CN102415408A - Composite insecticidal composition containing dinotefuran and chlopyrifos and purpose thereof - Google Patents
Composite insecticidal composition containing dinotefuran and chlopyrifos and purpose thereof Download PDFInfo
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- CN102415408A CN102415408A CN2010102998245A CN201010299824A CN102415408A CN 102415408 A CN102415408 A CN 102415408A CN 2010102998245 A CN2010102998245 A CN 2010102998245A CN 201010299824 A CN201010299824 A CN 201010299824A CN 102415408 A CN102415408 A CN 102415408A
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Abstract
The invention discloses a composite insecticidal composition containing dinotefuran and chlopyrifos and purpose thereof. The insecticidal composition contains main effective components of dinotefuran and chlopyrifos in a mass ratio of 0.1-80:0.5-80. The insecticidal composition of the invention can be used for controlling homoptera insects on crops, especially for controlling rice hopper and aphid, can generate efficient synergism, overcome and delay resistance of insects, and has fast insecticidal speed, long persistent period, reduced drug usage cost and an effect obvious better than that of a single dose.
Description
Technical field
The invention belongs to pesticide field, be specifically related to a kind of compound pesticide compositions that contains MTI-446 and chlopyrifos and uses thereof.
Background technology
MTI-446 (dinotefuran), chemical name: 1-methyl-2-nitro-3-(tetrahydrochysene-3-furfuryl) guanidine, white crystal, 107.5 ℃ of fusing points, 94.5～101.5 ℃ of industrial goods, vapour pressure＜1.7 * 10-6pa (30 ℃), density 1.33 (25 ℃).Solvability is water 40g/L, is insoluble in cyclohexane, solvent wet goods organic solvent.Structural formula is:
MTI-446 is fool proof to mammal, and its acute oral LD50 is male rat 2450mg/kg, female rats 2275mg/kg; Male mice 2840mg/kg, female mice 2000mg/kg.To rat acute through skin LD50＞2000mg/kg (female, hero).No teratogenesis, carcinogenic and mutagenicity.MTI-446 is also fool proof to aquatile.The ichthyotoxin test shows that MTI-446 is to carp nm (48h)＞1000mg/L, to water flea＞1000mg/L; Equally, MTI-446 is also very low to birds toxicity, and through the honeybee test is learnt, MTI-446 is to honeybee safety to quail acute oral LD50＞1000mg/kg., and do not influence honeybee producting honey.This medicament insecticidal spectrum is wide, has remarkable interior suction osmosis, and has promptly shown very high insecticidal activity at very low dosage.This medicament is fool proof to mammal, birds and aquatile, and crop is not had poisoning, can be used for numerous crops such as paddy rice, fruit tree, vegetables.
Chlopyrifos (chlorpyrifos) is a kind of broad spectrum insecticide of The Dow Agrosciences, LLC.'s exploitation, and the trade name of registering in China is Le Siben.Have another name called: the chlorine pyrazothion, chemical name is: O, O-diethyl-O-(3,5, the 6-trichloro-2-pyridyl) thiophosphate; Structural formula is:
Former medicine is white or canescence graininess crystal (or blocks of solid), 41.5～43.5 ℃ of fusing points; Poisonous to fish and honeybee, responsive to tobacco.Chlopyrifos is one of maximum insecticide variety of present produced worldwide and sales volume, also is the organic phosphor kind of the unique permission of the World Health Organization, and is existing in 14 country's registrations such as China, the U.S., Australia, Japan and registration.This kind have tag, stomach toxicity and stifling three kinds of modes of action; Its insecticidal spectrum is wide, toxicity is lower, efficient equally to the ground soil insect; It is the desirable insecticide of control grain, fruit tree, vegetables and other economic crops insect pests; Control efficiency to underground insect is particularly outstanding, is particularly suitable for being applied to the production of pollution-free vegetable.
At present, homoptera pest, particularly rice fulgorid and aphid are under the condition of long-term prescription, and resistance increases gradually, and the agent of agricultural chemicals list descends to the effect of control of insect gradually.The inventor finds after deliberation, but the synergistic complex expanding prevention of agricultural chemicals is composed and the raising preventive effect, does not find the Pesticidal combination of relevant MTI-446 and chlopyrifos up to now as yet.
Summary of the invention
The purpose of this invention is to provide a kind of compound pesticide compositions that contains MTI-446 and chlopyrifos, this Pesticidal combination is the multifunctional insecticide composition of control homoptera pest.
Another object of the present invention provides this compound pesticide compositions and prevents and treats the application on the insecticidal materials of resistance homoptera pest in preparation, particularly the application on the insecticidal materials of preparation control plant hopper, aleyrodid or aphid.
