US20040089753A1
(en)
|
2000-06-28 |
2004-05-13 |
Holland Simon Joseph |
Wet milling process
|
WO2002055489A2
(en)
|
2000-12-27 |
2002-07-18 |
Univ Columbia |
Pim kinase-related methods
|
AU2002303191B2
(en)
*
|
2001-03-30 |
2007-01-18 |
King Pharmaceuticals, Inc. |
Pharmaceutically active compounds and methods of use
|
DE10123055A1
(de)
|
2001-05-11 |
2003-03-20 |
Gruenenthal Gmbh |
Screeningverfahren mit PIM1-Kinase oder PIM3-Kinase
|
DE10226702A1
(de)
|
2002-06-14 |
2004-09-09 |
Grünenthal GmbH |
Antisense Oligonukleotide gegen PIM1
|
WO2006078228A1
(en)
|
2002-09-16 |
2006-07-27 |
Plexxikon, Inc. |
Methods for the design of molecular scaffolds and ligands
|
WO2004024895A2
(en)
|
2002-09-16 |
2004-03-25 |
Plexxikon, Inc. |
Crystal structure of pim-1 kinase
|
CL2003002287A1
(es)
|
2002-11-25 |
2005-01-14 |
Wyeth Corp |
COMPUESTOS DERIVADOS DE TIENO[3,2-b]-PIRIDINA-6-CARBONITRILOS Y TIENEO[2,3-b]-PIRIDINA-5-CARBONITRILOS, COMPOSICION FARMACEUTICA, PROCEDIMIENTO DE PREPARACION Y COMPUESTOS INTERMEDIARIOS, Y SU USO EN EL TRATAMIENTO DEL CANCER, APOPLEJIA, OSTEOPOROSIS
|
WO2004090106A2
(en)
|
2003-04-04 |
2004-10-21 |
Vertex Pharmaceuticals Incorporated |
Crystal structures of human pim-1 kinase protein complexes and binding pockets thereof, and uses thereof in drug design
|
WO2005028624A2
(en)
|
2003-09-15 |
2005-03-31 |
Plexxikon, Inc. |
Molecular scaffolds for kinase ligand development
|
WO2005033310A1
(de)
|
2003-10-01 |
2005-04-14 |
Grünenthal GmbH |
Pim-1-spezifische dsrna-verbindungen
|
WO2006006569A1
(ja)
|
2004-07-12 |
2006-01-19 |
Nihon Nohyaku Co., Ltd. |
フェニルピリジン類又はその塩類、これらを有効成分とする除草剤及びその使用方法
|
KR101328273B1
(ko)
|
2004-12-28 |
2013-11-14 |
키넥스 파마슈티컬즈, 엘엘씨 |
세포 증식 질환의 치료를 위한 조성물 및 방법
|
MY153898A
(en)
|
2005-06-22 |
2015-04-15 |
Plexxikon Inc |
Compounds and methods for kinase modulation, and indications therefor
|
WO2007011760A2
(en)
|
2005-07-15 |
2007-01-25 |
Kalypsys, Inc. |
Inhibitors of mitotic kinesin
|
DE602005010421D1
(de)
*
|
2005-08-05 |
2008-11-27 |
Hybrigenics Sa |
Neue Cysteine Protease Hemmers und ihre therapeutische Anwendungen
|
US8053454B2
(en)
|
2005-10-06 |
2011-11-08 |
Exelixis, Inc. |
Pyridopyrimidinone inhibitors of PIM-1 and/or PIM-3
|
KR20080063806A
(ko)
|
2005-10-06 |
2008-07-07 |
쉐링 코포레이션 |
단백질 키나제 억제제로서의 피라졸로피리미딘
|
ATE517874T1
(de)
|
2005-10-21 |
2011-08-15 |
Exelixis Inc |
Pyrimidinone als modulatoren von caseinkinase ii (ck2)
|
WO2007052843A1
(ja)
|
2005-11-04 |
2007-05-10 |
Takeda Pharmaceutical Company Limited |
複素環アミド化合物およびその用途
|
US20090182003A1
(en)
|
2006-01-13 |
2009-07-16 |
President And Fellows Of Harvard College |
Methods and Compositions for Treatment Cell Proliferative Disorders
|
US20090253156A1
(en)
|
2006-05-05 |
2009-10-08 |
Perkinelmer Las, Inc. |
Mass spectrometry methods for multiplexed quantification of protein kinases and phosphatases
|
PT2041071E
(pt)
|
2006-06-29 |
2014-09-23 |
Kinex Pharmaceuticals Llc |
Composições de biarilo e processos para a regulação de uma cascata de cinases
|
CN101595084B
(zh)
|
2006-06-29 |
2013-01-02 |
金克斯医药品有限公司 |
用于调整激酶级联的二芳基组合物和方法
|
JP5252404B2
(ja)
|
2006-08-16 |
2013-07-31 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ピラジン化合物、その使用及び調製方法
|
WO2008045252A2
(en)
|
2006-10-04 |
2008-04-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Engineered integrin binding peptides
|
EP2078004B1
(en)
*
|
2006-10-31 |
2015-02-25 |
Merck Sharp & Dohme Corp. |
2-aminothiazole-4-carboxylic amides as protein kinase inhibitors
|
MY146474A
(en)
|
2006-11-06 |
2012-08-15 |
Supergen Inc |
Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors
|
WO2008082839A2
(en)
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
WO2008082840A1
(en)
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
MX2009009304A
(es)
|
2007-03-01 |
2009-11-18 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso.
