CN105137058A - Immunoassay and biochemical detection system - Google Patents

Immunoassay and biochemical detection system Download PDF

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Publication number
CN105137058A
CN105137058A CN201510498063.9A CN201510498063A CN105137058A CN 105137058 A CN105137058 A CN 105137058A CN 201510498063 A CN201510498063 A CN 201510498063A CN 105137058 A CN105137058 A CN 105137058A
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module
main control
immunity
biochemical
wireless communication
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张树华
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The present invention relates to an immunological and biochemical detection system, which includes a mobile terminal, an immunological and biochemical detector and a cloud server; the mobile terminal is provided with a scan code module, a first main control module, a first wireless communication module and a display module; the immunological and biochemical detector includes a second main control module, a second wireless communication module, a detection module, a test paper box and an image acquisition module, a two-dimensional code is arranged on the test paper box; the mobile terminal scans the two-dimensional code on the test paper box to get test paper information, and sends a corresponding biochemical substance detection control signal to the immunological and biochemical detector; the immunological and biochemical detector tests a sample on test paper in the test paper box, and sends detected test paper image information to the cloud server; and the cloud server analyzes the image information to obtain the content of a biochemical substance, and sends, by network, the analyzed content of the biochemical substance to the mobile terminal for displaying. The beneficial effects are that: the immunological and biochemical detection system has the ability to intelligently network, and is highly integrated and easy to use.

