CN106361416A - Intracerebral minimally invasive microscale multi-target-point injection system for stereoscopic direction navigation equipment - Google Patents
Intracerebral minimally invasive microscale multi-target-point injection system for stereoscopic direction navigation equipment Download PDFInfo
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- CN106361416A CN106361416A CN201610851340.4A CN201610851340A CN106361416A CN 106361416 A CN106361416 A CN 106361416A CN 201610851340 A CN201610851340 A CN 201610851340A CN 106361416 A CN106361416 A CN 106361416A
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- intracerebral
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- connecting piece
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3478—Endoscopic needles, e.g. for infusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3415—Trocars; Puncturing needles for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3472—Trocars; Puncturing needles for bones, e.g. intraosseus injections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B2017/3454—Details of tips
- A61B2017/3456—Details of tips blunt
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- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
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- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses an intracerebral minimally invasive microscale multi-target-point injection system for stereoscopic direction navigation equipment. The intracerebral minimally invasive microscale multi-target-point injection system comprises a needle core and an external sleeve needle tube sleeving the needle core, an injection needle end protection sleeve is arranged at the front end of the external sleeve needle tube, a connecting piece is inserted in the rear end of the external sleeve needle tube, a metal connecting piece is connected at the rear end of the connecting piece, the part where the front end of the needle core is connected with the external sleeve needle tube takes the shape of a round blunt nose, a handheld piece is connected to the rear end of the needle core, a rotatable transparent liquid carrier tube connecting piece is arranged in the metal connecting piece in a penetrating manner, and the rear end of the transparent liquid carrier tube connecting piece is connected with a connector of a micro-injection pump through a transparent liquid carrier tube. The intracerebral minimally invasive microscale multiple-target-point injection system has the beneficial effects that the intracerebral minimally invasive microscale multiple-target-point injection system has the advantages of minimally-invasive microscale visual controllable multiple-target-point stereoscopic injection.
Description
Technical field
The present invention relates to technical field of medical equipment, more particularly, to a kind of intracerebral for stereotaxises navigator is minimally invasive
Micro Mutiple Targets injecting systems.
Background technology
Directly drug injection can be treated brain diseasess to intracerebral local lesion, clinically common usage is using common
Radionuclide list target spot is injected to intracerebral by intracerebral puncture needle (diameter 2-3mm, length 19cm) and stereotaxises navigator
In cystic tumor sexually transmitted disease (STD) becomes, to reach the purpose of local radiation treatment.Connect above-mentioned puncture needle pusher using ordinary syringe
Injection product, the volume injecting medicine is often greater than 500ul, and the medicine of this volume is unable to direct injection to brain essence, because
Slight occupation time process will be produced for larger volume injected, the Accessory injury outside therapeutic effect is substantially caused to brain, and only
The drug release of single puncture path list target spot can be carried out in cerebral tissue.
Existing puncture needle does not enable minimally invasive, micro, the Mutiple Targets injection of medicine in brain essence.Additionally, patent inspection
A kind of core apparatus of Suo Faxian " visual minimal removed of intracranial doser " (application publication number cn 104225772 a) are a kind of using
The capillary quartz ampoule (internal diameter is 0.35mm, and external diameter is 0.5mm) tested in toy (big mice).This device can not mate vertical
Body directed navigation equipment, and long quartz ampoule exists and fracture in the risk of intracerebral, be unsuitable for being applied to the mankind, primatess and its
The brain deep injection of his larger animal.
Content of the invention
It is an object of the invention to provide a kind of minimally invasive micro Mutiple Targets injection system of the intracerebral for stereotaxises navigator
System, to overcome the shortcomings of in currently available technology.
For realizing above-mentioned technical purpose, the technical scheme is that and be achieved in that:
A kind of minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator, including nook closing member and be sheathed on pin
Overcoat needle tubing on core, the front end of described overcoat needle tubing is provided with injection needle head end sheath, and the rear end of overcoat needle tubing is inserted with even
Fitting, described connector rear end is connected with metal connecting piece, and the front end of described nook closing member is in circle with the part of overcoat needle tubing joint
Shape is blunt nosed, and the rear end of nook closing member is connected with handpiece, is equipped with rotatable transparent carrier liquid pipe connections in described metal connecting piece,
The rear end of described transparent carrier liquid pipe connections is connected with, by transparent carrier liquid pipe, the union joint being connected with micro-injection pump.
