CN106264504A - Noninvasive Blood Pressure Measurement System based on finger arteriogram and method - Google Patents
Noninvasive Blood Pressure Measurement System based on finger arteriogram and method Download PDFInfo
- Publication number
- CN106264504A CN106264504A CN201610872396.8A CN201610872396A CN106264504A CN 106264504 A CN106264504 A CN 106264504A CN 201610872396 A CN201610872396 A CN 201610872396A CN 106264504 A CN106264504 A CN 106264504A
- Authority
- CN
- China
- Prior art keywords
- blood pressure
- pulse wave
- finger
- arteriogram
- time
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
- A61B5/02125—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave propagation time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6825—Hand
- A61B5/6826—Finger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Signal Processing (AREA)
- Physiology (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Power Engineering (AREA)
- Vascular Medicine (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
Noninvasive Blood Pressure Measurement System based on finger arteriogram and method, detecting system includes two photocapacitance pulse wave sensors, filter amplification circuit, microprocessor governor circuit, battery module, mobile communication module and cloud platform.Detection method includes gathering the photoplethysmographic signal of 2 before and after same finger tremulous pulse the most simultaneously, after being filtered amplifying, two-way photoplethysmographic signal it is AD converted and character pair is clicked on line position labelling, the wave character point time difference calculating two-way ripple obtains pulse wave translation time, and the relation according to being directly proportional between blood pressure and pulse ripple conduction time sets up linear equation.Finally bring gained pulse wave translation time and the blood pressure data obtained through sphygomanometer into linear equation, demarcate personalized undetermined parameter, new pulse wave translation time is substituted into the blood pressure being calculated testee in the linear equation after determining parameter.The present invention designs light small and exquisite, it is not necessary to use traditional cuff, and test result is accurate.
Description
Technical field
The invention belongs to health monitoring arts, a kind of Noninvasive Blood Pressure Measurement System based on finger arteriogram
And method.
Background technology
In recent years, along with improving constantly of scientific and technological progress and living standard, the life style of people and dietary structure are all
There occurs great variety, result in cardiovascular disease in China in the trend risen year by year.Blood pressure is as important Human Physiology
One of parameter, it is possible to reflection human body cardiovascular function status, has weight at aspects such as medical research, medical diagnosis on disease, Index for diagnosis
Want meaning.
The method measuring blood pressure at present is broadly divided into two kinds: invasive is measured and non-invasive measurement.
Invasive measurement is by the conduit with pressure transducer being inserted directly into patient artery blood vessel to detect its blood pressure
Change, due to the use of advanced medical apparatus and instruments clinically so that the blood pressure detecting mode of intrusive mood is progressively by more hommization, more
Closeness to life and more advanced non-invasion blood pressure detection method are replaced, and are used hardly in routine diagnosis.
Non-invasive measurement is divided into again batch (-type) to measure and continuous way is measured.Batch (-type) measurement method use traditional Ke's formula sound method or
Oscillographic method obtains the pressure value of a certain particular moment, but single measurement is all because being vulnerable to environmental condition, health etc.
Multifactorial impact, thus produce bigger error, it is impossible to fully meet the demand of clinic, and measurement will be by the inflation/deflation of cuff
Carry out, easily cause measured uncomfortable.Noinvasive continuous way measuring method can record the pressure value and can be long-time of often fighting continuously
The change of monitoring blood pressure waveform, provides the foundation of more horn of plenty, therefore in clinical monitoring and monitoring continuously for medical diagnosis on disease treatment
Blood pressure aspect has the unrivaled advantage of traditional method, is the development trend of blood pressure measuring method from now on.
In noinvasive continuous way blood pressure measuring method, the most ripe is volume-compensation method and angiosthenia method.These are two years old
The method of kind needs also exist for using cuff, long-time measurement to be easily caused venous congestion thus affect essence in blood pressure measurement
Degree, also can make measured not feel well.And emerging being tried to achieve by analysis electrocardiosignal and photoplethysmographic trace signal
Pulse wave translation time, and then try to achieve the metering system of blood pressure, owing to electrocardiosignal to be measured can make device overall structure multiple
Miscellaneous, inconvenience uses, and is therefore unfavorable for the portable of sphygomanometer and design for aesthetic.
