Summary of the invention
The object of this invention is to provide a kind of preparation of effective treatment diabetes, to be inventor go out according to secret prescription handed down in the family from generation to generation and the clinical experience of decades and practice summary technical scheme of the present invention, its medicine has prescription " science ", the advantages such as refine " intricacies " and curative effect " uniqueness ".
The property of medicine and the pharmacology of Chinese herbal medicine selected by the present invention are respectively:
Radix Pseudostellariae: sweet, micro-hardship is flat.Return spleen, lung meridian.
Function cures mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Poria: sweet, light is flat.GUIXIN, lung, spleen, kidney channel.
Function cures mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Asparagi: sweetness and bitterness, cold.Enter lung, kidney channel.
Function cures mainly: YIN nourishing, moisturizes, lung heat clearing, pathogenic fire reducing.Control fever due to yin deficiency, cough is spitted blood, and consumptive lung disease, lung abscess, laryngopharynx swelling and pain, quenches one's thirst, constipation.
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.
Function cures mainly: spleen reinforcing nourishing the stomach, and promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Fructus Lycii: sweet, property is put down.Return Liver Channel, kidney channel, lung meridian.
Function cures mainly: caused by liver and kidney deficiency; Have a dizzy spell; Visual one clear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease.
Fructus Mume: sour, puckery is flat.Return liver, spleen, lung, large intestine channel.
Function cures mainly: astringe the lung, and astringing intestine to stop diarrhea promotes the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.
Endothelium Corneum Gigeriae Galli: sweet is flat.Return spleen, stomach, small intestinal, urinary bladder channel.
Function cures mainly: invigorating the stomach and promoting digestion, arresting seminal emission.Do not disappear for food stagnation, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.
Fructus Mori: sweet, sour, cold.GUIXIN, liver, kidney channel.
Function cures mainly: YIN nourishing of enriching blood, and promotes the production of body fluid and moisturizes.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.Tonifying liver, kidney tonifying, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows liquid.Control hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.
Semen Litchi: sweet, micro-hardship, temperature.Return liver, kidney channel.
Function cures mainly: promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.For colic of cold type stomachache, painful and swollen testis.
Rhizoma Atractylodis: warm in nature, acrid in the mouth, hardship.
Function cures mainly: dispeling the wind, it is dirty to ward off, drying damp and strengthening spleen, is applicable to gastral cavilty vexed, and the large loose stool of abdominal distention is soft, vomiting and nausea, extremity asthenia, and seasonal epidemic pathogens is caught a cold, all diseases of abundant expectoration.
Radix Trichosanthis: sweet, micro-hardship, is slightly cold.Attach to the lung and stomach meridians.
Function cures mainly: clearing away heat and promoting production of body fluid, detumescence and apocenosis.For calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.
Radix Salviae Miltiorrhizae: bitter, is slightly cold.GUIXIN, Liver Channel.
Function cures mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, and clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.
Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Folium Mori: sweet, bitter, cold.Return lung, Liver Channel.
Function cures mainly: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.
Pumex:
returnlung; Kidney; Liver; Large intestine channel.
Function cures mainly: lung heat clearing fire; Change old expectorant; Relieving stranguria by diuresis; Hard masses softening and resolving.Cure mainly phlegm-heat obstructing in the lung; The thick difficulty of cough with asthma expectorant is coughed up; The puckery pain of dribbling urination; Goiter scrofula.
Radix Aconiti Lateralis Preparata: pungent, sweet is warm greatly; Poisonous.GUIXIN, kidney, spleen channel.
Function cures mainly: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Pericarpium Granati: sour, puckery, temperature.Return large intestine channel.
Function cures mainly: relieving diarrhea with astringents, hemostasis, anthelmintic.For chronic diarrhea, chronic dysentery, has blood in stool, proctoptosis, metrorrhagia, leucorrhea, abdominal pain due to worm stagnation.
Semen Nelumbinis: sweet, puckery are flat.Return spleen, kidney, heart channel.
