CN105688303A - Portable blood purifying system bubble monitoring device and method - Google Patents

Portable blood purifying system bubble monitoring device and method Download PDF

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Publication number
CN105688303A
CN105688303A CN201610028600.8A CN201610028600A CN105688303A CN 105688303 A CN105688303 A CN 105688303A CN 201610028600 A CN201610028600 A CN 201610028600A CN 105688303 A CN105688303 A CN 105688303A
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China
Prior art keywords
bubble
signal
comparator
alarm device
purifying system
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CN201610028600.8A
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李平
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Beijing Meder Medical Science & Technology Co
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Beijing Meder Medical Science & Technology Co
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Priority to CN201610028600.8A priority Critical patent/CN105688303A/en
Publication of CN105688303A publication Critical patent/CN105688303A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3626Gas bubble detectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/18General characteristics of the apparatus with alarm

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses a portable blood purifying system bubble monitoring device comprising a supersonic wave bubble detector, a signal processor, a comparator, a CPU processor and an alarm device; the supersonic wave bubble detector is arranged on two sides of a blood conduit; the signal processor is connected with the supersonic wave bubble detector so as to carry out interference signal elimination and thus forming regular rectangular signal pulse width Tc; the comparator is connected with the signal processor; the CPU processor is respectively connected with the comparator and the alarm device. The comparator compares the rectangular signal pulse width Tc with a set large bubble threshold values Tc1 and a non-bubble/microscale bubble threshold value Tc0; when Tc>=Tc1, the alarm device is started; when the Tc<=Tc0, direct filtering is carried out; when Tc0<Tc<Tc1, accumulation calculating is carried out, and the alarm device is started when the cumulant in each minute is bigger than the set value T. The reliability of the bubble monitoring device can be largely enhanced, thus ensuring bubble timely and accurate alarming, and effectively shielding various interferences.

Description

For the bubble monitoring device in Portable blood purifying system and method
Technical field
The present invention relates to field of blood purification, particularly for the bubble monitoring device in Portable blood purifying system and method。
Background technology
Bubble detector is as predominantly detecting device on present dialysis machine, Main Function is whether the venous return section in real time, continuously, reliably detected in whole dialysis procedure at blood extracorporeal circulation has bubble to exist, prevent gas from entering and cause gas embolism in the patient, it is ensured that the safety of dialysis patient。When there being air to occur, machine sends alarm signal, makes blood clip closure, stops in blood flowing patient body。
General conventional detection method has three kinds: (1) capacitive detector;(2) infrared light electric-type detector;(3) ultrasonic type detector。Owing to supersonic detector has strong penetration capacity, strong anti-interference ability, reliability is high, the feature such as attenuation degree is obvious in liquids and gases, detect the bubble in liquid line by its principle to be easiest to realize, and highly sensitive, reliable and stable, moreover it is possible to detect the continuous minute bubbles that gap is only small, therefore adopt supersonic detectors as bubble detector more at present。
The Cleaning Principle of supersonic detector: utilizing sound wave to reflect and reflect on the interface of different medium, make conduction be affected, intensity of sound will be greatly reduced。Acoustical signal is inner at bubble-free liquid (blood), and attenuation rate is only small, and major part is received by receptor;The bigger output voltage signal of receiving intensity is also bigger。Once there be bubble to exist in liquid, major part acoustic signals will be reflected by bubble and reflect, and signal is significantly decayed, and the intensity of sound that now receptor receives will reduce, and output voltage signal also diminishes therewith。The degree that output voltage signal diminishes can reflect the size of bubble volume。The bubble (or more same volume bubble) that volume is more big, the change causing voltage is more big。