|
US20100144751A1
(en)
|
2007-03-28 |
2010-06-10 |
Array Biopharma Inc. |
IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS
|
MY157724A
(en)
|
2007-04-03 |
2016-07-15 |
Array Biopharma Inc |
IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS
|
KR20100017359A
(ko)
|
2007-04-25 |
2010-02-16 |
엑셀리시스, 인코포레이티드 |
카제인 키나제 ⅱ (ck2)조절제로서의 피리미디논
|
CN102317266A
(zh)
|
2007-04-25 |
2012-01-11 |
埃克塞利希斯股份有限公司 |
作为pim调节剂的6-苯基嘧啶酮类
|
BRPI0814441A2
(pt)
|
2007-07-19 |
2015-07-14 |
Schering Corp |
Compostos de amida heterocíclica como inibidores de proteína cinase
|
JP2010535201A
(ja)
|
2007-07-31 |
2010-11-18 |
シェーリング コーポレイション |
抗癌治療としての抗有糸分裂薬およびオーロラキナーゼ阻害薬
|
US8853406B2
(en)
*
|
2007-08-06 |
2014-10-07 |
Janssen Pharmaceutica Nv |
Substituted phenylenediamines as inhibitors of the interaction between MDM2 and P53
|
CA2743756A1
(en)
|
2007-11-15 |
2009-05-22 |
Musc Foundation For Research Development |
Inhibitors of pim protein kinases, compositions, and methods for treating cancer
|
JP2011503207A
(ja)
|
2007-11-16 |
2011-01-27 |
サン ディエゴ ステート ユニバーシティ リサーチ ファウンデーション |
循環系細胞におけるpim−1活性を操作するための組成物および方法
|
MX2010009445A
(es)
|
2008-02-29 |
2011-05-25 |
Cylene Pharmaceuticals Inc |
Moduladores de proteina kinasa.