Function cures mainly: spleen reinforcing antidiarrheal, kidney tonifying arresting seminal emission, tranquilizing by nourishing the heart.For insufficiency of the spleen chronic diarrhea, seminal emission leukorrhagia, palpitation and insomnia.
Ootheca Mantidis: sweet, salty is flat.Return liver, kidney channel.
Function cures mainly: supplementing the kidney to control the nocturnal, reducing urination, only turbid.For emission and spermatorrhea, enuresis frequent micturition, urine nebulousurine.
Semen Euryales: sweet, puckery is flat.Return spleen, kidney channel.
Function cures mainly: supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, damp eliminating leukorrhagia stopping.For emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.
Fructus Rosae Laevigatae: sour, sweet, puckery, flat.Return kidney, bladder, large intestine channel.
Function cures mainly: controlling nocturnal emission with astringent drugs reducing urination, relieving diarrhea with astringents.For emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, chronic diarrhea chronic dysentery.
Flos Chrysanthemi: sweet, bitter, is slightly cold.Return lung, Liver Channel.
Function cures mainly: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.
Semen Astragali Complanati: sweet, temperature.Return liver, kidney channel.
Function cures mainly: temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, improving eyesight.For lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision.
Rhizoma Polygonati Odorati: sweet, is slightly cold.Attach to the lung and stomach meridians.
Function cures mainly: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.
Semen oryzae sativae: sweet is flat.Enter spleen, stomach warp.
Function cures mainly: invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, relieving thirst and restlessness, antidiarrheal dysentery.
Radix Puerariae: sweet, pungent, cool.Return spleen, stomach warp.
Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Rhizoma Polygonati: sweet is flat.Return spleen, lung, kidney channel.
Function cures mainly: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
The preparation of a kind of effective treatment diabetes of the present invention is made up of the crude drug of following weight ratio:
Radix Pseudostellariae 10-20 part, Poria 5-10 part, Radix Asparagi 5-15 part, Rhizoma Dioscoreae 10-20 part,
Fructus Lycii 15-30 part, Fructus Mume 3-10 part, Endothelium Corneum Gigeriae Galli 5-12 part, Fructus Mori 3-10 part,
Semen Litchi 5-15 part, Rhizoma Atractylodis 10-20 part, Radix Trichosanthis 10-20 part, Radix Salviae Miltiorrhizae 15-25 part,
Fructus Schisandrae Chinensis 5-15 part, Folium Mori 5-10 part, Pumex 10-20 part, Radix Aconiti Lateralis Preparata 10-20 part,
Pericarpium Granati 5-15 part, Semen Nelumbinis 10-20 part, Ootheca Mantidis 8-15 part, Semen Euryales 10-20 part,
Fructus Rosae Laevigatae 5-10 part, Flos Chrysanthemi 15-25 part, Semen Astragali Complanati 3-10 part, Rhizoma Polygonati Odorati 8-20 part,
Semen oryzae sativae 5-15 part, Radix Puerariae 3-10 part, Rhizoma Polygonati 3-10 part;
Preparation method:
(1), according to formula proportion, Poria, Radix Asparagi, Rhizoma Dioscoreae, Fructus Lycii, Fructus Mume, Fructus Mori, Semen Litchi, Rhizoma Atractylodis, Radix Trichosanthis, Radix Salviae Miltiorrhizae, Fructus Schisandrae Chinensis, Folium Mori, Pumex, Radix Aconiti Lateralis Preparata, Semen Nelumbinis, Semen Euryales, Fructus Rosae Laevigatae, Flos Chrysanthemi, Semen Astragali Complanati, Rhizoma Polygonati Odorati, Semen oryzae sativae, Rhizoma Polygonati are immersed 40-60 minute in 600-1000 part water, decoct 1-2 hour, after filtrate, medicinal residues add 300-500 part decocting 15 minutes, filtrate waste, is concentrated into thick paste post-drying by twice filtrate mixing and is crushed to 300-400 order fine powder;
(2), by formula proportion, Endothelium Corneum Gigeriae Galli, Ootheca Mantidis, Pericarpium Granati, Radix Pseudostellariae, Radix Puerariae are screened, put into pressure cooker and steam 20-40 minute in 150-180 DEG C, be cooled to room temperature, spread be placed in sunlight with black cloth covering on bamboo mat under and dry, be ground into 300-400 object fine powder for subsequent use;
(3) the fine powder mix homogeneously, by preparation method (1), (2) obtained, to seal after 72 hours point encapsulated.
