CN101480428A - Essence of olive leaf and cola nut, and use thereof - Google Patents
Essence of olive leaf and cola nut, and use thereof Download PDFInfo
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- CN101480428A CN101480428A CNA200810055691XA CN200810055691A CN101480428A CN 101480428 A CN101480428 A CN 101480428A CN A200810055691X A CNA200810055691X A CN A200810055691XA CN 200810055691 A CN200810055691 A CN 200810055691A CN 101480428 A CN101480428 A CN 101480428A
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Abstract
The invention relates to olive leaf and kola nut essence liquid and a purpose thereof. The olive leaf and kola nut essence liquid is prepared from the raw materials by weight: 70 to 80 percent of olive leaf extracting solution, and 30 to 20 percent of kola nut juice. The olive leaf and kola nut essence liquid has fatal interference effect in the synthetic process of amino acid used for keeping virus energy, stops virus infecting and propagating through killing virus or preventing viruses from diffusing, developing and aggregating in cell membranes, can directly penetrate through recipient cells infected by viruses so that viruses can not duplicate, can neutralize the generation capability of reverse transcriptase and protease so as to kill the material bases for the existence of retrovirus of HIV and the like and change the ribonucleic acid of healthy cells, can directly irritate phagocyte dissolution, helps time promptness of an immunologic system, swallows microorganisms and foreign substances, and has no harmful effect to the function of healthy cells. Normal people can enhance the capability of resisting various diseases, keep vigorous and have a healthy body when taking the olive leaf and kola nut essence liquid.
Description
Technical field
The present invention relates to a kind of olive leaf Rogor essence (OLGK) and uses thereof, this olive leaf Rogor essence can not only suppress virus and antibacterial, and can essence prevent growing of various viruses, can also kill those and be proved to be and have drug-fast virus.
Background technology
Antibiotic once was considered in the middle of the traditional medicine one of the most effective weapon, but along with these antibiotic a large amount of uses, and the appearance of various new unusual pathogenic bacterias, microorganism constantly strengthens for the resistance that medicine produced that we use, and those target microorganisms have slowly developed its Drug resistance.Although nearly more than 30 kinds of antibiotic have been arranged at present, there is not a kind of antibiotic to can do with the human various pathogenic bacterias that run into.
In decades, a variety of causes is promoting development of antibiotics, and nowadays the doctor is faced with a new difficult problem, antibacterial is mutation, and medicine has been had repellence, and these infective antibacterials have become virus, cause patient's death owing to the invasion of these viruses that can be cured in the past.Therefore, increasing fitness guru prophesy antibiotic has lost its effect gradually, and is facing the destiny that is eliminated, even prevailing bacterial infection of one day in future also may cause serious health problem.In order to solve the existing in prior technology problem, we are than whenever more needed a kind of natural, product safety, that have no side effect to resist the resistive pathogenic bacteria of immune system in the past.
Summary of the invention
The object of the present invention is to provide a kind of olive leaf Rogor essence (OLGK), this essence is extra quality, potent anti-virus formulation, it can not only suppress virus and antibacterial, and can essence prevent growing of various viruses, can also kill those and be proved to be and have drug-fast virus.
The objective of the invention is to be achieved through the following technical solutions: a kind of olive leaf Rogor essence (OLGK), it is to be prepared from by its weight ratio by following raw material:
Folium olive extracting solution 70-80
Cola natural juice 30-20.
Olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of hepatitis B medicine or treatment and prevention hepatitis B.
Olive leaf Rogor essence is used to improve the purposes of the nutrient and healthcare products of function of immune system medicine or treatment and epidemic prevention systemic disease.
Olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of cardiovascular disease medicine or treatment and angiocardiopathy preventing.
Olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of Peptic Ulcers or treatment and prevention Peptic Ulcers.
Olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of fibromyalgia medicine or treatment and prevention fibromyalgia.
Olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of respiratory tract disease or treatment and prevention respiratory tract disease.
Olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of sexually transmitted disease (STD) medicine or treatment and prevention of STD.
Olive leaf Rogor essence of the present invention (OLGK) has been compared following advantage with the antibiotic of prior art:
1. the amino acid whose building-up process that keeps viral vigor there is fatal interference effect;
By kill live virus or prevent the diffusion of virus in cell membrane, grow, accumulative infection and the propagation that is used for preventing virus;
3. directly penetrating by the recipient cell of viral infection to duplicate virus;
4. the material base that the generative capacity of converse transcriptase and protease of neutralizing is depended on for existence with the retrovirus of eliminating HIV and so on changes the ribonucleic acid of healthy cell;
5. directly stimulate phagocytolysis, help immune system in time to react, engulf those microorganisms and foreign substance; Experiment is proof also, and the olive leaf Rogor essence that the present invention has a potent antibacterial sterilization effect without any harmful effect, does not have toxicity, even large dose oral administration also is safe to the function of healthy cell;
6. the normal person takes the ability that olive leaf Rogor essence of the present invention can strengthen the multiple disease of opposing, keeps energetic, healthy.
The specific embodiment
Below in conjunction with embodiment the present invention is made a detailed description.
Embodiment 1:
A kind of olive leaf Rogor essence, it is to be prepared from by its weight ratio by following raw material:
Folium olive extracting solution 70-80
Cola natural juice 30-20.
In the present embodiment, it can be prepared from by its weight ratio by following raw material:
Folium olive extracting solution 78
Cola natural juice 22.
In the present invention, the Folium olive extracting solution is to extract from the leaf of olive tree, and its Main Ingredients and Appearance is a cleupin.Cleupin is a kind of active ingredient, and it has powerful bacteria resistance, antiviral property and oxidation resistance; Have the growth that stops cell and virus, and the activity of important cells in the stimulating immune system, infect with opposing; Have oxidation resistance, can alleviate the degree of oxidation of low density lipoprotein, LDL, prevention coronary heart disease, atherosclerotic generation; Has the vascular smooth muscle of releiving, the ability that brings high blood pressure down.Have the protection Skin Cell and be not subjected to ultraviolet injury; prevent the decomposition of ultraviolet to the skin membrane lipid; promote fibrocyte to generate collagen protein; reduce the secretion of fibrocyte glue unit enzyme; stop the anti-polysaccharide reaction of cell membrane; thereby highly protect fibrocyte, reach and keep the tender and elastic effect of skin.
Cola (have another name called bitter laughable) is the fruit of a kind of Jia Xiniya Cola, originates in the ground such as Africa, the West Indies, Brazil of tropical rainy climate.About 12 meters of the laughable height of trees, cola juice can be used for the preparation of antimicrobial drug and antiparasitic, and the seed of cola can be used for treating bronchitis, pharyngeal infection, liver adjusting etc.The contained composition of cola comprises two flavonoid, ton ketone, benzophenone, flavanone etc., and wherein benzophenone, flavanone have very strong anti-inflammatory, antibiotic and ntiviral characteristic, can also prevent and treat diabetes and suppress hepatotoxic activity.In Africa, usually directly edible cola of people and seed thereof, and use it for medical material among the people, with nourishing and fit keeping function with as antidote.
