CN104083608A - Traditional Chinese medicine preparation for treating schizophrenia - Google Patents
Traditional Chinese medicine preparation for treating schizophrenia Download PDFInfo
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- CN104083608A CN104083608A CN201410254939.0A CN201410254939A CN104083608A CN 104083608 A CN104083608 A CN 104083608A CN 201410254939 A CN201410254939 A CN 201410254939A CN 104083608 A CN104083608 A CN 104083608A
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Abstract
A traditional Chinese medicine preparation for treating schizophrenia. Raw materials of the preparation includes: 30 parts of radix rehmanniae, 20 parts of white paeony root, 20 parts of radix ophiopogonis, 20 parts of dendrobe, 20 parts of semen ziziphi spinosae, 18 parts of calamus, 12 parts of anemarrhenae, 30 parts of caulis akebiae, 18 parts of rhubarb, 60 parts of gypsum, 12 parts of poria cocos, 12 parts of pericarpium citri reticulatae and 12 parts of polygala tenuifolia. A preparation method of the traditional Chinese medicine preparation includes following steps: weighing 30 parts of radix rehmanniae, 20 parts of white paeony root, 20 parts of radix ophiopogonis, 20 parts of dendrobe, 20 parts of semen ziziphi spinosae, 18 parts of calamus, 12 parts of anemarrhenae, 30 parts of caulis akebiae, 18 parts of rhubarb, 60 parts of gypsum, 12 parts of poria cocos, 12 parts of pericarpium citri reticulatae and 12 parts of polygala tenuifolia as the raw materials, respectively preparing each raw material into decocting pieces, carrying out a steaming and boiling process to the raw materials in a pressure cooker for 30-60 min for sterilization, drying the raw materials in air to obtain sterilized raw materials, and preparing the sterilized raw materials into the traditional Chinese medicine preparation. The traditional Chinese medicine preparation has effects of tranquilizing and allaying excitement, activating blood and quieting heart, and nourishing blood and yin. The traditional Chinese medicine preparation is used for treating schizophrenia.
Description
Technical field
The present invention relates to field of traditional Chinese; Be specifically related to one and treat schizoid Chinese medicine preparation.
Background technology
Schizophrenia is one group of major psychosis that the cause of disease is not bright, the how slow or subacute onset person between twenty and fifty, often show as clinically the different syndrome of symptom, relate to the inharmonious of many-sided obstacles such as sensory perception, thinking, emotion and behavior and ergasia.The general Clear consciousness of patient, intelligent normal, but some patients were there will be the infringement of cognitive function in lysis.The course of disease is generally delayed, and is repeatedly and shows effect, increases the weight of or worsen, and decline and mental handicap finally appear in some patients were, but some patients can keep recovery from illness or the state that is almost recovered after treatment.The clinical syndrome that schizophrenia is made up of one group of syndrome, it is multifactorial disease.Although at present still not bery clear and definite to the understanding of its cause of disease, the effect of the susceptible quality of individual mind and the undesirable element of the outside social environment generation development to disease is known together by everybody.Be the generation that susceptible quality or outside undesirable element all may cause by inherent biological factor combined effect disease, the factor of different its morbidities of patient may be with outbalance in a certain respect.The other medicines for the treatment of this disease in prior art exist therapeutic effect not obvious, the technological deficiency that side effect is large.
Summary of the invention
The object of the present invention is to provide a kind ofly there is tranquillizing and allaying excitement, the Chinese medicine preparation of the mind calming of invigorating blood circulation, nourishing the blood and yin effect, be used for the treatment of schizophrenia.
Technical scheme of the present invention: the raw material of Chinese medicine preparation of the present invention and each component consumption thereof are groped in a large number to sum up through inventor and drawn, each component amount all has good effect within the scope of this: 30 parts, the Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Ophiopogonis, 20 parts of Herba Dendrobiis, 20 parts of Semen Ziziphi Spinosaes, 18 parts of Rhizoma Acori Gramineis, 12 parts of the Rhizoma Anemarrhenaes, 30 parts of Caulis Akebiaes, 18 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 12 parts, Poria, 12 parts of Pericarpium Citri Reticulataes, 12 parts of Radix Polygalaes.