Summary of the invention
Present invention aims to above-mentioned the problems of the prior art, it is provided that a kind of noinvasive based on finger arteriogram
Blood pressure detecting system and method, this system and method is easy to operate, it is comfortable to use, portability is high, it is possible to meet daily blood pressure prison
Protect demand.
To achieve these goals, present invention Noninvasive Blood Pressure Measurement System based on finger arteriogram includes:
Two the photocapacitance pulse waves simultaneously gathering 2 photoplethysmographic signal before and after same finger tremulous pulse pass
Sensor；
For the filter amplification circuit that the two-way photoplethysmographic signal collected is amplified；
For two-way photoplethysmographic signal is AD converted and character pair is clicked on line position labelling, and
The wave character point time difference calculating two-way ripple obtains pulse wave translation time, according to change and the pulse wave translation time of blood pressure
The relation being directly proportional sets up linear equation, the conduction time of gained pulse wave and the blood pressure data obtained through sphygomanometer is brought into
Linear equation, demarcates personalized undetermined parameter, and is calculated the microprocessor governor circuit of testee's blood pressure；
For real-time for testee blood pressure information is sent to the mobile communication module that cloud platform carries out storing；
For logical to two photocapacitance pulse wave sensors, filter amplification circuit, microprocessor governor circuit and movement
The battery module that letter module is powered.
Two photocapacitance pulse wave sensors are placed with at the finger tip of same finger of testee along tremulous pulse respectively and refer to root
Bifurcation.
Two described photocapacitance pulse wave sensors include the light source for obtaining real-time pulse wave signal and light-receiving
Device, the green glow that light source uses peak wavelength to be 500nm～600nm, it is 530nm～600nm that optical receiver receives peak wavelength.
Described filter amplification circuit is integrated on photocapacitance pulse wave sensor, connects the outfan of optical receiver；Institute
Microprocessor governor circuit, mobile communication module and the battery module stated are integrated in one and are fixed at wrist.
Described filter amplification circuit employing divider resistance arranges 1/2 that DC offset voltage is supply voltage.
Described mobile communication module uses the integration module having GPS, GSM, GPRS function concurrently.
Described battery module connects the voltage regulator being capable of 450mV pressure drop, and has over-voltage protecting function.
Present invention non-invasive blood pressure based on finger arteriogram detection method, comprises the following steps:
1) gather the photoplethysmographic signal of 2 before and after same finger tremulous pulse simultaneously；
2) it is filtered the two-way photoplethysmographic signal collected amplifying；
3) two-way photoplethysmographic signal is AD converted and character pair is clicked on line position labelling, calculate two
The wave character point time difference of road ripple obtains pulse wave translation time, draws according to Thomas poplar and Roger Moens velocity of wave formula
Approximate relation between blood pressure and pulse ripple conduction time: BP=a+b*PTT；In formula, PTT is pulse wave translation time, BP
For blood pressure, a, b represent the personalized undetermined parameter of relation between blood pressure and pulse ripple conduction time；
4) bring the conduction time of gained pulse wave and the blood pressure data obtained through sphygomanometer into linear equation, demarcate individual
Property undetermined parameter, new pulse wave translation time is substituted in the linear equation after determining parameter and is calculated testee's
Blood pressure；
5) by mobile communication module, real-time for testee blood pressure information is sent to cloud platform store.
Described step 3) use medium filtering that the two-way photoplethysmographic signal after AD conversion is removed high-frequency noise
Interference.
Described step 4) personalized undetermined parameter at timing signal by many group experiment averaged.
Compared with prior art, it is permanent to the absorption of light in whole blood circulation due to human body skin, muscle, tissue etc.
Fixed the most constant, and the arterial blood volume in skin under key role in change of beating.Peripheral blood volume when the heart contracts
At most, absorbing amount is maximum for amount, and the light intensity detected is minimum；And when diastole, contrast, the light intensity detected
Maximum, this light intensity just making light absorber receive is pulsating nature change.This intensity variation signal is converted into the signal of telecommunication,
Just human body Digital arteries can be utilized when fluctuating, to cause the difference of reflection light rate to obtain the waveform of pulse wave.The present invention is based on finger
The Noninvasive Blood Pressure Measurement System of arteriogram passes through to gather 2 photoplethysmographic signal before and after same finger tremulous pulse simultaneously,
And then it is poor to obtain pulse wave translation time, and the linear relationship between pulse wave translation time difference and blood pressure is utilized to try to achieve blood pressure
Value, the real-time blood pressure information of testee is sent to cloud platform by mobile communication module and stores the most at last, facilitates mobile phone etc.