A kind of preparation method of olive leaf Rogor essence,
A. with the Folium olive roguing of plucking, the clear water rinsing, implantation concentration is the chlorine dioxide of 100PPM then, and activated processing sterilization; Treated Folium olive is carried out aeration-drying under lucifuge, 25-35 degree conditions handle; Be that solvent carries out secondary back with exsiccant Folium olive and extracts with 50% methanol of 10 times of volumes again; Extracting solution is carried out the vacuum decompression concentration, and in concentrated solution, add antioxidant-tea polyphenols (water solublity), obtain spissated Folium olive extracting solution;
B. cola is washed with clear water, broken juice, expressed fruit juice is heated to 80-95 ℃ of enzyme denaturing, fast cooling to 45-48 ℃, add 0.01-0.012% and 0.003-0.004% pectase and amylase of fruit juice weight respectively, carry out enzymolysis, fully Declot fruit natural juice after the fruit juice filtration after the degraded, the degerming;
C. the cola natural juice that spissated Folium olive extracting solution that step a is obtained and step b obtain is mixed by its weight ratio and is promptly obtained olive leaf Rogor essence.
Olive leaf Rogor essence of the present invention also can be prepared into the powdery capsule, and preparation method is as follows:
A. with the Folium olive roguing of plucking, the clear water rinsing, implantation concentration is the chlorine dioxide of 100PPM then, and activated processing sterilization; Treated Folium olive is carried out aeration-drying under lucifuge, 25-35 degree conditions handle; Be that solvent carries out secondary back with exsiccant Folium olive and extracts with 50% methanol of 10 times of volumes again; Extracting solution is carried out the vacuum decompression concentration, and in concentrated solution, add antioxidant-tea polyphenols (water solublity), obtain the powder of Folium olive extracting solution through lyophilization or spray drying;
With the powder of producing 1 kilogram of Folium olive extracting solution is example:
With the roguing of 70kg Folium olive, the clear water rinsing, implantation concentration is that the chlorine dioxide of 100PPM carries out the activation processing sterilization then; Treated Folium olive is carried out aeration-drying under lucifuge, 25-35 degree conditions handle; 10 times of volume 50% methanol of reuse are that solvent carries out the secondary back extraction with exsiccant Folium olive, extracting solution is carried out the vacuum decompression concentration, and in concentrated solution, add antioxidant-tea polyphenols (water solublity) 50-200PPM, get 1 kilogram of the powder of Folium olive extracting solution through lyophilization.
With the powder of producing 1.5 kilograms of Folium olive extracting solution is example:
With the roguing of 70kg Folium olive, the clear water rinsing, implantation concentration is that the chlorine dioxide of 100PPM carries out the activation processing sterilization then; Treated Folium olive is carried out aeration-drying under lucifuge, 25-35 degree conditions handle; 10-15 times of volumes of reuse, 50% methanol is that solvent carries out the secondary back extraction with exsiccant Folium olive, extracting solution is carried out the vacuum decompression concentration, and in concentrated solution, add antioxidant-tea polyphenols (water solublity) 50-200PPM, spray-dried (adding excipient in case of necessity) 1.5 kilograms of the powders of Folium olive extracting solution.Described excipient can be a powder-beta-dextrin.
B. cola is washed with clear water, broken juice, expressed fruit juice is heated to 80-95 ℃ of enzyme denaturing, fast cooling to 45-48 ℃, add 0.01-0.012% and 0.003-0.004% pectase and amylase of fruit juice weight respectively, carry out enzymolysis, fully Declot fruit natural juice after the fruit juice filtration after the degraded, the degerming obtains cola natural juice powder with the processing of cola natural juice drying;
C. the cola natural juice powder that obtains of the powder of the Folium olive extracting solution that step a is obtained and step b mixes by its weight ratio and is prepared into capsule and promptly obtains olive leaf Rogor essence powdery capsule.
Contain gluconic acid from chemically say cleupin (Oleuropein), its hydrolysate comprises likes promise hydrochlorate (elenolate), and it is to produce opposing aspergillosis (Asperqillus) and other lactobacter growth reactive activity material.
One. to like that promise acid calcium (calcium elenolate) is the safety evaluatio that example is liked promise hydrochlorate (elenolate):
With liking promise acid calcium (calcium elenolate) when mouse is carried out toxotest, if by median lethal dose(LD 50) LD50 administration, so each medicine feed dosage roughly is to adopt kg body weight clothes 1.7 to restrain the ratio of agent.If the oral dose of every day connects and fed 30 days in the ratio of per kilogram of body weight 0.03 gram, 0.1 gram, 0.3 gram, concerning experimental mouse all be in the safety range of more easily bearing so.Equally,, for experimental dogs, also more easily bear, after adopting maximum dose level, can produce slight allergy according to dosage like this.
Test material of the present invention and method:
1, single agent test:
1) be that 0.1-log gives five male and five female CARWORTH CF-1 Mus (each 20 grammes per square metre, lumbar injection love promise acid calcium aqueous solutions at interval by statistics.2) in addition to 150 the gram body weight five rats (the special anosis SPF rat of general strong SPRAGUE-DAWLEY) administration in a similar manner.3) press the at interval oral love promise acid of 0.2-log calcium in addition five male rats.
All observed seven days for every group, all animals all survive.LD50 (median lethal dose(LD 50)) calculates according to the Spearman-Karber method.
2, subacute oral test:
1) give each 10 SPF Mus of male and female by each oral 0 milligram of a kg body weight one day, 30 milligrams, 100 milligrams, 300 milligrams love promise acid calcium was taken one month continuously.
2) feed to like promise acid calcium, respectively according to 3 milligrams, 10 milligrams, 30 milligrams/kg body weight/day, one month for each two of the female male beagles of seven months sizes totally.
Off-test, the hematological examination of surveying each SPF Mus.Identify with hematology, urinalysis and the clinical chemistry of every the dog in back before testing that pathological tissue inspection (comprising naked eyes cardinal principle and microscopically) has all been done inspection to each Mus and dog.
3, the intranasal test:
1) original experimentation: the prosperous chicken in the Rec of giving one-year-old age every day three times, give the collunarium of 1% love promise acid calcium aqueous solution, different at interval respectively natural law administrations, totally 14 days.Clinical observation every day is dissected at last and is checked concha nasalis and paranasal sinus and main viscera tissue inspection.
2) further test: with new zealand rabbit with 0.1%, 0.25%, the aqueous solution of 1% love promise acid calcium, nose spraying every day three times, totally 2 days.Do the test of further drug resistance then,, the highlyest continue a week and two weeks with 0.6% with different concentration administrations, dosage be 0.2 milliliter/spray medicine, four times a day at every turn.Do after death tissue examination concha nasalis, paranasal sinus (chamber) and major organs at last.
The result:
1, single agent test: about LD50 (median lethal dose(LD 50))
1) mice is 120 a milligrams/kg body weight, intraperitoneal injection
2) rat is 160 milligrams/kg body weight (intraperitoneal injection), 1700 milligrams/kg body weight (oral)
2, subacute oral test:
1) rat group: all existence after the administration in month of all rats.Unique pathological change relevant with this medicine is: give to have in the rat of 200 milligrams/kg body weight/day of maximum amount at 20 to occur macroscopic non-property macula lutea on eight Mus gastric mucosas, but the no abnormal change of microscopically histological examination.