The preparation of a kind of effective treatment diabetes of the present invention is made up of the crude drug of following weight ratio:
Radix Pseudostellariae 12-18 part, Poria 6-8 part, Radix Asparagi 8-12 part, Rhizoma Dioscoreae 12-18 part,
Fructus Lycii 20-25 part, Fructus Mume 5-8 part, Endothelium Corneum Gigeriae Galli 6-10 part, Fructus Mori 4-7 part,
Semen Litchi 8-12 part, Rhizoma Atractylodis 12-18 part, Radix Trichosanthis 12-15 part, Radix Salviae Miltiorrhizae 18-22 part,
Fructus Schisandrae Chinensis 8-12 part, Folium Mori 6-8 part, Pumex 12-18 part, Radix Aconiti Lateralis Preparata 15-18 part,
Pericarpium Granati 8-12 part, Semen Nelumbinis 12-18 part, Ootheca Mantidis 10-14 part, Semen Euryales 15-18 part,
Fructus Rosae Laevigatae 6-8 part, Flos Chrysanthemi 18-22 part, Semen Astragali Complanati 5-8 part, Rhizoma Polygonati Odorati 10-15 part,
Semen oryzae sativae 8-12 part, Radix Puerariae 5-8 part, Rhizoma Polygonati 5-8 part.
The preparation of a kind of effective treatment diabetes of the present invention is made up of the crude drug of following weight ratio:
Radix Pseudostellariae 15 parts, 7 parts, Poria, Radix Asparagi 10 parts, Rhizoma Dioscoreae 15 parts,
Fructus Lycii 22 parts, Fructus Mume 6 parts, Endothelium Corneum Gigeriae Galli 8 parts, 5 parts, Fructus Mori,
Semen Litchi 10 parts, Rhizoma Atractylodis 15 parts, Radix Trichosanthis 14 parts, Radix Salviae Miltiorrhizae 20 parts,
Fructus Schisandrae Chinensis 10 parts, 7 parts, Folium Mori, Pumex 15 parts, Radix Aconiti Lateralis Preparata 16 parts,
Pericarpium Granati 10 parts, 15 parts, Semen Nelumbinis, Ootheca Mantidis 12 parts, Semen Euryales 16 parts,
Fructus Rosae Laevigatae 7 parts, Flos Chrysanthemi 20 parts, Semen Astragali Complanati 7 parts, Rhizoma Polygonati Odorati 12 parts,
Semen oryzae sativae 10 parts, Radix Puerariae 7 parts, Rhizoma Polygonati 6 parts.
The preparation of a kind of effective treatment diabetes of the present invention has hypoglycemic effect obviously, and side effect is little, spleen benefiting and strengthen kidney, nourishing YIN and invigorating YANG, the effects such as mediation the five internal organs, treating both the principal and secondary aspects of a disease, can impel pancreatic cell regeneration after medicine enters body, strengthen the secretion of insulin, the metabolism of sugar in body can be improved, the consumption of insulin can be reduced rapidly the patient relying on insulin, can blood fat be reduced simultaneously, prevent arteriosclerosis, and have good prevention effect to the multiple complications that diabetes cause.
