ATE289219T1 - METHOD FOR PRODUCING A PARTIALLY PERMEABLE HOLLOW FIBER MEMBRANE FROM POLYSULFONE - Google Patents

METHOD FOR PRODUCING A PARTIALLY PERMEABLE HOLLOW FIBER MEMBRANE FROM POLYSULFONE

Info

Publication number
ATE289219T1
ATE289219T1 AT96304796T AT96304796T ATE289219T1 AT E289219 T1 ATE289219 T1 AT E289219T1 AT 96304796 T AT96304796 T AT 96304796T AT 96304796 T AT96304796 T AT 96304796T AT E289219 T1 ATE289219 T1 AT E289219T1
Authority
AT
Austria
Prior art keywords
polysulfone
hollow fiber
membranes
albumin permeability
producing
Prior art date
Application number
AT96304796T
Other languages
German (de)
Inventor
Masaaki Shimagaki
Fumiaki Fukui
Takeshi Sonoda
Koji Sugita
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Application granted granted Critical
Publication of ATE289219T1 publication Critical patent/ATE289219T1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/66—Polymers having sulfur in the main chain, with or without nitrogen, oxygen or carbon only
    • B01D71/68—Polysulfones; Polyethersulfones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • B01D69/087—Details relating to the spinning process
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/022—Encapsulating hollow fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/0233—Manufacturing thereof forming the bundle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/02—Membrane cleaning or sterilisation ; Membrane regeneration
    • B01D65/022—Membrane sterilisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
    • B01D67/0011—Casting solutions therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
    • B01D67/0016—Coagulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/009—After-treatment of organic or inorganic membranes with wave-energy, particle-radiation or plasma
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A61M2202/0421—Beta-2-microglobulin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/16—Flow or flux control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/14—Specific spacers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/34—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling by radiation
    • B01D2321/346—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling by radiation by gamma radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/06—Specific viscosities of materials involved
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/08—Specific temperatures applied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/08—Specific temperatures applied
    • B01D2323/081—Heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/15—Use of additives
    • B01D2323/218—Additive materials
    • B01D2323/2182—Organic additives
    • B01D2323/21839—Polymeric additives
    • B01D2323/2187—Polyvinylpyrolidone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/219—Specific solvent system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/30—Cross-linking
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/50—Control of the membrane preparation process
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B01D2325/0283—Pore size
    • B01D2325/02832—1-10 nm
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/20—Specific permeability or cut-off range
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/36—Hydrophilic membranes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2973—Particular cross section
    • Y10T428/2975—Tubular or cellular

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Artificial Filaments (AREA)

Abstract

Respective hollow fiber membranes suitable for use in removing undesired contaminants from blood, in particular in an artificial kidney, have: (1) per membrane area of 1.6 m<2>, in vitro clearances for urea and phosphorus respectively of ≥ 195, and ≥ 180, ml/min, a beta 2-microglobulin clearance ≥ 44 ml/min and an albumin permeability ≤ 0.5%; (2) an albumin permeability ≤ 1.5% and an overall mass transfer coefficient Ko ≥ 0.0012 cm/min; and (3) a vitamin B12 dialyzance of ≥ 135 ml/min and an albumin permeability ≤ 3%. The membranes can be prepared by spinning hollow fibers from a spinning solution comprising a polysulfone, a hydrophilic polymer, a solvent and water, the spinning solution having a viscosity x at 30 DEG C of 25-130 poise and a quantity y % of water given by: <MATH> The membranes can be incorporated into a hemodialyzer module by a method in which they are preimpregnated with a wetting agent, thereafter kept separate from one another by spacers and then inserted in the module.
AT96304796T 1995-06-30 1996-06-28 METHOD FOR PRODUCING A PARTIALLY PERMEABLE HOLLOW FIBER MEMBRANE FROM POLYSULFONE ATE289219T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP16646395 1995-06-30
JP16499195 1995-06-30
JP16646295 1995-06-30

Publications (1)