2) beagle group: administration is after one month, and only having in four dogs of animal of maximum dose level (30 milligrams/kg body weight) has three to produce slight accidental vomitings and the shallow degree erosion of minority gastric mucosa.
3, the nasal administration test:
1) chicken group: after the administration in two days, visible chicken watery nasal discharge, tissue examination sees that mucous epithelium has flat sample to change, idol has a little rotten to the corn and macula lutea cellular infiltration.More than change and only appear at the high concentration group.And olfactory epithelium sensitivity is more obvious than respiratory tract.
2) rabbit group: above-mentioned same variation comes across high concentration 1% spray delivery, and the no change of 0.1% and 0.25% concentration.
In further testing: 0.1%, 0.3%, 0.6% concentration, the spray medicine was four times in one day, divided 7 days and two groups test in 14 days.Every group of five rabbits were measured under different concentration and time, and the result is as follows:
A, 0.1% and 0.3% concentration medication each 7 days does not have obviously difference, does not have significant difference with matched group yet.Have only and a little mucosal inflammation phenomenon occurs.
With 0.6% concentration spray nose, then there is mild inflammation to stimulate, there are a little olfactory epithelium infringement and your pupil's shape cell to occur.
B, fortnight group: 0.1% concentration group and matched group no significant difference.But 0.3% and 0.6% concentration spray nose had the slight moderate nose that arrives to stimulate after 14 days, and epithelium also has variations such as flat cavity, than 7 days groups obviously, mainly appears at olfactory epithelium.
Safety evaluatio:
1. animal test results can be used as the prediction and the reference of human body.Above-mentioned test illustrates systemic effects or almost is free from side effects.
2. the zest of spray nasal administration changes when mainly appearing at high concentration, especially to the olfactory epithelium cell.
Nosepiece structure and the people of rabbit exactly like, and olfactory epithelium is mainly in superior nasal concha or nasal cavity back upper place, and is different with chicken.Therefore stimulation there is not chicken extensive yet.The body protective reaction appears being actually in your pupil's shape cell, but not irritant reaction.The nasal cavity area of considering the people is big, and people's nose is lower than animal to the sensitivity that stimulates, and should think safe.We think if the concentration of liking promise acid calcium spray nose is placed between 0.0085-2%, especially 1%, and four administrations every day, continuous 14 days is receptible fully.
Two. to like that promise acid calcium (calcium elenolate) is the antiviral efficacy evaluation that example is liked promise hydrochlorate (elenolate):
The extracorporeal antivirus effect activity of liking promise acid calcium aqueous solution has reflected on one's body the rat that has infected parainfluenza 3.This medicament has just become disinfectant within viral a few minutes having inoculated.Like that promise acid calcium has also shown its therapeutic effect simultaneously after infecting 8 hours.After infection was stable, this antiviral activity reduced the order of severity of the infection of virus.The minimum effective dose of liking promise acid calcium only can produce small tissue on the olfactory epithelium of the sensitivity of rat changes, but can produce important curative antiviral activity.This effect that obtains shows, likes the virus composition of the cell that produces in that promise acid calcium can influence self or the virus relevant with cell.In the process of research antiviral drugs, find to like that promise acid calcium has the extracorporeal antivirus effect activity for some viruses, comprise several people's common cold virus.As a kind of extracorporeal antivirus effect medicine of potentialization, like that promise acid calcium has carried out the imitation test in parainfluenza 3 viral infection of rat.These tests all are that infection, the therapeutic process of the common cold of imitation human volunteer carries out.
Material of this experiment and method: animal: the gold of 100 grammes per square metres that obtain from Lakeview Hamster Colony is chatted the inferior rat of periodical.Need with 10 rats in the great majority test.These rats all are that per five passes are in a cage.
Virus: these virus spreads, just the myxovirus parainfluenza 3, obtain from American Type Culture Collection, and these viruses all are kept in the infected HEP-2 frozen cell culture pond.Have only concentration to be higher than 10
7The dental plaque culture pond that forms every milliliter of unit just can be used for infected rats.
Virus inoculation: not dopey rat by grafting in 0.01 milliliter Hank ' s balanced salt aqueous solution 10
4To 4 * 10
4The HA of PFU-1 virus.The syringe virus inoculation that adheres to 0.25 milliliter of pin that has 27 bores in this sub-fraction is in right nasal cavity.This syringe is operated by microsplitter, and a fritter plastic tube is arranged on the syringe needle.
Dispenser: the rat medicament and the placebo treatment that give not anaesthetize, impose on every nasal cavity inwall by each 0.05 milliliter.
Nasal passage is cleaned: the sampling of infected nasal cavity is by back 3 hours nasal cavity cleanings of last treatment or 24 or 32 hours postoperative infections: in both cases, about 3 to 4 milliliters BSS liquid is filled into a side nasal cavity by force, nasal douche is collected from the opposite side nasal cavity, and these nasal douche of collecting are rapidly frozen before use.
The titration of virus method: the titration of virus of nasal douche is to carry out in the culture fluid double-layer of HEP-2 cell, and the plaque number carried out after 48 to 72 hours.
Result and discussion:
Preparation: in order to obtain to have carried out many preparatory tests about the vitro characteristics of medicament.With the control group of brine treatment relatively, before nearly 3 hours of virus inoculation with loving the not process of influence infection of multiple treatment that promise acid calcium carries out.The treatment of metainfective 2 hours or 18 hours does not have antiviral efficacy yet.These observed results show that it is active to make medicament bring into play its contact, and treatment must be carried out in the time near virus inoculation.Be dispersed in 24 hours virus in the postoperative infection nasal douche to a certain degree minimizing is all arranged under preceding 15 minutes of inoculation or back 15 minutes treatment, and be the treatment of virus before or after inoculation to a greater extent, interval before and after the infection time is dropped to 10 minutes from 15 minutes drop to 5 minutes again, can improve the effect of liking promise acid.These discoveries conform to the external activity of medicament.
The interval of shortening virus inoculation and effectively implementing between the treatment is that the medicament in the rat nasal passage can disappear very soon.Within with 15 minutes after the treatment of the love promise of 2% concentration acid calcium, being less than 5% medicament can recover from the nasal douche of rat and Cavia porcellus.Found evidence explanation, liked the very fast and protein bound of promise acid calcium, Here it is why it can be as free medicament very fast reason from the nasal cavity disappearance.