Communication equipment is inquired about.The present invention instead of use cuff constraint compressing testee's arm during measuring, and detection process is more
Add comfortable, use wearable design, simple to operate, and global design light small and exquisite, be convenient for carrying, have higher feasible
Property.
Further, it is centrifuged dirty the most remote owing to there is the pulse wave monitored, then pulse wave translation time and arteriotony
Between the biggest trend of dependency, the present invention by two photocapacitance pulse wave sensors respectively along tremulous pulse be placed with testee with
The finger tip of a piece finger and refer to root bifurcation, the blood pressure being calculated testee is more accurate.
Further, photocapacitance pulse wave sensor of the present invention includes the light source for obtaining real-time pulse wave signal and light
Receptor, light source uses peak wavelength to be the green glow of 500nm～600nm, optical receiver receive peak wavelength be 530nm～
600nm.Both peak wavelengths are close, and sensitivity is higher.Due to pulse signal frequency band typically 0.05Hz～200Hz it
Between, signal amplitude is the least, generally in millivolt level level, is easily subject to various signal disturbing, by filter amplification circuit by signal
It is amplified, and using divider resistance to arrange, DC offset voltage is supply voltage 1/2, makes the signal after amplification easily by AD
Gather.
Compared with prior art, present invention non-invasive blood pressure based on finger arteriogram detection method achieves blood pressure and surveys continuously
Amount, the contrast cuff type blood pressure measuring method of based on Korotkoff's Sound or oscillographic method of tradition, it is to avoid single measurement is vulnerable to environment bar
The impact of the factors such as part, health, preferably meets the requirement of real-time of custodial care facility.Survey compared to continuous blood pressure
Volume-compensation method in metering method and angiosthenia method, the present invention uses photocapacitance pulse wave sensor, during measuring not
Re-use cuff constraint testee, make detection process become more comfortable.For testee, move by measuring finger
Arteries and veins information is convenient with the process operation of detection blood pressure, it is not necessary to takes off clothes, and need not be urged to the arm of measured.Additionally,
The present invention select the difference 2 of same finger side tremulous pulse as test point, when both having avoided tremulous pulse information gathering, vessel-like
State changes the impact on pulse wave signal, has given up again ECG signal sampling, has operated fairly simple, and testee is real-time the most at last
Blood pressure information is uploaded to cloud platform, facilitates care provider or measured to check blood pressure information and follow-up by equipment such as mobile phones in real time
Macro-data analysis.
Accompanying drawing explanation
Fig. 1 present invention Noninvasive Blood Pressure Measurement System based on finger arteriogram structured flowchart；
The workflow diagram of Fig. 2 signal analysis and processing of the present invention；
The analysis graph of Fig. 3 pulse wave translation time；
Detailed description of the invention
Seeing Fig. 1, present invention Noninvasive Blood Pressure Measurement System based on finger arteriogram includes that two photocapacitance pulse waves pass
Sensor 1, filter amplification circuit, microprocessor governor circuit 2, cloud platform 3, mobile communication module 4 and battery module 5.
Photocapacitance pulse wave sensor 1 includes light source and optical receiver, is used for obtaining real-time pulse wave signal.Light source uses
Peak wavelength is the green glow of 515nm, and the reception peak wavelength of optical receiver is 565nm, and both peak wavelengths are close, sensitive
Spend higher.Additionally, due to the frequency band of pulse signal is typically between 0.05Hz～200Hz, signal amplitude is the least, typically at millivolt
Level level, is easily subject to various signal disturbing.Therefore it has been used behind low pass filter and by operational amplifier structure at receptor
The filter amplification circuit become, is exaggerated 300～350 times by signal, uses divider resistance to arrange DC offset voltage for electricity simultaneously
The 1/2 of source voltage, enables the signal after amplification to be collected by the A/D module on microprocessor governor circuit 2 well.
