ZA985324B - 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyloxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxyphenylsilyl)methyloxy]phenol - Google Patents

2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyloxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxyphenylsilyl)methyloxy]phenol

Info

Publication number
ZA985324B
ZA985324B ZA985324A ZA985324A ZA985324B ZA 985324 B ZA985324 B ZA 985324B ZA 985324 A ZA985324 A ZA 985324A ZA 985324 A ZA985324 A ZA 985324A ZA 985324 B ZA985324 B ZA 985324B
Authority
ZA
South Africa
Prior art keywords
methoxyphenylsilyl
methyloxy
phenol
dimethyl
butyl
Prior art date
Application number
ZA985324A
Other languages
English (en)
Inventor
Michael L Edwards
Roger A Parker
Mark J Vaal
Kim S Chen
James E Matt Jr
Mark T Yates
Original Assignee
Hoechst Marion Roussell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussell Inc filed Critical Hoechst Marion Roussell Inc
Publication of ZA985324B publication Critical patent/ZA985324B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA985324A 1997-06-25 1998-06-18 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyloxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxyphenylsilyl)methyloxy]phenol ZA985324B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88184397A 1997-06-25 1997-06-25

Publications (1)

Publication Number Publication Date
ZA985324B true ZA985324B (en) 1999-01-07

Family

ID=25379324

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA985324A ZA985324B (en) 1997-06-25 1998-06-18 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyloxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxyphenylsilyl)methyloxy]phenol

Country Status (7)

Country Link
EP (1) EP0996623A1 (es)
JP (1) JP2002506443A (es)
AR (1) AR013115A1 (es)
AU (1) AU7588498A (es)
CA (1) CA2295232A1 (es)
WO (1) WO1998058937A1 (es)
ZA (1) ZA985324B (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5155250A (en) * 1990-07-05 1992-10-13 Merrell Dow Pharmaceuticals Inc. 2,6-di-alkyl-4-silyl-phenols as antiatheroscerotic agents
EP1468693A3 (en) * 1993-12-10 2004-11-03 Merrell Pharmaceuticals Inc. Use of 2,6-di -alkyl-4-silyl-phenols for treating diabetes mellitus
US5677291A (en) * 1993-12-10 1997-10-14 Hoechst Marion Roussel, Inc. Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols
US5608095A (en) * 1996-04-30 1997-03-04 Hoechst Marion Roussel, Inc. Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents
IL126744A0 (en) * 1996-04-30 1999-08-17 Hoechst Marion Roussel Inc Method of inhibiting vascular cell adhesion molecule-1 and treating chronic inflammatory diseases with 2,6-Di-alkyl-4-silyl-phenols

Also Published As

Publication number Publication date
AR013115A1 (es) 2000-12-13
JP2002506443A (ja) 2002-02-26
AU7588498A (en) 1999-01-04
CA2295232A1 (en) 1998-12-30
WO1998058937A1 (en) 1998-12-30
EP0996623A1 (en) 2000-05-03

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