The external virus killing effect of infection period: this test in, 25 rats are treated with the medicine in the saline of 2% concentration, other 24 with saline as placebo.In 0.01 milliliter BSS of inoculation preceding 10 minutes or back 10 minutes of the HA-1 virus of 10-PFU, these two groups of portions were bestowed 0.05 milliliter in every nasal cavity.Nasal cavity cleaning carried out in infection in back 24 hours, and viral content is decided by bacteriolyze speckle analytic process in the Hep-2 cell dish.The rapid reduction of viral load has shown the effectiveness of the minimizing virus distribution of liking promise acid calcium in the animal nasal douche of with medicament treatment: data analysis shows that the difference of placebo group and medicament group is very big.In order further to determine the antiviral property of medicament, determine virus to spread to the speed of lung.From every treated animal, chose 10 wantonly in back 72 hours in infection.The pulmonary of 10 animals that virus is treated in the placebo smelting again is found again, but the pulmonary the animal of pharmaceutical treatment is not found: so great difference has shown one effectively in the inactivity of nasal cavity virus, has stoped the propagation of virus to pulmonary.This active effect is interrupted because of original position (insitu) the virus killing activity of medicament, and this medicament had effectively reduced the number of infectious particles before they penetrate into susceptible cell.If situation is really so talked about, this medicament can exert an influence to the new cell that produces from the cell of initial infection equally, thereby stops or reduce the focus number of superinfection.
Virus killing effect after eclipse phase.For judging that medicament can or can not influence the virus of new formation, 100 rats are divided into 10 groups as previously mentioned by virus inoculation, and like the treatment of promise acid calcium with the saline of intranasal saline or 1%.These rats are bestowed 0.05 milliliter of every nose one to five time, 8 hours begin to treat after infecting, once repeated in 2 hours in a small amount in a small amount or at interval, be up to and infected back 16 hours, the recovery for the treatment of back 3 hours virus at last all reduced significantly, the intranasal virus of cleaning is dropped down and reflected a persistent antiviral efficacy surely for the second time.The quantity of experimental animal, persistent effect and result's concordance show clearly that all medicament is reducing the virus spread granule and reducing therapeutic value aspect the infectiousness.
Least effective dose (LED): the animal for the treatment of with 0.25% liquid medicine continues to demonstrate than the control group obviously lacks output virus.Even in the middle of the animal of those 0.1% concentration solution treatments, the minimizing of virus also is significant.Least effective dose (LED) is estimated lower than what test, if particularly use multiple test.
Least effective dose (LED) in the multiple test.Keep punching and in enough therapys, determine a least effective dose (LED).In next one test, infect beginning in back 8 hours, be applied with six treatments of graduate drug concentration, every interval 4 hours once, treating for the last time is in infection back 28 hours, the result shows that the sour calcium of the love promise of 0.075% concentration has significant effect.As if this be exactly least effective dose (LED).
Medicine is to the influence of rat nasal cavity tissue.The organum olfactorium epithelial tissue of rat had had the outstanding sensitivity of quite a lot of medicine have been reported.May be because the size in the olfactory sensation zone of rat and complexity and its residing position in nasal cavity make this tissue become the main target that stimulus object is positioned over nasal cavity.Going containing in the nose that love promise acid calcium solution more than 0.5% is expelled to rat, mainly is exactly the organum olfactorium epithelium that has changed it.Ciliate nose is to be affected in the junction of nasal bone mostly.But when the drug concentration reduction, this change will reduce.When arriving minimum effective drug concentration, change very small.Though at experimental animal (or even human body), the tissue injury of less degree or stimulation meeting are stood because of the minimizing of certain disease, but, organize at nasal cavity to obtain antiviral effect under the situation that does not almost have change in organization and have actual importance.
In the described here test, love promise acid calcium has demonstrated the rat of injecting the HA-I virus inoculation has been had the virus killing effect.In the treatment that after infecting 8 hours, begins to carry out, like that promise acid calcium still demonstrates its therapeutic effect.No matter be dose or at largest interval be 28 hours repeated doses.This effect by inoculation back early in 11 hours or the nasal douche collected in late 32 hours the remarkable minimizing of viral load proved, in case the thoughts hair dyeing is given birth to, this antiviral effect causes the continuation reduction of course of infection and is reduced to the infection speed of surrounding minimum: obtaining of this lasting effect shows that love promise acid calcium can influence the cell component in free or relevant with cell virus.The organum olfactorium epithelium of rat (and other experimental animals) is not although be mainly used in the infection of myxovirus, and is in general all very responsive to medicine.But 0.075% this minimum effective drug concentration of liking promise acid calcium can be used 6 treatments in back 28 hours in infection, only produces the minimum organization variation and is created in the antiviral therapeutic effect that seems very great on the data.Lack and show the adhering to of antiviral drugs that is subjected to tissue bound with permeating to be bestowed before 15 minutes to treat in inoculation by its relative inactivity.The effect that lacks the iuntercellular virus replication is by back 2 hours of inoculation, eclipse phase begin use the inactivity that is shown and show.But, when new virus appears in the infected cells, the medicine of using after eclipse phase can cause the minimizing of nasal cavity virus, at this moment, if medicament has been bound in infected virocyte surface, emerging virus meeting is brought the cellular material that is changed by medicine among its cell, make new virus not have an infectiousness, the virus that the proof that rapidly disappears of medicament is observed in the rat nasal douche reduce be not since in the nasal douche free drug external activity of residual components caused.This medicine seemingly produces its antiviral activity by the virus composition that influences the cell source.
Olive leaf Rogor essence (OLGK) is the compound preparation of Folium olive elite, and the novel uniqueness on composition of raw materials, processing technology has been strengthened the antimicrobial multi-functional mechanism of the original virus killing of Folium olive elite significantly.Except parent-cleupin (Oleuropein) essence that is full of the wide spectrum calcium salt-love promise acid that to resist all kinds of diseases that directly or indirectly cause by virus, antibacterial and protozoon, also added the very strong Ibo that effectively to suppress to cause harm and drawn the composition that extract in the laughable berry of virus, made the effective ingredient of olive leaf Rogor essence and virus killing effect improve about 2/3rds than common Folium olive elite.Olive leaf Rogor essence of the present invention can be referred to as the medical herbs antibiotic.
We are that 500 routine patients have carried out a clinical experiment.We recommend the patient to the capsule that olive leaf Rogor essence is made, and every day 3 times, each 2, will eat 6 capsules in one day.”
Each capsule all contains 500 milligrams of pure natural extracts.When our patient's symptom alleviates to some extent, begin to reduce dose every day, change 4 of every days into.The patient who is done experiment reacts well, effectively resists various antibacterials, virus, fungus, yeast, though there is not the patient to use it to come parasiticide, finds to parasite it is effective.As: tonsillitis (torsilitis), pharyngitis (pharangitis) and tracheitis, to the stomach that is caused by helicobacter pylori (Helicobacter Pylori), the duodenal ulcer curative effect is also fine.In addition, it is remarkable as the herpes effect to viral disease.