Microprocessor governor circuit 2 according to obtain two-way pulse waveform calculate pulse wave conduction time, and according to
Linear relationship between pulse wave translation time and arteriotony draws pressure value.Main control module uses portable terminal main control
Device, is a microcontroller circuit plate, has 14 digital input/output pins, 8 simulation inputs, the resonance of a 16MHz
Device, a SR, it is possible to use USB to turn Transistor-Transistor Logic level and power, it is also possible to utilize external power source to provide voltage, microprocessor
Low cost and performance good, simultaneously meet again the requirement that wearable blood pressure meter miniaturization is integrated.
Mobile communication module 4 for real-time blood pressure information being sent to cloud platform 3, use cloud platform be easy to measured or
Its guardian's real-time query blood pressure information, and mobile communication module 4 uses and has the integration module of GPS, GSM, GPRS function concurrently,
There is standard interface and the GPS function of technical grade, in the place that GSM and gps signal cover, no matter when and where can be real
The seamless tracking of existing different assets.
Battery module 5 is for all module for power supply, optional lithium battery, it is simple to carry use, the power supply electricity of all modules
Pressure all uses 3.7V, and realizes 450mV pressure drop by high-precision voltage regulator, exclusively for low voltage application, and has overvoltage to protect
Protect.
Seeing Fig. 2, present invention non-invasive blood pressure based on finger arteriogram detection method comprises the following steps:
1) gather the photoplethysmographic signal of 2 before and after same finger tremulous pulse, by two photocapacitance pulses simultaneously
Wave sensor 1 is placed with respectively at the finger tip of same finger of testee and refers to root bifurcation；
2) it is filtered the two-way photoplethysmographic signal collected amplifying；
3) by microprocessor governor circuit 2, two-way simulation pulse wave is AD converted, and character pair point is carried out
Position mark, the wave character point time difference calculating two-way ripple obtains pulse wave translation time PTT, according to change and the arteries and veins of blood pressure
The relation that the ripple conduction time PTT that fights is directly proportional sets up linear equation.
4) bring the conduction time of gained pulse wave and the blood pressure data obtained through sphygomanometer into linear equation, demarcate individual
Property undetermined parameter, new pulse wave translation time is substituted in the linear equation after determining parameter and is calculated testee's
Blood pressure；
5) real-time blood pressure information is sent to cloud platform 3, makes measured or its guardian be looked in real time by equipment such as mobile phones
Asking blood pressure information, a large amount of testee's monitoring data samples of cloud platform 3 long term accumulation can provide for public medical department simultaneously
Decision support.
In above-mentioned steps, median filtering algorithm is used to remove High-frequency Interference the pulse wave collected.Pulse wave signal exists
Being easily subject to the interference of high-frequency noise during collection, these noises are mainly by physical activity, muscular tone, collecting device
Residing external condition causes.Medium filtering be first by the shape information after AD conversion as a Serial No., then by sequence
In any value replace with the Mesophyticum of each point value in a neighborhood of this point, eliminate isolated noise spot, allow the value on data point
Closer to actual value.So can effectively remove noise, protection portion sub-signal details such as dicrotic wave, moreover it is possible to the frequency of stick signal
Spectral property.
In above-mentioned steps, the linear relationship between blood pressure and pulse wave is to be obtained by Thomas poplar and Roger Moens velocity of wave formula
Approximate relation between the blood pressure and pulse ripple conduction time gone out: BP=a+b*PTT, wherein, when PTT is pulse transit
Between, BP is blood pressure；A, b represent the personalized undetermined parameter of relation between blood pressure and pulse ripple conduction time.
The change of pulse wave translation time and blood pressure size be changing into direct ratio, and the pulse wave that there is detection be centrifuged dirty more
Far, the trend that the dependency of its pulse wave translation time and blood pressure is the biggest.Due to the difference of individual physiological function, parameter a, b
Value varies with each individual, but for same individuality, their value is stable.In above-mentioned steps, the demarcation of personalized undetermined parameter a, b
It is the actual blood pressure value utilizing two groups of pulse wave time differences of measuring corresponding with two groups, substitutes them in blood pressure and pulse ripple and pass
Lead the corresponding relation formula of time difference, set up linear equation in two unknowns group, solve two unknown-values a, b, then a, b are substituted into full scale equation
Improve out the corresponding relation formula of blood pressure and pulse wave translation time.Certainly, can be reduced by mistake by many group experiment averaged
Difference.
