CN100355392C - System for monitoring and intervening sleep and dream, and processing method therefor - Google Patents
System for monitoring and intervening sleep and dream, and processing method therefor Download PDFInfo
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- CN100355392C CN100355392C CNB2006100115710A CN200610011571A CN100355392C CN 100355392 C CN100355392 C CN 100355392C CN B2006100115710 A CNB2006100115710 A CN B2006100115710A CN 200610011571 A CN200610011571 A CN 200610011571A CN 100355392 C CN100355392 C CN 100355392C
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Abstract
The present invention provides a system for monitoring and intervening sleep and a dream and a processing method thereof, which belongs to a sleep base research field and the clinic research field of a sleep disease. The method comprises an objective physiology index for monitoring and analyzing the dream. A computer processing system judges whether a sleeper is in an REM period sleep stage according to the electrophysiological real-time record of the sleeper of a multilead sleep instrument. If the sleeper is in the REM period sleep stage, dual-stimulation test is carried out to judge the main sensory channel of dream activity. If the excitability level of a visual channel in the REM sleep stage is higher, the computer processing system can turn on a multi-color flash lamp as a means for inducing the dream. If the excitability level of an auditory channel in the REM sleep stage is higher, the computer processing system can turn on multimedia sound device to play music as a means for inducing the dream. If the excitability level of a body sensing channel in the REM sleep stage is higher, the computer processing system can control multiple resonance bed movement to change the changes of the body posture and the body position of the sleeper so as to induce out the carefree dream instead of a nightmare.
Description
Technical field
The invention belongs to sleep basic research and sleep disease clinical research field, be specifically related to monitoring and the interfering system and the processing method thereof of a kind of sleep and dream.
Background technology
Though dream interpretation is all had many sayings from ancient times to the present; But all be the subjective research category of conjesturing.Theory of Psychoanalysis is still instructing subjective inference of dream interpretation kind or the dream interpretation of conjecture property in many countries so far, lacks objective scientific method and method.The 50-60 age in 20th century, begin to utilize and lead hypnotic instrument more sleep is monitored, international polysomnogram technology can have been worked out the polysomnogram technical specification in 1967, and be topic with " sleep scoring handbook " once more in 2004, be published in his website (www.aptweb.org). lead hypnotic instrument more and mainly form by electroencephalogram, electro-oculogram and electromyogram, the electro-oculogram of record level and vertical eye movement is used to distinguish the sleep of rapid eye movement phase (REM) and nonrapid eye movements (NREM) phase (NREM) .The electrical activity that the muscle at electromyogram record lower jaw position produces is used for auxiliary REM of differentiation and NREM.According to these three kinds of electrophysiological indexs normal person's sleep at positive night is divided into 4-6 cycle, each cycle is made up of 5 Sleep stages:drowsy state (1 phase of S sleep), shallow sleeping the phase (2 phases of S sleep), in sleep the phase (3 phases of S sleep), sound sleep phase (4 phases of S sleep) and rapid eye movement phase (REM) .Because insomnia's incidence rate is higher, the reason that causes insomnia also is many-sided, and as mental sickness, physical disease, medicine and environmental factors also can cause insomnia sometimes.Therefore, lead hypnotic instrument more and be usually used in the insomnia is analyzed, so that, symptomatic treatment is carried out in insomnia according to sleep cycle and unusual Sleep stages and the disease character of generation.Utilizing when leading hypnotic instrument more, adopting again a certain stage sleep deprived the rule of observation dream sleep monitor.The experiment of this class sleep deprivation has found that REM sleep period and dream relation are closer, wakes the sleeper whenever this phase, all is reported in daydream mostly.If, just wake the sleeper up whenever entering the REM sleep, make it be not Cheng Meng, will cause depressive state; Different with it, if the NREM phase awake at the call when sleeping, then have only less than 10% person-time, be reported in daydream, what the NREM sleep deprivation caused does not have enough sleep, and mainly causes drowsiness and tired out sense rather than depressive state.The research bibliographical information of sleep and dream was slept whenever the REM phase, moved sleeper's shank, can induce and the relevant dreamland of moving; Head the sleeper sprays water smoke, can induce the dreamland of raining or falling into the water.In these scientific fact explanation sleep procedure, the stimulation that the sleeper is subjected to is relevant with dreamland; Had the people to report on magazine Brain and Cognition in 1999, the coherence analysis of EEG signals may provide index to the emotion analysis of dream.But also do not have instrumentation and method so far, be used for analyzing and intervening sleep and dream.