Clinical observation on the therapeutic effect of the present invention:
Participate in the patient characteristic table 1 of clinical experiment
| Sex: | Age: | 10～20 years old | 20～30 years old | 30～40 years old | 40～50 years old | More than 50 years old | Amount to |
| 58% women | 42% male | 12 | 117 | 143 | 181 | 47 | 500 |
This clinical trial is primarily aimed at all kinds of diseases that caused by pathologic biologies such as virus, antibacterial and mycetes: respiratory tract disease, amygdala inflammation, pharyngolaryngitis, tracheitis etc.; Pulmonary disease is as pneumonia, pulmonary tuberculosis, bronchitis etc.; Dental disorder is as pulpitis, leukoplakia, oral inflammation etc.; Dermatosis is as herpes and other viral dermatitis etc.; Bacterial skin infection is as pyoderma, trauma infection contamination etc.; Peptic Ulcers belongs to infection etc. as helicobacter pylori; And human immune system's aspects is to the reaction of olive leaf elite.It is as follows that clinical effectiveness is summed up brief introduction:
Table 2
| Kinds of Diseases | Clinical number | The recovery from illness number | The improvement number | Do not change | Sb.'s illness took a turn for the worse |
| Respiratory tract disease | 119 | 115 | 4 | 0 | 0 |
| Pulmonary disease | 45 | 42 | 3 | 0 | 0 |
| Dental disorder | 67 | 60 | 5 | 2 | 0 |
| Viral dermatosis | 172 | 120 | 52 | 0 | 0 |
| Bacillary dermatosis | 37 | 30 | 7 | 0 | 0 |
| Peptic Ulcers | 17 | 0 | 17 | 0 | 0 |
| Immune system | 43 | No standard | 40 | 3 | 0 |
By above result, clinical conclusion is as follows:
1,, the effective percentage of viral disease bacillary to all, cure rate reach 98%;
2, all immunity of participating in the patient of this clinical experiment are all strengthened to some extent;
3, comprise child and the teenager that participates in clinical experiment, side effect does not take place.
Embodiment 2: olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of hepatitis B medicine or treatment and prevention hepatitis B.
Clinical demonstration, olive leaf Rogor essence is for the hepatitis B great three positive obvious curative effects of having turned out cloudy, and the fastest only two weeks takes effect, and some people is only once can obtain recovery from illness by two months.
Mr. Xu, 28 years old, hepatopathy was unfortunately suffered from the tired and frequent dinner party because the contact business of going out is hurried back and forth throughout the year, checks through the attached infectious hospital of certain medical college and finds that liver function is undesired, is great three positive.Through hospital admission for isolation after two months, liver function recovery is normal, but still great three positive is arranged.Left hospital first day, the U.S. relative that just come back home have just sent one bottle of his oneself curing the disease olive leaf Rogor essence (OLGK) of toxicity flu.This is the oral drop of liquid.According to taking requirement, before having a meal every morning, drip 25 (being equivalent to 1ml) olive leaf Rogor essences under tongue, suck about one minute, swallow then; Before the sleep in evening, also drip 25 olive leaf Rogor essences under tongue, contain for a moment and swallow again.Certainly, also taking the medicine that protects the liver that the Shi doctor that leaves hospital opens simultaneously.Through after one month take, through examination in hospital, great three positive is turned out cloudy.Because work tired and having drunk ordered wine, have an index to return the positive again second middle of the month after leaving hospital, still adhere to taking olive leaf Rogor essence after one month that positive index turned out cloudy again.Take 6 bottles continuously, consolidate curative effect, it is negative that from then on all kinds of indexs keep always, up to now not recurrence.Mr. Xu marries and gives birth to babies, whole family's health.
Mr. Zhang, 29 years old, a health check-up was though find that liver function is normal, has great three positive.Because premorbid has been reserved during the Spring Festival after half a year and has been married, so very worried.Seek medical advice and medicine everywhere.Take olive leaf Rogor essence and obtain turn out cloudy good ward mate's of imitating recommendation of great three positive through having, ask someone to have bought several bottles of olive leaf Rogor essences to the U.S.'s strong source biological engineering company limited.By morning every day, evening each 25 (being equivalent to 1ml), the method for sublingual administration.During health check-up find once more that less than three months great three positive has changeed small three positive.So continue to take olive leaf Rogor essence again to consolidate curative effect.Find during to premarital checkup that physical condition meets requirements for marriage, happiness is stepped into the auditorium of marriage finally.Now got married and given birth to son, not recurrence.
Mr. Gao, 58 years old, the liver cirrhosis state of an illness was heavier, supported one's family by oral medicine and injection medicine originally.After take the ward mate's of olive leaf Rogor essence recovery from illness hepatopathy recommendation, also begin to take, but escalated dose slightly, every day is early, evening is on an empty stomach at 35 (being equivalent to 1.4ml) olive leaves of sublingual administration Rogor essence.After two months, health check-up discovery liver function is recovered to some extent, has a meal with spiritual all than very big improvement was arranged in the past.So doctor's suggestion is only taken medicine, and does not have an injection, and continues to take olive leaf Rogor essence and keeps.
Mr. Wang, 21 years old, rise up into university before, be in because of uncomfortable, find that on inspection liver function is undesired, be great three positive.Have very big improvement by taking medicine and beating islets of langerhans, checked afterwards to have transferred small three positive to, liver function is normal.Through behind the some months, find uncomfortablely again, be again great three positive on inspection.Known olive leaf Rogor essence of the present invention (OLGK) through ward mate's introduction, just do not had an injection that olive leaf Rogor essence is taken in the light medication simultaneously, every day is 25 of each sublingual administrations (being equivalent to 1ml) sooner or later.Health check-up is after two months found: great three positive has changeed small three positive, and liver function recovery is normal, so continue to take olive leaf Rogor essence.Present healthy recovery is normal.
Embodiment 3: olive leaf Rogor essence is used to improve the purposes of the nutrient and healthcare products of function of immune system medicine or treatment and epidemic prevention systemic disease:
Olive leaf Rogor essence of the present invention can effectively stop the various diseases that caused by virus, antibacterial etc., as flu and other virus disease, various funguses, mycete, saccharomycetic infringement, bacterial infection, the olive leaf Rogor essence of use sufficient dosage can disperse the infringement to human body and animal of disease worm and other parasite, with the process of all kinds of diseases trial of strength in, olive leaf Rogor essence can not only prevent, and also provides safer, effectively treatment.
The bactericidal effect of olive leaf Rogor essence of the present invention sees Table 3:
Table 3
| Microorganism (organisms) | Initial concentration | Time started (1-2 hour) | 7 days | 14 days | 28 days |
| Aspergillus niger (Aspergillus niger) | 19750 | 6900 | 0 | 0 | 0 |
| Candidiasis (Candida albicans) | 12750 | 100 | 0 | 0 | 0 |
| Escherichia coli (Escherichia coli) | 402500 | 100 | 0 | 0 | 0 |
| Pseudomonas aeruginosa (Pseudomonas aeruginosa) | 765000 | 100 | 0 | 0 | 0 |
| Staphylococcus aureus (Staphylococcus aureus) | 515000 | 50 | 0 | 0 | 0 |
By table as seen, olive leaf Rogor essence greatly reduces the concentration of implanting the microorganism in the culture medium.
Mrs Shi, 49 years old.Before 15 years, fall ill because of allergy and pneumonia, then encroached on by the infection that is comprehensively formed by a lot of antibacterials again, these antibacterials comprise:
Lyme arthritis (Lyme disease), retrovirus (The Spuma form of retrovirus), tularemia (Tularemia), pseudomonas (Psendemonas) etc.