|
US8168794B2
(en)
|
2008-03-03 |
2012-05-01 |
Novartis Ag |
Pim kinase inhibitors and methods of their use
|
AR070531A1
(es)
|
2008-03-03 |
2010-04-14 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso
|
BRPI0912337A2
(pt)
|
2008-05-12 |
2019-09-24 |
Amnestix Inc |
composto método para melhorar memória em paciente, e, método para tratar condições
|
US8124649B2
(en)
|
2008-06-30 |
2012-02-28 |
Cylene Pharmaceuticals, Inc. |
Oxindole compounds
|
TWI461423B
(zh)
|
2008-07-02 |
2014-11-21 |
Astrazeneca Ab |
用於治療Pim激酶相關病狀及疾病之噻唑啶二酮化合物
|
FR2933409B1
(fr)
|
2008-07-03 |
2010-08-27 |
Centre Nat Rech Scient |
NOUVEAUX PYRROLO °2,3-a! CARBAZOLES ET LEUR UTILISATION COMME INHIBITEURS DES KINASES PIM
|
WO2010022081A1
(en)
|
2008-08-19 |
2010-02-25 |
Array Biopharma Inc. |
Triazolopyridine compounds as pim kinase inhibitors
|
TWI496779B
(zh)
|
2008-08-19 |
2015-08-21 |
Array Biopharma Inc |
作為pim激酶抑制劑之三唑吡啶化合物
|
JP5584215B2
(ja)
|
2008-09-02 |
2014-09-03 |
ノバルティス アーゲー |
ヘテロ環pimキナーゼ阻害剤
|
WO2010026121A1
(en)
|
2008-09-02 |
2010-03-11 |
Novartis Ag |
Bicyclic kinase inhibitors
|
CN103333157A
(zh)
|
2008-09-02 |
2013-10-02 |
诺瓦提斯公司 |
作为激酶抑制剂的吡啶甲酰胺衍生物
|
LT3372605T
(lt)
|
2008-10-22 |
2022-02-10 |
Array Biopharma, Inc. |
Pakeistieji pirazolo[1,5-a]pirimidino junginiai, kaip trk kinazės inhibitoriai
|
GB0821307D0
(en)
|
2008-11-21 |
2008-12-31 |
Summit Corp Plc |
Compounds for treatment of duchenne muscular dystrophy
|
ES2539620T3
(es)
|
2008-12-19 |
2015-07-02 |
Cephalon, Inc. |
Pirrolotriazina como inhibidor de ALK y de JAK2
|
CA3025627C
(en)
*
|
2009-04-20 |
2021-08-31 |
Auspex Pharmaceuticals, Inc. |
Piperidine inhibitors of janus kinase 3
|
WO2010135401A2
(en)
|
2009-05-19 |
2010-11-25 |
San Diego State University Foundation |
Kinase-mediated cytoprotection and enhanced cellular engraftment and persistence
|
WO2010135571A1
(en)
|
2009-05-20 |
2010-11-25 |
Cylene Pharmaceuticals, Inc. |
Novel protein kinase modulators
|
CN102458412A
(zh)
|
2009-05-20 |
2012-05-16 |
赛林药物股份有限公司 |
作为激酶抑制剂的吡唑并嘧啶和相关杂环
|
MY156727A
(en)
|
2009-05-22 |
2016-03-15 |
Incyte Corp |
N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
|
WO2010148351A1
(en)
|
2009-06-18 |
2010-12-23 |
Cylene Pharmaceuticals, Inc. |
Rhodanines and related heterocycles as kinase inhibitors
|
RS53494B9
(sr)
|
2009-06-29 |
2020-11-30 |
Incyte Holdings Corp |
Pirimidinoni kao inhibitori pi3k
|
US20110065698A1
(en)
|
2009-08-26 |
2011-03-17 |
Cylene Pharmaceuticals, Inc. |
Novel protein kinase modulators
|
US9249145B2
(en)
|
2009-09-01 |
2016-02-02 |
Incyte Holdings Corporation |
Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
|
CN102625807B
(zh)
|
2009-09-08 |
2016-03-09 |
霍夫曼-拉罗奇有限公司 |
4-取代的吡啶-3-基-甲酰胺化合物和使用方法
|
US8435976B2
(en)
|
2009-09-08 |
2013-05-07 |
F. Hoffmann-La Roche |
4-substituted pyridin-3-yl-carboxamide compounds and methods of use
|
US20110071115A1
(en)
|
2009-09-11 |
2011-03-24 |
Cylene Pharmaceuticals, Inc. |
Pharmaceutically useful heterocycle-substituted lactams
|
AU2010295622A1
(en)
|
2009-09-16 |
2012-05-10 |
Cylene Pharmaceuticals, Inc. |
Tricyclic compounds and pharmaceutical uses thereof
|
MX2012003322A
(es)
|
2009-09-16 |
2012-07-23 |
Cylene Pharmaceuticals Inc |
Moduladores novedosos de proteina cinasa triciclica.