Summary of the invention
The purpose of this invention is to provide monitoring and the interfering system and the processing method thereof of a kind of sleep and dream, be used for monitoring and intervene the sleep dreamland, and induce carefree dream and substitute nightmare.
The monitoring and the interfering system of a kind of sleep and dream comprise:
Be provided with a multi resonant shake bed, a stereo set and a broken colour flash lamp in the environment in shielding, said apparatus can be bestowed audition, vision, body sense and stimulates lying in the shake sleeper of bed of multi resonant;
Lead hypnotic instrument: the sleeper is carried out electrophysiological real time record more;
Computer processing system: comprising: analysis module and control module, analysis module receives the sampled data lead the hypnotic instrument record and the Sleep stages of judging the sleeper more, control module according to the judged result of analysis module control respectively that multi resonant shakes bed, the opening and closing of stereo set and broken colour flash lamp.
Lead hypnotic instrument more, comprise the EEG signals sampling apparatus, the EEG signals sampling apparatus comprises the electrode and the energy transducer of physiological parameters such as electrophysiological amplifier, display and record brain wave, eye movement current potential, muscle electrical activity, respiratory wave and pulse wave, and physiological parameters such as brain wave, eye movement current potential, muscle electrical activity, respiratory wave, pulse wave are carried out electrophysiological recording.
One somatesthesia dipulse stimulator can be set on multi resonant shakes bed, be used to test the irritability of somatic sense passage.
The shake bed board of bed of multi resonant can be made up of 12 platelets of mutual flexible connection, and the arrangement mode of platelet is 3 row 4 row, and computer is controlled the activity of platelet by the shake control circuit of bed of multi resonant.
Can be provided with mattress on multi resonant shakes bed, be provided with several electronic vibrators in the mattress, computer shakes the control circuit control electronic vibrator of bed with music resonance by multi resonant.
Also can comprise a soundproof room, shake bed, stereo set and broken colour flash lamp of multi resonant is arranged in the soundproof room.
A kind of sleep and the monitoring of dream and the processing method of intervention, its step comprises:
Monitoring and the objective physical signs of dividing dream analysis, that is: lead hypnotic instrument real time record sleeper electric-physiology parameter more, computer processing system receives the sampled data of leading the hypnotic instrument record more, whether analytical judgment sleeper is in REM phase Sleep stages, in this way, computer processing system control broken colour flash lamp, stereo set or somatesthesia dipulse stimulator carry out two stimulation of vision, audition or somatesthesia to be tested, and judges in the high sensory channel of REM Sleep stages irritability level;
Bestow corresponding stimulation and induce dreamland, that is: when the visual channel when REM Sleep stages irritability level is higher, computer processing system is opened the broken colour flash lamp, as the hands section of inducing dreamland; When auditory channel when REM Sleep stages irritability level is higher, computer processing system is opened the multimedia sound equipment, plays melody or voice as the hands section of inducing dreamland; When the somatesthesia passage when REM Sleep stages irritability level is higher, the computer program control multi resonant bed motion that shakes can cause respectively that a left side or right side are stood up, head or lower limb is raised, the height variation of lathe bed etc., in order to the body gesture that changes the sleeper and the variation of position.
To bringing out current potential P50 wave analysis as the excitatoty objective physical signs of sensory channel of judging the sleeper, the ratio of the P50 ripple that brings out as two stimulations was less than 70% o'clock, and sensory channel irritability height participates in the activity of dream.