The structure diagram of supersonic detector is as it is shown in figure 1, transmitting terminal 1 and receiving terminal 2 are arranged on the both sides of blood catheter 3, and Cleaning Principle is as shown in Figure 2。
Bubble detection head is arranged in blood circuit, and employing is transmission ultrasonic wave detection method, is respectively provided with ultrasonic emitting in the both sides of blood catheter and receives device;It is provided with radiating circuit in transmitting terminal, in receiving terminal, is provided with reception circuit。During bubble-free, ultrasound wave arrives test side by medium blood, and the loss of sound wave is little, is converted to the signal of telecommunication through transducer, it can be clearly seen that, with oscillograph, the sine wave that frequency is 1MHz, this signal makes a gift to someone logic circuit on circuit boards after treatment to ensure the normal operation of loom;When blood occurs bubble, owing to sound wave major part is reflected, so in test side almost without sound wave, reflection be then original signal of telecommunication to circuit without, becoming low level, this change will make logic circuit level that corresponding upset occurs, and control machine and send sound and light alarm and make blood clip closure, blood pump stall simultaneously, stops bubble to enter people's human body with draining blood and causes thromboembolism to jeopardize patients ' lives safety。
There is following defect in existing bubble detector:
First, the detection threshold of existing air bubble sensor is typically in demarcating when sensor dispatches from the factory, when in blood, one has bubble then to report to the police immediately, very sensitive, but this has resulted in certain defect for portable dialysis machine, because portable dialysis machine design in order that in the wild or motion in treatment and design, instrument is often in the middle of rocking, at this moment the bubble that in blood, the continuous output of meeting is small, and move along with blood flow, thus cause constantly reporting to the police and cannot using of air bubble sensor;
Second, owing to rocking of instrument can produce a lot of interference signals, affect the normal of sensor and be suitable for。
Summary of the invention
For the weak point existed in the problems referred to above, the present invention is provided to the bubble monitoring device in Portable blood purifying system and method。
For achieving the above object, the present invention provides a kind of for the bubble monitoring device in Portable blood purifying system, including ultrasonic bubble detector, signal processor, comparator, CPU processor and alarm device;
Described ultrasonic bubble detector includes discharger and receives device, and described discharger and reception device are arranged on the both sides of blood catheter;
Described signal processor is connected with receiving device, eliminates the rectangular signal pulsewidth Tc of also formation rule for the ultrasonic pulse signal received carries out interference signal;
Described comparator is connected with signal processor, and described CPU processor is connected with described comparator, alarm device respectively;Described comparator is for comparing the threshold values of rectangular signal pulsewidth Tc Yu setting, and being provided with air pocket threshold values Tc1, bubble-free and micro bubble threshold values in comparator is Tc0, as Tc Tc1, is directly entered CPU processor and starts alarm device;As Tc Tc0, directly filter out;As Tc0 Tc Tc1, enter CPU processor and carry out accumulation calculating, starting alarm device when cumulant per minute is more than setting value T。
As a further improvement on the present invention, described signal processor includes interference signal processing module and signal shaping module, and described interference signal processing module is connected with described reception device, and described signal shaping module is connected with described interference signal processing module。
As a further improvement on the present invention, described interference signal processing module includes one or more in active bandwidth-limited circuit, Schmidt trigger and comparator。
As a further improvement on the present invention, described CPU processor includes accumulator, calculates for the minute bubbles of Tc0 rectangular signal pulsewidth Tc Tc1 are carried out accumulation。
