AU2002216254A1 - Drive mechanism for an injection device - Google Patents

Drive mechanism for an injection device

Info

Publication number
AU2002216254A1
AU2002216254A1 AU2002216254A AU2002216254A AU2002216254A1 AU 2002216254 A1 AU2002216254 A1 AU 2002216254A1 AU 2002216254 A AU2002216254 A AU 2002216254A AU 2002216254 A AU2002216254 A AU 2002216254A AU 2002216254 A1 AU2002216254 A1 AU 2002216254A1
Authority
AU
Australia
Prior art keywords
shuttle
housing
drive mechanism
movement
cartridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002216254A
Other versions
AU2002216254B2 (en
Inventor
Shane Alistair Day
Christopher Nigel Langley
Robert Frederick Veasey
Robert Woolston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DCA Design International Ltd
Original Assignee
DCA Design International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0031466.6A external-priority patent/GB0031466D0/en
Application filed by DCA Design International Ltd filed Critical DCA Design International Ltd
Publication of AU2002216254A1 publication Critical patent/AU2002216254A1/en
Application granted granted Critical
Publication of AU2002216254B2 publication Critical patent/AU2002216254B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Description

DRIVE MECHANISM FOR AN INJECTION DEVICE
The present invention relates to improvements in an injection device, and in particular to improvements in a portable injection device for dispensing controlled quantities of a medicament.
Typically such injection devices are used by those suffering from diabetes to administer a dose of insulin or insulin-type medicine to themselves. It will be understood that such injection devices are suitable for the injection of other medicines.
At one time, such doses were administered by use of a disposable syringe; the syringe first being filled from a separate phial or other container and then used to inject the dose. However, there were a number of difficulties in such an arrangement. In particular, such an arrangement was not suitable for the infirm. For others, the social stigma associated with such syringes made their public use problematic.
To overcome these difficulties a number of so-called pen-type injectors have been developed. These devices are small, being capable of being carried in a jacket pocket or the like and allow a number of doses to be obtained from a cartridge or ampoule contained within the injector. The present invention has particular application to such pen-type injectors.
While such pen-type injectors are a considerable improvement upon disposable hypodermic syringes, problems nevertheless remain.
In particular when considering the design of a drive system for a pen-type injector, there are a number of, sometimes, conflicting technical requirements. The drive system must be accurate and reliable, and at the same time compact and efficient. The drive system must be reliable and robust; being able to function for the life of the product. The drive system must also be intrinsically fail-safe. It is an advantage of the present invention that it eliminates, or at least substantially reduces such problems. The present invention also provides for improved ease of use and improved interaction with a user.
The invention will now be described, by way of example only, with reference to the accompanying drawings; in wl ich:-
Figure 1 shows a plan view of a pen-type injector in accordance with the present invention; Figure 2 shows a similar view to Figure 1 with an end cap of the injector omitted; Figure 3 shows a cross-sectional view of the injector of Figures 1 and 2; and Figure 4 shows in plan view a part of a drive mechanism for use with an injector in accordance with the present invention.
Referring first to Figures 1 to 3, there can be seen a pen-type injector 2 in accordance with the present invention. The injector 2 comprises a main housing 4 to which is releasably secured an end cap or cover 6.
At a first end of the main housing 4 there is provided a control panel region 8. This region includes a display panel 10, typically a LCD display, and a first dose button 12 and a second dose button 14, the first and second dose buttons being operated to increase or decrease a dose of medicament to be delivered. The control panel region 10 in the illustrated embodiment also includes an arm button 16.
At the first end of the main housing there is also provided a dispense button 18. Preferably, when not depressed, the dispense button- 18 is flush with the main housing 4.
Along a longitudinal axis of the injector 2, to each side of the control panel region 10 are provided a number of grooves or recesses 20. These aid in the gripping of the injector 2 by a user. At a second end of the main housing 4 a needle unit 22 is releasably secured to the main housing. The second end of the main housing 4 is also provided with a shaped portion 24.
In use a cartridge 40 or ampoule of medicament is stored in the housing 4 behind the shaped portion 24. For preference, the shaped portion is transparent to permit the cartridge 40 to be seen by a user.
A primer button 26 is also provided on the second end of the housing 4. It will be