Carry out two tests that stimulate according to the order of vision, audition and somatesthesia.
Its operation principle is: the more close scientific fact of relation that the present invention is based on Sleep stages (REM phase) and dream with Rapid eye movements, at first sleep and dream are monitored, mainly be based on the electrophysiological recording and the analysis of physiological parameters such as brain wave, eye movement current potential, muscle electrical activity, respiratory wave, pulse wave, whenever the sleeper is in REM phase Sleep stages, start two stimulation tests of sensory gating immediately automatically.Participate in the activity of dream in the sensory channel of corticocerebral irritability level height (P50 ratio is less than 70%), induced dreamland with this sensory channel with brisk stimulation immediately, when for example sensory channel is audition, play brisk music.If the P50 ratio of this sensory channel, shows that it is in quiet sleep state greater than 70%, then next sensory channel is carried out two tests that stimulate.
Technique effect of the present invention and advantage: have sleeping problems common among the normal person in mind, as phenomenons such as dreaminess, nightmares, monitoring and interference sleep and dream are so that effectively induced hypnotic person's dreamland changes.
Description of drawings
Below in conjunction with accompanying drawing, the present invention is made detailed description.
Fig. 1 is sleep of the present invention and the monitoring of dream and the structural representation of interfering system;
Fig. 2 is two stimulus methods and cortex irritability level determination schematic diagram;
Fig. 3 is sleep of the present invention and the monitoring of dream and the process chart of interfering system;
Fig. 4 is the shake structural representation of bed of multi resonant in the embodiment of the invention.
The specific embodiment
With reference to figure 1, sleep and the monitoring of dream and interfering system comprise the multi resonant in soundproof room 6, the soundproof room shake bed 2, stereo set 4, broken colour flash lamp 1 and photographic head 5 and lead hypnotic instrument and computer processing system 7 more.The monitoring of sleep dream mainly is based on the electrophysiological recording of physiological parameters such as brain wave, eye movement current potential, muscle electrical activity, respiratory wave, pulse wave.The present invention adopts and leads hypnotic instrument more and write down above-mentioned electric-physiology parameter, lead hypnotic instrument more and comprise an EEG signals sampling apparatus 3, this EEG signals sub-device of sampling comprises the electrode and the energy transducer of physiological parameters such as electrophysiological amplifier, display and record brain wave, eye movement current potential, muscle electrical activity, respiratory wave and pulse wave.The sampling parameter of leading hypnotic instrument at first is set to determine the characteristic of AD sampling card and each channel amplifier more, begins then to preserve after the sampling and show that sampled data finishes until sampling.Sampled data offers computer processing system 7 and handles.
Computer processing system: comprising: analysis module and control module, analysis module receives the sampled data lead the hypnotic instrument record and the Sleep stages of judging the sleeper more, control module according to the judged result of analysis module control respectively that multi resonant shakes bed, the opening and closing of stereo set and broken colour flash lamp.With reference to figure 3, when rapid eye movement phase (REM) when occurring, computer processing system control broken colour flash lamp, stereo set or somatesthesia dipulse stimulator carry out two tests that stimulate, to spy the dreamland related content, according to the universal law of dreamland content proportion, test in proper order by vision, audition, somatesthesia.When definite dreamland is relevant with one of them content, then stop two tests that stimulate.
The irritability of two flash stimulation methods, alliteration stimulus method and sensory channels such as the test of two electric pulse skin irritation method audition, vision and somatic sense, its index is the amplitude of CEP P50 ripple.In the stimulation as shown in Figure 2, two (the black arrow that makes progress) weak point is cut interval 500ms between the stimulation (10ms), ratio and this sensory channel irritability relation of being inversely proportional between the P50 amplitude that the P50 wave amplitude that second stimulation brought out and first stimulation are brought out, percentage ratio is big more, irritability is more little, between the percentage ratio excursion 0-100%.During the REM phase slept, the brain district that irritability is high was exactly the mesencephalic centre that participates in dream, and P50 Bob value is less than 70%, (is 40% such as figure below); P50 Bob value is in quiet sleep state (is 100% such as last figure) greater than 70% brain district.Therefore, can judge the active main sensory channel of dreamland according to the excitatoty index of mesencephalic centre.
