CA2077528A1 - Device to collect and facilitate analysis of saliva - Google Patents
Device to collect and facilitate analysis of salivaInfo
- Publication number
- CA2077528A1 CA2077528A1 CA 2077528 CA2077528A CA2077528A1 CA 2077528 A1 CA2077528 A1 CA 2077528A1 CA 2077528 CA2077528 CA 2077528 CA 2077528 A CA2077528 A CA 2077528A CA 2077528 A1 CA2077528 A1 CA 2077528A1
- Authority
- CA
- Canada
- Prior art keywords
- arrangement
- differing
- aim
- saliva
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/0003—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements including means for analysis by an unskilled person
Abstract
ABSTRACT
An arrangement for the collection of human saliva, differing in that with the aim to diminish the time of collection of saliva with a simultaneous increase in accuracy of the sample volume and its subsequent analysis, the arrangement is made of transparent material, the bottom being a malleable transparent bag, the top part of which is affixed to a rigid cylindrical form, the lid ends in a hollow tube, and on the side part of the rigid cylinder there is a rigid, hollow branch pipe, which is connected to a manual pump.
An arrangement for the collection of human saliva, differing in that with the aim to diminish the time of collection of saliva with a simultaneous increase in accuracy of the sample volume and its subsequent analysis, the arrangement is made of transparent material, the bottom being a malleable transparent bag, the top part of which is affixed to a rigid cylindrical form, the lid ends in a hollow tube, and on the side part of the rigid cylinder there is a rigid, hollow branch pipe, which is connected to a manual pump.
Description
2~7~528 DEVIOE ~ co~r AND FACILIT~I~ ~;I~,YSIS OF '~ALIVA
An alTangement for the collection and simultaneous analysis of saliva ~or the detection of the presence of and the concentration of alcohol in the human body.
This invention relates to those apparatus, which allow for both the collection and the simultaneous analysis of saliva for the detection of the presence of and concentration of alcohol in the human body; And more particularly this invention is directed to diminish the time in ~vhich saliva samples are collected, and to increase the accuracy in the selection of sample volume, and thereby to increase accuracy in detection of the presence oÇ and the concen~ration of alcohol in the human body.
At the present time, many arrangements are known for the collection of human saliva.
However, they can all be divided into either of two categories. The flrst category is the arrangements ~or collection by pipettes (see example: sample pipette "arid E;:eagent Pipette" of the firm DuPont de Demours Int. U.S.A. Geneva) and their analogues.
Such arrangements allow the collection of only very small samples of saliva, moreover, the suction of the saliva can only be done once, since during the collection of the next portion O
saliva, any foam resulting from the first suction will remain in the pipette and this will impede further collection. These concerns, preclude the simultaneous analysis of the saliva by the methocl of mixing the saliva with any reagent.
':
~- , . , :, . ., . . : .
; ; : ~ : . , : . , ~ . .: ., .
~ ~7~
The second category of arrangements is for collection by e~cpectoration or absorption. In the first case, because of the low viscosity of the saliva, its collcction is very difficult and it often demands up to S - 10 minutes for the collection of even a small sample. Additionally, because saliva is most often found in a foam state, the foam may talce up the greatest volume of the sample, thereby rendering it impossible to determine what volume of saliva is actually collected, with consequent negative effects upon the reliability of subsequent analysis and this leads to a sharp decrease in the reliability of the results.
When absorbents are used for the collection of saliva, the problems of ~oam and sample volume disappear, but another important problem occurs. It is difficult to extract the saliva rrom the absorbent without causing any disorders in the saliva's chemical composition. Firstly, it is necessary to do the extracting under laboratory conditions with the help of a centrifuge. Secondly, the possibility is not excluded, that the target or substance to be detected can be left in part on the absorbent. Therefore this category of arrangements is not suitable for the express - collection of saliva and its simultaneous analysis for the presence of and the concentrations of alcohol .
The aim of the present invention is an arrangement, which diminishes the time for the collection of the saliva sample coupled with a simultaneous increase in the accuracy of determining the sample volume, the cumulative effect of which allows for the introduction of methods and reagents for the express analysis of the sarnple all within the same arrangement. This includes the express detection of the presence of and of the concentration of alcohol in human saliva.