Further, the length of described overcoat needle tubing is 50-300mm, and external diameter is 1mm, and the pipe thickness of overcoat needle tubing is
0.25mm.
Further, the length of described overcoat needle tubing is 198mm.
Further, the length of described nook closing member is 62-312mm, a diameter of 0.4mm.
Further, the length of described nook closing member is 210mm.
Further, described metal connecting piece includes rearward end that leading section is connected and with rearward end even with leading section
The block plate connecing, the length of described leading section is 7mm, leading section is provided with external screw thread, the length of described rearward end is 9mm, institute
The thickness stating block plate is 2mm.
Further, described injection needle head end sheath includes the afterbody being connected in conical head and with head, institute
The length stating head is 10mm, and the length of described afterbody is 8mm.
Further, described transparent carrier liquid pipe is provided with graduation mark, the length of transparent carrier liquid pipe is 1000-3000mm.
Further, described connector is provided with the female thread matching with external screw thread, the length of connector is 15mm.
Beneficial effects of the present invention: directly decrease the contact area of injection needle and cerebral tissue, and with high rigidity and straight
Reduce or eliminate cutting damage during rotation inserting needle, cerebral tissue being caused.In piercing process, the blunt injection needle head end of circle can have
Effect pushes cerebral blood vessel open, reduces the generation even avoiding intracerebral hematoma, and minimum injection injection volume can reach 5ul, very well
The intracerebral occupation time process controlling medicine, by transparent mark graduated pvc carrier fluid pipe it is ensured that injection process
Visuality and controllability.Minimally invasive design so that same enter cranium point multi-angle puncture that be referred to as may so as to many targets can be carried out
Point stereotactic injection.To sum up the present invention has the advantages that minimally invasive, micro, visual controlled, Mutiple Targets stereotactic injection.
Brief description
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below will be to institute in embodiment
Need use accompanying drawing be briefly described it should be apparent that, drawings in the following description be only the present invention some enforcement
Example, for those of ordinary skill in the art, on the premise of not paying creative work, can also obtain according to these accompanying drawings
Obtain other accompanying drawings.
The minimally invasive micro Mutiple Targets note of the intracerebral for stereotaxises navigator that Fig. 1 is described according to embodiments of the present invention
Penetrate the structural representation of system；
Fig. 2 is the overall structure diagram of overcoat needle tubing described according to embodiments of the present invention；
Fig. 3 is the partial enlarged drawing at a in Fig. 2；
Fig. 4 is the structural representation of nook closing member described according to embodiments of the present invention；
Fig. 5 is the structural representation of metal connecting piece described according to embodiments of the present invention；
Fig. 6 is the structural representation of stereotaxises navigator fixture described according to embodiments of the present invention；
Fig. 7 is Fig. 6 top view；
Fig. 8 is the sectional view of Fig. 7.
In figure:
1st, overcoat needle tubing；2nd, nook closing member；3rd, metal connecting piece；4th, injection needle head end sheath；5th, union joint；6th, transparent carrier liquid pipe connects
Part；7th, transparent carrier liquid pipe；8th, stereotaxises navigator fixture；9th, handpiece；10th, connector；31st, leading section；32nd, rear end
Portion；33rd, block plate；81st, centre bore.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation description is it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, all other embodiment that those of ordinary skill in the art are obtained, broadly fall into present invention protection
Scope.