Lyme arthrosis (Lyme disease) is generally propagated by louse, can cause the infection and the development in one or more joint;
Retrovirus (The Spuma form of retrovirus) is also referred to as " foamy " virus, it shows as obstinate, and physical weakness is similar to the symptom of influenza, the spitting image of confirmed fatigue, the confirmed fatigue of saying so more accurately, immunologic function are represented syndrome;
Tularemia (Tularemia) is a kind of animal infectious disease on one's body that occurs in, show that human body then is immune apolipsis, this disease is by the insecticide carrier or directly contact is propagated, and symptom mainly shows as fever, headache, lymph node inflammation and has skin pain, ocular infection, stomachache etc.;
Pseudomonas is present in urethra, ear, just can invade and harass patient when people's immunocompetence descends, and the common antibiotic of this infection can not effectively be treated, and need wash with 1% acetic acid.
The picture table tennis of patient's the enlargement of lymph node is so big, contains a large amount of toxin, for many years, oneself has tried many other methods, as: the homeopathic therapeutic method, the spice wet goods, but the effect of these therapies is all general.She bites on and strengthens the immunocompetence of oneself, and the very lucky people of having advises that she uses olive leaf Rogor essence powdery capsule.Take two capsules every day during beginning, changed each 1 afterwards into, every day 3 times, continued to have taken three weeks after, find that disease has had to alleviate, last, each 2, every day 3 times and adhere to this intake and obtain useful effect.Since having used product of the present invention after five months, confirmed fatigue and the function of immune system forfeiture malaise symptoms that syndrome brought have all disappeared, as if health is good now, is not subjected to the puzzlement that antibacterial, virus, parasite etc. bring again, and the people has also youthened.
Olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of chronic fatigue syndrome medicament or treatment and prevention chronic fatigue syndrome.
The reason that causes chronic fatigue syndrome: confirmed fatigue acquired immunodeficiency syndrome patient almost is subjected to some kind infection by microorganisms bar none.These microorganisms may comprise herpesvirus, certain yeast or certain parasite.When the mankind are in immunosuppressant period, they were just availed oneself of the opportunity to get in when resistance descended.
Chronic fatigue syndrome patient usually is subjected to the saccharomycetic invasion of white beads of excessive breeding.Usually contain protozoacide in this parasite, also contain parasite (generally being blood sucker) sometimes.But the viral infectious relevant with the confirmed fatigue acquired immunodeficiency syndrome consumes patient's muscle power and energy mostly.A lot of Olive leaf P.Es that actively use are treated the confirmed fatigue acquired immunodeficiency syndrome and are followed disease---and the medical circle personage of fibromyalgia is verified, and this disease is because one or more viruses---modal is herpesvirus---invasion human body is caused.Olive leaf Rogor essence or its powdery capsule all have better curative effect to treatment fibromyalgia and chronic fatigue syndrome.
Miss Tan 22 years old, just graduates from school.She showed the symptom of similar influenza at that time---throat pain, cough, fever, myalgia and weakness.She changes full of life and energy on ordinary days appearance, becomes sickly-looking, suffers from chronic fatigue syndrome on inspection.When beginning to take olive leaf Rogor essence powdery capsule, every day 4 times, each 3, she feels sometimes hot and sometimes cold, and dripping sweat is weak all over, dog-tired, also show the symptom that a lot of other state of an illness increase the weight of, even " death " reaction is arranged, this is because medicine is being killed those viruses, antibacterial, fungus and other parasite.But by the 3rd day later, she is suddenly from all not moderate having freed, and muscle power also strengthens greatly.She regains one's vigor several months, still full of physical strength energetic till now.
Embodiment 4: olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of cardiovascular disease medicine or treatment and angiocardiopathy preventing.
The composition of olive leaf Rogor essence can be eliminated ventricular fibrillation (arrhythmia).
Mr. Ren, 61 years old, suffer from ventricular fibrillation for 2 years, always feel uncomfortable in chest, asthma, physical weakness, the total material of antiangiogenic therapy helps very little to him.Take olive leaf Rogor essence powdery capsule through suggestion, after three weeks, just can do some muscular labor 2 of every days, can also walk for a long time, those former symptoms have all disappeared.
Woman with a hypoplastic vagina scholar, 53 years old, owing to suffer from the early retirement of having to of coronary heart disease, tracheitis, chronic arthritis and shank neural paralysis, she has experienced following operation: a place is the three root cap shape arteries and veins blood vessels that connect heart, another place is the femoral artery blood vessel of left lower limb and right lower limb, but the operation role is very little, and she still can't be movable with intermittent angina pectoris and long-time both legs.Angina pectoris also can cause the pain of left limb with the cardiovascular hardening owing to the heart anoxia causes, feels it is dyspnea to the people, and possibility at once will be in the dust.Anginal morbidity with overtired, excited, severe cold is relevant.Periodic inconvenient activity is that local blood circulation does not freely cause, often causes shank pain, cramp.Pain will occur when walking, and symptom just alleviates during rest, the use lower limb that the patient can only be limited.
Through suggestion, she has taken olive leaf Rogor essence powdery capsule, has just begun only to take one every day, take a favorable turn in order to make knee arthritis, and she begins to increase consumption, changes 2 of every days into.Its symptom has been clearly better, and the symptom that has has thoroughly disappeared.One week of angina pectoris in the past will fall ill several times, has to contain below tongue nitroglycerin sometimes.After having taken olive leaf Rogor essence powdery capsule, no longer needed nitroglycerin.As for her shank symptom, the distance in the building, a building of passing by in the past all is very difficult, walks one kilometer road continuously and can have a rest now.
Embodiment 5: olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of Peptic Ulcers or treatment and prevention Peptic Ulcers.
Ulcer of digestive system is that digestive tract endocrine mucus and body of gland break, can't treat, and with infection.Olive leaf Rogor essence composition can play the searching free radical, and prevents the effect of super oxidation reaction, can be applicable to treat Peptic Ulcers and hernia.
Mr. Fu 71 years old, suffers from gastroenteropathy, ulcer and hernia.Because chronic indigestion, in 6 years, Mr. Fu feels gastrointestinal upset such as heartburn often, feel violent feeling bad when eating, have some thing morning, all will feel bad whole afternoon, he has experienced operation for several times, eats the antacid that all pharmaceutical factories produced, and does not deal with problems.But after taking olive leaf Rogor essence powdery capsule, pain has just disappeared, and takes a period of time continuously, and each one sooner or later of every day, pain occurs never again.Fact proved that olive leaf Rogor essence is the good medicine that tackles ulcer.
Embodiment 6: olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of fibromyalgia medicine or treatment and prevention fibromyalgia.
Fibromyalgia (fibromyalgia) is myalgia disease or muscle fiber pain, is often referred to the pain that occurs in fibrous tissue, muscle, tendon, ligament and other white conjunctive tissue, it is a kind of rheumatic symptom, show as severe pain, weakness, muscle and near soft tissue structure are stiff.Various symptoms may occur simultaneously, and any one meat fiber is organized all possibility pain, especially neck, shoulder, thigh etc.
Mr. Luo, 43 years old, suffer from gastropathy and prostatosis, used the symptom of a large amount of antibiotic postoperative infections not have complete obiteration, and other position of health begin pain.Neck, back chronic pain, thyroid swelling, dyspepsia comprises diarrhoea and heartburn, the most important thing is muscular tone, knot, be " fibromyalgia " on inspection.
