CN102353658B - Miniature IOT laser-induced breakdown spectroscopy medical sensing system and method - Google Patents
Miniature IOT laser-induced breakdown spectroscopy medical sensing system and method Download PDFInfo
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- CN102353658B CN102353658B CN 201110187552 CN201110187552A CN102353658B CN 102353658 B CN102353658 B CN 102353658B CN 201110187552 CN201110187552 CN 201110187552 CN 201110187552 A CN201110187552 A CN 201110187552A CN 102353658 B CN102353658 B CN 102353658B
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Abstract
The invention discloses a miniature IOT (Internet of Things) laser-induced breakdown spectroscopy medical sensing system and a method. In the optical-electro-mechanical structure of the system, all the electronic circuits of power supply, control, refrigeration, mems raster spectrometer , buffer memory, IOT personal identification, IOT data transmission functions are centralized in a miniature circuit system; all the optical elements are centrailized in a miniature pulsed optical fiber laser system; and the structure raises the miniaturization degree of the system and satisfies the miniaturization requirement of the IOT senor. When applied in medicine, a microcontroller (MCU) controls a ZigBee transceiver module to send a libs signal, which is generated when biological tissues such as hair of a system-carrying person are hit by laser of the miniature pulsed optical fiber laser system, to the IOT server expert system for analysis, diagnosis and storage, and the diagnosis result of the expert system can be received by the ZigBee transceiver module.
Description
Technical field
This patent relates to a kind of medical science sensor-based system, specifically refers to a kind of Mini-type internet-of-things laser induced breakdown spectroscopy medical sensor system and method, and it can be used for the Internet of Things medical diagnosis.
Background technology
Along with the day by day prosperity of infotech, Internet of Things will be widely used in the numerous areas such as intelligent transportation, environmental protection, government work, public safety, personal health, safety home.The support technology of Internet of Things has then merged the multiple technologies such as sensor technology, RFID (radio-frequency (RF) identification), computer technology, communication network technology, electronic technology.Wherein sensor technology is one of gordian technique of construct networking, compares with other sensors, and the portable medical demand sensor is comparatively special.Along with the development of economy and society, people's health perception, health demand and medical payment ability just improve constantly so that portable medical sensor product particularly household portable medical sensor produce market demand enlarge steadily.The present medical sensor kind that is applicable to the Internet of Things application seldom needs the adding of novel Internet of Things medical sensor, enriches user's selection.Based on Laser-induced breakdown spectroscopy (being called for short libs), the medical science sensing technology development that is Laser-induced Breakdown Spectroscopy is very fast, wherein adopts libs effect analysis people's hair, nail etc. to organize the formation of various trace elements and a kind of novel method that ratio has become health diagnosis and monitoring.But present libs medical analysis system bulky can't be fit to the requirement of Internet of Things medical science Application in Sensing, needs miniaturized system and designs the transmission of Internet of Things medical science libs signal and diagnostic method.
This patent is for the demand of novel Internet of Things medical sensor, a kind of baby networking laser libs (Laser-induced breakdown spectroscopy is proposed, be Laser-induced Breakdown Spectroscopy) medical science sensor-based system and method, it can be used for the Internet of Things medical diagnosis.
Summary of the invention
The purpose of this patent provides a kind of baby networking laser libs (Laser-induced breakdown spectroscopy, i.e. Laser-induced Breakdown Spectroscopy) medical science sensor-based system and method.The electronic circuit of all power supplies in its ray machine electricity structure, control, refrigeration, micro electronmechanical mems grating spectrograph, buffer memory, Internet of Things identification, data transmission of internet of things function all concentrates on integrated circuitry; All optical elements all concentrate on small-sized pulse optical fiber system.When medical application, controlled the biological tissue such as purple honeybee (ZigBee) transceiver module transmitting system wearer hair by microcontroller (MCU) and carried out analyzing and diagnosing and storage by libs signal to the Internet of Things server expert system of small-sized pulse optical fiber system laser, and can receive by purple honeybee (ZigBee) transceiver module the diagnostic result of expert system.
The beneficial effect of this patent is the microminiaturized degree that this structure has improved system, has satisfied the miniaturization requirement of internet of things sensors.
