ZA989313B - Novel compounds for treating diseases associated with the biological effect of endothelin. - Google Patents

Novel compounds for treating diseases associated with the biological effect of endothelin.

Info

Publication number
ZA989313B
ZA989313B ZA9809313A ZA989313A ZA989313B ZA 989313 B ZA989313 B ZA 989313B ZA 9809313 A ZA9809313 A ZA 9809313A ZA 989313 A ZA989313 A ZA 989313A ZA 989313 B ZA989313 B ZA 989313B
Authority
ZA
South Africa
Prior art keywords
endothelin
novel compounds
diseases associated
treating diseases
biological effect
Prior art date
Application number
ZA9809313A
Inventor
Michael Puhl
Wilhelm Amberg
Heinz Hillen
Andreas Kling
Stefan Hergenroeder
Claus Otto Markert
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA989313B publication Critical patent/ZA989313B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA9809313A 1997-10-14 1998-10-13 Novel compounds for treating diseases associated with the biological effect of endothelin. ZA989313B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19745151A DE19745151A1 (en) 1997-10-14 1997-10-14 New N-2-Mercapto-3-phenyl-propionyl di:peptide derivatives

Publications (1)

Publication Number Publication Date
ZA989313B true ZA989313B (en) 2000-04-13

Family

ID=7845384

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9809313A ZA989313B (en) 1997-10-14 1998-10-13 Novel compounds for treating diseases associated with the biological effect of endothelin.

Country Status (6)

Country Link
EP (1) EP1023318A1 (en)
JP (1) JP2001519440A (en)
AU (1) AU9626498A (en)
DE (1) DE19745151A1 (en)
WO (1) WO1999019346A1 (en)
ZA (1) ZA989313B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777443B2 (en) * 2001-05-15 2004-08-17 Novartis Ag Dipeptide derivatives
WO2003006041A1 (en) * 2001-07-12 2003-01-23 Takeda Chemical Industries, Ltd. Preventives/remedies for malignant tumor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2100171A1 (en) * 1991-01-31 1992-08-01 Kazumi Shiosaki Endothelin converting enzyme inhibitors
FR2679564A1 (en) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med NOVEL ACYLMERCAPTOALCANOLDIPEPTIDES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
AU3494093A (en) * 1993-01-22 1994-08-15 Institut National De La Sante Et De La Recherche Medicale (Inserm) S-lipophilic aliphatic carbonyl {n-mercaptoacyl-(amino acid or peptide)} compounds as antihypertensive agents
FR2745570B1 (en) * 1996-03-04 1998-06-19 Roussel Uclaf NOVEL SULFUR DERIVATIVES COMPRISING A RETROAMIDE BINDING, THEIR PREPARATION METHOD AND INTERMEDIATES, THEIR APPLICATION AS MEDICAMENTS, AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
AU9626498A (en) 1999-05-03
JP2001519440A (en) 2001-10-23
EP1023318A1 (en) 2000-08-02
WO1999019346A1 (en) 1999-04-22
DE19745151A1 (en) 1999-04-15

Similar Documents

Publication Publication Date Title
ATA227794A (en) FITTING FOR ADJUSTING THE DRAWERS
ZA200007642B (en) Treatment of airborne microorganisms.
GB9417831D0 (en) Biological manipulation
LT2000039A (en) Biocontrol agents for control of root diseases
EP0749274A4 (en) Fungicidal toxins from biocontrol bacteria
EP0999848A4 (en) Chimeric proteins for the treatment of diabetes
ZA9810027B (en) Treatment of organic materials.
GB9807520D0 (en) Modified biological material
GB9405951D0 (en) Biological control agents
ZA989313B (en) Novel compounds for treating diseases associated with the biological effect of endothelin.
ZA982255B (en) Process for the preparation of arylmalonates.
ZA969315B (en) Processes and intermediates for the preparation of ziprasidone.
GB9811859D0 (en) Biological manipulation
ZA9811598B (en) A substance or composition for the treatment of cancer.
ZA975705B (en) The treatment of plant diseases.
ZA9711116B (en) The treatment of materials.
PL318423A1 (en) Biological treatment plant
PL106862U1 (en) Biological treatment plant
IT1268843B1 (en) PERCOLATOR FOR THE BIOLOGICAL OXIDATIVE TREATMENT OF LIQUAMS
GB9707417D0 (en) Biological compounds
EG19797A (en) Biological insecticide
GB9526230D0 (en) Biological compounds
GB9521497D0 (en) Biological compounds
GB9521498D0 (en) Biological compounds
GB9518023D0 (en) Biological compounds