|
EP2493313B1
(en)
|
2009-10-29 |
2017-12-13 |
Genosco |
Kinase inhibitors
|
EP2332917B1
(en)
|
2009-11-11 |
2012-08-01 |
Sygnis Bioscience GmbH & Co. KG |
Compounds for PIM kinase inhibition and for treating malignancy
|
EP2499117B1
(en)
|
2009-11-12 |
2015-10-21 |
Selvita S.A. |
A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent
|
JP5740409B2
(ja)
|
2009-11-13 |
2015-06-24 |
ジェノスコ |
キナーゼ阻害剤
|
WO2011063398A1
(en)
|
2009-11-23 |
2011-05-26 |
Cylene Pharamaceuticals, Inc. |
Polymorphs and salts of a kinase inhibitor
|
ES2629170T3
(es)
|
2009-12-04 |
2017-08-07 |
Senhwa Biosciences, Inc. |
Pirazolopirimidinas y heterociclos relacionados como inhibidores de CK2
|
US8759359B2
(en)
|
2009-12-18 |
2014-06-24 |
Incyte Corporation |
Substituted heteroaryl fused derivatives as PI3K inhibitors
|
WO2011075613A1
(en)
|
2009-12-18 |
2011-06-23 |
Sanofi |
Azaindole derivatives, their preparation and their therapeutic application
|
TW201130842A
(en)
|
2009-12-18 |
2011-09-16 |
Incyte Corp |
Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors
|
EP2516425B1
(en)
|
2009-12-23 |
2015-09-02 |
Jasco Pharmaceuticals LLC |
Aminopyrimidine kinase inhibitors
|
GB201002861D0
(en)
|
2010-02-19 |
2010-04-07 |
Cxr Biosciences Ltd |
Compositions
|
KR102283091B1
(ko)
|
2010-03-10 |
2021-07-30 |
인사이트 홀딩스 코포레이션 |
Jak1 저해제로서의 피페리딘4일 아제티딘 유도체
|
MA34234B1
(fr)
|
2010-04-07 |
2013-05-02 |
Hoffmann La Roche |
Composes pyrazol-4-yl-heterocyclyle-carboxamide et leurs procedes d'utilisation
|
WO2011130342A1
(en)
|
2010-04-14 |
2011-10-20 |
Incyte Corporation |
FUSED DERIVATIVES AS ΡI3Κδ INHIBITORS
|
WO2011163195A1
(en)
|
2010-06-21 |
2011-12-29 |
Incyte Corporation |
Fused pyrrole derivatives as pi3k inhibitors
|
US20130109682A1
(en)
|
2010-07-06 |
2013-05-02 |
Novartis Ag |
Cyclic ether compounds useful as kinase inhibitors
|
CN105367577B
(zh)
|
2010-07-13 |
2019-04-23 |
弗·哈夫曼-拉罗切有限公司 |
作为irak4调节剂的吡唑并[1,5a]嘧啶和噻吩并[3,2b]嘧啶衍生物
|
US8227773B2
(en)
|
2010-07-29 |
2012-07-24 |
Axcelis Technologies, Inc. |
Versatile beam glitch detection system
|
US8791136B2
(en)
|
2010-07-29 |
2014-07-29 |
Rigel Pharmaceuticals, Inc. |
Substituted pyridine, pyridazine, pyrazine and pyrimidine compounds and methods for using the same
|
EP2637650A2
(en)
|
2010-11-10 |
2013-09-18 |
National Jewish Health |
Methods to test allergic conditions
|
WO2012065297A1
(en)
|
2010-11-16 |
2012-05-24 |
Impact Therapeutics, Inc. |
3-ARYL-6-ARYL-[1,2,4]TRIAZOLO[4,3-a]PYRIDINES AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF
|
BR112013012502A2
(pt)
|
2010-11-19 |
2019-03-06 |
Incyte Corporation |
pirrolopiridina ciclobutil substituída e derivados de pirrolopirimidina derivativos como inibidores de jak
|
CA2818545C
(en)
|
2010-11-19 |
2019-04-16 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
|
JP2014500277A
(ja)
|
2010-12-09 |
2014-01-09 |
アムジエン・インコーポレーテツド |
Pim阻害剤としての二環式化合物
|
EP2614065B1
(en)
|
2010-12-17 |
2017-04-19 |
Nerviano Medical Sciences S.r.l. |
Substituted pyrazolo-quinazoline derivatives as kinase inhibitors
|
WO2012087881A1
(en)
|
2010-12-20 |
2012-06-28 |
Incyte Corporation |
N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