Description

A kind of immunity and biochemical detection system
Technical field
The invention belongs to biochemistry detection field, be specifically related to a kind of immunity and biochemical detection system.
Background technology
Biochemical Analyzer is a kind of instrument for determination and analysis life chemistry material, its can clinically to the diagnosis of disease, treatment and more after and health status information foundation is provided, it has, and measuring speed is fast, accuracy is high and consume the advantages such as amount of reagent is little.But, the employing colloidal gold method that Biochemical Analyzer of the prior art has detects biological, some employing dry chemical methods detect biological, the employing fluorescent technique also had detects biological, also do not have the integrated above-mentioned three kinds of detection methods of a Biochemical Analyzer at present, therefore the functional integration of Biochemical Analyzer of the prior art is low.In addition, existing Biochemical Analyzer needs professional to operate, and is not suitable for family and uses, can not popularize; And existing Biochemical Analyzer can not be networked, there is no the support of background data base.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides a kind of can the immunity high and easy to use of intelligent networking, integrated level and biochemical detection system.
The technical solution adopted in the present invention is: a kind of immunity and biochemical detection system comprise mobile terminal, immunity and bio-chemical detector and Cloud Server; Barcode scanning module, the first main control module, the first wireless communication module and display module are set in described mobile terminal; Described immunity and bio-chemical detector comprise the second main control module, the second wireless communication module, detection module, paper box and image capture module, and described paper box arranges Quick Response Code; Described Quick Response Code on paper box described in described barcode scanning module scans also transfers to described first main control module, and described first main control module obtains test paper information according to the described Quick Response Code received; Described first main control module sends the detection control signal of corresponding biological to described immunity and bio-chemical detector by described first wireless communication module according to test paper information; Described second main control module receives the detection control signal of biological by described second wireless communication module, and control described detection module the sample on test paper in described paper box is detected, test paper obtains the colouring information after specimen reaction, described image capture module gathers the image information on sample, and the image information collected is transferred to described second main control module, image information is sent to described Cloud Server by described second wireless communication module by described second main control module; Described Cloud Server adopts colourimetry to analyze the image information received, and obtains the content of certain biological; The content analyzing the biological obtained is sent to described mobile terminal by network by described Cloud Server; Described first main control module receives the content of biological by described first wireless communication module, and transfers to described display module and show.
Preferably, described first wireless communication module and the second wireless communication module all adopt WiFi module or bluetooth module.
Further, be also provided with cloud storage in described immunity and biochemical detection system, described cloud storage is connected with described Cloud Server, the standard content of the title of the biological obtained for inventory analysis, content information and various biological.
Further, described detection module comprises collaurum detection module, dry chemical method detection module and fluoroscopic examination module; Described main control module selects different described detection modules according to test paper information, and the described detection module controlling to select detects corresponding biological.
Further, described paper box comprises some test strips and a box body, described test strips is arranged in described box body, the end face of described box body one end is offered successively application of sample window and colour developing window, by described application of sample window, sample is dripped in described test strips, by described colour developing window display sample reacted color in test strips; Described Quick Response Code is arranged on the end face of the described box body other end, comprises test substances type and the date of manufacture information of described test strips in described Quick Response Code.
Further, the height of described application of sample window is more than or equal to the height of described colour developing window.
Further, described image capture module comprises optical lens, light source and camera module; Described optical lens is arranged on above described paper box, for increasing light path light path and the imaging area and the pixel count that increase image; Described light source is arranged on the side of described optical lens, for providing independent and having the light of specific wavelength; Described camera module is arranged on above optical lens, for taking the image information after test paper occurs biochemical reaction, and image information is transferred to described second main control module, send to described mobile terminal by described second wireless communication module after described second main control module converts the image information received to digital signal.
Further, described light source is made up of LED lamp bead and optical filter.
Further, described camera module adopts the varifocal camera of microspur, and the pixel count of the varifocal camera of described microspur is more than or equal to 2,000,000 pixels.
Owing to adopting above technical scheme, beneficial effect of the present invention is: the present invention, by arranging wireless communication module, can realize mobile terminal, immunity and the networking between bio-chemical detector and Cloud Server.Colloidal gold method, dry chemical method and fluorescence detection three kinds of measuring abilities, by arranging collaurum detection module, dry chemical method detection module and fluoroscopic examination module, integrate, have the advantage that integrated level is high by the present invention.The present invention sends the detection control signal of corresponding biological by moving to terminal to immunity and bio-chemical detector, and the present invention has easy and simple to handle, is convenient to the advantage promoted the use of.In addition, the analysis that the present invention disposablely can also complete many biologicals detects, and has conveniently advantage.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the present invention's immunity and biochemical detection system;