The invention also discloses a kind of for the bubble monitoring method in Portable blood purifying system, including:
Ultrasonic pulse signal A launched by step one, discharger, receives device and receives the ultrasonic pulse signal B through blood catheter;
Step 2, ultrasonic pulse signal B is carried out interference signal eliminate, and to eliminate interference after signal carry out shaping, the rectangular signal of formation rule and the pulsewidth of rectangular signal are Tc;
Step 3, the minute bubbles threshold values Tc0, the air pocket threshold values Tc1 that signal pulsewidth Tc and comparator are set by comparator are compared:
Tc Tc1, is directly entered CPU processor and starts alarm device;
Tc Tc0, directly filters out;
Tc0 Tc Tc1, enters CPU processor and carries out accumulation calculating, starting alarm device when cumulant per minute is more than setting value T。
As a further improvement on the present invention, described threshold values Tc1 is 20-100ul, Tc0 is 5-20ul, and Tc1 Tc0。
As a further improvement on the present invention, described setting value T is 1-3ml/ minute。
As a further improvement on the present invention, described startup alarm device includes starting sound and light alarm, and blood presss from both sides Guan Bi, blood pump stall and heparin pump stall。
Compared with prior art, the invention have the benefit that
Disclosed by the invention for the bubble monitoring device in Portable blood purifying system and method, by arranging signal processing module, the interference signal in ultrasonic signal is eliminated, effectively shields the various interference in actual application environment;Signal shaping after simultaneously elimination being disturbed is rectangular signal, by arranging two kinds of threshold values Tc0, Tc1 in comparator, judge the size of bubble, then directly report to the police when pulsewidth is not less than Tc1, it is not more than Tc0 then directly to ignore, added up by CPU processor between Tc0, Tc1, reach certain value and then start alarm device。The reliability of the bubble monitoring device of the present invention obtains and is greatly reinforced, and especially when waving, vibrating battlefield, field, the difference with former air bubble sensor clearly, namely ensure that the promptly and accurately warning of bubble, effectively shields again various interference;Meanwhile, the present invention can pass through to adjust threshold values, changes the sensitivity of instrument。
Accompanying drawing explanation
Fig. 1 is the structural representation of supersonic detector in background of invention;
Fig. 2 is the Cleaning Principle figure of supersonic detector in background of invention;
Fig. 3 is the frame diagram of bubble monitoring device disclosed in an embodiment of the present invention;
Fig. 4 is the flow chart of bubble monitoring method disclosed in an embodiment of the present invention。
In figure: 1, transmitting terminal;2, receiving terminal;3, blood catheter;4, ultrasonic bubble detector;4-1, discharger;4-2, reception device;5, signal processor;5-1, interference signal processing module;5-2, signal shaping module;6, comparator;7, CPU processor;8, alarm device。
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with the accompanying drawing in the embodiment of the present invention, technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is a part of embodiment of the present invention, rather than whole embodiments。Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art obtain under the premise not making creative work, broadly fall into the scope of protection of the invention。
Below in conjunction with accompanying drawing, the present invention is described in further detail:
Embodiment 1: as it is shown on figure 3, of the present invention a kind of for the bubble monitoring device in Portable blood purifying system, including ultrasonic bubble detector 4, signal processor 5, comparator 6, CPU processor 7 and alarm device 8;
Ultrasonic bubble detector 4 includes discharger 4-1 and reception device 4-2, discharger 4-1 are arranged on the both sides of blood catheter 3 with reception device 4-2;
