ZA991745B - Combination of a selective NMDA NR2B antagonist and an opioid analgesic. - Google Patents
Combination of a selective NMDA NR2B antagonist and an opioid analgesic.Info
- Publication number
- ZA991745B ZA991745B ZA9901745A ZA991745A ZA991745B ZA 991745 B ZA991745 B ZA 991745B ZA 9901745 A ZA9901745 A ZA 9901745A ZA 991745 A ZA991745 A ZA 991745A ZA 991745 B ZA991745 B ZA 991745B
- Authority
- ZA
- South Africa
- Prior art keywords
- combination
- opioid analgesic
- selective nmda
- nr2b antagonist
- nmda nr2b
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9804885.3A GB9804885D0 (en) | 1998-03-06 | 1998-03-06 | Therapeutic combination |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA991745B true ZA991745B (en) | 1999-09-06 |
Family
ID=10828172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9901745A ZA991745B (en) | 1998-03-06 | 1999-03-04 | Combination of a selective NMDA NR2B antagonist and an opioid analgesic. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6538008B1 (xx) |
EP (1) | EP1059923A1 (xx) |
JP (1) | JP2002505287A (xx) |
AU (1) | AU3260099A (xx) |
CA (1) | CA2321685A1 (xx) |
GB (1) | GB9804885D0 (xx) |
WO (1) | WO1999044610A1 (xx) |
ZA (1) | ZA991745B (xx) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5900420A (en) * | 1997-06-19 | 1999-05-04 | Cole; William L. | Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine |
CA2370030C (en) | 1999-04-09 | 2007-08-14 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
WO2001052851A1 (en) * | 2000-01-22 | 2001-07-26 | Albert Shulman | Methods for the treatment of substance abuse |
EP1186303A3 (en) * | 2000-09-06 | 2003-12-10 | Pfizer Products Inc. | Pharmaceutical combinations, for the treatment of stroke and traumatic brain injury, containing a neutrophil inhibiting factor and an selective NMDA-NR2B receptor antagonist |
IL145584A0 (en) | 2000-10-02 | 2002-06-30 | Pfizer Prod Inc | Nmda nr2b antagonists for treatment |
ZA200108038B (en) * | 2000-10-02 | 2003-04-01 | Pfizer Prod Inc | Prophylactic use of n-methyl-d-asparrate (NMDA) antagonists. |
EP1674087A1 (en) * | 2000-10-02 | 2006-06-28 | Pfizer Products Inc. | Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists |
US20040204341A1 (en) * | 2001-06-12 | 2004-10-14 | Christopher Allen | Nr2b receptor antagonists for the treatment or prevention of migraines |
US8084447B2 (en) | 2001-09-03 | 2011-12-27 | Newron Pharmaceuticals S.P.A. | Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use |
AU2003234395B2 (en) * | 2002-05-13 | 2008-01-24 | Endo Pharmaceuticals Inc. | Abuse-resistant opioid solid dosage form |
JP2006500395A (ja) * | 2002-09-09 | 2006-01-05 | エンド ファーマシューティカルズ インコーポレーテッド | 組み合わされた即時放出及び徐放の鎮痛組成物 |
US6864271B2 (en) * | 2002-11-12 | 2005-03-08 | The Foundation For The Lsu Health Sciences Center | Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives |
WO2005041963A1 (en) * | 2003-10-21 | 2005-05-12 | Arakis Ltd. | The use of non-opiates for the potentation of opiates |
BRPI0415643A (pt) * | 2003-10-21 | 2006-12-12 | Arakis Ltd | uso de ifenprodil no tratamento de dor |
AU2005224160A1 (en) * | 2004-03-17 | 2005-09-29 | Sosei R&D Ltd. | The treatment of inflammatory disorders and pain using beta-aminoalcohols |
KR20070007850A (ko) * | 2004-04-29 | 2007-01-16 | 콜드웰 갤러, 인코포레이티드 | 국소용 메타돈 조성물 및 그의 사용 방법 |
CN106176584A (zh) * | 2005-10-14 | 2016-12-07 | 詹森药业有限公司 | 用于静脉施用的替比法尼制剂 |
HUP0600809A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600810A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600808A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New benzamide derivatives as bradykinin antagonists, process for their preparation and pharmaceutical compositions containing them |
AU2007360523A1 (en) * | 2007-10-27 | 2009-04-30 | Richter Gedeon Nyrt. | New non-peptide derivatives as bradykinin B1 antagonists |
KR20110038139A (ko) | 2008-07-17 | 2011-04-13 | 메리얼 리미티드 | 폴리오르소에스테르 및 이의 제형의 안정성 강화 방법 |
US20110190347A1 (en) * | 2008-08-21 | 2011-08-04 | Richter Gedeon Nyrt. | Methods for treating neuropathic pain |
WO2010022304A1 (en) * | 2008-08-21 | 2010-02-25 | Forest Laboratories Holdings Limited | Methods for treating cns disorders |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR5733M (xx) | 1966-09-27 | 1968-01-22 | ||
FR2534580A1 (fr) | 1982-10-13 | 1984-04-20 | Synthelabo | Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent |
FR2628740B3 (fr) | 1989-04-12 | 1990-01-19 | Synthelabo | Procede de preparation des enantiomeres du (chloro-4 phenyl)-1 (((fluoro-4 phenyl)methyl)-4 piperidyl-1)-2 ethanol |
TW281670B (xx) | 1993-09-02 | 1996-07-21 | Hoffmann La Roche | |
US5489717A (en) * | 1994-07-08 | 1996-02-06 | Warner-Lambert Company | Glutamate (NMDA) receptor antagonists |
GB9520444D0 (en) | 1995-10-06 | 1995-12-06 | Pharmacia Spa | Disubstituted piperidine derivatives |
TW450807B (en) | 1995-09-15 | 2001-08-21 | Pfizer | Pharmaceutical compositions for treating tinnitus comprising neuroprotective agents |
AUPN605795A0 (en) * | 1995-10-19 | 1995-11-09 | F.H. Faulding & Co. Limited | Analgesic pharmaceutical composition |
ZA9610738B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
-
1998
- 1998-03-06 GB GBGB9804885.3A patent/GB9804885D0/en not_active Ceased
-
1999
- 1999-02-26 WO PCT/GB1999/000585 patent/WO1999044610A1/en not_active Application Discontinuation
- 1999-02-26 EP EP99937872A patent/EP1059923A1/en not_active Withdrawn
- 1999-02-26 US US09/622,733 patent/US6538008B1/en not_active Expired - Fee Related
- 1999-02-26 JP JP2000534212A patent/JP2002505287A/ja not_active Withdrawn
- 1999-02-26 AU AU32600/99A patent/AU3260099A/en not_active Abandoned
- 1999-02-26 CA CA002321685A patent/CA2321685A1/en not_active Abandoned
- 1999-03-04 ZA ZA9901745A patent/ZA991745B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
GB9804885D0 (en) | 1998-04-29 |
JP2002505287A (ja) | 2002-02-19 |
US6538008B1 (en) | 2003-03-25 |
AU3260099A (en) | 1999-09-20 |
CA2321685A1 (en) | 1999-09-10 |
EP1059923A1 (en) | 2000-12-20 |
WO1999044610A1 (en) | 1999-09-10 |
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