At first carry out the vision dipulse, select the monochromatic flash function of broken colour flash lamp for use, carrying out two short sound again stimulates, and selects the multimedia PA-system for use, and further can also carry out the somatesthesia dipulse stimulates, and adopts a somatesthesia dipulse stimulator.Lead the sleep dream more and analyse instrument according to event related potential (ERP) data of bringing out experiment, whether the ratio of the P50 wave amplitude that one stimulation of judgement back and last stimulation induce is greater than 70%, with the brain district (have no truck with greater than 70% dreamland, otherwise be correlated with) that determines to participate in dream.According to the excited brain district that determines, relation and the dreamland related content between each brain district, can obtain the dreamland Comprehensive analysis results.
Bestow corresponding stimulation according to two stimulation test results and induce dreamland, the stimulation of inducing of vision, audition, the relevant dreamland of somatesthesia is respectively colorful light, music and resonance bed.Computer processing system by with multi resonant shake bed, stereo set is connected with the broken colour flash lamp, controls that described multi resonant shakes bed, the opening and closing of stereo set and broken colour flash lamp.
Shake bed accessory change sleeper's posture position and two kinds of functions of pendulum sense of multi resonant wherein, as shown in Figure 4, the multi resonant bed that shakes comprises mattress on control circuit, bed board and the bed board, multi resonant shake the bed bed board form by 12 platelets of mutual flexible connection, the arrangement mode of platelet is 3 row 4 row, the shake activity of control circuit control platelet of bed of multi resonant.Control circuit is connected with computer processing system, and the computer processing system control multi resonant position change between the 3 row platelets of bed that shakes makes sleeper's Body Position Change, as from a left side or the right arm reclining of lying on the back.The computer processing system control multi resonant position changes between the 4 row platelets of bed that shake make sleeper's health the change of position take place the position up and down.Multi resonant shake the bed on can also lay mattress, a plurality of electronic vibrators 8 are housed on the mattress.Each electronic vibrator is made up of permanent magnet, bass vibrator coil, oscillating plate and radome, and it makes the sleeper produce pendulum sense (resonant frequency 20-150Hz) with the vibration of music, and its vibration with music is controlled by data wire by PC.The diameter that radome is made by the hard north material of ABS is the garden box of 44-55mm.
Whenever the visual channel when REM Sleep stages irritability level is higher, computer processing system control broken colour flash lamp is as the means of inducing dreamland.
Whenever auditory channel when REM Sleep stages irritability level is higher, computer processing system control multimedia sound equipment is play melody or voice as the means of inducing dreamland.
Whenever the somatesthesia passage when REM Sleep stages irritability level is higher, the shake motion of bed of computer processing system control multi resonant, can cause respectively that a left side or right side are stood up, head or lower limb is raised, the height variation of lathe bed etc., in order to the body gesture that changes the sleeper and the variation of position.
And the electronic vibrator that can open when playing melody or voice in the mattress produces resonance, and bestowing the pendulum sense stimulates, and induces the effect of dreamland in order to strengthen melody or voice, so that effectively induce dreamland.
Below in the mode of a concrete patient example explanation specific implementation of the present invention:
Patient Wang, 34 years old, certain city criminal policeman, poor sleep recently, bad dream continuously, dreamland many with one month before postmortem one tool is rotten relevant from the mashed corpse that is out of shape by the river, this fearful corpse jumps up suddenly and catches up with, oneself is run away desperately; But can't run, shout is waken up with a start.In the daytime absentminded often commits a fault in the work.