Publication Number Publication Date
ATE289219T1 true ATE289219T1 (en) 2005-03-15

Family

ID=27322418

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96304796T ATE289219T1 (en) 1995-06-30 1996-06-28 METHOD FOR PRODUCING A PARTIALLY PERMEABLE HOLLOW FIBER MEMBRANE FROM POLYSULFONE

Country Status (9)

Country Link
US (2) US5938929A (en)
EP (1) EP0750938B1 (en)
KR (2) KR100432463B1 (en)
CN (1) CN1125669C (en)
AT (1) ATE289219T1 (en)
CA (1) CA2180222C (en)
DE (1) DE69634352T2 (en)
ES (1) ES2237760T3 (en)
TW (1) TW474835B (en)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355730B1 (en) * 1995-06-30 2002-03-12 Toray Industries, Inc. Permselective membranes and methods for their production
KR100351886B1 (en) * 1997-05-19 2002-09-12 아사히 메디칼 가부시키가이샤 Polysulfone-Base Hollow-Fiber Hemocathartic Membrane And Processes For The Production Thereof
US7144505B2 (en) * 1997-09-18 2006-12-05 Baxter International Inc. Melt-spun polysulfone semipermeable membranes and methods for making the same
US6218441B1 (en) 1997-09-18 2001-04-17 Timothy B. Meluch Melt-spun polysulfone semipermeable membranes and methods for making the same
JP4211168B2 (en) * 1999-12-21 2009-01-21 東レ株式会社 Dialyzer manufacturing method and sterilization method
CN1263534C (en) * 2001-07-24 2006-07-12 旭化成医疗株式会社 Hollow fiber membrane for purifying blood and method for preparation thereof
SG99371A1 (en) * 2001-08-17 2003-10-27 Environmental Technology Inst Hollow fiber membrane for the treatment of waste lubricants and method for its production
US6766259B2 (en) * 2002-07-29 2004-07-20 Baxter International Inc. System and a method for detecting fiber damage in a dialyzer
KR101135840B1 (en) * 2002-08-21 2012-04-16 도레이 카부시키가이샤 Modified substrate, separation membrane and separation membrane system
CA2498244C (en) * 2002-09-12 2012-03-06 Teruhiko Oishi Plasma purification membrane and plasma purification system
SE0203855L (en) * 2002-12-20 2004-06-21 Gambro Lundia Ab Perm-selective membrane
SE0203857L (en) * 2002-12-20 2004-06-21 Gambro Lundia Ab Perm-selective membrane and process for its manufacture
US20040140259A1 (en) * 2003-01-20 2004-07-22 Cummings James A. Membrane flux enhancement
JPWO2005028500A1 (en) * 2003-09-05 2008-03-06 東レ株式会社 Method for preparing a solution having a different composition of biological components
TWI406703B (en) * 2003-11-17 2013-09-01 Asahi Kasei Medical Co Ltd Purify blood with hollow fiber membrane and use its blood purifier
JP3580314B1 (en) * 2003-12-09 2004-10-20 東洋紡績株式会社 Polysulfone-based selectively permeable hollow fiber membrane bundle and method for producing the same
DE102004008220B4 (en) 2004-02-19 2006-01-12 Membrana Gmbh High-flux dialysis membrane with improved separation behavior
DE102004008221B4 (en) * 2004-02-19 2006-01-26 Membrana Gmbh Dialysis membrane with improved agent molecule removal
JP3642065B1 (en) 2004-03-22 2005-04-27 東洋紡績株式会社 Permselective separation membrane and method for producing a selectively permeable separation membrane
JP3636199B1 (en) * 2004-03-23 2005-04-06 東洋紡績株式会社 Polysulfone-based permselective hollow fiber membrane bundle, method for producing the same and blood purifier
US7226432B2 (en) * 2004-05-03 2007-06-05 Clear View Patient Safety Products, Llc Blood drawing device
WO2006024902A1 (en) * 2004-08-06 2006-03-09 Asahi Kasei Medical Co., Ltd. Polysulfone hemodialyzer
US20080000830A1 (en) * 2004-08-10 2008-01-03 Kimihiro Mabuchi Highly Water Permeable Hollow Fiber Membrane Type Blood Purifier and Process for Manufacturing the Same
JP3772909B1 (en) * 2005-04-04 2006-05-10 東洋紡績株式会社 Blood purifier
KR100646312B1 (en) * 2005-06-10 2006-11-23 (주)에어레인 Hollow fiber membrane for oxygen separation and preparation method thereof
EP1875957B1 (en) * 2006-07-07 2010-03-03 Gambro Lundia AB Plasma separation membrane
ES2342966T3 (en) * 2006-07-07 2010-07-20 Gambro Lundia Ab PLASMA SEPARATION MEMBRANE.
US20080135481A1 (en) * 2006-12-06 2008-06-12 General Electric Company Polyarylethernitrile hollow fiber membranes