The technical scheme of this patent is achieved like this, at first control purple honeybee (ZigBee) transceiver module according to IEEE802.15.4 agreement wireless connections Internet of Things, the then long-range completion system wearer of radio frequency discrimination RFID module authentication by microcontroller (MCU).Microcontroller (MCU) sends enabling signal to pulse producer, makes 1064nm impulse semiconductor seed laser emission single mode pulse seed laser, through signal optical fibre and optoisolator to pumping/signal bundling device; Semiconductor pump laser (pumping wavelength 915nm) sends the 915nm pumping laser and also arrives pumping/signal bundling device through pumping optical fiber and pumping protection wave filter; seed laser and pumping laser enter through pumping/signal bundling device mixes ytterbium silica fibre amplifier, exports high power 1064nm pulsed infrared laser light to exporting optoisolator after Yb dosed optical fiber amplifies.The tissues such as system wearer's hair nail are placed on the support, after the high power 1064nm pulsed infrared laser light that is produced by small-sized pulse optical fiber system hits, plasma based on the generation of libs effect, entered micro electronmechanical (mems) grating spectrograph through fiber coupler by the fixing optical fiber collection of an end, the plasma resonance signal produces the libs spectral signal through miniature self aggregation concave surface blazed grating diffraction.When microcontroller (MCU) sends enabling signal to pulse producer, enabling signal produces delaying time to the CCD Drive and Control Circuit of a microsecond magnitude through digital delay pulse producer DG535, to start line array CCD exposure libs spectral signal, this libs spectral signal deposits first the CCD output state in.Then libs signal to the Internet of Things server expert system of being controlled in purple honeybee (ZigBee) the transceiver module transmission CCD output state by microcontroller (MCU) is carried out analyzing and diagnosing and storage, and can receive by purple honeybee (ZigBee) transceiver module the diagnostic result of expert system.
Description of drawings
Fig. 1 is the schematic diagram of this patent, among the figure: 1---and purple honeybee ZigBee transceiver module; 2---the radio frequency discrimination RFID module; 3---integrated circuitry; 4---microcontroller; 5---pulse producer; 6---pump laser driving circuit and semiconductor cooler; 7---the seed laser driving circuit; 8---1064nm impulse semiconductor seed laser; 9---the semiconductor pump laser of pumping wavelength 915nm; 10---signal optical fibre; 11---the pumping protection wave filter; 12---pumping optical fiber; 13---optoisolator; 14-pumping/signal bundling device; 15---mix ytterbium silica fibre amplifier; 16---the output optoisolator; 17---the tissues such as hair nail; 18---small-sized pulse optical fiber system; 19---support; 20---plasma; 21---fiber coupler; 22---optical fiber; 23---micro electronmechanical mems grating spectrograph; 24---the optical fiber fixed port; 25---line array CCD; 26---miniature self aggregation concave surface blazed grating; 27---the CCD Drive and Control Circuit; 28---digital delay pulse producer DG535; 29---the CCD output state.
Embodiment
The principle of this patent as shown in Figure 1, whole system comprises 18 two major parts of integrated circuitry 3 and small-sized pulse optical fiber system.
The internet of things functional assembly includes purple honeybee ZigBee transceiver module 1 and radio frequency discrimination RFID module 2; The seed laser assembly includes pulse producer 5, seed laser driving circuit 7 and 1064nm impulse semiconductor seed laser 8; The pump laser assembly includes the semiconductor pump laser 9 of pump laser driving circuit and semiconductor cooler 6 and pumping wavelength 915nm, and this pump laser power is larger, therefore needs with semiconductor cooler 6 cold at its work schedule; Contain optical fiber fixed port 24 (can be used to an end fixed fiber 22), line array CCD 25 and miniature self aggregation concave surface blazed grating 26 in the micro electronmechanical mems grating spectrograph 23.
The operation material of small-sized pulse optical fiber system 18 is for mixing ytterbium silica fibre amplifier 15, it provides single mode pulse seed laser by 1064nm impulse semiconductor seed laser 8, the semiconductor pump laser 9 of pumping wavelength 915nm provides pumping laser, and pumping laser selects 915nm to be because Yb dosed optical fiber is smooth to pump absorption in 895nm arrives the 925nm scope.