The components of the arrangement are made variously from rigid and semi-rigid, transparent materials, such as poly-eurothane or poly-s~rene. The bottom of the arrangement is in the shape of a rectangular serni-rigid sack. The top part of the sack is affixed to a rigid cylindrical forni. The exterior of the cylinder is threaded, by means of which, is affixed a rigid inverted cone narrowing to a rigid hollow tube. The side of the rigid cylinder is connected to a manual pump (sylphone with an elastic capacity for interchanging volume of air for the creation of rarefactions .. . . - -: . :
::
: : ' :
':
2 ~ 2 ~
necessary for the s~lc~ion of saliva into the arrangement). The arrangement is additionally provi(led ~vith a detachable detective elemen~, which is a short cylinder open at both ends and capable of fitting immediately within the rigid cylinder. 'rhe top of the short cylinder is flanged so as to engage the rirn of the rigid cylinder. The bottom of the short cylinder ha~s a scseen mounted to its interior walls. Asides from this, the arrangement is provided with a glass ampule present in the semi-rigid sack. The ampule is protected from any accidental destruction by a plastic ring. The arrangement is also provided with an opaque, light - proof (impenetrable) capacity for the storage of the detective elements of the arrangement . The arrangement also is equipped with a form of felt pen. The tip of the felt is a cylinder cut orthogonal to its height. In the bottom part of the semi-rigid sack on its exterior surface, a colored line is drawn, which serves as an indicator of the quantity of the liquid portion of the saliva sample.
The reagents are organi~ed as follows, a (liquid) reagent is at all times present in the semi-rigid sack, a second (liquid) reagent is present in the glass ampule, a third (dry) reagent is imprinted in filter paper which is to be affixed to the screen of the detective element, a fourth (liquid) reagent is present in the reservoir of the felt pen.
Drawings of the arrangement illustrating the embodiments of the invention are presented where:
Figure 1 is a cross-sectional view of the arrangement;
Figure 2 is a cross-sectional view of the arrangernent with the cone lid removed and the detective element (Figure 4.) inserted for use.
Figure 3 is a cross-sectional view of the detective element (Figure 4) in its light impenetrable storage container.
Figure 4 is a cross-sectional view of the detec~ive element Figure 5 is a top plan view of the detective element Figure 6 is a cross-sectional view of the felt, inclusive of its tip (21), cap and reservoir (20).
Figure 7 is a cross-sectional view of the apparatus after use Figures 8 through 21 are views of the apparatus of this invention to illustrate steps in the use of the apparatus.
, . .
. - . , - .
,', ~ '~' , - ' ' ' ' ~' 2~3~2~
In Figure 1 the following embodiments are apparent:
1. Iid on hollow tube;
2. hollow tube and inverted cone;
An alTangement for the collection and simultaneous analysis of saliva ~or the detection of the presence of and the concentration of alcohol in the human body.
This invention relates to those apparatus, which allow for both the collection and the simultaneous analysis of saliva for the detection of the presence of and concentration of alcohol in the human body; And more particularly this invention is directed to diminish the time in ~vhich saliva samples are collected, and to increase the accuracy in the selection of sample volume, and thereby to increase accuracy in detection of the presence oÇ and the concen~ration of alcohol in the human body.
At the present time, many arrangements are known for the collection of human saliva.
However, they can all be divided into either of two categories. The flrst category is the arrangements ~or collection by pipettes (see example: sample pipette "arid E;:eagent Pipette" of the firm DuPont de Demours Int. U.S.A. Geneva) and their analogues.
Such arrangements allow the collection of only very small samples of saliva, moreover, the suction of the saliva can only be done once, since during the collection of the next portion O
saliva, any foam resulting from the first suction will remain in the pipette and this will impede further collection. These concerns, preclude the simultaneous analysis of the saliva by the methocl of mixing the saliva with any reagent.
':
~- , . , :, . ., . . : .
; ; : ~ : . , : . , ~ . .: ., .
~ ~7~
The second category of arrangements is for collection by e~cpectoration or absorption. In the first case, because of the low viscosity of the saliva, its collcction is very difficult and it often demands up to S - 10 minutes for the collection of even a small sample. Additionally, because saliva is most often found in a foam state, the foam may talce up the greatest volume of the sample, thereby rendering it impossible to determine what volume of saliva is actually collected, with consequent negative effects upon the reliability of subsequent analysis and this leads to a sharp decrease in the reliability of the results.
When absorbents are used for the collection of saliva, the problems of ~oam and sample volume disappear, but another important problem occurs. It is difficult to extract the saliva rrom the absorbent without causing any disorders in the saliva's chemical composition. Firstly, it is necessary to do the extracting under laboratory conditions with the help of a centrifuge. Secondly, the possibility is not excluded, that the target or substance to be detected can be left in part on the absorbent. Therefore this category of arrangements is not suitable for the express - collection of saliva and its simultaneous analysis for the presence of and the concentrations of alcohol .