> understood that when the end cap 6 is in place over the second end of the housing, it will not be possible inadvertently to depress the primer button 26 or to be pricked by the needle unit 22. A cover detection switch 28 may also be included at the second end of the main housing 4 to detect whether the end cap or cover 6 is in place or not.
In Figure 3, there can be seen a priming contact 30, an arm contact 32, a first dose contact 34 and a second dose contact 36 corresponding to the respective buttons. A dispense contact 19 corresponding to the dispense button 18 is also shown.
With reference to Figure 3 it may be seen that there is provided a suitable location for a power source 38 such as a battery or batteries. There is also a suitable region in which a cartridge 40 or ampoule of medicament is to be located. This region may be accessed by way of the removable shaped portion 24 of the main housing 4 to allow for replacement of the cartridge 40 or ampoule as required by the user.
In a third region of the main housing 4 there is provided a drive mechanism 42 which operates from the power source 38 and acts upon the cartridge 40 or ampoule of medicament. The cartridge 40 or ampoule comprises a container 44 or sleeve closed at one end by a cover 46 at a head end thereof, and sealed at the other by a movable bung 48 or stopper. When in position, the needle unit 22 pierces the cover 46 and movement of the bung 48 towards the cover 46 will cause the medicament contained within the cartridge 40 or ampoule to be expelled. The cartridge may be a 3ml cartridge in accordance with ISO/FDIS 11608 Part 3, or any other suitable cartridge to suit the injector.
Movement of the bung 48 or stopper is caused by movement of a piston or plunger 50 forming a part of the drive mechanism 42. The piston or plunger 50 is movable between a first fully withdrawn position (not shown) which allows for the replacement of the cartridge 40 or ampoule and a second fully extended portion in which as much medicament as possible has been expelled from the cartridge 40 or ampoule. An end stop switch 52 may be provided in the main housing 4 to detect when the piston 50 is in the fully withdrawn position. Tripping of the switch end stop 52 may release a catch or other fastening device to allow access to the main housing 4 for replacement of the cartridge 40.
The drive mechanism 42 is operated by a motor 54 under the control of an electronic control unit (not shown). The motor 54 should be reversible in order to allow the piston 50 to be moved between the first and second positions. In Figure 3, the motor 54 can be seen to drive the piston 50 by way of a gear train 42, such that rotation of a third rotor 58 causes the piston 50 to be moved in relation to the third rotor 58.
Preferably, the user can feel the vibration of the motor 54 and the associated drive mechanism 42 and/or hear them in operation. In this way an added degree of confidence in the fact of the operation of the injector 2 is provided to the user.
In order to harness a solenoid for use in an injector, a mechanism has been developed to convert the reciprocating motion of a solenoid into an incremental linear motion to displace a cartridge bung. Referring to Figure 4, a two piece shuttle 300 is constrained rotationally within a housing 302 for free axial movement therein. A double faced gear component 304 is also located within the housing. The double faced gear component 304 is free for movement rotationally, but constrained axially. The double faced gear component 304 is coupled to a shaft 306 of a lead screw. The lead screw will be understood to comprise piston means for the advancement of bung 48 within a medicament cartridge 40 within the context of this description. The shuttle comprises two ferrite cores 308,310, each with teeth on an inner face thereof. At either end the housing 302 are disposed coils 312,314. An annular permanent magnet 316 is used to latch the mechanism in one of two end positions when the cores and their associated coils are not energised.
In the de-energised condition, the shuttle 300 is held latched to one end of the device by the magnet 316. The shuttle is held in position by a closed magnetic 'circuit' passing through one of the shuttle ferrite cores and a casing of the housing 302.
In order to move the shuttle 300 to the opposite end of the housing both coils 312,314 are energised. The coil at the 'latched' end is energised to oppose the magnetic field of the permanent magnet 316; the coil at the opposite end is energised to reinforce the permanent magnetic field. The shuttle 300 is thus pulled from the rest position to the opposite end of the housing 302. In moving from one end of the housing 302 to the other, the shuttle 300 engages with the double faced gear component 304 causing it to rotate by a fixed increment, thereby turning a shaft 320 of a lead screw.
When the shuttle 300 comes to rest at the opposite end of the housing 302, it is again latched in position by the permanent magnet 316.
The mechanism can be seen to work on both strokes of the solenoid. Also, it can be latched at either end allowing for finer control of the lead screw.