As shown in figures 1-8, a kind of intracerebral for stereotaxises navigator described according to embodiments of the present invention is minimally invasive
Micro Mutiple Targets injecting systems, including nook closing member 2 and be sheathed on overcoat needle tubing 1 on nook closing member 2, the front end of described overcoat needle tubing 1
It is provided with injection needle head end sheath 4, the rear end of overcoat needle tubing 1 is inserted with connector 10, and described connector 10 rear end is connected with gold
Belong to connector 3, the front end of described nook closing member 2 is partly rounded blunt nosed with overcoat needle tubing 1 joint, and the rear end of nook closing member 2 is connected with
Handpiece 9, is equipped with rotatable transparent carrier liquid pipe connections 6 in described metal connecting piece 3, is harder rubber, its
It is inserted in metal connecting piece 3, by metal connecting piece 3 foward dome and rear baffle, by metal connecting piece 3 and transparent carrier liquid pipe
Connector 6 links together, and metal connecting piece 3 can rotate, and the two position can not separate, described transparent carrier liquid pipe connections
6 rear end is connected with, by transparent carrier liquid pipe 7, the union joint 5 being connected with micro-injection pump.
The length of described overcoat needle tubing 1 is 50-300mm, and external diameter is 1mm, and the pipe thickness of overcoat needle tubing 1 is 0.25mm.
Preferably, the length of described overcoat needle tubing 1 is 198mm.
The length of described nook closing member 2 is 62-312mm, a diameter of 0.4mm.Preferably, the length of described nook closing member 2 is 210mm.
Described metal connecting piece 3 includes rearward end 32 that leading section 31 is connected and with rearward end 32 even with leading section 31
The block plate 33 connecing, the length of described leading section 31 is 7mm, and leading section 31 is provided with external screw thread, the length of described rearward end 32
For 9mm, the thickness of described block plate 33 is 2mm.
Described injection needle head end sheath 4 includes the afterbody being connected in conical head and with head, described head
Length is 10mm, most advanced and sophisticated sharp, can puncture cerebral dura mater, the length of described afterbody is 8mm.
Graduation mark is provided with described transparent carrier liquid pipe 7, the length of transparent carrier liquid pipe 7 is 1000-3000mm.
The female thread being matched with external screw thread is provided with described connector 10, the length of connector is 15mm.
Understand the technique scheme of the present invention for convenience, below by way of above-mentioned to the present invention in specifically used mode
Technical scheme is described in detail.
Using this device, need in advance using the commonly disposable sterilized injection having extracted 3-5ml normal saline in advance
Device is rinsed, and keeps being full of normal saline in tube chamber, after union joint 5 is connected to micro-injection pump；
After will be filled with the integral device pumpback 5ul air of normal saline, the medicine of requirement or the dress of cell suspension can be carried out
Carry, the equipment loading medicine or cell suspension is passed through metal connecting piece 3 transparent carrier liquid pipe connections 6 are stable, water-stop
It is fixed on the tail end of overcoat needle tubing 1.
Operation consent carries out 3dmr scanning to big animal or human central nervous system, and application software carries out preoperative plan target
The setting of point, and it is designed into the bore position of cranium point, or the target position of spinal cord；
Conventional big animal or human body, anesthesia, position support, after installation stereotaxises navigator, carry out cranium according to preoperative plan
Bone drilling or spinal lamina are opened；
By stereotaxises navigator fixture 8 firm being installed to after stereotaxises navigator of safety, nook closing member 2 is inserted outer
In trocar tube 1, after overcoat needle tubing 1 and nook closing member 2 stable connection, check that the head end combining both it should be seamless circle obtuse
State, overcoat needle tubing 1 and nook closing member 2 coalition are slow transitted through stereotaxises navigator fixture 8；
Wherein, stereotaxises navigator fixture 8 inserts injection needle in single or upper and lower 2 fixtures and is fixed, and stands
Centre bore 81 internal diameter of body directed navigation equipment fixture 8 is 1+(0.1 mm -0.2mm), meet leksell stereotaxises frame
Fixture, design in ladder sample, each ladder height is 10mm, the 1st ladder design for rectangle, facilitate determination baseline,
2nd ladder external diameter meets orientation folder clamping internal diameter；
Before touching cerebral dura mater and spinal dura mater, injection needle head end sheath 4 is attached to the coalition of overcoat needle tubing 1 and nook closing member 2
Front end, continues slowly to wear out cerebral dura mater or spinal dura mater using the sharpening forward ends of injection needle head end sheath 4 forward；
After penetrating cerebral dura mater or spinal dura mater, suitable rollback overcoat needle tubing 1, nook closing member 2 and injection needle head end sheath 4 coalition, take
Lower injection needle end sheath 4, continues slow rotary sleeve needle tubing 1 and nook closing member 2 coalition, through cerebral dura mater or the hard ridge of perforation
Film, in insertion cerebral tissue or spinal cord, whole inserting needle process should be stable, no vibrating state.