Signal processor 5 includes interference signal processing module 5-1 and signal shaping module 5-2, and interference signal processing module 5-1 is connected with receiving device 4-2, eliminates for the interference signal docked in the receiving apparatus 4-2 ultrasonic pulse signal received。Owing to rocking of instrument can produce a lot of interference signals, also can affect the normal of sensor to be suitable for, therefore, also should be eliminated this type of interference signal, interference signal mostly generally is high frequency small-signal, is eliminated from hardware and software two aspect this interference signal is many。Hardware aspect, increases the devices such as active bandpass filiter circuit, Schmidt trigger, comparator in interference signal processing module 5-1 and eliminates interference signal。Software aspects, have employed digital filtering mode, and multiple repairing weld is averaged way。By the improvement of hardware and software two aspect, thus effectively eliminating the interference of interference signal。Signal shaping module 5-2 is connected with interference signal processing module 5-1, for the pulse signal after eliminating interference signal is carried out shaping the rectangular signal pulsewidth Tc of formation rule;
Comparator 6 is connected with signal processor 5, and CPU processor 7 is connected with comparator 6, alarm device 8 respectively。Comparator 6 is for comparing the threshold values of rectangular signal pulsewidth Tc Yu setting, and being provided with air pocket threshold values Tc1, bubble-free and micro bubble threshold values in comparator is Tc0;As Tc Tc1, it is judged that for air pocket, it is directly entered CPU processor 7 and starts alarm device 8;As Tc Tc0, it is judged that for bubble-free or trace minute bubbles, human body will not be produced injury, therefore need not report to the police, directly filter out;As Tc0 Tc Tc1, it is judged that for small size bubble, when this type bubble is accumulated to a certain degree, also human body can be damaged;Therefore, enter CPU processor 7 and carry out accumulation calculating by the accumulator in CPU processor 7, starting alarm device when cumulant per minute is more than setting value T。
What ultrasonic bubble detector 4 adopted is transmission ultrasonic wave detection method。In liquid proper flow and when not being mixed into bubble, the loss of sound wave is little, is sufficiently large in the amplitude receiving the ultrasonic pulse signal detected in device 4-2, signal pulsewidth width after the shaped process of signal;When blood occurs bubble, owing to sound wave major part is reflected, then relatively big in the amplitude decay when this bubble is by sensor detection faces receiving the device 4-2 ultrasonic pulse signal detected, after the shaped process of signal, signal pulsewidth narrows;Bubble is more big, and pulsewidth is more narrow。For making bubble monitoring device relatively reliable, bubble more than certain volume not only can be sent warning by the present invention, this volume bubbles below can be detected and estimate the volume of bubble simultaneously, and this volume is added up, once a dialysis procedure flows through when being not enough to cause the micro-bubble cumulative volume reported to the police to add up to exceed certain value of bubble monitoring device, also can report to the police, the potential safety hazard that prompting staff exists。
In actual use, air pocket threshold values Tc0 generally can set that as 20-100ul, it is adjustable that minute bubbles threshold values Tc1 is set as between 5-20ul, the accumulative threshold values T of minute bubbles is set as 1-3ml/ minute, by adjusting the setting of threshold values, the sensitivity of instrument can be changed, the practical situation according to patient, technician set the size of threshold values。
Embodiment 2: as shown in Figure 4, of the present invention a kind of for the bubble monitoring method in Portable blood purifying system, including:
Ultrasonic pulse signal A launched by step one, discharger, receives device and receives the ultrasonic pulse signal B through blood catheter;
Step 2, ultrasonic pulse signal B is carried out interference signal eliminate, and to eliminate interference after signal carry out shaping, the rectangular signal of formation rule and the pulsewidth of rectangular signal are Tc;
Step 3, the minute bubbles threshold values Tc0, the air pocket threshold values Tc1 that signal pulsewidth Tc and comparator are set by comparator are compared:
Tc Tc1, is directly entered CPU processor and starts alarm device;
Tc Tc0, directly filters out;
Tc0 Tc Tc1, enters CPU processor and carries out accumulation calculating, starting alarm device when cumulant per minute is more than setting value T。
Further, threshold values Tc1 is 20-100ul, Tc0 is 5-20ul, and Tc1 Tc0, setting value T are 1-3ml/ minute。
Further, starting alarm device and include starting sound and light alarm, blood presss from both sides Guan Bi, blood pump stall and heparin pump stall。