The objective of the invention is to realize through following technical scheme:
A kind of compound pesticide compositions that contains MTI-446 and chlopyrifos, this Pesticidal combination is main active ingredient with MTI-446 and chlopyrifos, wherein, the weight ratio of MTI-446 and chlopyrifos is 0.1～80: 0.5～80.Be preferably 0.5～50: 2～50, further be preferably 0.5～10: 4～30.Effective ingredient is present in the composition with the synergy effective dose in this Pesticidal combination.
In compound pesticide compositions of the present invention, the two weight percentage in this compound pesticide compositions of MTI-446 and chlopyrifos is 3%～80%.Be preferably 5%～55%, most preferably 10%～40%.
Compound pesticide compositions of the present invention is that main active ingredient and insecticides adjuvant and excipient are mixed with any one formulation that allows on the agricultural chemicals, the preferred emulsion of described formulation, suspending agent, wetting powder, aqueous emulsion, microemulsion or water dispersion granule with MTI-446 and chlopyrifos.
Auxiliary agent can adopt calcium dodecyl benzene sulfonate, APES, polyoxyethylene polyoxy third rare block compound (like farming breast 33
#), NPE etc., excipient comprises cyclohexanone, xylol, solvent naphtha, water, antifreezing agent (like propane diols), deionized water etc.Above auxiliary agent, excipient and other auxiliary material can singly be used or mix and use.
Compound pesticide compositions of the present invention has good preventive effect to the multiple homoptera pest that rice fulgorid and aphid etc. is easy to generate resistance; And the inhibition insect is to the pesticide resistance generation of single preparation (MTI-446 or chlopyrifos are arbitrary).
The compound pesticide compositions that the present invention contains MTI-446 and chlopyrifos can be used for preparing the insecticidal materials of preventing and treating the resistance homoptera pest, in particular for preparation control aleyrodid, plant hopper or aphid insecticidal materials.
Beneficial effect compared with prior art of the present invention: compare with single agent; Said composition antagonism homoptera pest such as rice fulgorid, aphid etc. have obvious synergistic function, overcome and have delayed pest resistance to insecticide, the expanding prevention spectrum; Desinsection speed is fast, has obviously improved control efficiency; Reduce control recruitment, drug cost; Alternative high-toxic pesticide; Have concurrently quick-acting and long-acting; Compare with MTI-446 and the single agent of chlopyrifos, produce and the use cost reduction; Suppress the resistance enhancing of homoptera pest to agricultural chemicals, its effect is used apparently higher than its single agent.
Embodiment
Below in conjunction with embodiment the present invention is described further:
Embodiment 1:
Taking by weighing MTI-446, chlopyrifos, to adopt the conventional formulation method to be mixed with main active ingredient weight percentage by different proportion be 30% MTI-446 chlorpyrifos ec.Concrete ratio is seen table 1,2.The contrast medicament is respectively 30% MTI-446 missible oil and 3% chlorpyrifos ec.
Adopt rice stem infusion process to carry out indoor synergy biologicall test, selecting the resistant rice plant hopper is target pest, every processing repetition 3 times, and every concentration is handled 60, calculates toxicity regression equation and the lethal concentration of 50 LC of each medicament antagonism rice fulgorid with probability value method
50, use LC
50Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient, and the result sees table 1:
The toxicity test of table 1 MTI-446 and chlorpyrifos mixture and single agent antagonism rice fulgorid
Can know that by table 1 MTI-446 and chlorpyrifos mixture, co-toxicity coefficient show good synergistic effects all greater than 120.
Employing is soaked the leaf dip method and is carried out indoor synergy biologicall test, and selecting the resistance wheat aphid is target pest, and every processing repetition 3 times is with toxicity regression equation and the lethal concentration of 50 LC of each medicament antagonism rice fulgorid of probability value method calculating
50, use LC
50Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient, and the result sees table 2:
The toxicity test of table 2 MTI-446 and chlorpyrifos mixture and single agent antagonism wheat aphid
Can know that by table 2 MTI-446 and chlorpyrifos mixture all greater than 120, show good synergistic effects to the co-toxicity coefficient of wheat aphid.
Embodiment 2:
Take by weighing 50g MTI-446,5g chlopyrifos, phenethyl phenol polyethenoxy ether phosphate 3g, farming breast 33
#(alkylaryl polyoxyethylene polyoxypropylene ether) 2g, APES 1g, xylol 13g adds water to 100g.Above raw material is dropped into the mixing kettle high speed by the method for routine preparation aqueous emulsion mix, form main active ingredient weight percentage and be 55% MTI-446 chlorpyrifos aqueous emulsion.