The present invention based on operation principle as follows: when the light beam of certain wavelength is irradiated to finger tip skin surface, light beam will
It is sent to photelectric receiver, in the process owing to being made by the attenuation by absorption of finger tip integumentary musculature and blood by reflection mode
With, the light intensity that photocapacitance pulse wave sensor 1 detects will weaken.Wherein, the absorption of light is existed by skin, muscle, tissue etc.
Whole blood circulation is invariable, and the arterial blood volume in skin under key role in change of beating.Take care
During dirty contraction, peripheral blood cubical content is most, and absorbing amount is maximum, and the light intensity detected is minimum；And when diastole, just
On the contrary, the light intensity detected is maximum, and this light intensity making light absorber receive is pulsating nature change.By this intensity variation
Signal is converted into the signal of telecommunication, and human body Digital arteries just can be utilized to cause the difference of reflection light rate to obtain pulse wave-wave when fluctuating
Shape.This method gathers sign information and avoids the constraint sense that traditional blood pressure measurement method uses cuff to bring to tester, and
Test point is selected in finger tip and makes that measurement is more prone to operation, device is more convenient carries.Obtain the arteries and veins of different 2 of same Digital arteries
Fight waveform, it is possible to obtain the conduction time of pulse wave.Simultaneously as exist between pulse wave translation time and arteriotony
Enough dependencys, and the pulse wave that there is monitoring is centrifuged dirty the most remote, that dependency is the biggest trend.By Thomas poplar and Mo En
This velocity of wave formula show that the approximate relation between blood pressure and PTT can try to achieve pressure value indirectly, has in the process of the present invention
The highest feasibility.
Present invention non-invasive blood pressure based on finger arteriogram detection method is chosen tremulous pulse between finger and, as test point, is used photoelectricity
Hold the waveform of 2 pulse waves before and after pulse wave sensor 1 gathers, as it is shown on figure 3, two-way waveform character pair point before and after Dui Bi
Position relationship, determine pulse wave translation time, the approximate relation between blood pressure and pulse ripple conduction time indirectly try to achieve
Pressure value.
Two photocapacitance pulse wave sensors 1 are placed with testee same along tremulous pulse with fingerstall form by the present invention respectively
The finger tip of root finger and refer to root bifurcation, filter amplification circuit is integrated on photocapacitance pulse wave sensor 1, connects light-receiving
The outfan of device, microprocessor governor circuit 2, mobile communication module 4 and battery module 5 are integrated in one and are fixed at wrist.
The filtered amplification of pulse wave information that photocapacitance pulse wave sensor 1 will collect, is sent to microprocessor governor circuit 2, warp
After main control chip calculation process, the blood pressure information of acquisition is uploaded to cloud platform 3 by mobile communication module 4, facilitates mobile phone etc.
Communication apparatus carries out real-time query.The inventive method is capable of Highgrade integration, is applied to small-sized wearable blood without cuff
Pressure meter, it is achieved the noinvasive of testee's blood pressure is monitored continuously.
Claims (10)
1. a Noninvasive Blood Pressure Measurement System based on finger arteriogram, it is characterised in that including:
Gather two photocapacitance pulse wave sensors of 2 photoplethysmographic signal before and after same finger tremulous pulse simultaneously
(1)；
For the filter amplification circuit that the two-way photoplethysmographic signal collected is amplified；
For two-way photoplethysmographic signal is AD converted and character pair is clicked on line position labelling, and calculate
The wave character point time difference of two-way ripple obtains pulse wave translation time, just becomes with pulse wave translation time according to the change of blood pressure
The relation of ratio sets up linear equation, the conduction time of gained pulse wave and the blood pressure data obtained through sphygomanometer is brought into linearly
Equation, demarcates personalized undetermined parameter, and is calculated the microprocessor governor circuit (2) of testee's blood pressure；
For real-time for testee blood pressure information being sent to the mobile communication module (4) that cloud platform (3) carries out storing；
For to two photocapacitance pulse wave sensors (1), filter amplification circuit, microprocessor governor circuit (2) and movement
The battery module (5) that communication module (4) is powered.