Wherein, metal connecting piece 3, injection needle head end sheath 4, union joint 5, transparent carrier liquid pipe connections 6 and transparent carrier liquid
7 five parts of pipe are mounted entirety, and forward metal connector 3 is placed on outside transparent carrier liquid pipe connections 6, and the two can turn relatively
Dynamic, can be by stable, water-stop for transparent carrier liquid pipe connections 6 tail end being fixed on overcoat needle tubing 1 by metal connecting piece 3；Thoroughly
Bright carrier fluid pipe connections 6 rear water-stop connects transparent carrier liquid pipe 7, and transparent carrier liquid pipe 7 rear end is connected with union joint 5, union joint 5
Continue to connect micro-injection pump.
According to the demand of injection, carry out the micro-injection of each target spot ＞ 5ul it is recommended that the injection scope of each target spot is 5-
40ul；After the completion of an injection target spot, can be by changing the depth in intracerebral for the overcoat needle tubing 1, the straight line realizing single needle road is many
Target spot is injected；And by change needle track and realize the injection of 3-D Multi-Target point it is recommended that needle track quantity be 1-5.
The present invention is in order to reach the purpose of Accessory injury that is minimally invasive, reducing puncture path: 1) require the diameter of injection needle less, its
Diameter range is 12 millimeters, and this design can reduce the contact area of injection needle and cerebral tissue；2) adopt higher stainless of hardness
Steel quality guarantee demonstrate,proves the rigidity of injection needle with straight, when being so rotated into pin in brain essence, can reduce or eliminate as far as possible because of note
Penetrate the cerebral tissue incision that the bending of pin leads to；3) head end of injection needle need to be justified blunt, can push in piercing process head end contact open
Cerebral blood vessel.In order to reduce the occupation time process in the brain essence that injection volume brings, design less needle internal diameter, scope
At 0.2 0.8 millimeters, and advance medicinal liquid using micro-injection pump, the fixing fabric structure injected every time is in 5-50ul.Because above-mentioned
Expedients, operation will greatly be controlled to the Accessory injury of cerebral tissue, same enter cranium point, carry out multi-angle brain deep and wear
Thorn, and combine the depth that adjustment punctures, realize the injection of 3-D Multi-Target point.Injection needle rear end connects transparent pvc pipeline, pipeline subscript
Note scale and numeral, in the process real time drug liquid mobility status of injection.
The present invention can achieve common drug and biological preparation (including neural stem cell etc.) in the focus in brain essence or
Perilesional direct injection.Rely on existing multiple stereotaxises navigation frame apparatus, can achieve that accurately brain essence is interior
Target spot is injected.For brain intraparenchymal injection medicine, need the operation process ensureing injection therapeutic medicine that brain is substantially produced
Minimum Accessory injury.These Accessory injury include: 1) puncture path damages and (includes the Direct perforantes of brain essence are damaged and puncture is said
Blood) and 2) occupation time process in the brain essence brought of the injection volume of injection point.Mutiple Targets brain intraparenchymal injection medicine, can be direct
Increase the region that medicine covers, and on the premise of drug level is certain, increase drug dose.Compared with single target spot injection,
Its medication effect will be more notable, with more Clinical practicability., in bolus infusion processes in brain essence, needs are logical for medicine
Cross visual path to determine the unobstructed of injection needle.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention
Within god and principle, any modification, equivalent substitution and improvement made etc., should be included within the scope of the present invention.