The aim of the present invention is an arrangement, which diminishes the time for the collection of the saliva sample coupled with a simultaneous increase in the accuracy of determining the sample volume, the cumulative effect of which allows for the introduction of methods and reagents for the express analysis of the sarnple all within the same arrangement. This includes the express detection of the presence of and of the concentration of alcohol in human saliva.
The components of the arrangement are made variously from rigid and semi-rigid, transparent materials, such as poly-eurothane or poly-s~rene. The bottom of the arrangement is in the shape of a rectangular serni-rigid sack. The top part of the sack is affixed to a rigid cylindrical forni. The exterior of the cylinder is threaded, by means of which, is affixed a rigid inverted cone narrowing to a rigid hollow tube. The side of the rigid cylinder is connected to a manual pump (sylphone with an elastic capacity for interchanging volume of air for the creation of rarefactions .. . . - -: . :
::
: : ' :
':
2 ~ 2 ~
necessary for the s~lc~ion of saliva into the arrangement). The arrangement is additionally provi(led ~vith a detachable detective elemen~, which is a short cylinder open at both ends and capable of fitting immediately within the rigid cylinder. 'rhe top of the short cylinder is flanged so as to engage the rirn of the rigid cylinder. The bottom of the short cylinder ha~s a scseen mounted to its interior walls. Asides from this, the arrangement is provided with a glass ampule present in the semi-rigid sack. The ampule is protected from any accidental destruction by a plastic ring. The arrangement is also provided with an opaque, light - proof (impenetrable) capacity for the storage of the detective elements of the arrangement . The arrangement also is equipped with a form of felt pen. The tip of the felt is a cylinder cut orthogonal to its height. In the bottom part of the semi-rigid sack on its exterior surface, a colored line is drawn, which serves as an indicator of the quantity of the liquid portion of the saliva sample.
The reagents are organi~ed as follows, a (liquid) reagent is at all times present in the semi-rigid sack, a second (liquid) reagent is present in the glass ampule, a third (dry) reagent is imprinted in filter paper which is to be affixed to the screen of the detective element, a fourth (liquid) reagent is present in the reservoir of the felt pen.
Drawings of the arrangement illustrating the embodiments of the invention are presented where:
Figure 1 is a cross-sectional view of the arrangement;
Figure 2 is a cross-sectional view of the arrangernent with the cone lid removed and the detective element (Figure 4.) inserted for use.
Figure 3 is a cross-sectional view of the detective element (Figure 4) in its light impenetrable storage container.
Figure 4 is a cross-sectional view of the detec~ive element Figure 5 is a top plan view of the detective element Figure 6 is a cross-sectional view of the felt, inclusive of its tip (21), cap and reservoir (20).
Figure 7 is a cross-sectional view of the apparatus after use Figures 8 through 21 are views of the apparatus of this invention to illustrate steps in the use of the apparatus.
, . .
. - . , - .
,', ~ '~' , - ' ' ' ' ~' 2~3~2~
In Figure 1 the following embodiments are apparent:
1. Iid on hollow tube;
2. hollow tube and inverted cone;
3. threaded lid of the rigid cylinder;
4. rigid cylinder;
5. hollow branch;
6. purnp (sylphone~;
8. semi-rigid transparent bag;
9. plastic safety device on arnpule;
10. glass ampule with the reagent;
11. dry reagent; . .
12. sample size indicator line;
13. valve;
In Figure 2. the arrangement is shown with the cone lid removed and the detective element (Figure 4) inserted for use. Visible here are, 14. flange of detachable detective element;
15. detective element (filter) impregnated with dry reagent;
16. circular fixator (ring) of ~e detective element;
In Figure 3. one is given a cross-sectional view of the detective element (Figure 4) in its light : ~
impenetrable storage container where, ::
18. Iight impenetrable capacity ~or the storage of the detective elements;
.
In Figure 4. one is given a cross-sectional view of the detective element and in Figure 5 one is provided with an overview of the same detective element in which are visible, 17.. screen supportive platforrn of the detective elerment (15);
19. zone of the detective element (15) in which final reagent is added;
In Figure 6. one is given a cross~sectionai view of the felt, inclusive of its tip (21), cap and reservoir (20).