Noninvasive Blood Pressure Measurement System based on finger arteriogram the most according to claim 1, it is characterised in that: described two
Photocapacitance pulse wave sensor (1) is placed with at the finger tip of same finger of testee along tremulous pulse respectively and refers to root bifurcation.
Noninvasive Blood Pressure Measurement System based on finger arteriogram the most according to claim 1 or claim 2, it is characterised in that: described
Two photocapacitance pulse wave sensors (1) include the light source for obtaining real-time pulse wave signal and optical receiver, and light source uses
Peak wavelength is the green glow of 500nm～600nm, and it is 530nm～600nm that optical receiver receives peak wavelength.
Noninvasive Blood Pressure Measurement System based on finger arteriogram the most according to claim 3, it is characterised in that: described filtering
Amplifying circuit is integrated on photocapacitance pulse wave sensor (1), connects the outfan of optical receiver；Described microprocessor master control
Circuit (2), mobile communication module (4) and battery module (5) are integrated in one and are fixed at wrist.
Noninvasive Blood Pressure Measurement System based on finger arteriogram the most according to claim 1, it is characterised in that: described filtering
Amplifying circuit employing divider resistance arranges 1/2 that DC offset voltage is supply voltage.
Noninvasive Blood Pressure Measurement System based on finger arteriogram the most according to claim 1, it is characterised in that: described movement
Communication module (4) uses the integration module having GPS, GSM, GPRS function concurrently.
Noninvasive Blood Pressure Measurement System based on finger arteriogram the most according to claim 1, it is characterised in that: described battery
Module (5) connects the voltage regulator being capable of 450mV pressure drop, and has over-voltage protecting function.
8. a non-invasive blood pressure detection method based on finger arteriogram, it is characterised in that comprise the following steps:
1) gather the photoplethysmographic signal of 2 before and after same finger tremulous pulse simultaneously；
2) it is filtered the two-way photoplethysmographic signal collected amplifying；
3) two-way photoplethysmographic signal is AD converted and character pair is clicked on line position labelling, calculate two-way ripple
Wave character point time difference obtain pulse wave translation time, the blood pressure drawn according to Thomas poplar and Roger Moens velocity of wave formula
And the approximate relation between pulse wave translation time: BP=a+b*PTT；In formula, PTT is pulse wave translation time, and BP is blood
Pressure, a, b represent the personalized undetermined parameter of relation between blood pressure and pulse ripple conduction time；
4) bring the conduction time of gained pulse wave and the blood pressure data obtained through sphygomanometer into linear equation, demarcate personalization
Undetermined parameter, substitutes into the blood being calculated testee in the linear equation after determining parameter by new pulse wave translation time
Pressure；
5) by mobile communication module (4), real-time for testee blood pressure information is sent to cloud platform (3) store.
Non-invasive blood pressure detection method based on finger arteriogram the most according to claim 8, it is characterised in that: described step 3)
Use medium filtering that the two-way photoplethysmographic signal after AD conversion is removed high-frequency noise interference.
Non-invasive blood pressure detection method based on finger arteriogram the most according to claim 8, it is characterised in that: described step
4) personalized undetermined parameter tests averaged at timing signal by many groups.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610872396.8A CN106264504A (en) | 2016-09-30 | 2016-09-30 | Noninvasive Blood Pressure Measurement System based on finger arteriogram and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610872396.8A CN106264504A (en) | 2016-09-30 | 2016-09-30 | Noninvasive Blood Pressure Measurement System based on finger arteriogram and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106264504A true CN106264504A (en) | 2017-01-04 |
Family
ID=57716262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610872396.8A Pending CN106264504A (en) | 2016-09-30 | 2016-09-30 | Noninvasive Blood Pressure Measurement System based on finger arteriogram and method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106264504A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107049289A (en) * | 2017-06-08 | 2017-08-18 | 四川长虹电器股份有限公司 | Based on radial artery ripple without cuff sphygmomanometer and measuring method |
| CN109394184A (en) * | 2018-11-20 | 2019-03-01 | 上海大学 | Pulse wave conduction speed measuring device and method based on two-way pulse wave |
| CN109452944A (en) * | 2017-09-06 | 2019-03-12 | 东北大学 | Blood fluorescence substance non-invasive detection system based on fluorescence pulse wave |
| CN109662699A (en) * | 2018-11-20 | 2019-04-23 | 上海大学 | A kind of two-way physiology signal acquisition device based on photoplethysmography |
| CN110301907A (en) * | 2019-06-25 | 2019-10-08 | 浙江工业大学 | A kind of wearable pulse wave detection device and blood pressure detecting method |
| WO2019227468A1 (en) * | 2018-06-01 | 2019-12-05 | Vita-Course Technologies Co., Ltd. | Methods and systems for pulse transit time determination |
| CN111150385A (en) * | 2020-01-15 | 2020-05-15 | 上海科技大学 | Wearable blood flow velocity sensor based on piezoelectric film |
| CN111686011A (en) * | 2020-05-08 | 2020-09-22 | 周禹光 | Intelligent medical auxiliary equipment |
| CN112105293A (en) * | 2018-05-08 | 2020-12-18 | 皇家飞利浦有限公司 | Apparatus and method for determining blood pressure measurements and computer program product |
| CN112998674A (en) * | 2021-02-22 | 2021-06-22 | 天津工业大学 | Continuous blood pressure measuring device and self-calibration method |
| CN113706984A (en) * | 2021-08-06 | 2021-11-26 | 西安交通大学 | Synchronous analog calibration device and method for blood pressure and reflection type photoelectric accumulated wave |
| CN114271800A (en) * | 2021-12-01 | 2022-04-05 | 西北工业大学 | Non-invasive continuous blood pressure monitoring method in office environment and application |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2260886A1 (en) * | 2008-04-09 | 2010-12-15 | Asahi Kasei Kabushiki Kaisha | Blood pressure estimating device and blood pressure estimating method |
| CN102688024A (en) * | 2012-04-24 | 2012-09-26 | 北京大学 | Blood pressure noninvasive measuring method |
| CN104173036A (en) * | 2014-09-11 | 2014-12-03 | 重庆大学 | Pulse wave acquisition device, and non-invasive blood pressure continuous beat-to-beat measuring system and method |
| CN104382571A (en) * | 2014-10-28 | 2015-03-04 | 李久朝 | Method and device for measuring blood pressure upon radial artery pulse wave conduction time |
| US9408542B1 (en) * | 2010-07-22 | 2016-08-09 | Masimo Corporation | Non-invasive blood pressure measurement system |
-
2016
- 2016-09-30 CN CN201610872396.8A patent/CN106264504A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2260886A1 (en) * | 2008-04-09 | 2010-12-15 | Asahi Kasei Kabushiki Kaisha | Blood pressure estimating device and blood pressure estimating method |
| US9408542B1 (en) * | 2010-07-22 | 2016-08-09 | Masimo Corporation | Non-invasive blood pressure measurement system |
| CN102688024A (en) * | 2012-04-24 | 2012-09-26 | 北京大学 | Blood pressure noninvasive measuring method |
| CN104173036A (en) * | 2014-09-11 | 2014-12-03 | 重庆大学 | Pulse wave acquisition device, and non-invasive blood pressure continuous beat-to-beat measuring system and method |
| CN104382571A (en) * | 2014-10-28 | 2015-03-04 | 李久朝 | Method and device for measuring blood pressure upon radial artery pulse wave conduction time |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107049289A (en) * | 2017-06-08 | 2017-08-18 | 四川长虹电器股份有限公司 | Based on radial artery ripple without cuff sphygmomanometer and measuring method |
| CN109452944A (en) * | 2017-09-06 | 2019-03-12 | 东北大学 | Blood fluorescence substance non-invasive detection system based on fluorescence pulse wave |
| CN109452944B (en) * | 2017-09-06 | 2023-08-15 | 东北大学 | Blood fluorescent substance noninvasive detection system based on fluorescent pulse wave |
| CN112105293A (en) * | 2018-05-08 | 2020-12-18 | 皇家飞利浦有限公司 | Apparatus and method for determining blood pressure measurements and computer program product |
| CN112203582A (en) * | 2018-06-01 | 2021-01-08 | 深圳市长桑技术有限公司 | Pulse propagation time determination method and system |
| WO2019227468A1 (en) * | 2018-06-01 | 2019-12-05 | Vita-Course Technologies Co., Ltd. | Methods and systems for pulse transit time determination |
| CN112203582B (en) * | 2018-06-01 | 2024-04-16 | 深圳市长桑技术有限公司 | Pulse propagation time determination method and system |
| CN109394184A (en) * | 2018-11-20 | 2019-03-01 | 上海大学 | Pulse wave conduction speed measuring device and method based on two-way pulse wave |
| CN109662699A (en) * | 2018-11-20 | 2019-04-23 | 上海大学 | A kind of two-way physiology signal acquisition device based on photoplethysmography |
| CN110301907A (en) * | 2019-06-25 | 2019-10-08 | 浙江工业大学 | A kind of wearable pulse wave detection device and blood pressure detecting method |
| CN111150385A (en) * | 2020-01-15 | 2020-05-15 | 上海科技大学 | Wearable blood flow velocity sensor based on piezoelectric film |
| CN111686011B (en) * | 2020-05-08 | 2022-04-26 | 周禹光 | Intelligent medical auxiliary equipment |
| CN111686011A (en) * | 2020-05-08 | 2020-09-22 | 周禹光 | Intelligent medical auxiliary equipment |
| CN112998674A (en) * | 2021-02-22 | 2021-06-22 | 天津工业大学 | Continuous blood pressure measuring device and self-calibration method |
| CN113706984A (en) * | 2021-08-06 | 2021-11-26 | 西安交通大学 | Synchronous analog calibration device and method for blood pressure and reflection type photoelectric accumulated wave |
| CN114271800A (en) * | 2021-12-01 | 2022-04-05 | 西北工业大学 | Non-invasive continuous blood pressure monitoring method in office environment and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106264504A (en) | Noninvasive Blood Pressure Measurement System based on finger arteriogram and method | |
| CN105943005B (en) | The non-invasive blood pressure detection device mixed based on photoelectricity green light pulse with electrocardiogram | |
| CN110251105A (en) | A kind of non-invasive blood pressure measuring method, device, equipment and system | |
| CN103892818B (en) | A kind of non-invasive central arterial blood pressure measuring method and equipment | |
| CN108186000B (en) | Real-time blood pressure monitoring system and method based on ballistocardiogram signal and photoelectric signal | |
| CN103690152B (en) | A kind of arterial elasticity apparatus for evaluating based on pulse analytical | |
| CN103330550A (en) | Automatic three-portion and nine-pulse-taking information acquisition and recognition device and method of MEMS hydraulic transmission touch | |
| CN104027108B (en) | A kind of optics electrocardio, pulse comprehensive detection device | |
| CN106901705A (en) | A kind of unaware human Body Physiology Multi-parameter harvester and acquisition method and application | |
| CN101224107A (en) | Method for measuring blood pressure and oxygen, and device thereof | |
| CN104382571A (en) | Method and device for measuring blood pressure upon radial artery pulse wave conduction time | |
| CN103385702A (en) | Non-invasive blood pressure continuous detection device and method | |
| CN104382602A (en) | Multi-parameter intelligent physiological detection glove | |
| CN107961001A (en) | Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis | |
| CN204121004U (en) | A kind of pulse diagnostic information acquisition device in conjunction with multiple pressure-type sensor | |
| Oreggia et al. | Physiological parameters measurements in a cardiac cycle via a combo PPG-ECG system | |
| CN202920160U (en) | Traditional Chinese medicine pulse condition collection system | |
| CN103610454B (en) | Blood pressure measurement method and system | |
| CN113509160A (en) | Continuous non-invasive blood pressure monitoring method and device | |
| CN206007239U (en) | SCM Based electronic sphygmograph | |
| CN108742572A (en) | blood pressure monitoring device, method and system | |
| CN107773223A (en) | A kind of online finger instrument for obtaining pulse wave and acquisition pulse wave peak shape parameter method | |
| CN210095711U (en) | Noninvasive continuous blood pressure measuring equipment | |
| CN104027097A (en) | Vascular function noninvasive detecting method and device | |
| CN105769139A (en) | Pulse signal acquisition and data wireless transmission device located on fingernail |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170104 |