur without illness.
Reactive compound The rate of application of reactive compound, ppm Actual drug effect, % The desired value % that " Colby formula " is calculated
Picarbutrazox 1 44 -
Picarbutrazox 100 89.4 -
Bellkute 10 0 -
Bellkute 25 14.8 -
Bellkute 50 22.6 -
Bellkute 1000 78.5 -
Picarbutrazox+ bellkutes 100+10 100 89.4
Picarbutrazox+ bellkutes 1+25 69.9 52.3
Picarbutrazox+ bellkutes 1+50 73.5 56.65
Picarbutrazox+ bellkutes 1+1000 84.87 87.96
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of bellkute 10:1-1:It is higher than the drug effect being calculated to the actual drug effect of tomato blight in the range of 50, that is, there is cooperative effect.
Experiment 6：Epidemic disease is tested（Tomato）/ curative efficacy testing
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent Close, dilute with water concentrate to required concentration.
In order to test therapeutical active, the spore suspension of phytophthora infestans is inoculated with to the tomato of 5-6 leaf phases.Then will be described Prevented and treated 18 hours in the incubate box that plant is placed on about 20 DEG C, relative atmospheric humidity is 100%.After air-drying leaf, with activation Compound preparation sprays young plant with certain rate of application, and is sprayed with the degree of the liquid that drips, and then makes in greenhouse Its morbidity.Inoculation investigates occurring degree after 7 days.Test result is evaluated.0% represents the drug effect equivalent to control sample, 100% drug effect indicates occur without illness.
Reactive compound The rate of application of reactive compound, ppm Actual drug effect, % The desired value % that " Colby formula " is calculated
Picarbutrazox 1 44 -
Picarbutrazox 100 84.4 -
Bellkute 10 0 -
Bellkute 25 5 -
Bellkute 50 9 -
Bellkute 1000 71.4 -
Picarbutrazox+ bellkutes 100+10 100 84.4
Picarbutrazox+ bellkutes 1+25 68.8 46.8
Picarbutrazox+ bellkutes 1+50 70.7 49.04
Picarbutrazox+ bellkutes 1+1000 80.3 84
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of bellkute 10:1-1:It is higher than the drug effect being calculated to the actual drug effect of tomato blight in the range of 50, that is, there is cooperative effect.
Experiment 7：Downy mildew is tested（Grape）The efficacy testing of/protectiveness
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent Close, dilute with water concentrate to required concentration.
In order to test protectiveness activity, young plant is sprayed with certain rate of application with active agent preparations.In sprinkling Coating dry after, plant is inoculated with the aqueous spore suspension of Plasmopara viticola.Then the plant is placed on About 20 DEG C, in the incubate box that relative atmospheric humidity is 100%.
3 days after incubation, test result is evaluated.0% represents the drug effect equivalent to control sample, 100% drug effect Indicate and occur without illness.
Reactive compound The rate of application of reactive compound, ppm Actual drug effect, % The desired value % that " Colby formula " is calculated
Picarbutrazox 1 26.9 -
Picarbutrazox 10 54.2 -
Picarbutrazox 50 92.6 -
Bellkute 1 0 -
Bellkute 25 11 -
Bellkute 50 13 -
Bellkute 1000 56.8
Picarbutrazox+ bellkutes 10+1 74.5 54.2
Picarbutrazox+ bellkutes 1+25 57.7 34.9
Picarbutrazox+ bellkutes 1+50 58.1 36.4
Picarbutrazox+ bellkutes 1+1000 66.4 68.42
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of bellkute 10:1-1:It is higher than the drug effect being calculated to the actual drug effect of downy mildew of garpe in the range of 50, that is, there is cooperative effect, and And the effect of cooperative effect is the most obvious.
Experiment 8：Downy mildew is tested（Grape）/ curative efficacy testing
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent Close, dilute with water concentrate to required concentration.