|
US8916577B2
(en)
|
2011-01-26 |
2014-12-23 |
Nerviano Medical Sciences S.R.L. |
Tricyclic derivatives, process for their preparation and their use as kinase inhibitors
|
BR112013018515B1
(pt)
|
2011-01-26 |
2021-06-29 |
Nerviano Medical Sciences S.R.I |
Derivados de pirrol tricíclico, processo para sua preparação e seu uso como inibidores da quinase
|
AR085489A1
(es)
|
2011-02-25 |
2013-10-09 |
Array Biopharma Inc |
Derivados de triazolopiridinas, composiciones farmaceuticas que los contienen, proceso para prepararlos, intermediarios de dicho proceso y uso de los mismos para el tratamiento de enfermedades autoinmunes e inflamatorias
|
EP2681197A1
(en)
|
2011-03-04 |
2014-01-08 |
Novartis AG |
Tetrasubstituted cyclohexyl compounds as kinase inhibitors
|
UY33930A
(es)
|
2011-03-04 |
2012-10-31 |
Novartis Ag |
Inhibidores novedosos de quinasas
|
WO2012125629A1
(en)
|
2011-03-14 |
2012-09-20 |
Incyte Corporation |
Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
|
JP2014510105A
(ja)
|
2011-03-22 |
2014-04-24 |
アムジエン・インコーポレーテツド |
Pim阻害剤としてのアゾール化合物
|
US9126948B2
(en)
|
2011-03-25 |
2015-09-08 |
Incyte Holdings Corporation |
Pyrimidine-4,6-diamine derivatives as PI3K inhibitors
|
EA201391239A1
(ru)
|
2011-04-05 |
2014-03-31 |
Пфайзер Лимитед |
Пирроло[2,3-d]пиримидиновые производные в качестве ингибиторов тропомиозин-связанных киназ
|
US9284298B2
(en)
|
2011-04-11 |
2016-03-15 |
Nerviano Medical Sciences S.R.L. |
Pyrazolyl-pyrimidine derivatives as kinase inhibitors
|
CA2832865C
(en)
|
2011-04-22 |
2021-05-11 |
Jasco Pharmaceuticals, LLC |
Aminopyrimidine kinase inhibitors
|
GB201107197D0
(en)
|
2011-04-28 |
2011-06-15 |
Cxr Biosciences Ltd |
Compounds
|
GB201107176D0
(en)
|
2011-04-28 |
2011-06-15 |
Cxr Biosciences Ltd |
Pyrrolnitrin derivatives
|
CA2834166A1
(en)
|
2011-04-29 |
2012-11-01 |
Amgen Inc. |
Bicyclic pyridazine compounds as pim inhibitors
|
CN103687858B
(zh)
|
2011-05-17 |
2017-11-21 |
拜耳知识产权有限责任公司 |
作为mknk1激酶抑制剂的氨基取代的咪唑并哒嗪
|
AU2012257513B2
(en)
|
2011-05-19 |
2017-05-11 |
Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) |
Macrocyclic compounds as protein kinase inhibitors
|
KR20140048891A
(ko)
|
2011-05-27 |
2014-04-24 |
템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 |
치환된 2-벤질리덴-2H-벤조[b][1,4]티아진-3(4H)-온, 이의 유도체, 및 이의 치료적 용도
|
ES2625854T3
(es)
|
2011-06-01 |
2017-07-20 |
Bayer Intellectual Property Gmbh |
Aminoimidazopiridazinas sustituidas
|
WO2012170827A2
(en)
|
2011-06-08 |
2012-12-13 |
Cylene Pharmaceuticals, Inc. |
Pyrazolopyrimidines and related heterocycles as ck2 inhibitors
|
MY165963A
(en)
|
2011-06-20 |
2018-05-18 |
Incyte Holdings Corp |
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
|
US9284319B2
(en)
|
2011-06-22 |
2016-03-15 |
Bayer Intellectual Property Gmbh |
Heterocyclyl aminoimidazopyridazines
|
ES2834093T3
(es)
|
2011-07-21 |
2021-06-16 |
Sumitomo Dainippon Pharma Oncology Inc |
Inhibidores de proteína quinasa heterocíclicos
|
CN102924444B
(zh)
|
2011-08-11 |
2015-07-08 |
上海吉铠医药科技有限公司 |
Pim激酶抑制剂及其制备方法与在制药中的应用
|
MX355852B
(es)
|
2011-08-12 |
2018-05-02 |
Hoffmann La Roche |
Compuestos de pirazolo [3,4-c] piridina y métodos de uso.