US20110168631A1 (en) * 2006-12-15 2011-07-14 General Electric Company Methods and apparatuses for water filtration using polyarylether membranes
US7695628B2 (en) * 2006-12-15 2010-04-13 General Electric Company Polyarylether membranes
US7977451B2 (en) * 2006-12-15 2011-07-12 General Electric Company Polyarylether membranes
CA2727673A1 (en) 2008-06-10 2009-12-17 Aquatech International Corporation Preparation of high performance ultra filtration hollow fiber membrane
US9821105B2 (en) * 2008-07-01 2017-11-21 Baxter International Inc. Nanoclay sorbents for dialysis
US7964697B2 (en) 2008-08-13 2011-06-21 General Electric Company Polyarylether membranes
US7985339B2 (en) * 2008-08-25 2011-07-26 General Electric Company Polyarylether compositions bearing zwitterion functionalities
EP2168614B1 (en) 2008-09-25 2012-02-15 Gambro Lundia AB Hybrid bioartificial kidney
EP2168668A1 (en) 2008-09-25 2010-03-31 Gambro Lundia AB Membrane for cell expansion
EP2177603A1 (en) 2008-09-25 2010-04-21 Gambro Lundia AB Device for renal cell expansion
EP2168666A1 (en) 2008-09-25 2010-03-31 Gambro Lundia AB Irradiated membrane for cell expansion
US7959808B2 (en) * 2008-10-31 2011-06-14 General Electric Company Polysulfone membranes methods and apparatuses
CA2745612A1 (en) * 2008-12-04 2010-06-10 The University Of Akron Polymer composition and dialysis membrane formed from the polymer composition
TW201125973A (en) * 2009-11-10 2011-08-01 Toray Industries Hollow fiber membrane module for producing chemicals and method for producing chemicals
US8277649B2 (en) * 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
KR100990168B1 (en) * 2010-07-16 2010-10-29 한국과학기술연구원 Forward osmosis membranes and method for fabricating the same
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
CN110079887B (en) * 2011-02-04 2021-12-24 弗雷塞尼斯医疗保健控股公司 Performance enhancing additives for fiber formation and polysulfone fibers
JP5758001B2 (en) * 2011-06-09 2015-08-05 旭化成メディカル株式会社 Hollow fiber membrane for blood treatment and hollow fiber membrane type blood treatment device
CN105793411B (en) 2013-11-16 2018-04-17 泰尔茂比司特公司 Cell amplification in bioreactor
CN115445457A (en) * 2014-02-06 2022-12-09 甘布罗伦迪亚股份公司 Membrane for blood purification
JP6636437B2 (en) 2014-02-06 2020-01-29 ガンブロ ルンディア アー・ベー Hemodialysis machine for blood purification
US20160339159A1 (en) * 2014-02-19 2016-11-24 Toray Industries, Inc. Hollow fiber membrane module for cleaning platelet suspension
JP6783143B2 (en) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド Passive replenishment of medium
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN109415696A (en) 2016-05-25 2019-03-01 泰尔茂比司特公司 Cell amplification
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN106039445B (en) * 2016-08-17 2019-01-04 上海佩尼医疗科技发展有限公司 A kind of superminiature dialyzer and its manufacturing method for clinical zooscopy
DE102016012730A1 (en) * 2016-10-24 2018-04-26 Fresenius Medical Care Deutschland Gmbh Method for determining a permeation property of hollow fiber membranes
US11007490B2 (en) * 2016-10-31 2021-05-18 Toyobo Co., Ltd. Cellulose acetate-based hollow fiber membrane
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656842A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
EP3677287B1 (en) 2017-08-30 2024-05-29 FUJIFILM Corporation Cell transplantation device and method for manufacturing same
EP3677289A4 (en) * 2017-08-30 2020-08-26 FUJIFILM Corporation Angiogenic agent and method for producing same
CN109157989A (en) * 2018-08-27 2019-01-08 湖南平安医械科技有限公司 Rend dialysis PVP-PSF film and modified the preparation method
CN113018546B (en) * 2021-03-17 2023-03-21 上海溯湃医疗科技有限公司 Regional citric acid anticoagulation infusion system, control method, system and medium
CN114392655A (en) * 2021-12-24 2022-04-26 苏州君康医疗科技有限公司 Preparation method of hemodialysis filtration membrane
CN114534523B (en) * 2022-03-10 2022-11-25 迈得医疗工业设备股份有限公司 Hemodialysis membrane and preparation method and application thereof
CN117491245A (en) * 2023-11-06 2024-02-02 广州美域医学检验有限公司 Method for evaluating salt permeability of resin material