For reaching tranquillizing and allaying excitement, the mind calming of invigorating blood circulation, nourishing the blood and yin effect, the present invention selects 12 parts, 30 parts, the Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Ophiopogonis, 20 parts of Herba Dendrobiis, 20 parts of Semen Ziziphi Spinosaes, 18 parts of Rhizoma Acori Gramineis, 12 parts of the Rhizoma Anemarrhenaes, 30 parts of Caulis Akebiaes, 18 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 12 parts, Poria, 12 parts of Pericarpium Citri Reticulataes, Radix Polygalae to combine, by these drug regimens, make each efficacy of drugs produce synergism, thereby can effectively treat schizophrenia.In the raw materials of traditional Chinese medicinal materials of choosing, its effect and pharmacological action respectively:
The Radix Rehmanniae: be also Radix Rehmanniae, the fresh or dry tuber of Scrophulariaceae herbaceos perennial Radix Rehmanniae Rehmannia glutinosa Libosch..Main product is in China Henan, Hebei, the Inner Mongol and northeast.There is cultivation most areas.Excavate autumn, using fresh herb or dry sliced raw using.Radix Rehmanniae Preparata is that Radix Rehmanniae is mixed steaming to inside and outside darkish complexion, glossy through adding yellow wine, or directly steaming to black profit forms.Cutting sheet uses.Effect that Radix Rehmanniae has clearing away heat and cooling blood, tonifying YIN to promote the production of body fluid.
The Radix Paeoniae Alba: the Radix Paeoniae Alba is the famous traditional parts of generic medicinal plants of China, and applicating history is long, Radix Paeoniae begins to be loaded in Eastern Han Dynasty's Shennong's Herbal, classifies middle product as, and note has " main pathogen, except arthralgia due to stagnation of blood, broken heavily fortified point is long-pending, cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating ".The Radix Paeoniae Alba is cool in nature, and bitter in the mouth acid, is slightly cold, and has the easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing is received the effect such as antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, is with inferior disease.
Radix Ophiopogonis: [effect] nourishing YIN and moistening the lung; Reinforcing stomach reg fluid; Relieving restlessness clears away heart-fire.Dryness of the lung dry cough, spits blood, spitting of blood, and consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, quenches one's thirst, calentura Tianjin wound, dry mouth and throat, constipation.[curing mainly]: dryness of the lung dry cough; Spit blood; Spitting of blood; Consumptive lung disease; Lung abscess; Deficiency of YIN chronic cough; Tianjin wound is thirsty; Quench one's thirst; Calentura Tianjin wound; Vexed insomnia; Have sore throat; Dryness of the intestine constipation; Heat in blood is told nosebleed." book on Chinese herbal medicine converges and says ": Radix Ophiopogonis, the medicine of clearing away heart-fire and moistening the lung also.Main deficiency of heart-QI, palpitation with fear palpitation with a distress feeling, forgetful in a trance, spirit fall; Or the lung-heat dryness of the lung, cough sound running fire, consumptive lung disease leaf scorch, the dyspnea due to deficiency of losing heart, in fire volt lung, spitting of blood hemoptysis; Or asthenia exopathogenic heat, body fluid is dry few; Or taste are dry dries up, constipation due to insufficiency dyschezia; All the strongly fragrant card of cardiopulmonary kidney spleen unit asthenic fire is also for this.But sweet in the mouth gas is flat, energy lung benefiting gold, bitter in the mouth is cold in nature, can fall heart-fire, and body profit matter is mended, and can support medulla renis, and the merit of specially controlling strain deficiency-heat is in the majority.
Herba Dendrobii: all kinds of Herba Dendrobii goods.Comprise: Herba Dendrobii, Tongpi Fendou, HERBA DENDROBII etc.Herba Dendrobii is one of orchid of recording the earliest during China's ancient Chinese prose is offered.Its nature and flavor: sweet light micro-salty.Property belong to clear and rich, have benefit in clear, invigorating middle warmer has clearly.Function cures mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.
Semen Ziziphi Spinosae: sweet in the mouth, acid, property is flat.Can nourish conscience, calm the nerves, arresting sweating.There are calmness, hypnosis, analgesia, anticonvulsant action; There is certain hypotensive effect; There is to excitation in uterus.