Fig. 2 is the structural representation of paper box in the present invention's immunity and biochemical detection system.
In figure: 1, mobile terminal; 2, immunity and bio-chemical detector; 3, Cloud Server; 4, cloud storage; 11, barcode scanning module; 12, the first main control module; 13, the first wireless communication module; 14, display module; 21, the second main control module; 22, the second wireless communication module; 23, detection module; 24, paper box; 25, image capture module; 26, Quick Response Code; 241, box body; 242, application of sample window; 243, develop the color window.
Embodiment
As shown in Figure 1, the invention provides a kind of immunity and biochemical detection system, it comprises mobile terminal 1, immunity and bio-chemical detector 2 and Cloud Server 3.Wherein, barcode scanning module 11, first main control module 12, first wireless communication module 13 and display module 14 are set in mobile terminal 1.Immunity and bio-chemical detector 2 comprise the second main control module 21, second wireless communication module 22, detection module 23, paper box 24 and image capture module 25, paper box 24 are arranged Quick Response Code 26.
Barcode scanning module 11 scans the Quick Response Code 26 on paper box 24 and transfers to the first main control module 12, first main control module 12 and obtains the test paper information such as test substances type, date of manufacture according to the Quick Response Code 26 received.First main control module 12 sends the detection control signal of corresponding biological to immunity and bio-chemical detector 2 by the first wireless communication module 13 according to test paper information.
Second main control module 21 receives the detection control signal of biological by the second wireless communication module 22, and the sample controlled in detection module 23 pairs of paper boxes 24 on test paper detects, test paper obtains the colouring information after specimen reaction, image capture module 25 gathers the image information on sample, and the image information collected is transferred to after the second main control module 21, second main control module 21 processes the figure line information received and send to Cloud Server 3 by the second wireless communication module 22.Further, the first wireless communication module 13 and the second wireless communication module 22 all adopt WiFi module or bluetooth module.
Cloud Server 3 adopts colourimetry to analyze the image information received, and its detailed process is: Cloud Server 3 extracts the gray-scale value in image information, and is compared by the standard color comparison card of gray-scale value and test paper, obtains the content of certain biological.The content analyzing the biological obtained is sent to mobile terminal 1 by network by Cloud Server 3.
First main control module 12 receives the content of biological by the first wireless communication module 13, and the content of the biological received is transferred to display module 14 shows.
In a preferred embodiment, cloud storage 4 is also provided with in the present invention's immunity and biochemical detection system, cloud storage 4 is connected with Cloud Server 3, the information such as the standard content of the title of the biological obtained for inventory analysis, content and various biological, be convenient to user transfers the biological stored in cloud storage 4 in real time historical information by mobile terminal 1, also be convenient to Cloud Server judge analyzing the content of certain biological obtained according to the standard content information of various biological, and provide conductive suggestion for user.In addition, utilize mobile terminal 1, Cloud Server 3 and cloud storage 4, between each user, internet intercommunion platform can also be set up.
In a preferred embodiment, detection module 23 comprises collaurum detection module, dry chemical method detection module and fluoroscopic examination module.Main control module selects different detection modules 23 according to test paper information, and the detection module 23 controlling to select detects corresponding biological.
In a preferred embodiment, as shown in Figure 2, paper box 24 comprises some test strips and a box body 241, wherein, test strips is arranged in box body 241, the end face of box body 241 one end is offered successively application of sample window 242 and colour developing window 243, by application of sample window 242, sample is dripped in test strips, show sample reacted color on test paper by colour developing window 243; Quick Response Code 26 is arranged on the end face of box body 241 other end, comprises the information such as test substances type and date of manufacture of test strips in Quick Response Code 26.Further, the height of application of sample window 242 is more than or equal to the height of colour developing window 243.When the height of application of sample window 242 is greater than the height of colour developing window 243, the sample dropped in test strips utilizes the potential difference of liquid to be diffused into the position of colour developing window 243 uniformly, thus can reduce the error of biological detection.The present invention, by arranging some test strips, disposablely can realize the detection of multiple biological, have conveniently feature.
In a preferred embodiment, image capture module 25 comprises optical lens, light source and camera module.Wherein, optical lens is arranged on above paper box 26, for increasing light path light path and the imaging area and the pixel count that increase image.Light source is arranged on the side of optical lens, for providing independent and having the light of specific wavelength.Camera module is arranged on above optical lens, for taking the image information after test paper occurs biochemical reaction, and image information is transferred to after the second main control module 21, second main control module 21 converts the image information received to digital signal and send to mobile terminal 1 by the second wireless communication module 22.Further, light source is made up of LED lamp bead and optical filter.Camera module adopts the varifocal camera of microspur, and the pixel count of the varifocal camera of microspur is more than or equal to 2,000,000 pixels.
The present invention is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present invention; no matter but any change is done in its shape or structure; every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.