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1567133A (en) * 1977-03-18 1980-05-14 Kuraray Co Sterilization of membranes
JPS57147488A (en) * 1981-03-04 1982-09-11 Kuraray Co Ltd Preparation of purified water
SE446505B (en) * 1982-11-16 1986-09-22 Gambro Dialysatoren MEMBRANE AND WAY TO MAKE THIS
US4906375A (en) * 1984-07-14 1990-03-06 Fresenius, Ag Asymmetrical microporous hollow fiber for hemodialysis
DE3426331A1 (en) * 1984-07-17 1986-01-30 6380 Bad Homburg Fresenius AG ASYMMETRIC MICROPOROUS HOLLOW FIBER FOR HAEMODIALYSIS AND METHOD FOR THE PRODUCTION THEREOF
CA1236960A (en) * 1985-04-16 1988-05-24 Shohei Masuhara Method for sterilizing artificial organs and apparatus used therefor
JPH0757825B2 (en) * 1985-04-17 1995-06-21 東レ株式会社 Polysulfone resin porous membrane
JPS61245805A (en) * 1985-04-25 1986-11-01 Daicel Chem Ind Ltd Preparation of precise filter membrane
JPS6397205A (en) * 1986-10-15 1988-04-27 Toray Ind Inc Treatment of polysulfone resin semipermeable membrane
US5198110A (en) * 1990-07-02 1993-03-30 Asahi Medical Co., Ltd. Bundle of permselective hollow fibers and a fluid separator containing the same
JP3097149B2 (en) * 1991-03-28 2000-10-10 東レ株式会社 Medical dialysis module and method of manufacturing the same
JPH0554373A (en) * 1991-08-27 1993-03-05 Sumitomo Metal Mining Co Ltd Magnetic recording medium
US5376294A (en) * 1991-08-29 1994-12-27 Nippon Shokubai Co., Ltd. Electrorhelogical fluid
US5240614A (en) * 1992-01-10 1993-08-31 Baxter International Inc. Process for removing unwanted materials from fluids and for producing biological products
US5340480A (en) * 1992-04-29 1994-08-23 Kuraray Co., Ltd. Polysulfone-based hollow fiber membrane and process for manufacturing the same
JP3117575B2 (en) * 1992-04-29 2000-12-18 株式会社クラレ Polysulfone-based hollow fiber membrane and method for producing the same
DE4217335C2 (en) * 1992-05-26 1996-01-18 Seitz Filter Werke Hydrophilic membrane and process for its manufacture
US5232601A (en) * 1992-05-29 1993-08-03 W. R. Grace & Co.-Conn. High flux hollow fiber membrane
JP2978640B2 (en) * 1992-07-06 1999-11-15 東洋機械金属株式会社 Injection molding machine
US5543465A (en) * 1993-03-19 1996-08-06 Gambro Dialysatoren Gmbh & Co. Process for the production of hydrophilic membranes