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為jak抑制劑之環己基氮雜環丁烷衍生物
|
JP5843524B2
(ja)
|
2011-09-02 |
2016-01-13 |
キヤノン株式会社 |
有機無機複合組成物、有機無機複合材料、光学素子および積層型回折光学素子
|
IL299533A
(en)
|
2011-09-02 |
2023-02-01 |
Incyte Holdings Corp |
Heterocycloamines as P13K inhibitors
|
UA117092C2
(uk)
|
2011-09-06 |
2018-06-25 |
Байєр Інтеллектуал Проперті Гмбх |
Амінозаміщені імідазопіридазини
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
US8735528B1
(en)
*
|
2011-09-20 |
2014-05-27 |
The United States Of America As Represented By The Secretary Of The Air Force |
Two-photon absorbing cross-linked polyurethanes containing diphenylamino-dialkylfluorene-1,3,5-triazine units
|
EP2758400A1
(en)
|
2011-09-23 |
2014-07-30 |
Bayer Intellectual Property GmbH |
Substituted imidazopyridazines
|
SG2014012579A
(en)
|
2011-09-27 |
2014-04-28 |
Hoffmann La Roche |
Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use
|
JP5998223B2
(ja)
|
2011-10-07 |
2016-09-28 |
ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ |
キナーゼ阻害剤としての置換3,4−ジヒドロピロロ[1,2−a]ピラジン−1(2H)−オン誘導体
|
WO2013050448A1
(en)
|
2011-10-07 |
2013-04-11 |
Nerviano Medical Sciences S.R.L. |
4-ALKYL SUBSTITUTED 3,4-DIHYDROPYRROLO[1,2-a]PYRAZIN-1(2H)-ONE DERIVATIVES AS KINASES INHIBITORS
|
MX347191B
(es)
|
2011-11-04 |
2017-04-19 |
Jasco Pharmaceuticals Llc |
Inhibidores de aminopirimidina cinasa.
|
US9394297B2
(en)
|
2012-02-28 |
2016-07-19 |
Amgen Inc. |
Amides as pim inhibitors
|
US9340549B2
(en)
|
2012-03-05 |
2016-05-17 |
Amgen Inc. |
Oxazolidinone compounds and derivatives thereof
|
ES2663609T3
(es)
|
2012-03-29 |
2018-04-16 |
Bayer Intellectual Property Gmbh |
Imidazopiridazinas amino-sustituidas
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
CN104321326B
(zh)
|
2012-04-04 |
2017-05-31 |
拜耳医药股份有限公司 |
氨基取代的咪唑并哒嗪
|
SG11201406757SA
(en)
|
2012-04-26 |
2014-11-27 |
Bristol Myers Squibb Co |
Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation
|
AU2013254307B2
(en)
|
2012-04-27 |
2016-05-26 |
Novartis Ag |
Cyclic bridgehead ether DGAT1 inhibitors
|
KR102165177B1
(ko)
|
2012-05-09 |
2020-10-13 |
바이오젠 엠에이 인코포레이티드 |
핵 수송 조절인자 및 이의 용도
|
MA37519B1
(fr)
|
2012-05-15 |
2017-03-31 |
Novartis Ag |
Composés et compositions pour inhiber l'activité d'abl1, abl2 et bcr-abl1
|
WO2013173720A1
(en)
|
2012-05-18 |
2013-11-21 |
Incyte Corporation |
Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
|
TW201408641A
(zh)
|
2012-05-21 |
2014-03-01 |
Novartis Ag |
可作爲激酶抑制劑之新穎環取代n-吡啶基醯胺
|
AU2013266393B2
(en)
|
2012-05-22 |
2017-09-28 |
Idenix Pharmaceuticals Llc |
D-amino acid compounds for liver disease
|
TWI568722B
(zh)
|
2012-06-15 |
2017-02-01 |
葛蘭馬克製藥公司 |
作爲mPGES-1抑制劑之三唑酮化合物
|
RU2665462C2
(ru)
|
2012-06-27 |
2018-08-30 |
Ф. Хоффманн-Ля Рош Аг |
Соединения 5-азаиндазола и способы их применения
|
AR092348A1
(es)
|
2012-07-11 |
2015-04-15 |
Hoffmann La Roche |
DERIVADOS DE ARIL-SULTAMO COMO MODULADORES DE RORc
