CN105943085A - Method for non-invasive measurement of right ventricular pressure and pulmonary artery pressure method - Google Patents
Method for non-invasive measurement of right ventricular pressure and pulmonary artery pressure method Download PDFInfo
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- CN105943085A CN105943085A CN201610390014.8A CN201610390014A CN105943085A CN 105943085 A CN105943085 A CN 105943085A CN 201610390014 A CN201610390014 A CN 201610390014A CN 105943085 A CN105943085 A CN 105943085A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/04—Measuring blood pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
- A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
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Abstract
The invention relates to a method for non-invasive measurement of right ventricular pressure and pulmonary artery pressure method. The method comprises the following steps of obtaining a bicuspid valve horizontal left ventricle short-axis two-dimensional ultrasonic image; drawing points and interventricular septum, a fitting curve of an arc-shaped interventricular septum is formed, the curvature radius and an arc length of the fitting curve are worked out; on the basis of the tubular hypothesis formula of the laplace's theorem, and the left and right ventricle wall pressure is obtained through calculation. Accordingly, non-invasive measurement, ventricular pressure monitoring and pulmonary artery pressure monitoring can be achieved by researching the ventricular wall curvature changes of left and right ventricles.
Description
[technical field]
The present invention relates to medical imaging applied technical field, specifically, be a kind of Non-invasive detection right ventricle
Pressure and the method for pulmonary artery pressure.
[background technology]
Right heart failure and the concealment of acute and chronic pulmonary hypertension onset, subtle.Obvious clinical condition once occurs
Shape, disease progression is rapid, and prognosis is poor, and mortality rate is high.Especially patients with acute pulmonary embolism mortality rate is higher.
The accurate evaluation of this type of individual with pulmonary pressure and right ventricle's pressure need to be raced against time, and clinical intervention needs the most as early as possible.Mesh
Before, the goldstandard of right ventricular pressure and pulmonary artery pressure detection is cardiac catheter and pulmonary artery catheter technology.The method has
Wound, use expensive, not reproducible, clinical practice is subject to certain restrictions.Meanwhile, cardiac catheter and lung
Ductus arteriosus operation itself can cause serious complication such as false aneurysm, room to quiver, pulmonary embolism, go out
Blood and infarction etc..At present, the non-invasive methods of right ventricle and pulmonary artery pressure there is not yet relevant report.Therefore,
Noninvasive evaluation cardiac function and estimation pulmonary artery pressure are not only the Medical Technology of a kind of novelty, and greatly
Reduce Iatrogenic injury and bring secondary injury to patient.
According to basic physics principle, the curvature of arc interventricular septum can reflect that left and right chamber pressure is poor.Heart is received
Contracting and diastole campaign cause left and right chamber pressure difference to change, and then cause interventricular septum curvature to change.End is shunk in left room
Pressure can be obtained by noninvasive brachial artery pressure, and left room can obtain (room by respirometric breast pressure diastasis
Interval swung with breathing cycle or breast buckling, and reflection left and right chamber pressure difference is with breast buckling.Breast pressure can be passed through
Noninvasive pressure of breathing obtains).Therefore, obtain left room according to the contraction of left room, diastole campaign and respiratory movement to receive
Contractive pressure and diastolic pressure, by detection cardiac cycle difference phase and the interventricular septum radian (curvature) of phase of not sharing a common fate
Change can estimate right ventricle end pressure (pulmonary artery), right ventricular diastolic pressure and left ventricular end diastolic presssure (lung capillary
Blood vessel wedge pressure).
[summary of the invention]
It is an object of the invention to the research by the locular wall Curvature varying to left and right room, it is achieved the Non-invasive detection heart
Chamber pressure, pulmonary artery pressure, provide a kind of Non-invasive detection right ventricle pressure and the method for pulmonary artery pressure for reaching above-mentioned purpose.
For achieving the above object, the present invention adopts the technical scheme that: a kind of Non-invasive detection right ventricle pressure and lung move
The method of pulse pressure, comprises the following steps:
A. in left room short axis view, store air-breathing respectively and inhale mutually and expiratory phase mitral value level diastasis or contraction
The two-dimensional ultrasonic image in latter stage;
B. the interventricular septum in above-mentioned image or locular wall are carried out described point to delineate, form arc interventricular septum or locular wall
Matched curve, calculates radius of curvature and the arc length of matched curve;
C. the tubulose combining laplace's theorem assumes formula: P=T/R, is obtained by above-mentioned radius of curvature substitution formula
Obtain transmural pressure strong, P in formula: additional pressure (transmural pressure is strong), R: tubular radius, T: elastic material
The material coefficient of tension.
In step b, the computational methods of the formation of matched curve and radius of curvature thereof and arc length have two kinds, wherein,
Concretely comprising the following steps of method one:
The first step, traces two points on interventricular septum or locular wall, respectively as beginning and end, draws by two
The line segment of point and the median vertical line of this line segment,
Second step, traces the intersection point on median vertical line and arc interventricular septum or locular wall, by starting point, terminal and
These 3, intersection point simulates curvilinear circular, and the size of the radius value suitably regulating this curvilinear circular improves matching
Degree,
3rd step, is calculated radius of curvature and the arc length of matched curve circle;
Concretely comprising the following steps of method two:
The first step, traces several points along interventricular septum side, left room or side, right ventricle,
Second step, selects any three in above-mentioned tracing a little respectively, simulates different curvilinear circular, and count
Calculate radius of curvature and the arc length of each curvilinear circular,
All radius of curvature obtained above and arc length are averaged by the 3rd step respectively, obtain average radius circle,
Record radius of curvature and the arc length of this circle.
The invention has the advantages that:
1, the inventive method realizes noninvasive right ventricular pressure and pulmonary artery pressure inspection, have noinvasive, repeatable,
The advantages such as inspection fee is low.Meanwhile, this method can graft on existing ultrasoundcardiogram quantitative assessing index,
Realize the real-time monitoring of right ventricular pressure and pulmonary artery pressure.
2, the inventive method can help to solve problems with: by each sections locular wall radius of curvature to left room
Research can evaluate the abnormal change of regional wall;Change by interventricular septum Yu left room free wall radius of curvature
Change, it is judged that left and right chamber pressure changes;By the research of the locular wall Curvature varying of room, left and right can be evaluated the left heart
Room, right ventricle, the pressure change of pericardial cavity and pressure;By the research of the locular wall Curvature varying to room, left and right,
Can be with the left room of non-invasive measurement, right ventricular end diastolic pressure;By the research of the locular wall Curvature varying to room, left and right,
Can be with Non-invasive detection ventricular pressure, pulmonary artery pressure.
[accompanying drawing explanation]
Accompanying drawing 1 is the inventive method implementing procedure figure.
Accompanying drawing 2 is ventricle wall two-dimensional ultrasonic image.
Accompanying drawing 3 is curve matching schematic diagram.
Accompanying drawing 4 is schematic diagram matched curve being traced median vertical line with interventricular septum camber line intersection point.
Accompanying drawing 5 is the schematic diagram that described point delineates interventricular septum camber line.
[detailed description of the invention]
The detailed description of the invention provided the present invention below in conjunction with the accompanying drawings elaborates.
As shown in Figure 1, a kind of Non-invasive detection right ventricle pressure and the method for pulmonary artery pressure, comprise the following steps:
A. in left room short axis view, end-systole and mitral value level ventricle short axle two dimension diastasis are stored respectively
Ultrasonoscopy, and air-breathing inhales mutually and the expiratory phase ED two-dimensional ultrasonic image of chordae tendineae of mitral valve level
(as shown in Figure 2);
B. above-mentioned image interventricular septum or locular wall described point are delineated, form arc interventricular septum or the matched curve of locular wall,
Calculate radius of curvature and the arc length of matched curve;
C. the tubulose combining laplace's theorem assumes formula: P=T/R, and above-mentioned radius of curvature is substituted into formula
Acquisition transmural pressure is strong, P in formula: additional pressure (transmural pressure is strong), R: tubular radius, T: elastic material
The material coefficient of tension.