Claims (9)

1. immunity and a biochemical detection system, is characterized in that: it comprises mobile terminal, immunity and bio-chemical detector and Cloud Server; Barcode scanning module, the first main control module, the first wireless communication module and display module are set in described mobile terminal; Described immunity and bio-chemical detector comprise the second main control module, the second wireless communication module, detection module, paper box and image capture module, and described paper box arranges Quick Response Code;
Described Quick Response Code on paper box described in described barcode scanning module scans also transfers to described first main control module, and described first main control module obtains test paper information according to the described Quick Response Code received; Described first main control module sends the detection control signal of corresponding biological to described immunity and bio-chemical detector by described first wireless communication module according to test paper information;
Described second main control module receives the detection control signal of biological by described second wireless communication module, and control described detection module the sample on test paper in described paper box is detected, test paper obtains the colouring information after specimen reaction, described image capture module gathers the image information on sample, and the image information collected is transferred to described second main control module, image information is sent to described Cloud Server by described second wireless communication module by described second main control module;
Described Cloud Server adopts colourimetry to analyze the image information received, and obtains the content of certain biological; The content analyzing the biological obtained is sent to described mobile terminal by network by described Cloud Server;
Described first main control module receives the content of biological by described first wireless communication module, and transfers to described display module and show.
2. a kind of immunity as claimed in claim 1 and biochemical detection system, is characterized in that: described first wireless communication module and the second wireless communication module all adopt WiFi module or bluetooth module.
3. a kind of immunity as claimed in claim 1 and biochemical detection system, it is characterized in that: in described immunity and biochemical detection system, be also provided with cloud storage, described cloud storage is connected with described Cloud Server, the standard content information of the title of the biological obtained for inventory analysis, content information and various biological.
4. the one immunity as described in claim 1 or 2 or 3 and biochemical detection system, is characterized in that: described detection module comprises collaurum detection module, dry chemical method detection module and fluoroscopic examination module; Described main control module selects different described detection modules according to test paper information, and the described detection module controlling to select detects corresponding biological.
5. the one immunity as described in claim 1 or 2 or 3 and biochemical detection system, it is characterized in that: described paper box comprises some test strips and a box body, described test strips is arranged in described box body, the end face of described box body one end is offered successively application of sample window and colour developing window, by described application of sample window, sample is dripped in described test strips, by described colour developing window display sample reacted color in test strips; Described Quick Response Code is arranged on the end face of the described box body other end, comprises test substances type and the date of manufacture information of described test strips in described Quick Response Code.
6. a kind of immunity as claimed in claim 5 and biochemical detection system, is characterized in that: the height of described application of sample window is more than or equal to the height of described colour developing window.
7. the one immunity as described in claim 1 or 2 or 3 and biochemical detection system, is characterized in that: described image capture module comprises optical lens, light source and camera module; Described optical lens is arranged on above described paper box, for increasing light path light path and the imaging area and the pixel count that increase image; Described light source is arranged on the side of described optical lens, for providing independent and having the light of specific wavelength; Described camera module is arranged on above optical lens, for taking the image information after test paper occurs biochemical reaction, and image information is transferred to described second main control module, send to described mobile terminal by described second wireless communication module after described second main control module converts the image information received to digital signal.
8. a kind of immunity as claimed in claim 7 and biochemical detection system, is characterized in that: described light source is made up of LED lamp bead and optical filter.
9. a kind of immunity as claimed in claim 7 and biochemical detection system, is characterized in that: described camera module adopts the varifocal camera of microspur, and the pixel count of the varifocal camera of described microspur is more than or equal to 2,000,000 pixels.
CN201510498063.9A 2015-08-13 2015-08-13 Immunoassay and biochemical detection system Pending CN105137058A (en)