Claims (9)
1. the minimally invasive micro Mutiple Targets injecting systems of a kind of intracerebral for stereotaxises navigator, including nook closing member (2) and set
Overcoat needle tubing (1) on nook closing member (2) it is characterised in that: the front end of described overcoat needle tubing (1) is provided with injection needle head end shield
Set (4), the rear end of overcoat needle tubing (1) is inserted with connector (10), and described connector (10) rear end is connected with metal connecting piece
(3), the front end of described nook closing member (2) and overcoat needle tubing (1) joint is partly rounded blunt nosed, and the rear end of nook closing member (2) is connected with
Handpiece (9), is equipped with rotatable transparent carrier liquid pipe connections (6), described transparent carrier liquid pipe in described metal connecting piece (3)
The rear end of connector (6) is connected with, by transparent carrier liquid pipe (7), the union joint (5) being connected with micro-injection pump.
2. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 1, its
It is characterised by: the length of described overcoat needle tubing (1) is 50-300mm, external diameter is 1mm, the pipe thickness of overcoat needle tubing (1) is
0.25mm.
3. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 2, its
It is characterised by: the length of described overcoat needle tubing (1) is 198mm.
4. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 1, its
It is characterised by: the length of described nook closing member (2) is 62-312mm, a diameter of 0.4mm.
5. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 4, its
It is characterised by: the length of described nook closing member (2) is 210mm.
6. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 1, its
Be characterised by: described metal connecting piece (3) include rearward end (32) that leading section (31) is connected with leading section (31) and with rear
The block plate (33) that end (32) connects, the length of described leading section (31) is 7mm, and leading section is provided with external screw thread on (31), institute
The length stating rearward end (32) is 9mm, and the thickness of described block plate (33) is 2mm.
7. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 1, its
It is characterised by: described injection needle head end sheath (4) includes the afterbody being connected in conical head and with head, described head
Length be 10mm, the length of described afterbody is 8mm.
8. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 1, its
It is characterised by: graduation mark is provided with described transparent carrier liquid pipe (7), the length of transparent carrier liquid pipe (7) is 1000-3000mm.
9. the minimally invasive micro Mutiple Targets injecting systems of the intracerebral for stereotaxises navigator according to claim 1, its
It is characterised by: the female thread being matched with external screw thread is provided with described connector (10), the length of connector (10) is 15mm.
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| CN201610851340.4A CN106361416B (en) | 2016-09-26 | 2016-09-26 | The minimally invasive micro multiple target point injecting systems of intracerebral for stereotaxis navigation equipment |
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| CN201610851340.4A CN106361416B (en) | 2016-09-26 | 2016-09-26 | The minimally invasive micro multiple target point injecting systems of intracerebral for stereotaxis navigation equipment |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112494115A (en) * | 2020-11-26 | 2021-03-16 | 北京益华生物科技有限公司 | Brain stereo-orientation medicine moistening device |
Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002028457A1 (en) * | 2000-10-02 | 2002-04-11 | Genyx Medical, Inc. | Device for delivering non-biodegradable bulking composition to a urological site |
| CN1386552A (en) * | 2002-06-20 | 2002-12-25 | 杨际芝 | Monitoring and therapeutic apparatus for draining and displacing cerebrospinal fluid and pressurizing |
| WO2005039384A2 (en) * | 2003-09-15 | 2005-05-06 | James Guest | Method and system for cellular transplantation |
| EP1782850A1 (en) * | 2005-10-31 | 2007-05-09 | Codman & Shurtleff Inc. | Method of removing a stylette from a catheter |