The reliability of the bubble monitoring device of the present invention obtains and is greatly reinforced, and especially when waving, vibrating battlefield, field, the difference with former air bubble sensor clearly, namely ensure that the promptly and accurately warning of bubble, effectively shields again various interference;Meanwhile, the present invention can pass through to adjust threshold values, changes the sensitivity of instrument。
Embodiment 3: the present invention detects test
The bubble monitoring device of the present invention is carried out vehicle-mounted dialysis test, carries out in the case where the vehicle is running。
Subjects: Canis familiaris L., body weight 23 kilograms
Test parameters: blood flow sets 300ml/ minute;Fluid infusion velocity sets 1 l/h;Dewatering speed sets 0.2 l/h;Dialysis time sets 5 hours。
In test, adopting original Ultrasonic Wave Air Detector, in 5 hours, Primordial Qi bubble sensor alarm is continuous, creates hundreds of times altogether and reports to the police, greatly disturbs the carrying out of dialysis。
Under identical condition, adopting assembly of the invention, the raw air pocket of common property is reported to the police 5 times, and accumulative bubble is reported to the police 3 times。
According to the result of the test obtained, carry out again many experiments。Experimental result all shows: the reliability of the ultrasonic bubble detector monitoring after improvement obtains and is greatly reinforced, especially when waving, vibrating battlefield, field, difference with former air bubble sensor clearly, namely ensure that the promptly and accurately warning of bubble, effectively shields again various interference。The present invention in Portable blood purifying system, can significantly improve the function of existing air bubble sensor。
These are only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations。All within the spirit and principles in the present invention, any amendment of making, equivalent replacement, improvement etc., should be included within protection scope of the present invention。

Claims (8)

1. the bubble monitoring device being used in Portable blood purifying system, it is characterised in that include ultrasonic bubble detector, signal processor, comparator, CPU processor and alarm device;
Described ultrasonic bubble detector includes discharger and receives device, and described discharger and reception device are arranged on the both sides of blood catheter;
Described signal processor is connected with receiving device, eliminates the rectangular signal pulsewidth Tc of also formation rule for the ultrasonic pulse signal received carries out interference signal;
Described comparator is connected with signal processor, and described CPU processor is connected with described comparator, alarm device respectively;Described comparator is for comparing the threshold values of rectangular signal pulsewidth Tc Yu setting, and being provided with air pocket threshold values Tc1, bubble-free and micro bubble threshold values in comparator is Tc0, as Tc Tc1, is directly entered CPU processor and starts alarm device;As Tc Tc0, directly filter out;As Tc0 Tc Tc1, enter CPU processor and carry out accumulation calculating, starting alarm device when cumulant per minute is more than setting value T。
2. as claimed in claim 1 for the bubble monitoring device in Portable blood purifying system, it is characterized in that, described signal processor includes interference signal processing module and signal shaping module, described interference signal processing module is connected with described reception device, and described signal shaping module is connected with described interference signal processing module。
3. as claimed in claim 2 for the bubble monitoring device in Portable blood purifying system, it is characterised in that described interference signal processing module includes one or more in active bandwidth-limited circuit, Schmidt trigger and comparator。
4. as claimed in claim 1 for the bubble monitoring device in Portable blood purifying system, it is characterised in that described CPU processor includes accumulator, calculate for the minute bubbles of Tc0 rectangular signal pulsewidth Tc Tc1 are carried out accumulation。
5. the monitoring method of the bubble monitoring device being used in Portable blood purifying system as claimed in claim 1, it is characterised in that including:
Ultrasonic pulse signal A launched by step one, discharger, receives device and receives the ultrasonic pulse signal B through blood catheter;
Step 2, ultrasonic pulse signal B is carried out interference signal eliminate, and to eliminate interference after signal carry out shaping, the rectangular signal of formation rule and the pulsewidth of rectangular signal are Tc;