At first control purple honeybee ZigBee transceiver module 1 according to IEEE802.15.4 agreement wireless connections Internet of Things by microcontroller 4, then radio frequency discrimination RFID module 2 long-range completion system wearer authentications.Microcontroller 4 sends enabling signal to pulse producer 5, makes 1064nm impulse semiconductor seed laser 8 emission single mode pulse seed laser, through signal optical fibre 10 and optoisolator 13 to pumping/signal bundling device 14; The semiconductor pump laser 9 of pumping wavelength 915nm sends the 915nm pumping laser and also arrives pumping/signal bundling device 14 through pumping optical fiber 12 and pumping protection wave filter 11; seed laser and pumping laser enter through pumping/signal bundling device 14 mixes ytterbium silica fibre amplifier 15, exports high power 1064nm pulsed infrared laser lights to exporting optoisolator 16 after Yb dosed optical fiber amplifies.
The tissues 17 such as system wearer's hair nail are placed on the support 19, after the high power 1064nm pulsed infrared laser light that is produced by small-sized pulse optical fiber system 18 hits, plasma 20 based on the generation of libs effect, entered micro electronmechanical mems grating spectrograph 23 through fiber coupler 21 by fixing optical fiber 22 collections of an end, plasma 20 radiation signals produce the libs spectral signal through miniature self aggregation concave surface blazed grating 26 diffraction.
When microcontroller 4 sends enabling signal to pulse producer 5, enabling signal produces delaying time to CCD Drive and Control Circuit 27 of a microsecond magnitude through digital delay pulse producer DG53528, to start line array CCD 25 exposure libs spectral signals, this libs spectral signal deposits first CCD output state 29 in.
Then libs signal to the Internet of Things server expert system that is sent in the CCD output state 29 by the purple honeybee ZigBee transceiver module 1 of microcontroller 4 controls is carried out analyzing and diagnosing and storage, and can receive by purple honeybee ZigBee transceiver module 1 diagnostic result of expert system.
Claims (2)
1. Mini-type internet-of-things laser induced breakdown spectroscopy medical sensor system, it comprises (18) two parts of integrated circuitry (3) and small-sized pulse optical fiber system, it is characterized in that:
Described integrated circuitry (3) is by purple honeybee ZigBee transceiver module (1), radio frequency discrimination RFID module (2), microcontroller (4), pulse producer (5), pump laser driving circuit and semiconductor cooler (6), seed laser driving circuit (7), 1064nm impulse semiconductor seed laser (8), the semiconductor pump laser of pumping wavelength 915nm (9), micro electronmechanical mems grating spectrograph (23), CCD Drive and Control Circuit (27), digital delay pulse producer DG535(28) and CCD output state (29) form, wherein contain optical fiber fixed port (24) in the micro electronmechanical mems grating spectrograph (23), line array CCD (25) and miniature self aggregation concave surface blazed grating (26) three parts;
Described small-sized pulse optical fiber system (18) by signal optical fibre (10), pumping protection wave filter (11), pumping optical fiber (12), optoisolator (13), pumping/signal bundling device (14), mix ytterbium silica fibre amplifier (15) and output optoisolator (16) form;
System at first controls purple honeybee ZigBee transceiver module (1) according to IEEE802.15.4 agreement wireless connections Internet of Things by microcontroller (4), the then long-range completion system wearer of radio frequency discrimination RFID module (2) authentication; Microcontroller (4) sends enabling signal to pulse producer, makes 1064nm impulse semiconductor seed laser emission single mode pulse seed laser, through signal optical fibre and optoisolator to pumping/signal bundling device (14); The semiconductor pump laser of pumping wavelength 915nm (9) sends the 915nm pumping laser and also arrives pumping/signal bundling device (14) through pumping optical fiber and pumping protection wave filter, seed laser and pumping laser enter through pumping/signal bundling device (14) mixes ytterbium silica fibre amplifier, exports high power 1064nm pulsed infrared laser light to exporting optoisolator after Yb dosed optical fiber amplifies; The tissues such as system wearer's hair nail are placed on the support, after the high power 1064nm pulsed infrared laser light that is produced by small-sized pulse optical fiber system hits, plasma based on the generation of Laser-induced Breakdown Spectroscopy effect, entered micro electronmechanical mems grating spectrograph (23) through fiber coupler by the fixing optical fiber collection of an end, the plasma resonance signal is through miniature self aggregation concave surface blazed grating diffraction, produce the Laser-induced Breakdown Spectroscopy signal, when microcontroller (4) sends enabling signal to pulse producer, enabling signal is through digital delay pulse producer DG535(28) produce the delaying time to CCD Drive and Control Circuit (27) of a microsecond magnitude, to start line array CCD exposure Laser-induced Breakdown Spectroscopy signal, this Laser-induced Breakdown Spectroscopy signal deposits first the CCD output state in, then Laser-induced Breakdown Spectroscopy signal to the Internet of Things server expert system that is sent in the CCD output state (29) by microcontroller (4) the purple honeybee ZigBee transceiver module of control (1) is carried out analyzing and diagnosing and storage, and can receive by purple honeybee ZigBee transceiver module (1) diagnostic result of expert system.
