ZA97327B - Substituted histidine inhibitors of protein farnesyltransferase - Google Patents

Substituted histidine inhibitors of protein farnesyltransferase

Info

Publication number
ZA97327B
ZA97327B ZA97327A ZA97327A ZA97327B ZA 97327 B ZA97327 B ZA 97327B ZA 97327 A ZA97327 A ZA 97327A ZA 97327 A ZA97327 A ZA 97327A ZA 97327 B ZA97327 B ZA 97327B
Authority
ZA
South Africa
Prior art keywords
inhibitors
protein farnesyltransferase
substituted histidine
histidine
substituted
Prior art date
Application number
ZA97327A
Inventor
Annette Marian Doherty
James Stanley Kaltenbronn
Daniele Leonard
John Quin Iii
Jeffrey David Scholten
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA97327B publication Critical patent/ZA97327B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA97327A 1996-01-16 1997-01-15 Substituted histidine inhibitors of protein farnesyltransferase ZA97327B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US995696P 1996-01-16 1996-01-16

Publications (1)

Publication Number Publication Date
ZA97327B true ZA97327B (en) 1997-07-22

Family

ID=21740700

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA97327A ZA97327B (en) 1996-01-16 1997-01-15 Substituted histidine inhibitors of protein farnesyltransferase

Country Status (4)

Country Link
US (1) US6008372A (en)
AU (1) AU1529997A (en)
WO (1) WO1997026246A1 (en)
ZA (1) ZA97327B (en)

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US5571792A (en) * 1994-06-30 1996-11-05 Warner-Lambert Company Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase

Also Published As

Publication number Publication date
US6008372A (en) 1999-12-28
AU1529997A (en) 1997-08-11
WO1997026246A1 (en) 1997-07-24

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