|
TW201414737A
(zh)
|
2012-07-13 |
2014-04-16 |
必治妥美雅史谷比公司 |
作爲激酶抑制劑之咪唑并三□甲腈
|
WO2014022752A1
(en)
|
2012-08-03 |
2014-02-06 |
Amgen Inc. |
Macrocycles as pim inhibitors
|
WO2014033630A1
(en)
|
2012-08-31 |
2014-03-06 |
Novartis Ag |
Novel aminothiazole carboxamides as kinase inhibitors
|
WO2014033631A1
(en)
|
2012-08-31 |
2014-03-06 |
Novartis Ag |
N-(3-pyridyl) biarylamides as kinase inhibitors
|
CN103664878A
(zh)
|
2012-09-12 |
2014-03-26 |
山东亨利医药科技有限责任公司 |
杂芳环及其衍生物类酪氨酸激酶抑制剂
|
CA2884548A1
(en)
|
2012-09-14 |
2014-03-20 |
AbbVie Deutschland GmbH & Co. KG |
Tricyclic quinoline and quinoxaline derivatives
|
US9328106B2
(en)
|
2012-09-26 |
2016-05-03 |
Genentech, Inc. |
Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use
|
WO2014053568A1
(en)
|
2012-10-02 |
2014-04-10 |
Sanofi |
Indolyldihydroimidazopyrimidinone derivatives, preparation thereof and therapeutic use thereof
|
SI2909195T1
(sl)
|
2012-10-16 |
2017-10-30 |
Janssen Sciences Ireland Uc |
RSV protivirusni sestavki
|
BR112015009942A2
(pt)
|
2012-11-01 |
2017-07-11 |
Incyte Corp |
derivados de tiofeno fundidos tricíclicos como inibidores de jak
|
JP2015537017A
(ja)
|
2012-11-19 |
2015-12-24 |
バイエル ファーマ アクチエンゲゼルシャフト |
アミノイミダゾピリダジン類
|
WO2014079011A1
(en)
|
2012-11-22 |
2014-05-30 |
Agios Pharmaceuticals, Inc. |
Heterocyclic compounds for inhibiting glutaminase and their methods of use
|
NZ731337A
(en)
|
2012-12-07 |
2019-02-22 |
Vertex Pharma |
Compounds useful as inhibitors of atr kinase
|
EP3388441A1
(en)
|
2012-12-18 |
2018-10-17 |
Vertex Pharmaceuticals Incorporated |
Mannose derivatives for treating bacterial infections
|
MX2015007936A
(es)
|
2012-12-19 |
2016-03-11 |
Novartis Ag |
Inhibidores de autotaxina.
|
US20150336960A1
(en)
|
2012-12-19 |
2015-11-26 |
Novartis Ag |
Aryl-substituted fused bicyclic pyridazine compounds
|
RS54873B1
(sr)
|
2012-12-21 |
2016-10-31 |
Gilead Sciences |
Policiklična-karbamoilpiridonska jedinjenja i njihova farmaceutska upotreba
|
PE20151501A1
(es)
|
2012-12-21 |
2015-11-08 |
Epizyme Inc |
Inhibidores de prmt5 y sus usos
|
FR3000569B1
(fr)
|
2013-01-03 |
2015-02-13 |
Peugeot Citroen Automobiles Sa |
Dispositif d'eclairage a ecran a bord(s) lumineux
|
US9278950B2
(en)
|
2013-01-14 |
2016-03-08 |
Incyte Corporation |
Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
|
AR094664A1
(es)
*
|
2013-01-15 |
2015-08-19 |
Incyte Corp |
Compuestos de tiazolcarboxamidas y piridinacarboxamida utiles como inhibidores de quinasa pim
|
TW202214254A
(zh)
|
2013-03-01 |
2022-04-16 |
美商英塞特控股公司 |
吡唑并嘧啶衍生物治療PI3Kδ相關病症之用途
|
NZ711976A
(en)
|
2013-03-06 |
2019-01-25 |
Incyte Holdings Corp |
Processes and intermediates for making a jak inhibitor
|
JO3383B1
(ar)
|
2013-03-14 |
2019-03-13 |
Lilly Co Eli |
مثبطات cdc7
|
MX2015012456A
(es)
|
2013-03-15 |
2016-02-03 |
Plexxikon Inc |
Compuestos heterociclicos y usos de los mismos.