20. Iiquid reagent;
:
2 ~
21. the tip part of the felt is finished at an angle of 90 degrees, to provide aconsistent and balanced application of the the reagent to the detective element (15) In Figure 7. one is given a cross-sectional view of the apparatus following its use, recapped and ready for disposal.
The arrangement is used in the following manner. The target individual takes the lid (1) and previously squeezed sylphone (6), places a hollow branch pipe (2~ in the mouth, so that the tip of the branch pipe ~2) is dipped into his saliva. Afterwards, he releases the sylphone (6) and because of the created rarefaction, saliva is sucked into the arrangement. This process is repeated, that of squeezing of the sylphone (6) and suction of the saliva, until such time as the saliva sample is observed to match the indicator (12) level marked on the side of the semi-rigid bag.
The size of sample can be conveniently checked by tipping the package to an appropriate angle. After the needed quantity of the saliva has been collected the lid (3) is removed and in its place is put the detective element (15), so that its nange (14) fits firrnly on the cylinder (4). The tip of the felt (21) which is at an angle of 90 de~rees, is touched to the surface of the detective element (15), in the zone (19). The ampule is then crushed by finger pressure upon the safety ring on the ampule (9). The apparatus is then carefully agitated, ensuring that the detective element (15) is not moistened. The resulting chemical reaction releases vapors, which will in turn react with the - detective element in zone (19). A change in color intensity will be observed which after 30-40 seconds will stabilize. This color may be compared with a standard scale, which provides an accurato reading of ethanol concentrations.
It is a unique characteristic of this apparatus that it allows one to distinguish which of the alcohols is contained in the body, ethylic or meth~ylic. This can be particularly important in the carc of poisoning. Moreover, the entire cycle of analysis, starting with collecting and ending ~vith ` .` ' ' : '` " '` : ~' ` ' , ` ,: ` `
::: ' ' ' ':` ' : . ' detection of the presence of alcohol requires between 3 - 5 minutes, and the detection itself demands only 30 ~ 40 seconds.
A ~urther unique characteristic of this apparatus is that the dctective element is detachable and in the case of urgency, one can conduct not only a subjective or visual diagnosis, but also an an objective one, by placing the detective element (15) in a special instrument (ie. in a type of glucometer). It is important to make a note, that the detective element (15) situated between the circular fixator (16) and hollow platfonn (17) is provicled with an access to the vapors, which arc developed in the process of the reaction and at the same time that it is stabilized and prevented by the elements of the arrangement (16 - 17) from deforrnation.
After use one may again screw on the lid (3), which hermetically covers the arrangement and prevents the components of the reaction from entering into the surrounding environrnent.
Figures 8 through 21 illustrate the first eight steps ~n the use of the apparatus o~ this invention. The remaining steps in the use of the apparatus are as follaws:
, . : ~.
:: ' ,:~ :
. . . . . .
:- ~ : , ' - .,; ,
8. semi-rigid transparent bag;
9. plastic safety device on arnpule;
10. glass ampule with the reagent;
11. dry reagent; . .
12. sample size indicator line;
13. valve;
In Figure 2. the arrangement is shown with the cone lid removed and the detective element (Figure 4) inserted for use. Visible here are, 14. flange of detachable detective element;
15. detective element (filter) impregnated with dry reagent;
16. circular fixator (ring) of ~e detective element;
In Figure 3. one is given a cross-sectional view of the detective element (Figure 4) in its light : ~
impenetrable storage container where, ::
18. Iight impenetrable capacity ~or the storage of the detective elements;
.
In Figure 4. one is given a cross-sectional view of the detective element and in Figure 5 one is provided with an overview of the same detective element in which are visible, 17.. screen supportive platforrn of the detective elerment (15);
19. zone of the detective element (15) in which final reagent is added;
In Figure 6. one is given a cross~sectionai view of the felt, inclusive of its tip (21), cap and reservoir (20).
20. Iiquid reagent;
:
2 ~
21. the tip part of the felt is finished at an angle of 90 degrees, to provide aconsistent and balanced application of the the reagent to the detective element (15) In Figure 7. one is given a cross-sectional view of the apparatus following its use, recapped and ready for disposal.
The arrangement is used in the following manner. The target individual takes the lid (1) and previously squeezed sylphone (6), places a hollow branch pipe (2~ in the mouth, so that the tip of the branch pipe ~2) is dipped into his saliva. Afterwards, he releases the sylphone (6) and because of the created rarefaction, saliva is sucked into the arrangement. This process is repeated, that of squeezing of the sylphone (6) and suction of the saliva, until such time as the saliva sample is observed to match the indicator (12) level marked on the side of the semi-rigid bag.