Claims (1)

1 A drive mechanism for an injection device in which piston means 306 are selectively driven to expel medicament from within a medicament cartridge 40 and a drive mechanism for controlling the movement of the piston means, the drive mechanism comprising a housing 302, a shuttle 300 located for movement within the housing 302 along a longitudinal axis between a first position and a second position, drive means to move the shuttle 300 within the housing 302, a gear component 304 located within the housing 302 for rotation about the longitudinal axis and associated with the piston means 306, movement of the shuttle 300 between each of the first and the second positions causing movement of the piston means 306.
2 A drive mechanism according to claim 1, characterised in that the drive means comprises separately energisable coils 312,314 located at each end of the housing 302 and an annular permanent magnet 316 located between the coils 312,314 acting upon the shuttle 300, the shuttle 300 comprising at least one ferrite core 308,310.
3 A drive mechanism according to claim 1 or claim 2, characterised in that the shuttle 300 and the gear component 304 are each provided with teeth upon an annular surface thereof, engagement of the shuttle 300 with the gear component 304 causing the gear component 304 to be rotated by a fixed increment.
AU2002216254A 2000-12-22 2001-12-21 Drive mechanism for an injection device Ceased AU2002216254B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0031466.6A GB0031466D0 (en) 2000-12-22 2000-12-22 Improvements in and relating to an injection device
GB0031466.6 2000-12-22
PCT/GB2001/005741 WO2002051474A1 (en) 2000-12-22 2001-12-21 Drive mechanism for an injection device

Publications (2)

Publication Number Publication Date
AU2002216254A1 true AU2002216254A1 (en) 2003-01-23
AU2002216254B2 AU2002216254B2 (en) 2007-01-25

Family

ID=9905751

Family Applications (12)

Application Number Title Priority Date Filing Date
AU2002216231A Ceased AU2002216231B2 (en) 2000-12-22 2001-12-21 Drive mechanism for an injection device
AU2002216256A Ceased AU2002216256B2 (en) 2000-12-22 2001-12-21 Injection device with replaceable cartridge
AU2002216230A Ceased AU2002216230B2 (en) 2000-12-22 2001-12-21 Drive mechanism for an injection device
AU2002216235A Ceased AU2002216235B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002222302A Ceased AU2002222302B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002217283A Ceased AU2002217283B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002216236A Ceased AU2002216236B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002216232A Ceased AU2002216232B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002216254A Ceased AU2002216254B2 (en) 2000-12-22 2001-12-21 Drive mechanism for an injection device
AU2002217288A Ceased AU2002217288B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2007201951A Ceased AU2007201951B2 (en) 2000-12-22 2007-04-26 Pen-type injector having holding mechanism for medicament cartridge
AU2007202032A Ceased AU2007202032B2 (en) 2000-12-22 2007-05-01 Dosing means for an injection device.

Family Applications Before (8)

Application Number Title Priority Date Filing Date
AU2002216231A Ceased AU2002216231B2 (en) 2000-12-22 2001-12-21 Drive mechanism for an injection device
AU2002216256A Ceased AU2002216256B2 (en) 2000-12-22 2001-12-21 Injection device with replaceable cartridge
AU2002216230A Ceased AU2002216230B2 (en) 2000-12-22 2001-12-21 Drive mechanism for an injection device
AU2002216235A Ceased AU2002216235B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002222302A Ceased AU2002222302B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002217283A Ceased AU2002217283B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002216236A Ceased AU2002216236B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2002216232A Ceased AU2002216232B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2002217288A Ceased AU2002217288B2 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit
AU2007201951A Ceased AU2007201951B2 (en) 2000-12-22 2007-04-26 Pen-type injector having holding mechanism for medicament cartridge
AU2007202032A Ceased AU2007202032B2 (en) 2000-12-22 2007-05-01 Dosing means for an injection device.

Country Status (19)

Country Link
US (13) US20040054328A1 (en)
EP (13) EP1349587B1 (en)
JP (16) JP4287145B2 (en)
KR (13) KR100826218B1 (en)
CN (13) CN100400117C (en)
AT (12) ATE294600T1 (en)
AU (12) AU2002216231B2 (en)
BR (13) BR0116296B1 (en)
CA (13) CA2430914C (en)
CY (3) CY1106128T1 (en)
DE (12) DE60127303T3 (en)
DK (12) DK1349587T3 (en)
ES (12) ES2240340T3 (en)
GB (1) GB0031466D0 (en)
HK (12) HK1059586A1 (en)
IL (22) IL156245A0 (en)
MX (13) MXPA03005593A (en)
PT (12) PT1349591E (en)
WO (13) WO2002051477A1 (en)

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