In order to test therapeutical active, the spore suspension of Plasmopara viticola is inoculated with to the grape of 5-6 leaf phases.Then will Prevented and treated 18 hours in the incubate box that the plant is placed on about 20 DEG C, relative atmospheric humidity is 100%.After air-drying leaf, with work Property compound formulation young plant is sprayed with certain rate of application, and sprayed with the degree of the liquid that drips, then in greenhouse In it is fallen ill.Inoculation investigates occurring degree after 7 days.Test result is evaluated.0% represents the medicine equivalent to control sample Effect, 100% drug effect indicates occur without illness.
Reactive compound The rate of application of reactive compound, ppm Actual drug effect, % The desired value % that " Colby formula " is calculated
Picarbutrazox 1 22.9 -
Picarbutrazox 10 48.2 -
Picarbutrazox 100 86.6 -
Bellkute 1 0 -
Bellkute 25 0 -
Bellkute 50 11 -
Bellkute 1000 51.3 -
Picarbutrazox+ bellkutes 10+1 35.8 22.9
Picarbutrazox+ bellkutes 1+25 47.3 22.9
Picarbutrazox+ bellkutes 1+50 53.6 31.4
Picarbutrazox+ bellkutes 1+1000 62.4 62.4
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of bellkute 10:1-1:It is higher than the drug effect being calculated to the actual drug effect of downy mildew of garpe in the range of 50, that is, there is cooperative effect, and And the effect of cooperative effect is the most obvious.
Experiment 9：Antiseptic effect to preserving oranges and tangerines
Treatment oranges and tangerines picking time plucks fruit, rejects disease fruit and wound fruit, and fruit 1min is soaked with treatment liquid.Control clear water dipping.Respectively Dried after treatment leaching fruit, next day loads the plastic box that surrounding is lined with newspaper, normal temperature laboratory storage.Check decayed fruit number within 7 days after treatment And decayed fruit is rejected, while having weighed up fruit weight.And calculate preventive effect.
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of bellkute 10:1-1:In the range of 50, the anti-corrosion to preserving oranges and tangerines, actual drug effect is higher than the drug effect being calculated, that is, there is cooperative effect.
Experiment 10：Damping-off is tested（Paddy rice）/ curative efficacy testing
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent Close, dilute with water concentrate to required concentration.
In order to test therapeutical active, to the spore of the rice seedlings Inoculated Rice rhizoctonia solani of the 5-6 leaf phases in seedling-growing container Water slurry, places 18 hours in the incubate box that 25 DEG C, relative atmospheric humidity are 100%.After air-drying leaf, active ingredient is used Thing preparation sprays plant with certain rate of application, then it is fallen ill in greenhouse.Inoculation investigates occurring degree after 10 days.0% The drug effect equivalent to control sample is represented, 100% drug effect indicates occur without illness.
Reactive compound The rate of application of reactive compound, ppm Actual drug effect, % The desired value % that " Colby formula " is calculated
Picarbutrazox 1 25.9 -
Picarbutrazox 10 51.2 -
Picarbutrazox 100 89.8 -
Bellkute 1 0 -
Bellkute 25 0 -
Bellkute 50 0 -
Bellkute 1000 21.6 -
Picarbutrazox+ bellkutes 10+1 57.1 51.2
Picarbutrazox+ bellkutes 1+25 39.7 25.9
Picarbutrazox+ bellkutes 1+50 38.4 25.9
Picarbutrazox+ bellkutes 1+1000 40.7 41.9
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of Prochloraz 10:1-1:It is higher than the drug effect being calculated to the actual drug effect of rice seedling blight in the range of 50, that is, there is cooperative effect, and And the effect of cooperative effect is the most obvious.

