ZA99681B - 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled and unlabelled form and use of 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled or unlabelled form in diagnostic methods. - Google Patents

8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled and unlabelled form and use of 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled or unlabelled form in diagnostic methods.

Info

Publication number
ZA99681B
ZA99681B ZA9900681A ZA99681A ZA99681B ZA 99681 B ZA99681 B ZA 99681B ZA 9900681 A ZA9900681 A ZA 9900681A ZA 99681 A ZA99681 A ZA 99681A ZA 99681 B ZA99681 B ZA 99681B
Authority
ZA
South Africa
Prior art keywords
azabicyclo
labelled
oct
ene derivatives
unlabelled form
Prior art date
Application number
ZA9900681A
Inventor
Peter Moldt
Jorgen Scheel-Kruger
Elsebet Ostergaard Nielsen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of ZA99681B publication Critical patent/ZA99681B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9900681A 1998-01-28 1999-01-28 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled and unlabelled form and use of 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled or unlabelled form in diagnostic methods. ZA99681B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK12598 1998-01-28

Publications (1)

Publication Number Publication Date
ZA99681B true ZA99681B (en) 1999-09-27

Family

ID=8090037

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9900681A ZA99681B (en) 1998-01-28 1999-01-28 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled and unlabelled form and use of 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled or unlabelled form in diagnostic methods.

Country Status (5)

Country Link
EP (1) EP1068204A1 (en)
JP (1) JP2002501921A (en)
AU (1) AU2609999A (en)
WO (1) WO1999038866A1 (en)
ZA (1) ZA99681B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000044746A1 (en) * 1999-01-28 2000-08-03 Neurosearch A/S Novel azabicyclo derivatives and their use
EP1757600A2 (en) * 2000-10-13 2007-02-28 NeuroSearch A/S Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128118A (en) * 1990-08-09 1992-07-07 Research Triangle Institute Cocaine receptor binding ligands
GB9019973D0 (en) * 1990-09-12 1990-10-24 Wyeth John & Brother Ltd Azabicyclic derivatives
ES2138601T3 (en) * 1991-11-15 2000-01-16 Res Triangle Inst COCAINA RECEIVER UNION LEAGUARDS.
AU672052B2 (en) * 1992-12-23 1996-09-19 Neurosearch A/S Antidepressant and antiparkinsonian compounds
FI96603C (en) * 1994-12-30 1996-07-25 Joergen Bergman A new radiolabeled compound, a mixture containing the compound and a process for their preparation
NZ320216A (en) * 1995-10-13 1999-05-28 Neurosearch As 8-azabicyclo[3.2.1]oct-2-ene derivatives, their preparation and use
US5726189A (en) * 1996-05-03 1998-03-10 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Method for imaging nicotinic acetylcholinergic receptors in the brain using radiolabeled pyridyl-7-azabicyclo 2.2.1!heptanes
GB9706222D0 (en) * 1997-03-26 1997-05-14 Zeneca Ltd Bicyclic amine derivatives

Also Published As

Publication number Publication date
WO1999038866A1 (en) 1999-08-05
AU2609999A (en) 1999-08-16
EP1068204A1 (en) 2001-01-17
WO1999038866A8 (en) 1999-10-28
JP2002501921A (en) 2002-01-22

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