Embodiment 3:
Take by weighing 18g MTI-446,2g chlopyrifos, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphate 3g, farming breast 33
#(alkylaryl polyoxyethylene polyoxypropylene ether) 2g, APES 1g, cyclohexanone 10g adds water to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation microemulsion mix, form main active ingredient weight percentage and be 20% MTI-446 chlorpyrifos micro emulsion.
Embodiment 3 is prevented and treated the paddy rice brown planthopper test of pesticide effectiveness; The contrast medicament is 40% chlopyrifos EC (missible oil) and 20% MTI-446 AS (aqua); Extension rate according to 3 li of forms dilutes, and every mu of ground, dilution back sprays 30 kilograms of soups, looks into behind the medicine 2 days; The result of 5 days and 10 days, result is seen table 3:
Table 3: the MTI-446 chlorpyrifos mixture is to the field test results of paddy rice brown planthopper
Field efficacy is the result show, MTI-446 chlopyrifos composition antagonism brown planthopper has good control efficiency, and control efficiency all is better than single agent kind.
Embodiment 3 is prevented and treated the wheat aphid field medicine effect test; The contrast medicament is 40% chlopyrifos EC (missible oil) and 20% MTI-446 AS (aqua); Extension rate according to 3 li of forms dilutes, and the consumption medication that 30Kg/ mu is pressed in the dilution back was looked into behind the medicine 2 days; The result of 5 days and 10 days, result is seen table 4:
Table 4: the MTI-446 chlorpyrifos mixture is to the field test results of wheat aphid
Field efficacy is the result show, MTI-446 chlopyrifos composition antagonism wheat aphid has good control efficiency, and control efficiency all is better than the effect that single agent kind is better than direct each Dan Pin of while.
Embodiment 4:
Take by weighing 1g MTI-446,5g chlopyrifos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, xylol to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 6% MTI-446 chlorpyrifos ec.
Embodiment 5:
Take by weighing 50g MTI-446,20g chlopyrifos, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 2g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 70% MTI-446 chlorpyrifos ec.
Embodiment 6:
Take by weighing 2g MTI-446,40g chlopyrifos, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 5g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 42% MTI-446 chlorpyrifos ec.
Embodiment 7:
Take by weighing 0.2g MTI-446,50g chlopyrifos, calcium dodecyl benzene sulfonate 9g, phenethyl phenol polyethenoxy ether 8g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 50.2% MTI-446 chlorpyrifos ec.
Embodiment 8:
Take by weighing 5g MTI-446,0.5g chlopyrifos, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 7g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 5.5% MTI-446 chlorpyrifos ec.
Embodiment 9:
Take by weighing 30g MTI-446,6g chlopyrifos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 36% MTI-446 chlorpyrifos ec.
Embodiment 10:
Take by weighing 20g MTI-446,5g chlopyrifos, calcium dodecyl benzene sulfonate 7g, phenethyl phenol polyethenoxy ether 9g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 25% MTI-446 chlorpyrifos ec.
Embodiment 11:
Take by weighing 30g MTI-446,12g chlopyrifos, sodium lignin sulfonate 2g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof; Xanthans 0.15g; Ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g; Water complements to 100g, and the main active ingredient weight percentage of formation is 42% MTI-446 chlopyrifos suspending agent under the effect of sand mill.
Embodiment 12:
Take by weighing 2g MTI-446,5g chlopyrifos; Sodium lignin sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g; Polyvinyl alcohol 5g; Borax 2g, diatomite 21g, it is 7% MTI-446 chlopyrifos water dispersion granule that above raw material is formed main active ingredient weight percentage by the water dispersible granular agent method.
Embodiment 13:
Take by weighing 50g MTI-446,3g chlopyrifos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 53% MTI-446 chlorpyrifos ec.
Embodiment 14:
Take by weighing 2g MTI-446,18g chlopyrifos; Sodium lignin sulfonate 10g, Negel 2g, add to 100g with diatomite; Above raw material is mixed in micronizer, form main active ingredient weight percentage and be 20% MTI-446 chlopyrifos wetting powder.
Embodiment 15:
Take by weighing 7g MTI-446,70g chlopyrifos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, xylol are to 100g.Above raw material dropped in the mixing kettle by the method for routine preparation missible oil mix, form main active ingredient weight percentage and be 77% MTI-446 chlorpyrifos ec.