Begin to take olive leaf Rogor essence powdery capsule, vitamin and other mineral nutritive product afterwards, took one in per 6 hours, began to increase consumption after five days, and feel good present every day 4 times, each 3, self feels good, and has not again knotted, also pain not.
His fingernail suffers from fungal infection and has reached 10 years, and the distortion that becomes has not had original color, be difficult to see, since taking olive leaf Rogor essence powdery capsule and being used for the treatment of fiber pain, fingernail is longer again, has recovered original shape and color again.
Embodiment 7: olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of respiratory tract disease or treatment and prevention respiratory tract disease.
Olive leaf Rogor essence is all very effective to the viral infection of various cold symptoms and other low level, and its effect is equivalent to the medical herbs antibiotic.In fact it can kill the sinusitis antibacterial.
Flu or influenza, some will increase intake, take the 3-4 grain in per 6 hours, and report that effect is fine.If you have met with " death " reaction, will recover original consumption, perhaps temporarily stop using, in order to obtain more physical ability, prevent disease is advised one to two of every day, increase when age of people, and intravital toxin has just needed more this replacement material when increasing.
Ganxian gives birth to, and 45 years old, because of infecting chronic sinusitis puzzlement 10 years.Take Folium olive essence powdery capsule three Zhou Banhou, it begins this long-term persistent ailment curative effect to some extent.He takes 4 every day, or per 6 hours one, take best between ante cibum or two meals.When suffering from acute influenza, per six hours 2; As health care, only need take 1-2 every day, just can reach the increase physical ability at ordinary times, prophylactic purpose.
Parotitis is a kind of children disease, but they can influence all bodies of gland and healthy.Because caused by the pathogenic bacteria direct infection as flu, parotitis is to be caused by the respiratory tract pathogenic bacteria.Parotitis patient's cough or sneeze can be far away with the several feet of germina infection.It also is the second largest reason that causes viral meningitis.
Mrs Luo, 49 years old, she experienced once serious facial infection, and she thinks that tooth obstructs at first, in fact is not to be parotitis on inspection.Before the swelling she have a fever, shake, unable, used many therapies to control these symptoms: herbtherapy, chiropractic adjustment is taken advantage of a situation and is treated or the like.Take Folium olive essence powdery capsule through suggestion, every day is eaten one in beginning, is increased to 12 afterwards.Eliminate the about Ninth Heaven of whole process of parotitis symptom, this is very short concerning an adult.Afterwards, she adheres to eating every day the invasion of 2 to 3 Folium olive essence powdery capsules with prevention respiratory tract pathogenic bacteria.It is believed that the adult suffers from parotitis and suffers from parotitis danger than the child, male especially is because pathogenic bacteria can infect male testical.The Folium olive essence is restored immunocompetence and can eliminates the various antibacterials of having an opportunity to encroach on human body, and is fine to bacterial respiratory tract disease effect, people's energy recovered, and make various functions intact.
Embodiment 8: olive leaf Rogor essence is used for the treatment of the purposes of the nutrient and healthcare products of sexually transmitted disease (STD) medicine or treatment and prevention of STD.
Infect caused disease as a kind of by simple property II type herpesvirus (HSV-11), genital herpes is trafficability characteristic contact transmission bar none almost.Generally, the patient is after being infected by contact, and the moistening fold place of skin and genitals can bear vesicle, and pain is arranged.Genital herpes is generally by the sexual transmission between the men and women, and condition of illness appeared in infected back in 4-7 days.This disease usually can be shown effect repeatedly, because virus can infect the sensory nerve maincenter of rumpbone, and hides and waits for an opportunity there to wreak havoc again, once more infected patient.And because virus is hidden in neurocyte inside, " attack cells " in the human immunity system is difficult to find them.
If the women infects this disease at phenolics, HSV-II virus can be given fetus by mother's blood-borne, or in process of production, neonate is because infected with direct contact the (when giving birth to via birth canal) of the infected organ of puerpera.The neonate that is infected can be suffered from congenital genital herpes.
For the male, it is very similar with the symptom of suffering from ulcer of penis to infect genital herpes: bear a rickle vesicle in the middle of the rubescent skin, and this symptom is more common in the front end of patient's prepuce of penis.These vesicles can heal in 5-7 days voluntarily at the wound that skin surface causes, but also may cause infecting.Wound brings pain, also is accompanied by other symptoms sometimes, as burn feeling, dysuria, fever, discomfort and the enlargement of pudendum lymph gland etc.
Female patient shows the same or analogous symptom with the male patient usually.Men and women patient feels pain when the doctor is reflected them in sexual intercourse.Genital herpes also can cause the wound of incrustation or unlimited property at women's cervix uteri, vagina and perineum place.They get off from detachment of cervix sometimes, and the vesicle at vagina place often is transformed into and is secreting mucous unlimited property wound.For all patients, this special herpes simplex virus is repeated infection outbreak regularly usually, and may be one month interval, and two months, perhaps three months.
Mrs An, 43 years old, suffer from oral area list herpes and the syphilis in 4 years, her waist is pain always also.Begin to take Folium olive essence powdery capsule through suggestion, she takes three every day, each two, only ten days, her flank pain and all herpes infection symptoms have all disappeared simultaneously, chronic problem never again, perivaginal malaise symptoms has not had yet, and the mouth wound also begins to have taken a turn for the better.Accept after this treatment, Mrs An does not present and anyly shows that she suffers from the sign or the symptom of genital herpes.Chemical compound in the olive leaf Rogor essence has stoped the generation of sexually transmitted disease (STD).In over and done with about 2 years, do not see that the symptom of any genital herpes occurs yet, as a kind of threpsology's auxiliary treatment, be free from side effects fully, and be both economical prophylactic treatment means comparatively speaking.In the disease that infection such as virus, antibacterial, fungus and candidiasis cause, use olive leaf Rogor essence and treat or auxiliary treatment, all obtained significant curative effect.In fact, this achievement that does not obtain as yet so far to generally acknowledge all shows same outstanding antibacterial effect in the application of various fields.
Embodiment 9: olive leaf Rogor essence is used for the treatment of the purposes of AIDS-treating medicine or treatment and the purposes of the nutrient and healthcare products that prevent AIDS.
Contain a kind of natural protease inhibitor in the olive leaf Rogor essence.
Mr. letter, a HIV sufferers is taken Folium olive essence powdery capsule for curing the disease, every day 4 times, eat one at every turn.Before this, the patient is once to his friend and doctor's discomfort that lymph node brought of complaining his swelling, without any agents alleviate they.(lymph node is the filter in the lymph fluid, and it prevents that other material from entering in the blood, will swelling when taking place to infect.)
After taking 5 days, the swelling phenomenon complete obiteration of patient's lymph node, laboratory test results shows that its CD sum rises to 1920 from 1380.At P
24Also be negative in the antigen test, its Western Blot test also is negative.And patient's PCR test result is not perceiveed.
After one month, its test result shows, the HIV number is still not to be perceiveed, and the Beta-2 globulin levels is still zero; P
24The antigen test is zero, and FLISH and Western BlotHIV antibody test all are negative.HIV-6 is undiscovered in blood, its CD
4Be upgraded to 114.
