ZA99812B - Process for preparing (R)-2-bromo-3-phenyl-propionic acid. - Google Patents

Process for preparing (R)-2-bromo-3-phenyl-propionic acid.

Info

Publication number
ZA99812B
ZA99812B ZA9900812A ZA99812A ZA99812B ZA 99812 B ZA99812 B ZA 99812B ZA 9900812 A ZA9900812 A ZA 9900812A ZA 99812 A ZA99812 A ZA 99812A ZA 99812 B ZA99812 B ZA 99812B
Authority
ZA
South Africa
Prior art keywords
phenyl
bromo
preparing
propionic acid
alanine
Prior art date
Application number
ZA9900812A
Inventor
Pietro Allegrini
Giorgio Soriato
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of ZA99812B publication Critical patent/ZA99812B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

It is described a process for preparing (R)-2-bromo-3-phenyl-propionic acid starting from (D)-phenyl-alanine, sodium nitrite and concentrated hydrobromic acid in a mixture of an aqueous solvent and a solvent selected from the group consisting of halogenated hydrocarbons and aromatic hydrocarbons.
ZA9900812A 1998-02-18 1999-02-02 Process for preparing (R)-2-bromo-3-phenyl-propionic acid. ZA99812B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98MI000302A IT1298268B1 (en) 1998-02-18 1998-02-18 PROCEDURE FOR THE PREPARATION OF THE (S) -2-BROMO-3-PHENYL-PROPIONIC ACID

Publications (1)

Publication Number Publication Date
ZA99812B true ZA99812B (en) 1999-08-02

Family

ID=11378968

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9900812A ZA99812B (en) 1998-02-18 1999-02-02 Process for preparing (R)-2-bromo-3-phenyl-propionic acid.

Country Status (10)

Country Link
US (1) US6103931A (en)
EP (1) EP1056707B1 (en)
AT (1) ATE285393T1 (en)
CA (1) CA2321001A1 (en)
DE (1) DE69922792D1 (en)
HU (1) HUP0100253A3 (en)
IL (1) IL137120A (en)
IT (1) IT1298268B1 (en)
WO (1) WO1999042431A1 (en)
ZA (1) ZA99812B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1014353C2 (en) * 2000-02-11 2001-08-15 Dsm Nv Process for the preparation of (R) -2-bromo-3-phenylpropanoic acid.
ATE275129T1 (en) * 2000-03-30 2004-09-15 Ajinomoto Kk METHOD FOR PRODUCING AROMATIC ACYLTHIOCARBOXIC ACID DERIVATIVES
US6620600B2 (en) * 2000-09-15 2003-09-16 Bristol-Myers Squibb Co. Enzymatic resolution of aryl and thio-substituted acids
US7388098B2 (en) 2000-09-29 2008-06-17 Bristol-Myers Squibb Company Dynamic resolution of isomers and resolved isomers
WO2003014056A1 (en) * 2001-08-08 2003-02-20 Kaneka Corporation Process for producing optically active 2-substituted carboxylic acid
JPWO2003066563A1 (en) * 2002-02-04 2005-05-26 株式会社カネカ Process for producing optically active 2-halogenocarboxylic acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4339600A (en) * 1976-05-10 1982-07-13 E. R. Squibb & Sons, Inc. Compounds for alleviating angiotensin related hypertension
JPS56158732A (en) * 1980-05-14 1981-12-07 Toyo Soda Mfg Co Ltd Preparation of alpha-halogeno-beta-phenylpropionic acid
FR2679564A1 (en) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med NOVEL ACYLMERCAPTOALCANOLDIPEPTIDES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
HU223663B1 (en) * 1992-05-15 2004-11-29 Merrel Dow Pharmaceuticals Inc. 9-[2-(acetyl-thio-phenyl)-propanoyl-amino]-pyridazo[1,2-a][1,2]diazepine derivatives, use of them, process for preparing them and pharmaceutical compositions of enkephalinase and ace inhibitor activity..
US5238932A (en) * 1992-05-20 1993-08-24 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
US5525723A (en) * 1993-11-18 1996-06-11 Bristol-Myers Squibb Co. Compounds containing a fused multiple ring lactam

Also Published As

Publication number Publication date
ATE285393T1 (en) 2005-01-15
CA2321001A1 (en) 1999-08-26
HUP0100253A2 (en) 2001-05-28
WO1999042431A1 (en) 1999-08-26
IT1298268B1 (en) 1999-12-20
DE69922792D1 (en) 2005-01-27
EP1056707A1 (en) 2000-12-06
US6103931A (en) 2000-08-15
ITMI980302A1 (en) 1999-08-18
IL137120A (en) 2005-06-19
IL137120A0 (en) 2001-06-14
EP1056707B1 (en) 2004-12-22
HUP0100253A3 (en) 2002-09-30

Similar Documents

Publication Publication Date Title
WO2001098331A3 (en) Glucagon-like peptide-1 analogs
AU2417201A (en) New use of a bioadhesive composition comprising a polyphenolic protein
MX9704433A (en) Novel process.
AU3877500A (en) Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof
WO2000061127A3 (en) Use of insulin sensitisers for improving ketosis
AU4370999A (en) New dipeptidyl peptidase iv effectors
AU6154000A (en) Process for making cold-setting flexible foams, polyol composition and reaction system useful therefor, foams thus obtained
AU6770100A (en) Adjustable-backset latch system for locksets, and method
AU4561900A (en) Process for making low density foams, polyol composition and reaction system useful therefor
IL137120A (en) Process for preparing (r)-2-bromo-3-phenyl-propionic acid
AU2001249438A1 (en) Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
AU1722399A (en) Foams comprising hfc-134 and a low solubility co-blowing agent and a process formaking
AU8631698A (en) A process for the preparation of tetraazamacrocycles
GB9505996D0 (en) High stability, organic tanning process
AU8979498A (en) Process for preparing 2-cyanoindan-1-ones
EP1277720A3 (en) Fluorination of 1,1,1,3,3-pentachloropropane
AU6597100A (en) Triketone compounds, process for producing the same and herbicides containing the same
AU2001249534A1 (en) Sulfonate-containing polyurethane dispersions via non-solvent process
AU3520895A (en) Process for preparing selegilin
WO2000012473A8 (en) PROCESS FOR THE PRODUCTION OF N-PROTECTED AZETIDINE-2-CARBOXYLIC ACIDS (AzeOHs)
CA2250066A1 (en) Process for alkylating and smiles rearrangement of hydroxy aromatics
AU7213498A (en) A process for the preparation of an aminoalcohol
ZA976212B (en) Process for nitrosation of a phenolic compound substituted with an electron-withdrawing group and use thereof.
AU2001272930A1 (en) Process for recovering helium using an eductor
EP0937718A4 (en) Antibiotic tkr2648 and process for producing the same