| CN200939268Y (en) * | 2006-06-17 | 2007-08-29 | 秦惠娣 | Externally feeding-medicine transfusion system with low position connecting tube |
| US20090069814A1 (en) * | 2004-06-24 | 2009-03-12 | Zaleski Edward R | Medical Device for Rapid and Accurate Entry through Soft Tissue and Bone |
| CN201612673U (en) * | 2009-07-20 | 2010-10-27 | 余斌 | Improved peripheral nerve block retaining trocar |
| CN102626337A (en) * | 2012-04-12 | 2012-08-08 | 郑遵成 | Multi-target vertebral canal spinal needle and use method thereof |
| US20120239050A1 (en) * | 2005-11-18 | 2012-09-20 | Linderman Evan D | Multistate-curvature device and method for delivering a curable material into bone |
| CN202699849U (en) * | 2012-07-27 | 2013-01-30 | 娄世锋 | Injection needle in marrow cavity |
| CN203001074U (en) * | 2012-11-15 | 2013-06-19 | 中国人民解放军北京军区总医院 | Minimally invasive hematoma puncture needle |
| US20140088455A1 (en) * | 2003-03-04 | 2014-03-27 | Convatec Technologies Inc. | Apparatus for monitoring intra-abdominal pressure |
| CN104225772A (en) * | 2014-09-25 | 2014-12-24 | 山西医科大学 | Visual minimally-invasive intracranial dosing device |
| CN105013042A (en) * | 2015-07-31 | 2015-11-04 | 中国医科大学附属第一医院 | System for continuously injecting stem cells into minimally-invasive coronary artery blood vessel |
| CN205322383U (en) * | 2016-01-25 | 2016-06-22 | 曹树伟 | Tumour minimal access surgery intervenes treatment needle |
| CN206518584U (en) * | 2016-09-26 | 2017-09-26 | 张广柱 | The minimally invasive micro Mutiple Targets injecting systems of intracerebral for stereotaxis navigation equipment |
-
2016
- 2016-09-26 CN CN201610851340.4A patent/CN106361416B/en active Active
Patent Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002028457A1 (en) * | 2000-10-02 | 2002-04-11 | Genyx Medical, Inc. | Device for delivering non-biodegradable bulking composition to a urological site |
| CN1386552A (en) * | 2002-06-20 | 2002-12-25 | 杨际芝 | Monitoring and therapeutic apparatus for draining and displacing cerebrospinal fluid and pressurizing |
| US20140088455A1 (en) * | 2003-03-04 | 2014-03-27 | Convatec Technologies Inc. | Apparatus for monitoring intra-abdominal pressure |
| WO2005039384A2 (en) * | 2003-09-15 | 2005-05-06 | James Guest | Method and system for cellular transplantation |
| US20090069814A1 (en) * | 2004-06-24 | 2009-03-12 | Zaleski Edward R | Medical Device for Rapid and Accurate Entry through Soft Tissue and Bone |
| EP1782850A1 (en) * | 2005-10-31 | 2007-05-09 | Codman & Shurtleff Inc. | Method of removing a stylette from a catheter |
| US20120239050A1 (en) * | 2005-11-18 | 2012-09-20 | Linderman Evan D | Multistate-curvature device and method for delivering a curable material into bone |
| CN200939268Y (en) * | 2006-06-17 | 2007-08-29 | 秦惠娣 | Externally feeding-medicine transfusion system with low position connecting tube |
| CN201612673U (en) * | 2009-07-20 | 2010-10-27 | 余斌 | Improved peripheral nerve block retaining trocar |
| CN102626337A (en) * | 2012-04-12 | 2012-08-08 | 郑遵成 | Multi-target vertebral canal spinal needle and use method thereof |
| CN202699849U (en) * | 2012-07-27 | 2013-01-30 | 娄世锋 | Injection needle in marrow cavity |
| CN203001074U (en) * | 2012-11-15 | 2013-06-19 | 中国人民解放军北京军区总医院 | Minimally invasive hematoma puncture needle |
| CN104225772A (en) * | 2014-09-25 | 2014-12-24 | 山西医科大学 | Visual minimally-invasive intracranial dosing device |
| CN105013042A (en) * | 2015-07-31 | 2015-11-04 | 中国医科大学附属第一医院 | System for continuously injecting stem cells into minimally-invasive coronary artery blood vessel |
| CN205322383U (en) * | 2016-01-25 | 2016-06-22 | 曹树伟 | Tumour minimal access surgery intervenes treatment needle |
| CN206518584U (en) * | 2016-09-26 | 2017-09-26 | 张广柱 | The minimally invasive micro Mutiple Targets injecting systems of intracerebral for stereotaxis navigation equipment |
Non-Patent Citations (1)
| Title |
|---|
| 张广柱，等: "《神经干细胞多靶点精准脑内移植术》", 《中华神经创伤外科电子杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112494115A (en) * | 2020-11-26 | 2021-03-16 | 北京益华生物科技有限公司 | Brain stereo-orientation medicine moistening device |
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| Publication number | Publication date |
|---|---|
| CN106361416B (en) | 2018-10-19 |
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