|
TWI689489B
(zh)
|
2013-03-15 |
2020-04-01 |
英商邊緣生物科技有限公司 |
用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物
|
EP3581576B1
(en)
|
2013-03-15 |
2022-01-26 |
Incyte Holdings Corporation |
Tricyclic heterocycles as bet protein inhibitors for use in the treatment of a proliferative disease in combination with a janus kinase inhibitor
|
UY35421A
(es)
|
2013-03-15 |
2014-10-31 |
Nihon Nohyaku Co Ltd |
Compuesto heterocíclico condensado o su sal, insecticida agrícola u hortícola que comprende el comp uesto y método de uso del insecticida
|
EA201591426A1
(ru)
|
2013-03-15 |
2016-02-29 |
Глобал Блад Терапьютикс, Инк. |
Соединения и их применения для модуляции гемоглобина
|
KR20190041548A
(ko)
|
2013-03-15 |
2019-04-22 |
글로벌 블러드 테라퓨틱스, 인크. |
헤모글로빈 조정을 위한 화합물 및 이의 용도
|
AR095443A1
(es)
|
2013-03-15 |
2015-10-14 |
Fundación Centro Nac De Investig Oncológicas Carlos Iii |
Heterociclos condensados con acción sobre atr
|
RS57188B1
(sr)
|
2013-03-15 |
2018-07-31 |
Japan Tobacco Inc |
Jedinjenje pirazol-amida i njegove medicinske upotrebe
|
JO3279B1
(ar)
|
2013-03-15 |
2018-09-16 |
Respivert Ltd |
مشتقات 2-((4- امينو -3- (3- فلورو-5- هيدروكسي فينيل)-h1- بيرازولو [d-3,4] بيرمدين-1-يل )ميثيل )- 3- (2- تراي فلورو ميثيل ) بينزيل ) كوينازولين -4 (h3)- واحد واستخدامها كمثبطات فوسفواينوسيتايد 3- كاينيز
|
EP3640249A1
(en)
|
2013-03-15 |
2020-04-22 |
Dow AgroSciences LLC |
4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their use as herbicides
|
US20160052926A1
(en)
|
2013-03-15 |
2016-02-25 |
Hutchison Medipharma Limited |
Novel pyrimidine and pyridine compounds and usage thereof
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
TWI689490B
(zh)
|
2013-03-15 |
2020-04-01 |
英商邊緣生物科技有限公司 |
用於治療纖維化之經取代之芳族化合物及相關方法
|
EA029309B1
(ru)
|
2013-03-15 |
2018-03-30 |
Идорсиа Фармасьютиклз Лтд |
Производные пиридин-4-ила в качестве агонистов s1p/edg1
|
US20140275108A1
(en)
|
2013-03-15 |
2014-09-18 |
Galderma Research & Development |
Novel benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
|
SG10201801069QA
(en)
|
2013-08-07 |
2018-03-28 |
Incyte Corp |
Sustained release dosage forms for a jak1 inhibitor
|
US9556197B2
(en)
|
2013-08-23 |
2017-01-31 |
Incyte Corporation |
Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors
|
EA201691745A1
(ru)
|
2014-02-28 |
2016-12-30 |
Инсайт Корпорейшн |
Ингибиторы jak1 для лечения миелодиспластических синдромов
|
EA201692011A1
(ru)
|
2014-04-08 |
2017-01-30 |
Инсайт Корпорейшн |
Лечение b-клеточных злокачественных новообразований с применением комбинации ингибиторов jak и pi3k
|
CR20160553A
(es)
|
2014-04-30 |
2017-04-25 |
Incyte Corp |
Procesos para preparar un inhibidor de jak1 y nuevas formas de este
|
US9498467B2
(en)
|
2014-05-30 |
2016-11-22 |
Incyte Corporation |
Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
|
WO2015191677A1
(en)
|
2014-06-11 |
2015-12-17 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
|
WO2016010897A1
(en)
|
2014-07-14 |
2016-01-21 |
Incyte Corporation |
Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
|
US9580418B2
(en)
|
2014-07-14 |
2017-02-28 |
Incyte Corporation |
Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
|
WO2016196244A1
(en)
|
2015-05-29 |
2016-12-08 |
Incyte Corporation |
Pyridineamine compounds useful as pim kinase inhibitors
|
AR105967A1
(es)
|
2015-09-09 |
2017-11-29 |
Incyte Corp |
Sales de un inhibidor de pim quinasa
|
US9920032B2
(en)
|
2015-10-02 |
2018-03-20 |
Incyte Corporation |
Heterocyclic compounds useful as pim kinase inhibitors
|