In above-mentioned steps b, the computational methods of the formation of matched curve and radius of curvature thereof and arc length have two kinds.
Concretely comprising the following steps (as shown in Figure 4) of method one:
The first step, traces two points, respectively as beginning and end, draws the line segment by 2 and this line
The median vertical line of section;
Second step, traces median vertical line and arc interventricular septum or the intersection point of locular wall, by starting point, terminal and friendship
Point these 3 simulates curvilinear circular, and the size of the radius value suitably regulating this curvilinear circular improves fitting degree.
3rd step, is calculated radius of curvature and the arc length of fitting circle curve.
Concretely comprising the following steps of method two:
The first step, traces several points along interventricular septum side, left room or side, right ventricle;
Second step, selects any three in above-mentioned tracing a little respectively, simulates different curvilinear circular, and count
Calculate radius of curvature and the arc length of each curvilinear circular.
All radius of curvature obtained above and arc length are averaged by the 3rd step respectively, obtain average radius circle,
Record radius of curvature and the arc length of this circle.
The above is only the preferred embodiment of the present invention, it is noted that common for the art
Technical staff, on the premise of without departing from the inventive method, it is also possible to makes some improvement and supplements, these
Improve and supplement and also should be regarded as protection scope of the present invention.
Claims (2)
1. a Non-invasive detection right ventricle pressure and the method for pulmonary artery pressure, it is characterised in that described method includes
Following steps:
A. in left room short axis view, store air-breathing respectively and inhale mutually and expiratory phase mitral value level diastasis or contraction
The two-dimensional ultrasonic image in latter stage;
B. the interventricular septum in above-mentioned image or locular wall are carried out described point to delineate, form arc interventricular septum or the plan of locular wall
Close curve, calculate radius of curvature and the arc length of matched curve;
C. the tubulose combining laplace's theorem assumes formula: P=T/R, is obtained by above-mentioned radius of curvature substitution formula
Obtain transmural pressure strong, P in formula: additional pressure (transmural pressure is strong), R: tubular radius, T: elastic material
The material coefficient of tension.
A kind of Non-invasive detection right ventricle the most according to claim 1 pressure and the method for pulmonary artery pressure, its feature
Being, in step b, the computational methods of the formation of matched curve and radius of curvature thereof and arc length have two kinds, its
In, concretely comprising the following steps of method one:
The first step, traces two points on interventricular septum or locular wall, respectively as beginning and end, draws by two
The line segment of point and the median vertical line of this line segment,
Second step, traces the intersection point on median vertical line and arc interventricular septum or locular wall, by starting point, terminal and
These 3, intersection point simulates curvilinear circular, and the size of the radius value suitably regulating this curvilinear circular improves matching
Degree,
3rd step, is calculated radius of curvature and the arc length of fitting circle curve;
Concretely comprising the following steps of method two:
The first step, traces several points along interventricular septum side, left room or side, right ventricle,
Second step, selects any three in above-mentioned tracing a little respectively, simulates different circular curves, and count
Calculate radius of curvature and the arc length of each circular curve,
All radius of curvature obtained above and arc length are averaged by the 3rd step respectively, obtain average radius circle,
Record radius of curvature and the arc length of this circle.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113344897A (en) * | 2021-06-24 | 2021-09-03 | 推想医疗科技股份有限公司 | Lung image caliber measuring method and device and image processing method and device |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113344897A (en) * | 2021-06-24 | 2021-09-03 | 推想医疗科技股份有限公司 | Lung image caliber measuring method and device and image processing method and device |
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