Embodiment 5
Radix Pseudostellariae 15g, Poria 7g, Radix Asparagi 10g, Rhizoma Dioscoreae 15g,
Fructus Lycii 22g, Fructus Mume 6g, Endothelium Corneum Gigeriae Galli 8g, Fructus Mori 5g,
Semen Litchi 10g, Rhizoma Atractylodis 15g, Radix Trichosanthis 14g, Radix Salviae Miltiorrhizae 20g,
Fructus Schisandrae Chinensis 10g, Folium Mori 7g, Pumex 15g, Radix Aconiti Lateralis Preparata 16g,
Pericarpium Granati 10g, Semen Nelumbinis 15g, Ootheca Mantidis 12g, Semen Euryales 16g,
Fructus Rosae Laevigatae 7g, Flos Chrysanthemi 20g, Semen Astragali Complanati 7g, Rhizoma Polygonati Odorati 12g,
Semen oryzae sativae 10g, Radix Puerariae 7g, Rhizoma Polygonati 6g;
Preparation method:
(1), Poria, Radix Asparagi, Rhizoma Dioscoreae, Fructus Lycii, Fructus Mume, Fructus Mori, Semen Litchi, Rhizoma Atractylodis, Radix Trichosanthis, Radix Salviae Miltiorrhizae, Fructus Schisandrae Chinensis, Folium Mori, Pumex, Radix Aconiti Lateralis Preparata, Semen Nelumbinis, Semen Euryales, Fructus Rosae Laevigatae, Flos Chrysanthemi, Semen Astragali Complanati, Rhizoma Polygonati Odorati, Semen oryzae sativae, Rhizoma Polygonati to be immersed in 800 parts of water 50 minutes according to formula proportion, decoct 1.5 hours, after filtrate, medicinal residues add 400 parts of decoctings 15 minutes, filtrate waste, is concentrated into thick paste post-drying by twice filtrate mixing and is crushed to 300 order fine powders;
(2), by formula proportion by Endothelium Corneum Gigeriae Galli, Ootheca Mantidis, Pericarpium Granati, Radix Pseudostellariae, Radix Puerariae screening, height is put into
Pressure pot steams 30 minutes in 170 DEG C, is cooled to room temperature, spreads be placed in sunlight with black cloth covering on bamboo mat under and dries, be ground into 300 object fine powders for subsequent use;
(3) the fine powder mix homogeneously, by preparation method (1), (2) obtained, to seal after 72 hours point encapsulated.
MethodsThe cases enrolled: in through curing with this prescription 100 routine patients, wherein man 57 example, female 43 example is the course of disease the shortest half a year, the longest 15 years.Take maximum four the course for the treatment of transference cure, total effective rate 96%, aobvious more rate 85%, shows that this medicine has obvious curative effects to diabetics.
Efficacy determination: adopt 4 grade standards
Recovery from illness clinical improvements rate >=95%;
Effective clinical improvements rate < 95%, >=60%;
Effective clinical improvement rate < 60%, >=20%;
Invalid clinical improvements rate < 20%;
Therapeutic outcome is in Table
|
Recovery from illness (routine %) |
Effective (routine %) |
Effectively (routine %) |
Invalid (routine %) |
Effective percentage (%) |
Latter 2 weeks for the treatment of |
3(3) |
17(17) |
52(52) |
28(28) |
72 |
Latter 3 weeks for the treatment of |
25 (25) |
32(32) |
28(28) |
15(15) |
85 |
Latter 4 weeks for the treatment of |
51(51) |
20(20) |
18 (18) |
11(11) |
89 |
Latter 5 weeks for the treatment of |
85(85) |
6(6) |
5(5) |
4(4) |
96 |
Model case:
Case 1:
Zheng x, sex: female's age: 35.The first visit time: on May 25th, 2002, diagnosis: type 2 diabetes mellitus
Treatment situation: after hospitalization one course for the treatment of, hematuria sugar is basicly stable, and fully recover after taking for 2 courses for the treatment of continuously, complication fades.Drug withdrawal is followed up a case by regular visits to for 2 years so far, without recurrence sign.
Case 2:
Old xx, sex: man's age: 50.The first visit time: on December 4th, 2005, diagnosis: general type 2 diabetes mellitus treatment situation: time to our hospital, blood glucose is high, through treatment and the nursing of 3 courses for the treatment of of my institute, patient satisfies withdrawal, normal diet.Within in 1 year every two months, look on an empty stomach and after the meal 2 hours blood glucoses all in normal range.