Step 3, the minute bubbles threshold values Tc0, the air pocket threshold values Tc1 that signal pulsewidth Tc and comparator are set by comparator are compared:
Tc Tc1, is directly entered CPU processor and starts alarm device;
Tc Tc0, directly filters out;
Tc0 Tc Tc1, enters CPU processor and carries out accumulation calculating, starting alarm device when cumulant per minute is more than setting value T。
6. as claimed in claim 5 for the bubble monitoring method in Portable blood purifying system, it is characterised in that described threshold values Tc1 is 20-100ul, Tc0 is 5-20ul, and Tc1 Tc0。
7. as claimed in claim 5 for the bubble monitoring method in Portable blood purifying system, it is characterised in that described setting value T is 1-3ml/ minute。
8. as claimed in claim 5 for the bubble monitoring method in Portable blood purifying system, it is characterised in that described startup alarm device includes starting sound and light alarm, and blood presss from both sides Guan Bi, blood pump stall and heparin pump stall。
CN201610028600.8A 2016-01-15 2016-01-15 Portable blood purifying system bubble monitoring device and method Pending CN105688303A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108132299A (en) * 2018-03-06 2018-06-08 杭州森威传感科技有限公司 A kind of air bubble sensor and method for bubble in signal piping
JP2018201824A (en) * 2017-06-02 2018-12-27 株式会社ジェイ・エム・エス Ultrasound measurement apparatus and extracorporeal circulation apparatus
CN113457005A (en) * 2020-03-31 2021-10-01 上海微创心力医疗科技有限公司 Bubble detection method, electronic device, readable storage medium and blood pump system
CN113588181A (en) * 2021-07-23 2021-11-02 苏州浪潮智能科技有限公司 Negative pressure liquid cooling system air leakage detection system, method and device
CN113908383A (en) * 2021-12-14 2022-01-11 极限人工智能有限公司 Bubble detection method and device and triple tee system
CN113970618A (en) * 2020-07-23 2022-01-25 中天新兴材料有限公司 Slurry foamability evaluation system and slurry foamability evaluation method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487601A (en) * 1983-06-20 1984-12-11 Extracorporeal Medical Specialties, Inc. Bubble detector circuit with variable reference level
US4651555A (en) * 1984-09-11 1987-03-24 Introtek Corporation Apparatus for detecting discontinuities in a fluid stream
US5394732A (en) * 1993-09-10 1995-03-07 Cobe Laboratories, Inc. Method and apparatus for ultrasonic detection of air bubbles
CN101189509A (en) * 2005-06-03 2008-05-28 弗雷泽纽斯医疗保健德国有限公司 Method and device for monitoring a flow of liquid for the presence of air by means of ultrasound
CN103055364A (en) * 2013-01-21 2013-04-24 北京大德海纳医疗科技有限公司 Bubble monitoring device for portable blood purification system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487601A (en) * 1983-06-20 1984-12-11 Extracorporeal Medical Specialties, Inc. Bubble detector circuit with variable reference level
US4651555A (en) * 1984-09-11 1987-03-24 Introtek Corporation Apparatus for detecting discontinuities in a fluid stream
US5394732A (en) * 1993-09-10 1995-03-07 Cobe Laboratories, Inc. Method and apparatus for ultrasonic detection of air bubbles
CN101189509A (en) * 2005-06-03 2008-05-28 弗雷泽纽斯医疗保健德国有限公司 Method and device for monitoring a flow of liquid for the presence of air by means of ultrasound
CN103055364A (en) * 2013-01-21 2013-04-24 北京大德海纳医疗科技有限公司 Bubble monitoring device for portable blood purification system

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018201824A (en) * 2017-06-02 2018-12-27 株式会社ジェイ・エム・エス Ultrasound measurement apparatus and extracorporeal circulation apparatus
CN108132299A (en) * 2018-03-06 2018-06-08 杭州森威传感科技有限公司 A kind of air bubble sensor and method for bubble in signal piping
CN113457005A (en) * 2020-03-31 2021-10-01 上海微创心力医疗科技有限公司 Bubble detection method, electronic device, readable storage medium and blood pump system
CN113457005B (en) * 2020-03-31 2023-05-05 上海微创心力医疗科技有限公司 Bubble detection method, electronic device, readable storage medium, and blood pump system
CN113970618A (en) * 2020-07-23 2022-01-25 中天新兴材料有限公司 Slurry foamability evaluation system and slurry foamability evaluation method
CN113588181A (en) * 2021-07-23 2021-11-02 苏州浪潮智能科技有限公司 Negative pressure liquid cooling system air leakage detection system, method and device
CN113588181B (en) * 2021-07-23 2024-02-27 苏州浪潮智能科技有限公司 Negative pressure liquid cooling system air leakage detection system, method and device
CN113908383A (en) * 2021-12-14 2022-01-11 极限人工智能有限公司 Bubble detection method and device and triple tee system

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Application publication date: 20160622