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106226291A (en) * 2016-01-26 2016-12-14 江苏戴格诺思生物技术有限公司 A kind of method of mobile terminal quantitative analysis dry chemistry detectable
CN106680478A (en) * 2017-02-24 2017-05-17 成都微瑞生物科技有限公司 Gold labeled detection system and method based on cloud platform
WO2018082257A1 (en) * 2016-11-05 2018-05-11 深圳市前海安测信息技术有限公司 Biomarker detecting system and method based on colloidal gold test strip
CN108333153A (en) * 2017-01-20 2018-07-27 上海溯源生物技术有限公司 Project testing system and project testing method
CN108627482A (en) * 2017-03-20 2018-10-09 上海溯源生物技术有限公司 Fluorescence detection device and its fluorimetric analysis method based on mobile terminal
CN108922584A (en) * 2018-08-28 2018-11-30 深圳先进技术研究院 Convenient and quick detection device and its application
CN109270264A (en) * 2018-11-29 2019-01-25 福州大学 A kind of immune and bio-chemical detector control system and its method
CN109587337A (en) * 2018-12-14 2019-04-05 江苏科技大学 A kind of method and smart phone of quick detection mycotoxin
CN109959780A (en) * 2019-04-28 2019-07-02 深圳市赛泰诺生物技术有限公司 A kind of minimal feeding device, method and smart phone
CN110161224A (en) * 2019-04-29 2019-08-23 成都莱孚科技有限责任公司 A kind of pet disease detecting system based on cloud data processing
CN110456050A (en) * 2019-07-11 2019-11-15 台州云海医疗科技有限公司 Portable intelligent digitizes helminth in-vitro diagnosis instrument
CN111624331A (en) * 2020-05-22 2020-09-04 军事科学院系统工程研究院卫勤保障技术研究所 Multichannel synchronous fluorescence immunochromatography detection system
CN111830020A (en) * 2020-07-22 2020-10-27 中国人民解放军总医院 Medical test paper detecting system
CN112630173A (en) * 2020-12-04 2021-04-09 闪优智谱(厦门)检测科技有限公司 Chemical composition analysis system
CN113156109A (en) * 2021-03-16 2021-07-23 广州埃克森生物科技有限公司 Multifunctional immune quantitative analyzer and implementation method thereof

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106226291A (en) * 2016-01-26 2016-12-14 江苏戴格诺思生物技术有限公司 A kind of method of mobile terminal quantitative analysis dry chemistry detectable
WO2018082257A1 (en) * 2016-11-05 2018-05-11 深圳市前海安测信息技术有限公司 Biomarker detecting system and method based on colloidal gold test strip
CN108333153A (en) * 2017-01-20 2018-07-27 上海溯源生物技术有限公司 Project testing system and project testing method
CN106680478A (en) * 2017-02-24 2017-05-17 成都微瑞生物科技有限公司 Gold labeled detection system and method based on cloud platform
CN108627482A (en) * 2017-03-20 2018-10-09 上海溯源生物技术有限公司 Fluorescence detection device and its fluorimetric analysis method based on mobile terminal
CN108922584A (en) * 2018-08-28 2018-11-30 深圳先进技术研究院 Convenient and quick detection device and its application
CN109270264A (en) * 2018-11-29 2019-01-25 福州大学 A kind of immune and bio-chemical detector control system and its method
CN109587337A (en) * 2018-12-14 2019-04-05 江苏科技大学 A kind of method and smart phone of quick detection mycotoxin
CN109959780A (en) * 2019-04-28 2019-07-02 深圳市赛泰诺生物技术有限公司 A kind of minimal feeding device, method and smart phone
CN110161224A (en) * 2019-04-29 2019-08-23 成都莱孚科技有限责任公司 A kind of pet disease detecting system based on cloud data processing
CN110456050A (en) * 2019-07-11 2019-11-15 台州云海医疗科技有限公司 Portable intelligent digitizes helminth in-vitro diagnosis instrument
CN110456050B (en) * 2019-07-11 2022-07-19 台州云海医疗科技有限公司 Portable intelligent digital parasite in vitro diagnostic instrument
CN111624331A (en) * 2020-05-22 2020-09-04 军事科学院系统工程研究院卫勤保障技术研究所 Multichannel synchronous fluorescence immunochromatography detection system
CN111830020A (en) * 2020-07-22 2020-10-27 中国人民解放军总医院 Medical test paper detecting system
CN112630173A (en) * 2020-12-04 2021-04-09 闪优智谱(厦门)检测科技有限公司 Chemical composition analysis system
CN113156109A (en) * 2021-03-16 2021-07-23 广州埃克森生物科技有限公司 Multifunctional immune quantitative analyzer and implementation method thereof

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Application publication date: 20151209