DE9315698U1
(en)
*
|
1993-10-14 |
1993-12-23 |
Buechi Lab Tech |
Evaporator flask for a rotary evaporator
|
AU2002250143A1
(en)
*
|
2001-03-16 |
2002-10-03 |
Eli Lilly And Company |
Lp mammalian proteins; related reagents
|
KR100576674B1
(en)
|
2001-06-20 |
2006-05-10 |
제넨테크, 인크. |
Compositions and Methods for the Diagnosis and Treatment of Tumor
|
US20030068691A1
(en)
*
|
2001-07-16 |
2003-04-10 |
Applera Corporation |
Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof
|
ATE553193T1
(en)
*
|
2001-08-30 |
2012-04-15 |
Arca Biopharma Inc |
METHODS AND MATERIALS RELATED TO STEM CELL GROWTH FACTOR-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES
|
MXPA04003057A
(en)
*
|
2001-10-04 |
2005-06-20 |
Immunex Corp |
Ul16 binding protein 4.
|
US7202056B2
(en)
|
2002-03-28 |
2007-04-10 |
Bristol-Myers Squibb Company |
Polynucleotides encoding a human cell surface protein with immunoglobulin folds, BGS-19
|
WO2003091436A1
(en)
*
|
2002-04-26 |
2003-11-06 |
Fujisawa Pharmaceutical Co., Ltd. |
Novel 35 kd protein
|
US20050276812A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
WO2004005335A2
(en)
*
|
2002-07-05 |
2004-01-15 |
Borean Pharma A/S |
Multimerised growth hormone fusion proteins
|
DE60335552D1
(en)
|
2002-09-11 |
2011-02-10 |
Genentech Inc |
NEW COMPOSITION AND METHOD FOR THE TREATMENT OF IMMUNE DISEASES
|
CN1703524B
(en)
|
2002-09-30 |
2010-04-07 |
肿瘤疗法科学股份有限公司 |
Genes and polypeptides relating to human pancreatic cancer
|
PL378582A1
(en)
|
2003-03-19 |
2006-05-02 |
Biogen Idec Ma Inc. |
Nogo receptor binding protein
|
AU2004276646B2
(en)
|
2003-09-29 |
2012-07-12 |
Chugai Seiyaku Kabushiki Kaisha |
Protein expressed in NK cell
|
EP1679372B1
(en)
*
|
2003-10-30 |
2009-02-18 |
Kazusa DNA Research Institute Foundation |
Novel plexin polypeptide, dna encoding the same and use thereof
|
SG195524A1
(en)
|
2003-11-06 |
2013-12-30 |
Seattle Genetics Inc |
Monomethylvaline compounds capable of conjugation to ligands
|
RU2343158C2
(en)
*
|
2004-01-27 |
2009-01-10 |
Ньювело, Инк. |
Gastrointestinal proliferative factor and its applications
|
GB0403491D0
(en)
*
|
2004-02-17 |
2004-03-24 |
Univ Cambridge Tech |
Polypeptides, methods and means
|
US20050186577A1
(en)
|
2004-02-20 |
2005-08-25 |
Yixin Wang |
Breast cancer prognostics
|
US7901881B2
(en)
|
2004-04-09 |
2011-03-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Diagnostic tool for diagnosing benign versus malignant thyroid lesions
|
AU2005258335B2
(en)
|
2004-06-24 |
2011-03-17 |
Biogen Ma Inc. |
Treatment of conditions involving demyelination
|
EP1771578A2
(en)
*
|
2004-07-23 |
2007-04-11 |
EVOTEC Neurosciences GmbH |
Diagnostic and therapeutic use of slim3 for neurodegenerative diseases
|
AU2005286607B2
(en)
|
2004-09-23 |
2011-01-27 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
EP3683230A1
(en)
|
2005-05-12 |
2020-07-22 |
ZymoGenetics, Inc. |
Compositions and methods for modulating immune responses
|
MX2008000253A
(en)
|
2005-07-08 |
2008-04-02 |
Biogen Idec Inc |
Sp35 antibodies and uses thereof.
|
US8044179B2
(en)
|
2005-09-13 |
2011-10-25 |
National Research Council Of Canada |
Methods and compositions for modulating tumor cell activity
|
GB0522113D0
(en)
*
|
2005-10-28 |
2005-12-07 |
Ares Trading Sa |
vWFA-domain containing proteins
|
GB0525999D0
(en)
*
|
2005-12-21 |
2006-02-01 |
Ares Trading Sa |
Novel members of the kazal family of serine protease inhibitors
|
GB0615287D0
(en)
*
|
2006-08-01 |
2006-09-06 |
Ares Trading Sa |
Integral membrane protein
|
CA2665223A1
(en)
*
|
2006-10-02 |
2008-05-29 |
The Scripps Research Institute |
An enzyme regulating ether lipid signaling pathways
|
GB0620735D0
(en)
*
|
2006-10-18 |
2006-11-29 |
Ares Trading Sa |
Proteins
|
ES2553169T5
(en)
|
2007-07-02 |
2023-11-30 |
Oncomed Pharm Inc |
Compositions and methods for the treatment and diagnosis of cancer
|
GB0805159D0
(en)
|
2008-03-19 |
2008-04-23 |
Sancho Madrid David |
Immune modulation via C-type lectin
|
AU2008294074B2
(en)
*
|
2007-08-30 |
2015-01-22 |
Walter And Eliza Hall Institute Of Medical Research |
Dendritic cell marker and uses thereof
|
CA2697992C
(en)
*
|
2007-10-04 |
2017-08-22 |
Zymogenetics, Inc. |
B7 family member zb7h6 and related compositions and methods
|
EP2217697B1
(en)
*
|
2007-11-08 |
2015-06-10 |
Biogen MA Inc. |
Use of lingo-4 antagonists in the treatment of conditions involving demyelination
|
KR101855381B1
(en)
|
2008-04-09 |
2018-05-09 |
제넨테크, 인크. |
Novel compositions and methods for the treatment of immune related diseases
|
JP2011519959A
(en)
*
|
2008-05-13 |
2011-07-14 |
ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ |
Methods for detecting cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells
|
EP2315779A2
(en)
|
2008-07-09 |
2011-05-04 |
Biogen Idec MA Inc. |
Compositions comprising antibodies to lingo or fragments thereof
|
US8227417B2
(en)
|
2008-07-25 |
2012-07-24 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
HMGN polypeptides as immune enhancers and HMGN antagonists as immune suppressants
|
EP3441458B9
(en)
|
2009-02-03 |
2023-08-23 |
Koninklijke Nederlandse Akademie van Wetenschappen |
Culture medium for epithelial stem cells and organoids comprising said stem cells
|
US9752124B2
(en)
|
2009-02-03 |
2017-09-05 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Culture medium for epithelial stem cells and organoids comprising the stem cells
|
EP2412800A1
(en)
|
2010-07-29 |
2012-02-01 |
Koninklijke Nederlandse Akademie van Wetenschappen |
Liver organoid, uses thereof and culture method for obtaining them
|
KR101962476B1
(en)
|
2009-07-03 |
2019-03-26 |
아비펩 피티와이 리미티트 |
Immuno-conjugates and methods for producing them
|
WO2011004404A1
(en)
*
|
2009-07-10 |
2011-01-13 |
Decode Genetics Ehf |
Genetic variants for predicting risk of glaucoma
|
US8470980B2
(en)
|
2009-09-09 |
2013-06-25 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
AU2010324506B2
(en)
|
2009-11-24 |
2015-02-26 |
Alethia Biotherapeutics Inc. |
Anti-clusterin antibodies and antigen binding fragments and their use to reduce tumor volume
|
EP2516462B1
(en)
|
2009-12-23 |
2015-05-06 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
DK2528625T3
(en)
|
2010-04-15 |
2013-10-14 |
Spirogen Sarl |
Pyrrolobenzodiazepines and their conjugates
|
CN114246952A
(en)
|
2010-06-08 |
2022-03-29 |
基因泰克公司 |
Cysteine engineered antibodies and conjugates
|
CN105061534A
(en)
|
2010-09-22 |
2015-11-18 |
艾丽奥斯生物制药有限公司 |
Substituted nucleotide analogs
|
US20120121615A1
(en)
|
2010-11-17 |
2012-05-17 |
Flygare John A |
Alaninyl maytansinol antibody conjugates
|
EP3103810A3
(en)
|
2011-04-21 |
2017-03-08 |
Garvan Institute of Medical Research |
Modified variable domain molecules and methods for producing and using them
|
ES2567276T3
(en)
|
2011-05-12 |
2016-04-21 |
Genentech, Inc. |
LC-MS / MS method of monitoring multiple reactions to detect therapeutic antibodies in animal samples using frame-changing peptides
|
RU2014101669A
(en)
|
2011-07-15 |
2015-09-20 |
Онкомед Фармасьютикалс, Инк. |
AGENTS BINDING R-SPONDIN PROTEINS (RSPO), AND WAYS OF THEIR APPLICATION
|
CN103987407B
(en)
|
2011-10-14 |
2016-08-24 |
麦迪穆有限责任公司 |
Pyrrolobenzodiazepines Zhuo and conjugate thereof
|
US8980865B2
(en)
|
2011-12-22 |
2015-03-17 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
US9822170B2
(en)
|
2012-02-22 |
2017-11-21 |
Alethia Biotherapeutics Inc. |
Co-use of a clusterin inhibitor with an EGFR inhibitor to treat cancer
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
US8916538B2
(en)
|
2012-03-21 |
2014-12-23 |
Vertex Pharmaceuticals Incorporated |
Solid forms of a thiophosphoramidate nucleotide prodrug
|
EP2827876A4
(en)
|
2012-03-22 |
2015-10-28 |
Alios Biopharma Inc |
Pharmaceutical combinations comprising a thionucleotide analog
|
CN104470541A
(en)
|
2012-05-14 |
2015-03-25 |
比奥根艾迪克Ma公司 |
Lingo-2 antagonists for treatment of conditions involving motor neurons
|
NZ704269A
(en)
|
2012-07-13 |
2016-05-27 |
Oncomed Pharm Inc |
Rspo3 binding agents and uses thereof
|
CA2885340C
(en)
|
2012-10-12 |
2016-11-08 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
ES2660029T3
(en)
|
2012-10-12 |
2018-03-20 |
Medimmune Limited |
Antibody-pyrrolobenzodiazepine conjugates
|
JP6392763B2
(en)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugate
|
MX364327B
(en)
|
2012-10-12 |
2019-04-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates.
|
RS57694B1
(en)
|
2012-10-12 |
2018-11-30 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine - anti-psma antibody conjugates
|
HUE039329T2
(en)
|
2012-10-12 |
2018-12-28 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
ES2680153T3
(en)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Anti-PSMA-pyrrolobenzodiazepine antibody conjugates
|
WO2014096365A1
(en)
|
2012-12-21 |
2014-06-26 |
Spirogen Sàrl |
Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
|
ES2658888T5
(en)
|
2012-12-21 |
2021-10-19 |
Medimmune Ltd |
Pyrrolobenzodiazepines and their conjugates
|
NZ710745A
(en)
|
2013-03-13 |
2019-03-29 |
Genentech Inc |
Pyrrolobenzodiazepines and conjugates thereof
|
JP6340019B2
(en)
|
2013-03-13 |
2018-06-06 |
メドイミューン・リミテッドMedImmune Limited |
Pyrrolobenzodiazepine and its conjugates
|
AU2014230735B2
(en)
|
2013-03-13 |
2018-03-15 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3021869B1
(en)
|
2013-07-16 |
2020-07-15 |
F. Hoffmann-La Roche AG |
Methods of treating cancer using pd-1 axis binding antagonists and tigit inhibitors
|
EA201690195A1
(en)
|
2013-08-12 |
2016-05-31 |
Дженентек, Инк. |
ANTIBODY CONJUGATE CONNECTIONS ON THE BASIS OF DIMER 1- (HLORMETHYL) -2,3-DIGYDRO-1H-BENZO [E] INDOL AND METHODS OF APPLICATION AND TREATMENT
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
WO2015052532A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
US9950078B2
(en)
|
2013-10-11 |
2018-04-24 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
PE20161394A1
(en)
|
2013-12-16 |
2017-01-06 |
Genentech Inc |
PEPTIDOMIMETIC COMPOUNDS AND THEIR ANTIBODY-DRUG CONJUGATES
|
JP6980384B2
(en)
|
2013-12-16 |
2021-12-15 |
ジェネンテック, インコーポレイテッド |
1- (Chloromethyl) -2,3-dihydro-1H-benzo [E] indole dimer antibody-drug conjugate compound, and methods of use and treatment
|
MX371092B
(en)
|
2013-12-16 |
2020-01-16 |
Genentech Inc |
Peptidomimetic compounds and antibody-drug conjugates thereof.
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3191134B1
(en)
|
2014-09-12 |
2019-11-20 |
Genentech, Inc. |
Anthracycline disulfide intermediates, antibody-drug conjugates and methods
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
BR112017003236A2
(en)
|
2014-09-12 |
2017-11-28 |
Genentech Inc |
cysteine engineered antibodies, drug conjugates and antibodies, drug and antibody conjugate preparation method and pharmaceutical composition
|
US10064937B2
(en)
|
2014-09-16 |
2018-09-04 |
Oncomed Pharmaceuticals, Inc. |
Treatment of dermal fibrosis
|
CR20170099A
(en)
|
2014-09-17 |
2017-07-19 |
Genentech Inc |
PIRROLOBENZODIAZEPINAS AND CONJUGADOS DE ANTIBERPOS-DISULFURO DE LAS SISAS
|
MX2017006770A
(en)
|
2014-11-25 |
2018-02-09 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates.
|
EP3226909A1
(en)
|
2014-12-03 |
2017-10-11 |
Genentech, Inc. |
Quaternary amine compounds and antibody-drug conjugates thereof
|
JP2018504400A
(en)
|
2015-01-08 |
2018-02-15 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
LINGO-1 antagonist and use for treatment of demyelinating disorders
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
AU2016325610B2
(en)
|
2015-09-25 |
2019-10-10 |
Genentech, Inc. |
Anti-TIGIT antibodies and methods of use
|
MA43345A
(en)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
PYRROLOBENZODIAZEPINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
MA43354A
(en)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
CONJUGATE DRUG CONJUGATES WITH CLOUDY DISULPHIDE
|
MA45326A
(en)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
CALICHEAMICIN-ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
US20170315132A1
(en)
|
2016-03-25 |
2017-11-02 |
Genentech, Inc. |
Multiplexed total antibody and antibody-conjugated drug quantification assay
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
JP2019522633A
(en)
|
2016-05-20 |
2019-08-15 |
ジェネンテック, インコーポレイテッド |
PROTAC antibody conjugates and methods of use
|
CN109313200B
(en)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
Bioanalytical methods for characterizing site-specific antibody-drug conjugates
|
WO2017214024A1
(en)
|
2016-06-06 |
2017-12-14 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
WO2018031662A1
(en)
|
2016-08-11 |
2018-02-15 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
WO2018065501A1
(en)
|
2016-10-05 |
2018-04-12 |
F. Hoffmann-La Roche Ag |
Methods for preparing antibody drug conjugates
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
US10961305B2
(en)
|
2016-12-21 |
2021-03-30 |
Mereo Biopharma 3 Limited |
Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta
|
PT3544636T
(en)
|
2017-02-08 |
2021-05-04 |
Medimmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
WO2018192944A1
(en)
|
2017-04-18 |
2018-10-25 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
KR20190141666A
(en)
|
2017-04-20 |
2019-12-24 |
에이디씨 테라퓨틱스 에스에이 |
Combination Therapy with Anti-AXL Antibody-Drug Conjugates
|
AU2018285562B2
(en)
|
2017-06-14 |
2024-01-18 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-CD19 ADC
|
ES2906965T3
(en)
|
2017-08-18 |
2022-04-21 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
WO2019060398A1
(en)
|
2017-09-20 |
2019-03-28 |
Ph Pharma Co., Ltd. |
Thailanstatin analogs
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
CN112638944A
(en)
|
2018-08-23 |
2021-04-09 |
西进公司 |
anti-TIGIT antibody
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
TW202037381A
(en)
|
2018-10-24 |
2020-10-16 |
瑞士商赫孚孟拉羅股份公司 |
Conjugated chemical inducers of degradation and methods of use
|
WO2020123275A1
(en)
|
2018-12-10 |
2020-06-18 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
GB202211117D0
(en)
*
|
2022-07-29 |
2022-09-14 |
Replay Holdings Llc |
Compositions and methods for non-immunogenecity
|