After patient Wang enters laboratory, the staff begin for he earlier with the electrode of good electrode cap, securement head, debugging electrode resistance.Lead after hypnotic instrument can write down the normal brain activity electrical activity, the staff withdraws from screened room more, please he is quiet sleeping.Lead the hypnotic instrument opening entry after about 15 minutes, the staff constantly observes spontaneous brain electricity ripple signal more, can see the brain electrical acti of 1 phase of sleep after about 20 minutes, spend 40 minutes again, the brainwave activity that 4 phases (sound sleep) occur the eye movement activity occurred after 15 minutes, illustrated to enter the REM sleep period.Computer processing system begins to carry out two tests that stimulate, utilize the broken colour flash lamp to grant the two flash stimulations of patient earlier, test result is that visual area is in excitatory state, computer processing system starts alternating flashing light immediately and opens the multi resonant bed that shakes, cause that lower limb is raised and the variation repeatedly that reduces down, counted 10 minutes, and found that the sleeper is in the REM sleep period always.Wake the sleeper subsequently up and ask its dreamland.As if he says just and has a dream that the someone chases after oneself, see the sky wild goose of flying here, and oneself one kicks one's legs and rides up on the wild goose, has flown, and the people who chases after me lags far behind .....Three REM phases of this night, all carried out same procedure, wherein two the stimulation tested, and also comprised alliteration stimulus method and two electric pulse skin irritation, found that each dreamland is all with the action of running fast, jump, flying.The dream of the very night does not occur being chased after to such an extent that run the nightmare do not take off again.For the patient is no longer had nightmares, also adopted in the REM phase and to have looked, listen to have stimulated provocative test, the melody of broken colour flick of lamp and 5.1 sound channels: " white clouds in the sky waft and waft ... ", wake the patient at broadcast melody and broken colour flash stimulation after 10 minutes, it claims: dream about a beautiful garden, a beautiful big butterfly appears, oneself jump up and butterfly flies simultaneously, feel again to be sitting on the big aircraft or the like a little while, after this Wang's sleep normally nightmare do not occur again in the week.
Claims (6)
1, the monitoring and the interfering system of a kind of sleep and dream comprise:
Be provided with a multi resonant shake bed, a stereo set and a broken colour flash lamp in the environment in shielding, said apparatus is bestowed audition, vision, body sense and is stimulated lying in the shake sleeper of bed of multi resonant;
Lead hypnotic instrument: the sleeper is carried out electrophysiological real time record more;
Computer processing system: comprise analysis module and control module, analysis module receives the sampled data lead the hypnotic instrument record and the Sleep stages of judging the sleeper more, control module according to the judged result of analysis module control respectively that multi resonant shakes bed, the opening and closing of stereo set and broken colour flash lamp.
2, the monitoring of sleep as claimed in claim 1 and dream and interfering system, it is characterized in that: lead hypnotic instrument more, comprise an EEG signals sampling apparatus, the EEG signals sampling apparatus comprises the electrode and the energy transducer of electrophysiological amplifier, display and record physiological parameter, physiological parameter to the sleeper is carried out electrophysiological recording, and described physiological parameter comprises brain wave, eye movement current potential, muscle electrical activity, respiratory wave and pulse wave.
3, the monitoring of sleep as claimed in claim 1 or 2 and dream and interfering system is characterized in that: a somatesthesia dipulse stimulator is set on multi resonant shakes bed, is used to test the irritability of somatic sense passage.
4, the monitoring of sleep as claimed in claim 1 and dream and interfering system, it is characterized in that: multi resonant shake the bed bed board form by 12 platelets of mutual flexible connection, the arrangement mode of platelet is 3 row 4 row, and the multi resonant bed that shakes is provided with control circuit, is used to control the activity of platelet.
5, as the monitoring and the interfering system of claim 1 or 4 described sleeps and dream, it is characterized in that: on multi resonant shakes bed, be provided with mattress, be provided with several electronic vibrators in the mattress.
6, the monitoring of sleep as claimed in claim 1 and dream and interfering system is characterized in that: also comprise a soundproof room, shake bed, stereo set and broken colour flash lamp of multi resonant is arranged in the soundproof room.
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