Rhizoma Acori Graminei (formal name used at school: Acorus calamus), the aquatic herbaceous plant of a kind of Araeceae section, savory.Marsh, limes marginis, lakeside are born in Rhizoma Acori Graminei happiness, and whole temperate zone can be found it substantially, and also there is distribution all parts of the country.Rhizoma Acori Graminei can be extracted aromatic oil.The custom of Dragon Boat Festival handlebar Folium Acori graminei together with Chinese mugwort bundle.Nature and flavor: warm in nature, acrid in the mouth, hardship.Purposes: can dirtyly have one's ideas straightened out for warding off, a surname's gas is by expectorant, removing toxic substances, parasite killing.Control demented, infantile convulsion, coma due to phlegm syncope, anemofrigid-damp arthralgia, mouthful fulminant dysentery of keeping silent, external application carbuncle scabies.Have one's ideas straightened out, reduce phlegm, stomach invigorating., chronic bronchitis vexed for epilepsy, expectorant febrile convulsion, breast abdominal distention.
The Rhizoma Anemarrhenae: belong to gunpowder under heat clearing away, cure mainly: epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, the stranguria with turbid discharge of quenching one's thirst.Effect: clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Caulis Akebiae: the dry rattan of plants of Lardizabalaceae Caulis Akebiae Akebia quinata (Thunb.) Decne., threeleaf akebia Akebia trifoliate (Thunb.) Koidz. or Caulis Akebiae Akebia trifoliate (Thunb.) Koidz.var.australis (Diels) Rehd..Nature and flavor hardship, cool.Pathogenic fire purging row water.Promoting blood circulation.Cure mainly hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.Interior without damp and hot, body fluid deficiency, a little less than gas, essence is sliding, urinates frequently and is not taken by pregnant women.[function]: clearing away heart-fire, diuresis, the stimulating milk secretion of stimulating the menstrual flow.For irritable feverish sensation in the chest, sore throat pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain, amenorrhea breast is few.[attending effectiveness]: clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Main red urine is red; Stranguria with turbid discharge; Edema; Irritable feverish sensation in the chest; Larynx larynx pain; Aphtha of the mouth and tongue; Rheumatic arthralgia; Galactostasis; Amenorrhea; Dysmenorrhea.
Radix Et Rhizoma Rhei: the dry root and rhizome of polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim.ex Balf. or Rheum officinale Rheum officinale Baill..Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Cure mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria.Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.
Gypsum Fibrosum: Gypsum Fibrosum is calcium sulphate dihydrate (Ca (SO4) 2H2O), claims again dihydrate gypsum, water stone cream or soft gypsum, theoretical composition CaO32.6%, SO346.5%, H2O+20.9%, monoclinic system, crystal is tabular, conventionally be compact massive or fibrous, white or grey, red, brown, glass or silky luster, mohs hardness is 2, cleavage is parallel, and { 010} is complete, density 2.3g/cm3; [curing mainly] apoplexy cold and heat, heart subinverse gas is frightened to be breathed heavily, and xerostomia scorching tongue, can not cease, hardness and fullness in the abdomen pain, evil removing ghost, puerperium incised wound.Except seasonal epidemic pathogens headache fever of the body, the large heat of three warmers, skin heat, stagnation of QI in the intestines and stomach, expelling pathogenic factors from muscles by diaphoresis, the restlessness accompanied by ascending of QI of only quenching one's thirst, the sudden and violent gas of abdominal distention, the pharynx heat of panting, also can do bath soup.Cure the wound cold headache as split.Simmer tea with Herba Alii fistulosi, the pain of decaptitating.Control day row fanatic, wind syndrome of head revolves, and stimulating milk secretion is wiped tooth benefit tooth.Except gastric heat lung-heat, loose YIN pathogen, slow spleen QI invigorating.Only Yangming Channel headache, fever with chills, day food in one's mouth hectic fever, drinking a large amount of water due to extreme thirst, heatstroke hectic fever, has a toothache.
Poria: the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.Ancients claim that Poria is " god medicine " at 4 o'clock, because its effect is very extensive, regardless of the four seasons, by it and various compatibility of drugs, no matter cold, temperature, wind, all diseases that wets can be brought into play its unique effects.Poria sweet in the mouth, light, property are flat, be used as medicine there is promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.Poria slightly sweet flavor is flat, enters the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The diuretic of Poria, reaches by strong activating the spleen pulmonary function, different from the Chinese medicine of other direct diuretic.