Follow up a case by regular visits to and do not recur so far.
Case 3:
Liu xx, sex: man's age: 54 first visit times: calendar year 2001 JIUYUE 6 days, diagnosis: diabetic complication renal diseases hypertension treatment situation: patient weak companion Nausea and vomiting, two lower limb are without edema, nearly half a year is without sweating; urine is that clear water sample, amount are much in my institute's application Chinese medicine Shuan Shen district infiltration; have sweating, appetite takes a turn for the better, and 2 courses for the treatment of are discharged from hospital after recovery.
Case 4:
Poplar x, sex: man's age: 43 first visit times: on May 8th, 2000, diagnosis: type 2 diabetes mellitus complications Treatment situation: glucose in urine (++) when coming my institute, fasting glucose 5-8mmol/L, soreness of the waist and knees, metal fatigue, defecates partially dry, in my institute's application treatment by Chinese herbs, look into after January: blood glucose 5.3mmoI/L, glucose in urine (), connect again treatment 2 course for the treatment of, drug withdrawal. 1 year so far, follow up a case by regular visits to and do not recur.
Case 5:
Beam X, sex: man's age: 66 first visit times: on October 20th, 2005, diagnosis: complication chronic nephritis treatment situation: when being admitted to hospital, spirit is poor, accompany uncomfortable in chest, face and extremity without edema, Shuan Shen district is without percussion pain, give treatment by Chinese herbs after treatment and improve blood circulation of kidney, purged body endotoxin, anemia etc. to recover renal function.Hospitalization is left hospital for 11 days.Sensation of oppression over the chest with shortness of breath transference cure.
Case 6:
Old x, sex: man's age: 51 first visit times: on April 28th, 2003, diagnosis: type 2 diabetes mellitus treatment situation: thirsty, polydipsia before treatment, to become thin, after treatment, symptom disappears substantially, through reviewing patient's islet function, and Insulin receptor INSR, blood fat is normal, patient satisfies withdrawal, in normal diet situation, follows up a case by regular visits to and does not recur so far.
Case 7:
Open xx, sex: female's age: 63 first visit times: on May 4th, 2003, diagnosis: diabetic complication renal diseases hypertension treatment situation: patient weak companion Nausea and vomiting, two lower limb are without edema, nearly half a year is without sweating; urine is that clear water sample, amount are much in my institute's application Chinese medicine Shuan Shen district infiltration; have sweating, appetite takes a turn for the better, and two courses for the treatment of are discharged from hospital after recovery.
Case 8:
Open x, sex: female's age: 43 first visit times: May 8 calendar year 2001, diagnosis: type 2 diabetes mellitus also
Send out disease treatment situation: glucose in urine (++) when coming my institute, fasting glucose 5-8mmol/L, soreness of the waist and knees, metal fatigue, defecate partially dry, in my institute's application treatment by Chinese herbs, look into after January: blood glucose 5.3mmoI/L, glucose in urine (), connect again treatment 2 course for the treatment of, drug withdrawal. 1 year so far, follow up a case by regular visits to and do not recur.
Case 9:
Zhao x, sex: man's age: 30.The first visit time: on May 25th, 2002, diagnosis: type 2 diabetes mellitus treatment situation: after hospitalization 1 course for the treatment of, hematuria sugar is basicly stable, and fully recover after taking for 2 courses for the treatment of continuously, complication fades.Drug withdrawal is followed up a case by regular visits to for 2 years so far, without recurrence sign.
Case 10:
Liu xx, sex: man's age: 50.The first visit time: on December 4th, 2002, diagnosis: general type 2 diabetes mellitus treatment situation: time to our hospital, blood glucose is high, and through treatment and the nursing of 2 courses for the treatment of, patient satisfies withdrawal, normal diet.Within in 1 year every two months, look on an empty stomach and after the meal 2 hours blood glucoses all in normal range.Follow up a case by regular visits to and do not recur so far.