2. based on the signal analysis of Internet of Things Laser-induced Breakdown Spectroscopy and the transmission method of the described system of claim 1, it is characterized in that following steps:
1) behind microcontroller (4) control purple honeybee ZigBee transceiver module (1) the wireless connections Internet of Things, radio frequency discrimination RFID module (2) completion system wearer authentication;
2) after the wearer's of system the tissues (17) such as hair nail are hit by the high power 1064nm pulsed infrared laser light of small-sized pulse optical fiber system (18) generation, the plasma (20) that produces based on the Laser-induced Breakdown Spectroscopy effect is entered micro electronmechanical mems grating spectrograph (23) by optical fiber (22) collection, and the Laser-induced Breakdown Spectroscopy signal deposits first CCD output state (29) in;
3) send Laser-induced Breakdown Spectroscopy signal to Internet of Things server expert system by microcontroller (4) the purple honeybee ZigBee transceiver module of control (1) and carry out analyzing and diagnosing and storage, and can receive by purple honeybee ZigBee transceiver module (1) diagnostic result of expert system.
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| CN103512868B (en) * | 2013-09-10 | 2015-08-26 | 华中科技大学 | A kind of microcell laser probe analytical instrument based on fibre-optic waveguide |
| CZ2013771A3 (en) * | 2013-10-03 | 2014-07-23 | Vysoké Učení Technické V Brně | Modular device for remote chemical material analysis |
| CN104034703B (en) * | 2014-06-12 | 2016-07-06 | 中国科学院上海技术物理研究所 | The LIBS material composition detection system of the low detection limit of high s/n ratio improved and method |
| CN108072634A (en) * | 2016-11-15 | 2018-05-25 | 中国科学院光电研究院 | It is a kind of to survey child's hair to obtain the Laser induced plasma spectroscopy analytical equipment of micro- information |
| CN108074300A (en) * | 2016-11-15 | 2018-05-25 | 中国科学院光电研究院 | A kind of access control system using Laser induced plasma spectroscopy analytical equipment measurement nail ingredient |
| CN107907526B (en) * | 2017-10-13 | 2023-09-12 | 中国科学院上海技术物理研究所 | Deep space detection micro-region self-adaptive Raman fluorescence imaging combined system |
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| CN201429568Y (en) * | 2009-07-03 | 2010-03-24 | 广州市计量检测技术研究院 | Rapid detection device for multichannel laser induced breakdown spectroscopy |
| CN202230022U (en) * | 2011-07-06 | 2012-05-23 | 中国科学院上海技术物理研究所 | Mini-type internet-of-things laser induced breakdown spectroscopy medical sensor system |
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| US8319964B2 (en) * | 2009-07-10 | 2012-11-27 | University Of Florida Research Foundation, Inc. | Method and apparatus to laser ablation—laser induced breakdown spectroscopy |
| US8655807B2 (en) * | 2010-04-05 | 2014-02-18 | Applied Research Associates, Inc. | Methods for forming recognition algorithms for laser-induced breakdown spectroscopy |
| WO2011130804A1 (en) * | 2010-04-23 | 2011-10-27 | Datatrace Dna Pty Limited | System and method for establishing the integrity of items using laser induced breakdown spectroscopy |
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| CN201429568Y (en) * | 2009-07-03 | 2010-03-24 | 广州市计量检测技术研究院 | Rapid detection device for multichannel laser induced breakdown spectroscopy |
| CN202230022U (en) * | 2011-07-06 | 2012-05-23 | 中国科学院上海技术物理研究所 | Mini-type internet-of-things laser induced breakdown spectroscopy medical sensor system |
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