The size of sample can be conveniently checked by tipping the package to an appropriate angle. After the needed quantity of the saliva has been collected the lid (3) is removed and in its place is put the detective element (15), so that its nange (14) fits firrnly on the cylinder (4). The tip of the felt (21) which is at an angle of 90 de~rees, is touched to the surface of the detective element (15), in the zone (19). The ampule is then crushed by finger pressure upon the safety ring on the ampule (9). The apparatus is then carefully agitated, ensuring that the detective element (15) is not moistened. The resulting chemical reaction releases vapors, which will in turn react with the - detective element in zone (19). A change in color intensity will be observed which after 30-40 seconds will stabilize. This color may be compared with a standard scale, which provides an accurato reading of ethanol concentrations.
It is a unique characteristic of this apparatus that it allows one to distinguish which of the alcohols is contained in the body, ethylic or meth~ylic. This can be particularly important in the carc of poisoning. Moreover, the entire cycle of analysis, starting with collecting and ending ~vith ` .` ' ' : '` " '` : ~' ` ' , ` ,: ` `
::: ' ' ' ':` ' : . ' detection of the presence of alcohol requires between 3 - 5 minutes, and the detection itself demands only 30 ~ 40 seconds.
A ~urther unique characteristic of this apparatus is that the dctective element is detachable and in the case of urgency, one can conduct not only a subjective or visual diagnosis, but also an an objective one, by placing the detective element (15) in a special instrument (ie. in a type of glucometer). It is important to make a note, that the detective element (15) situated between the circular fixator (16) and hollow platfonn (17) is provicled with an access to the vapors, which arc developed in the process of the reaction and at the same time that it is stabilized and prevented by the elements of the arrangement (16 - 17) from deforrnation.
After use one may again screw on the lid (3), which hermetically covers the arrangement and prevents the components of the reaction from entering into the surrounding environrnent.
Figures 8 through 21 illustrate the first eight steps ~n the use of the apparatus o~ this invention. The remaining steps in the use of the apparatus are as follaws:
, . : ~.
:: ' ,:~ :
. . . . . .
:- ~ : , ' - .,; ,
Claims (11)
1. An arrangement for the collection of human saliva, differing in that with the aim to diminish the time of collection of saliva with a simultaneous increase in accuracy of the sample volume and its subsequent analysis, the arrangement is made of transparent material, the bottom being a malleable transparent bag, the top part of which is affixed to a rigid cylindrical form, the lid ends in a hollow tube, and on the side part of the rigid cylinder there is a rigid, hollow branch pipe, which is connected to a manual pump.
2. An arrangement as in point 1, differing in that, with the aim to increase the accuracy of the sample size of the saliva collected, a corner of the bottom portion of the malleable bag is marked with a line.
3. An arrangement as in point 1., differing in that, for the collection of and simultaneous multi-stage multiple reagent analysis of human saliva, the lid of the rigid cylinder is threaded so as to allow for its removal after the collection of saliva and prior to its analysis.
4. An arrangement as in point 3., differing in that with the aim to facilitate the introduction of a liquid reagent during analysis, the arrangement is provided with a crushable glass ampule with said reagent loaded inside, all within the malleable bag.
5. An arrangement as in point 4., differing in that with the aim to prevent accidental self -destruction of the glass ampule, it is provided with an elastic protective ring.
6. An arrangement as in point 3., differing in that, with the aim to facilitate the introduction of further dry reagents during analysis, the arrangement is provided with a detachable detective element in the form of a hollow cylinder the radius of which is such as to only just allow the hollow cylinder to pass within the rigid cylinder, on the top part of of the hollow cylinder is a flange, of a circumference sufficient to engage the upper edge of the rigid cylinder, and in the bottom of the hollow cylinder a screen is affixed to the interior walls.
On the screen a detective element may be mounted (for example filter paper with the dry reagent), and fixed on the supportive platform with the circular holder (latch).
On the screen a detective element may be mounted (for example filter paper with the dry reagent), and fixed on the supportive platform with the circular holder (latch).
7. An arrangement as in point 6., differing in that, with the aim to prevent the decrease in the concentration of vapors on the detective element, the arrangement is provide with a valve closing the side branch pipe on which the manual pump is fixed.