Embodiment 16:
Take by weighing 60g MTI-446,5g chlopyrifos, sodium lignin sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g; Polyvinyl alcohol 5g; Borax 2g; Kaolin 13g, it is 65% MTI-446 chlopyrifos water dispersible granules that above raw material is formed main active ingredient weight percentage by the water dispersible granular agent method.
Claims (9)
1. a compound pesticide compositions that contains MTI-446 and chlopyrifos is characterized in that this Pesticidal combination is main active ingredient with MTI-446 and chlopyrifos, and wherein, the weight ratio of MTI-446 and chlopyrifos is 0.1～80: 0.5～80.
2. the compound pesticide compositions that contains MTI-446 and chlopyrifos according to claim 1, the weight ratio that it is characterized in that described MTI-446 and chlopyrifos is 0.5～50: 2～50.
3. the compound pesticide compositions that contains MTI-446 and chlopyrifos according to claim 2, the weight ratio that it is characterized in that described MTI-446 and chlopyrifos is 0.5～10: 4～30.
4. the compound pesticide compositions that contains MTI-446 and chlopyrifos according to claim 1 is characterized in that the two weight percentage in this compound pesticide compositions of MTI-446 and chlopyrifos is 3%～80%.
5. the compound pesticide compositions that contains MTI-446 and chlopyrifos according to claim 4 is characterized in that the two weight percentage in this compound pesticide compositions of MTI-446 and chlopyrifos is 5%～55%.
6. the compound pesticide compositions that contains MTI-446 and chlopyrifos according to claim 1 is characterized in that this compound pesticide compositions is that main active ingredient and insecticides adjuvant, excipients are mixed with any one formulation that allows on the agricultural chemicals with MTI-446 and chlopyrifos.
7. the compound pesticide compositions that contains MTI-446 and chlopyrifos according to claim 6 is characterized in that said formulation is missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion or water dispersion granule.
8. the described compound pesticide compositions that contains MTI-446 and chlopyrifos of claim 1 is prevented and treated the application on the insecticidal materials of resistance homoptera pest in preparation.
9. the compound pesticide compositions that contains MTI-446 and chlopyrifos according to claim 8 anti-ly eliminates aphis in preparation, the application on the insecticidal materials of aleyrodid or plant hopper.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102998245A CN102415408A (en) | 2010-09-28 | 2010-09-28 | Composite insecticidal composition containing dinotefuran and chlopyrifos and purpose thereof |
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| CN2010102998245A CN102415408A (en) | 2010-09-28 | 2010-09-28 | Composite insecticidal composition containing dinotefuran and chlopyrifos and purpose thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101978832A (en) * | 2010-11-29 | 2011-02-23 | 陕西韦尔奇作物保护有限公司 | Pesticide composition containing dinotefuran and chlorpyrifos |
| CN103444772A (en) * | 2013-09-13 | 2013-12-18 | 陆学云 | Dinotefuran-containing pesticide |
| CN110476959A (en) * | 2015-10-16 | 2019-11-22 | 江苏龙灯化学有限公司 | A kind of Pesticidal combination of containing chlopyrifos and dinotefuran |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1046508C (en) * | 1993-10-26 | 1999-11-17 | 三井化学株式会社 | Furanyl insecticide |
| JP2002249406A (en) * | 2000-12-20 | 2002-09-06 | Sankei Kagaku Kk | Vermicide for agriculture and gardening |
-
2010
- 2010-09-28 CN CN2010102998245A patent/CN102415408A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1046508C (en) * | 1993-10-26 | 1999-11-17 | 三井化学株式会社 | Furanyl insecticide |
| JP2002249406A (en) * | 2000-12-20 | 2002-09-06 | Sankei Kagaku Kk | Vermicide for agriculture and gardening |
Non-Patent Citations (3)
| Title |
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| 《世界农药》 20031025 张亦冰 新内吸杀虫剂--呋虫胺 1-9 第25卷, 第5期 * |
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| 程志明: "新型杀虫剂呋虫胺的创制", 《世界农药》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101978832A (en) * | 2010-11-29 | 2011-02-23 | 陕西韦尔奇作物保护有限公司 | Pesticide composition containing dinotefuran and chlorpyrifos |
| CN103444772A (en) * | 2013-09-13 | 2013-12-18 | 陆学云 | Dinotefuran-containing pesticide |
| CN110476959A (en) * | 2015-10-16 | 2019-11-22 | 江苏龙灯化学有限公司 | A kind of Pesticidal combination of containing chlopyrifos and dinotefuran |
| CN110476959B (en) * | 2015-10-16 | 2022-08-26 | 江苏龙灯化学有限公司 | Insecticidal composition containing chlorpyrifos and dinotefuran |
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Application publication date: 20120418 |