Mr. Qi takes 4 olive leaf Rogor essence powdery capsules every day, and approximately through after 15 week, the HZV virus amount of carrying is reduced to 19,500, CD from 37,000 in three first quarter moons
4Bring up to 296 from 239, CDs becomes 365 by 288, and leukocyte cell is raised to 2900 from 2100.
The dosage of Folium olive extract, practicality and safety:
The general use to health care dosage is therapeutic dose and treat specific dysfunction.The most general health care dosage is to take twice every day, each one 500 milligrams capsule (taking before preferably being at table); The symptom of treatment as common cold, influenza, sinusitis and the infection of ground respiration road, the dosage of recommendation are to take two 500 milligrams of capsules in per six hours; As for actute infection, as sore throat, body of gland enlargement, fever etc., the using dosage of suggestion is to take three 500 milligrams of capsules in per six hours.If what use is the olive leaf Rogor essence of high concentration, the 5ml teaspoonful approximates the capsule of a 500mg greatly.All signs (research, case study and use widely) all show olive leaf Rogor essence complementary goods seemingly as safe as a house, and it can help health to improve immunologic function and resists the caused infection of various microorganisms.
Every day is taken 4 of 500mg powdery capsules in suggestion, or per 6 hours one, take best between ante cibum or two meals.Acute influenza, per six hours 2, actute infection, more consumption effects can be better, the normal person only need take 1-2 every day, just can reach the increase physical ability, prophylactic purpose, general, old human body internal memory has a large amount of noxious substances and stronger Drug resistance.Therefore, need take more Folium olive extracting solution or its powdery capsule, if untoward reaction, consumption will reduce or temporarily stop using.
Conclusion:
1. among all kinds of patients that suffer from the disease that poison due to illness or antibacterial cause, take return to one's perfect health behind the olive leaf Rogor essence of the present invention recovery from illness and the number that sb.'s illness took a favorable turn up to 98 (98%) percent.
2. except that the patient who suffers from the weak disease of immune system, the function of immune system of other kinds sufferer also all obtains obviously to strengthen.
3. no matter be child or adult, do not find that one is taken olive leaf Rogor essence of the present invention and produces the patient of any side effect and untoward reaction.
Other clinical medicine practice finds that also the low density lipoprotein (LDL) that olive leaf Rogor essence of the present invention can reduce harmful human body cardiovascular and cerebrovascular vessel reaches more than 30 (30%) percent.
Olive leaf Rogor essence can produce on the blacklist of the serious illness of obvious curative effects to be had: acquired immune deficiency syndrome (AIDS), the depleted HIV of human immune system, leukemia, bacteremia, toxaemia, hepatitis (first type, B-mode, third type), parasitic disease, anthrax, urinary tract infection, vaginitis, pelvic inflammatory disease, botulism, encephalitis, chancroid, chickenpox, cholera, influenza, common cold, bronchitis convulsiva, diphtheria, alimentary toxicosis, gastric ulcer, gastroenteritis, serious diarrhoea, pharyngolaryngitis, tetanus, hemorrhagic fever, variola, measles, antibacterial and viral meningitis, mumps, blood-shot eye illness, thrush, pus bubble disease, poliomyelitis, rabies, rheumatic fever, typhoid, chronic fatigue syndrome, pulmonary tuberculosis, pneumonia, malaria, dengue fever, bacterial plaque, all kinds of sexually transmitted disease (STD)s of leprosy, genital herpes, herpes zoster, genital wart, gonorrhea, syphilis and oral cavity, ear, the postoperative infection of urinary system etc.
People are carrying out more deep investigation, and show that the extract in the Folium olive can suppress microbial fungi and pathogen.When staphylococcic protein secreting thing during near Olive leaf P.E, it will stop.Like this, staphylococcus becomes now and not only can control, even may eradicate, and because newfound Olive leaf P.E, we have not needed those antibiotic.
Claims (10)
1, a kind of olive leaf Rogor essence, it is characterized in that: it is to be prepared from by its weight ratio by following raw material:
Folium olive extracting solution 70-80
Cola natural juice 30-20.
2, olive leaf Rogor essence according to claim 1, it is characterized in that: it is to be prepared from by its weight ratio by following raw material:
Folium olive extracting solution 78
Cola natural juice 22.
3, olive leaf Rogor essence as claimed in claim 1 or 2 is used for the treatment of the purposes of the nutrient and healthcare products of hepatitis B medicine or treatment and prevention hepatitis B.
4, olive leaf Rogor essence as claimed in claim 1 or 2 is used to improve the purposes of the nutrient and healthcare products of function of immune system medicine or treatment and epidemic prevention systemic disease.
5, olive leaf Rogor essence as claimed in claim 1 or 2 is used for the treatment of the purposes of the nutrient and healthcare products of cardiovascular disease medicine or treatment and angiocardiopathy preventing.
6, olive leaf Rogor essence as claimed in claim 1 or 2 is used for the treatment of the purposes of the nutrient and healthcare products of Peptic Ulcers or treatment and prevention Peptic Ulcers.
7, olive leaf Rogor essence as claimed in claim 1 or 2 is used for the treatment of the purposes of the nutrient and healthcare products of fibromyalgia medicine or treatment and prevention fibromyalgia.
8, olive leaf Rogor essence as claimed in claim 1 or 2 is used for the treatment of the purposes of the nutrient and healthcare products of respiratory tract disease or treatment and prevention respiratory tract disease.
9, olive leaf Rogor essence as claimed in claim 1 or 2 is used for the treatment of the purposes of the nutrient and healthcare products of sexually transmitted disease (STD) medicine or treatment and prevention of STD.
10, olive leaf Rogor essence according to claim 9 is used for the treatment of the purposes of the nutrient and healthcare products of sexually transmitted disease (STD) medicine or treatment and prevention of STD, it is characterized in that: be used for the treatment of the purposes of AIDS-treating medicine or treatment and the purposes of the nutrient and healthcare products that prevent AIDS.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104621657A (en) * | 2014-12-26 | 2015-05-20 | 深圳市前海安测信息技术有限公司 | Health promotion-based pure natural functional drink suitable for people with hypertension to drink |
| WO2016042438A1 (en) | 2014-09-15 | 2016-03-24 | R K Technology & Investments Pte. Ltd | A novel mouth freshener composition and methods of preparation thereof |
| CN113304182A (en) * | 2020-02-26 | 2021-08-27 | 上海交通大学 | New application of olive leaf extract |
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2008
- 2008-01-07 CN CNA200810055691XA patent/CN101480428A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016042438A1 (en) | 2014-09-15 | 2016-03-24 | R K Technology & Investments Pte. Ltd | A novel mouth freshener composition and methods of preparation thereof |
| CN104621657A (en) * | 2014-12-26 | 2015-05-20 | 深圳市前海安测信息技术有限公司 | Health promotion-based pure natural functional drink suitable for people with hypertension to drink |
| CN113304182A (en) * | 2020-02-26 | 2021-08-27 | 上海交通大学 | New application of olive leaf extract |
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