Claims (12)

1. a kind of bactericidal composition, it is characterised in that：The bactericidal composition can including active component Picarbutrazox and hundred , the weight ratio of Picarbutrazox and bellkute is 10:1-1:50, preferably 10:1-1:40, more preferably 10:1- 1:30, it is further preferably 1:1-1:25, it is further preferably 1:1-1:20, more preferably 1:1-1:15, more preferably 1:1-1:10.
2. bactericidal composition according to claim 1, it is characterised in that：The Picarbutrazox and bellkute quality Sum accounts for the 5%-90% of the Bactericidal composite amount of substance, more preferably more preferably 10%-80%, 20%-60%.
3. bactericidal composition according to claim 1, it is characterised in that：The formulation of the bactericidal composition be suspending agent, Seed coat agent, wettable powder, water dispersible granules, microcapsule suspending agent, coated granule, extrusion granule, missible oil, microemulsion, water Emulsion, effervescent tablet, ultra low volume liquids.
4. bactericidal composition according to claim 1, it is characterised in that also comprising filler and/or surfactant.
5. it is a kind of prevent and treat plant pathogen method, it is characterised in that：Bactericidal composition described in claim 1 is acted on into cause In germ and/or its environment, or plant, seed, soil, region, material or space.
6. method according to claim 5, it is characterised in that：Can by the Picarbutrazox described in claim 1 and hundred Must be administered simultaneously or apply respectively or sequential application.
7. the bactericidal composition described in claim 1 is used to prevent and treat the purposes of fungi and bacterium.
8. the bactericidal composition described in claim 1 is used to prevent and treat the purposes of fungi and bacterium in cereal, water fruits and vegetables.
9. the bactericidal composition described in claim 1 is used to protect the use of plant propagation material and the plant organ for then growing On the way.
10. caused a disease in the place preventing and treating soil or cultivation medium of preventing and treating needed for the bactericidal composition described in claim 1 is applied to Or saprophytic fungi and the purposes of bacterium.
Bactericidal composition described in 11. claims 1 is used to prevent and treat the purposes of fruit vegetables storing period disease.
The plant pathogenic fungi of a kind of 12. control plants, plant part, plant propagation material and the plant organ for then growing Method, it is characterised in that：The method is included the bactericidal composition described in claim 1 with agronomy effectively and substantially without plant poison The amount of application of property is applied with Seed Treatment, foliage applying, stem, is impregnated with, instiled, poured into a mould, sprayed, sprayed, dusting, distribution or smoke Etc. method be administered to plant, plant part, plant propagation material or plant growing or needing the soil that grows wherein or In cultivation medium.
CN201511008815.5A 2015-12-30 2015-12-30 A kind of bactericidal composition Pending CN106922722A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201511008815.5A CN106922722A (en) 2015-12-30 2015-12-30 A kind of bactericidal composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201511008815.5A CN106922722A (en) 2015-12-30 2015-12-30 A kind of bactericidal composition

Publications (1)

Publication Number Publication Date
CN106922722A true CN106922722A (en) 2017-07-07

Family

ID=59457505

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201511008815.5A Pending CN106922722A (en) 2015-12-30 2015-12-30 A kind of bactericidal composition

Country Status (1)

Country Link
CN (1) CN106922722A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106982855A (en) * 2016-01-20 2017-07-28 江苏龙灯化学有限公司 A kind of bactericidal composition
CN107372532A (en) * 2017-08-11 2017-11-24 北京科发伟业农药技术中心 The bactericidal composition of the urethane of pyrrole containing tetrazolium

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103999870A (en) * 2014-05-29 2014-08-27 江苏龙灯化学有限公司 Fungicidal composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103999870A (en) * 2014-05-29 2014-08-27 江苏龙灯化学有限公司 Fungicidal composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨吉春等: "国内外杀菌剂进展", 《现代农药》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106982855A (en) * 2016-01-20 2017-07-28 江苏龙灯化学有限公司 A kind of bactericidal composition
CN107372532A (en) * 2017-08-11 2017-11-24 北京科发伟业农药技术中心 The bactericidal composition of the urethane of pyrrole containing tetrazolium

Similar Documents

Publication Publication Date Title
CN103988845B (en) A kind of Fungicidai mixtures
CN106922694A (en) A kind of bactericidal composition
CN106922703A (en) A kind of bactericidal composition
CN106922706A (en) A kind of bactericidal composition
CN105475357B (en) A kind of bactericidal composition
CN106922695A (en) A kind of bactericidal composition
CN106922722A (en) A kind of bactericidal composition
CN106922721A (en) A kind of bactericidal composition
CN106922720A (en) A kind of bactericidal composition
CN106922697A (en) A kind of bactericidal composition
CN106922693A (en) A kind of bactericidal composition
CN106922704A (en) A kind of bactericidal composition
CN106922698A (en) A kind of bactericidal composition
CN103988843B (en) A kind of bactericidal composition
CN103999870B (en) A kind of bactericidal composition
CN107318852A (en) A kind of bactericidal composition
CN103988844B (en) A kind of bactericidal composition
CN106922705A (en) A kind of bactericidal composition
CN106922701A (en) A kind of bactericidal composition
CN106922696A (en) A kind of bactericidal composition
CN103988846B (en) A kind of bactericidal composition
CN106922699A (en) A kind of bactericidal composition
CN106922702A (en) A kind of bactericidal composition
CN106922712A (en) A kind of bactericidal composition
CN106922700A (en) A kind of bactericidal composition

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20170707

RJ01 Rejection of invention patent application after publication