Pericarpium Citri Reticulatae: Pericarpium Citri Reticulatae is containing hesperidin approximately 8.4%, and the about 0.15%. of Nobiletin (nobiletin) is separately containing Neosynephrine (oxedrine) 0.28%-2.54%.[attending effectiveness]: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, dyspepsia.Abdominal distention uncomfortable in chest, indigestion and loss of appetite loose stool in turbid damp resistance.Phlegm-damp is stopped up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Radix Polygalae: the dry root of milk wort Radix Polygalae Polygala tenuifolia Willd. or ovum leaf Radix Polygalae Polygala sibirica L..Warm in nature, bitter in the mouth, pungent, the function of there is the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subsiding a swelling, the insomnia and dreamful sleep causing for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
For Da Gengjia result of use, the present invention also provides the preparation method of this Chinese medicine preparation; Its preparation method: take 12 parts, 30 parts, the raw material Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Ophiopogonis, 20 parts of Herba Dendrobiis, 20 parts of Semen Ziziphi Spinosaes, 18 parts of Rhizoma Acori Gramineis, 12 parts of the Rhizoma Anemarrhenaes, 30 parts of Caulis Akebiaes, 18 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 12 parts, Poria, 12 parts of Pericarpium Citri Reticulataes, Radix Polygalae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation and get final product.
Chinese medicine for outer use of the present invention has tranquillizing and allaying excitement, the mind calming of invigorating blood circulation, nourishing the blood and yin effect, is used for the treatment of schizophrenia.So far, still do not find report and the application about Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the Chinese medicine preparation that has better curative effect, thereby has completed the present invention.
Specific implementation method
Treatment schizophrenia of the present invention, its raw material is: 30 parts, the Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Ophiopogonis, 20 parts of Herba Dendrobiis, 20 parts of Semen Ziziphi Spinosaes, 18 parts of Rhizoma Acori Gramineis, 12 parts of the Rhizoma Anemarrhenaes, 30 parts of Caulis Akebiaes, 18 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 12 parts, Poria, 12 parts of Pericarpium Citri Reticulataes, 12 parts of Radix Polygalaes.
Its preparation method: take 12 parts, 30 parts, the raw material Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Ophiopogonis, 20 parts of Herba Dendrobiis, 20 parts of Semen Ziziphi Spinosaes, 18 parts of Rhizoma Acori Gramineis, 12 parts of the Rhizoma Anemarrhenaes, 30 parts of Caulis Akebiaes, 18 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 12 parts, Poria, 12 parts of Pericarpium Citri Reticulataes, Radix Polygalae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation and get final product.
Claims (2)
1. the schizoid Chinese medicine preparation for the treatment of, is characterized in that: its raw material is; 30 parts, the Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Ophiopogonis, 20 parts of Herba Dendrobiis, 20 parts of Semen Ziziphi Spinosaes, 18 parts of Rhizoma Acori Gramineis, 12 parts of the Rhizoma Anemarrhenaes, 30 parts of Caulis Akebiaes, 18 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 12 parts, Poria, 12 parts of Pericarpium Citri Reticulataes, 12 parts of Radix Polygalaes.
2. according to the schizoid Chinese medicine preparation for the treatment of claimed in claim 1, it is characterized in that: its preparation method: take 12 parts, 30 parts, the raw material Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Ophiopogonis, 20 parts of Herba Dendrobiis, 20 parts of Semen Ziziphi Spinosaes, 18 parts of Rhizoma Acori Gramineis, 12 parts of the Rhizoma Anemarrhenaes, 30 parts of Caulis Akebiaes, 18 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 12 parts, Poria, 12 parts of Pericarpium Citri Reticulataes, Radix Polygalae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation and get final product.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104667200A (en) * | 2015-03-29 | 2015-06-03 | 孙辉 | Pharmaceutical composition for treating schizophrenia |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104667200A (en) * | 2015-03-29 | 2015-06-03 | 孙辉 | Pharmaceutical composition for treating schizophrenia |
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Application publication date: 20141008 |