Also Published As

Publication number Publication date
KR100432464B1 (en) 2004-05-22
EP0750938B1 (en) 2005-02-16
KR100432463B1 (en) 2004-08-06
CA2180222C (en) 2006-10-10
KR970000318A (en) 1997-01-21
US6103117A (en) 2000-08-15
DE69634352D1 (en) 2005-03-24
CN1158273A (en) 1997-09-03
US5938929A (en) 1999-08-17
TW474835B (en) 2002-02-01
DE69634352T2 (en) 2006-01-12
CN1125669C (en) 2003-10-29
EP0750938A1 (en) 1997-01-02
ES2237760T3 (en) 2005-08-01
CA2180222A1 (en) 1996-12-31

Similar Documents

Publication Publication Date Title
ATE289219T1 (en) METHOD FOR PRODUCING A PARTIALLY PERMEABLE HOLLOW FIBER MEMBRANE FROM POLYSULFONE
EP1433490B1 (en) Dialyzer and method for manufacturing the same
DE69212046T3 (en) Dialysis module with selectively permeable polysulfone hollow fiber membrane and process for its manufacture
ATE109359T1 (en) DEVICE AND PROCESS FOR THE PREPARATION OF A SUBSTITUTE LIQUID.
DE3851572D1 (en) Hollow fiber polysulfone membrane and process for its manufacture.
EP0950432A1 (en) Removal of agent from cell suspension
BR8306936A (en) PERFECTED MICROFILTRATION MODULE; PERFECTED PLASMAPHERESIS PROCESS
DE3684376D1 (en) HOLLOW FIBER MEMBRANE FOR ARTIFICIAL LUNG, METHOD FOR THEIR PRODUCTION AND ARTIFICIAL LUNG USING THIS HOLLOW FIBER MEMBRANE.
WO1994007594A3 (en) Hollow fiber membrane incorporating a polyimide and process for preparing same
EA000300B1 (en) Synthetic separation diaphragm
DE69102350D1 (en) Asymmetric hollow fiber membrane made of carbon and process for its production.
DE69320000T2 (en) High flow rate hollow fiber membrane with increased transportation and process for its manufacture
US5645778A (en) Process of making a cellulose acetate semipermeable membrane
JP2001190934A (en) Hollow fiber membrane module with a little effluent
JP2004216143A (en) Dialyzer and its manufacturing method
JP3295321B2 (en) Permselective hollow fiber membrane
JP3334705B2 (en) Polysulfone-based selectively permeable hollow fiber membrane
JP2004358433A (en) Dry hollow fiber membrane and module
JPS596663B2 (en) Multi-stage filtration/reabsorption artificial kidney
DE69607240D1 (en) Dialysis filter / reactor for removal of endotoxins and method for manufacturing the filter / reactor
SE455099B (en) SET TO STABILIZE HYDRAULIC AND DIFFUSIVE PERMEABILITIES OF A WATER SEMIPERMEABLE MEMBRANE AND A WETTEABLE, SEMIPERMEABLE MEMBRANE TREATED WITH A STABILIZER
JPH10248925A (en) Selectively transmitting hollow yarn membrane
CA2222951A1 (en) Improved process for making cellulose acetate semipermeable membranes and medical products therefrom
JPH0798135B2 (en) Hollow fiber type membrane module and manufacturing method thereof
JP2008245921A (en) Hollow fiber membrane and method for manufacturing the same

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties