AU2002220031A1 - Methods of using cd8+/tcr- facilitating cells (fc) for the engraftment of purified hematopoietic stem cells (hsc) - Google Patents
Methods of using cd8+/tcr- facilitating cells (fc) for the engraftment of purified hematopoietic stem cells (hsc)Info
- Publication number
- AU2002220031A1 AU2002220031A1 AU2002220031A AU2003102A AU2002220031A1 AU 2002220031 A1 AU2002220031 A1 AU 2002220031A1 AU 2002220031 A AU2002220031 A AU 2002220031A AU 2003102 A AU2003102 A AU 2003102A AU 2002220031 A1 AU2002220031 A1 AU 2002220031A1
- Authority
- AU
- Australia
- Prior art keywords
- cells
- hsc
- engraftment
- tcr
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 210000004027 cell Anatomy 0.000 title 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24889500P | 2000-11-14 | 2000-11-14 | |
US60/248,895 | 2000-11-14 | ||
PCT/US2001/045312 WO2002040640A2 (en) | 2000-11-14 | 2001-11-14 | Methods of using cd8+/tcr- facilitating cells (fc) for the engraftment of purified hematopoietic stem cells (hsc) |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002220031A1 true AU2002220031A1 (en) | 2002-05-27 |
Family
ID=22941146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002220031A Abandoned AU2002220031A1 (en) | 2000-11-14 | 2001-11-14 | Methods of using cd8+/tcr- facilitating cells (fc) for the engraftment of purified hematopoietic stem cells (hsc) |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002220031A1 (en) |
WO (1) | WO2002040640A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10131971A1 (en) * | 2001-07-02 | 2003-01-30 | Cytonet Gmbh & Co Kg | Preparation of hematopoietic stem cell preparations, useful in transplants for treating leukemia and viral infections, does not induce graft versus host disease |
AU2002322857A1 (en) * | 2001-08-01 | 2003-02-17 | Jewish Hospital Healthcare Services, Inc. | Cellular compositions which facilitate engraftment of hematopoietic stem cells while minimizing the risk of gvhd |
US11291686B2 (en) | 2008-05-30 | 2022-04-05 | University Of Louisville Research Foundation, Inc. | Human facilitating cells |
US8632768B2 (en) * | 2008-05-30 | 2014-01-21 | University Of Louisville Research Foundation, Inc. | Human facilitating cells |
CN104470542A (en) | 2011-12-22 | 2015-03-25 | 耶达研究及发展有限公司 | A combination therapy for a stable and long term engraftment |
US20150110738A1 (en) * | 2012-05-04 | 2015-04-23 | University Of Southern California | Methods and compositions for generating and using allogeneic suppressor cells |
CN105188755A (en) | 2013-02-26 | 2015-12-23 | 小利兰·斯坦福大学托管委员会 | Combined organ and hematopoietic cells for transplantation tolerance of grafts |
WO2019178106A1 (en) | 2018-03-12 | 2019-09-19 | Medeor Therapeutics, Inc. | Methods for treating non-cancerous disorders using hematopoietic cells |
US10842821B2 (en) | 2018-04-05 | 2020-11-24 | Medeor Therapeutics, Inc. | Cellular compositions derived from prior organ donors and methods of manufacture and use thereof |
US10881692B2 (en) | 2018-04-05 | 2021-01-05 | Medeor Therapeutics, Inc. | Compositions for establishing mixed chimerism and methods of manufacture thereof |
US11813376B2 (en) | 2018-09-18 | 2023-11-14 | Medeor Therapeutics, Inc. | Cellular compositions derived from deceased donors to promote graft tolerance and manufacture and uses thereof |
US11435350B2 (en) | 2018-09-18 | 2022-09-06 | Medeor Therapeutics, Inc. | Methods of analysis of blood from deceased donors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5772994A (en) * | 1993-05-28 | 1998-06-30 | The University Of Pittsburgh | Hematopoietic facilitatory cells and their uses |
-
2001
- 2001-11-14 AU AU2002220031A patent/AU2002220031A1/en not_active Abandoned
- 2001-11-14 WO PCT/US2001/045312 patent/WO2002040640A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2002040640A2 (en) | 2002-05-23 |
WO2002040640A3 (en) | 2002-09-12 |
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