8. An arrangement as in point 7., differing in that, with the aim to facilitate the introduction of photo-sensitive reagents during analysis, the detective elements containing these reagents are provided with a light proof container in which they are kept until the moment of their use.
9. An arrangement as in points 3. through 7., differing in that, with the aim to facilitate the introduction of a second liquid reagent during analysis, a felt pen, the reservoir of which is filled with the second liquid reagent is provided, the tip of which felt may be used to apply the said reagent to the detective element.
10. An arrangement as in point 9., differing in that, with the aim to increase the accuracy of the application of the second liquid reagent to the detective element, the tip of the felt is cut orthogonal to its length.
11. An arrangement as in points 3. through 10., differing in that, for the express detection of the presence of and an express determination of the concentrations of ethanol in the human body, a dry reagent is present in the malleable bag, a liquid reagent is present in the glass ampule within the malleable bag, a second liquid reagent is present in the reservoir of the felt pen, and a final photosensitive dry reagent is impregnated on a filter paper affixed to the detective element and sealed in its opaque container.
9. THE PROCESS MAY BE COMPLEMENTED BY USE OF EQUIPMENT, WHICH
READ THE DETECTIVE ELEMENT DIRECTLY AND PROVIDE A WRITTEN
RECORD OF ETHANOL CONCENTRATIONS
10. ONCE COMPLETED THE FILTER PORTION OF THE DETECTIVE ELEMENT MAY
BE REMOVED AND ATTACHED TO THE RECORD
11. AFTER USE, THE ENTIRE APPARATUS MAY BE RESEALED WITH ITS THE LID, THEREBY RENDERING IT SAFE FOR DISPOSAL
9. THE PROCESS MAY BE COMPLEMENTED BY USE OF EQUIPMENT, WHICH
READ THE DETECTIVE ELEMENT DIRECTLY AND PROVIDE A WRITTEN
RECORD OF ETHANOL CONCENTRATIONS
10. ONCE COMPLETED THE FILTER PORTION OF THE DETECTIVE ELEMENT MAY
BE REMOVED AND ATTACHED TO THE RECORD
11. AFTER USE, THE ENTIRE APPARATUS MAY BE RESEALED WITH ITS THE LID, THEREBY RENDERING IT SAFE FOR DISPOSAL
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2077528 CA2077528A1 (en) | 1992-09-03 | 1992-09-03 | Device to collect and facilitate analysis of saliva |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2077528 CA2077528A1 (en) | 1992-09-03 | 1992-09-03 | Device to collect and facilitate analysis of saliva |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2077528A1 true CA2077528A1 (en) | 1994-03-04 |
Family
ID=4150371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2077528 Abandoned CA2077528A1 (en) | 1992-09-03 | 1992-09-03 | Device to collect and facilitate analysis of saliva |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2077528A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999022645A1 (en) * | 1997-10-31 | 1999-05-14 | Primed Halberstadt Medizintechnik Gmbh | Device for collecting and releasing saliva |
| US6022326A (en) * | 1998-10-30 | 2000-02-08 | Lifepoint, Inc. | Device and method for automatic collection of whole saliva |
| FR2784023A1 (en) * | 1998-10-02 | 2000-04-07 | Michel Gleizes | Analysis container for medical sample has transparent plastics pot with holes in stopper for sample extraction and suction tubes |
| CN112754535A (en) * | 2021-01-20 | 2021-05-07 | 东北农业大学 | Pig saliva collection system |
-
1992
- 1992-09-03 CA CA 2077528 patent/CA2077528A1/en not_active Abandoned
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999022645A1 (en) * | 1997-10-31 | 1999-05-14 | Primed Halberstadt Medizintechnik Gmbh | Device for collecting and releasing saliva |
| US6416715B1 (en) | 1997-10-31 | 2002-07-09 | It Dr. Gambert Gmbh | Device for collecting and releasing saliva |
| FR2784023A1 (en) * | 1998-10-02 | 2000-04-07 | Michel Gleizes | Analysis container for medical sample has transparent plastics pot with holes in stopper for sample extraction and suction tubes |
| US6022326A (en) * | 1998-10-30 | 2000-02-08 | Lifepoint, Inc. | Device and method for automatic collection of whole saliva |
| CN112754535A (en) * | 2021-01-20 | 2021-05-07 | 东北农业大学 | Pig saliva collection system |
| CN112754535B (en) * | 2021-01-20 | 2022-06-03 | 东北农业大学 | Pig saliva collection system |
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