ZA955079B - Aryl alkyl alkenyl and alkynylmacrolides having immuno-suppressive activity - Google Patents

Aryl alkyl alkenyl and alkynylmacrolides having immuno-suppressive activity

Info

Publication number
ZA955079B
ZA955079B ZA955079A ZA955079A ZA955079B ZA 955079 B ZA955079 B ZA 955079B ZA 955079 A ZA955079 A ZA 955079A ZA 955079 A ZA955079 A ZA 955079A ZA 955079 B ZA955079 B ZA 955079B
Authority
ZA
South Africa
Prior art keywords
alkynylmacrolides
immuno
aryl alkyl
suppressive activity
alkyl alkenyl
Prior art date
Application number
ZA955079A
Other languages
English (en)
Inventor
Kathleen M Rupprecht
Robert K Baker
Hyun O Ok
William H Parsons
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA955079B publication Critical patent/ZA955079B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA955079A 1994-06-21 1995-06-20 Aryl alkyl alkenyl and alkynylmacrolides having immuno-suppressive activity ZA955079B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/263,298 US5550233A (en) 1994-06-21 1994-06-21 Aryl, alkyl, alkenyl and alkynylmacrolides having immunosuppressive activity

Publications (1)

Publication Number Publication Date
ZA955079B true ZA955079B (en) 1996-01-31

Family

ID=23001185

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA955079A ZA955079B (en) 1994-06-21 1995-06-20 Aryl alkyl alkenyl and alkynylmacrolides having immuno-suppressive activity

Country Status (6)

Country Link
US (1) US5550233A (xx)
EP (1) EP0767791A1 (xx)
AU (1) AU2862895A (xx)
IL (1) IL114101A0 (xx)
WO (1) WO1995035299A1 (xx)
ZA (1) ZA955079B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
DE10250870A1 (de) * 2002-10-31 2004-05-13 Switch Biotech Ag Zusammensetzung enthaltend Aktivatoren von IK-Kaliumkanälen und Calcineurin-Antagonisten und deren Verwendung
CA2571710A1 (en) 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
US8445002B2 (en) 2009-05-06 2013-05-21 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0427680T3 (da) * 1989-11-09 1995-12-18 Sandoz Ltd Heteroatom-holdige cykliske forbindelser
IE904050A1 (en) * 1989-11-13 1991-05-22 Merck & Co Inc Aminomacrolides and derivatives having immunosuppressive¹activity
EP0455427A1 (en) * 1990-04-30 1991-11-06 Merck & Co. Inc. Deoxymacrolide derivatives having immunosuppressive activity
GB2244991A (en) * 1990-06-11 1991-12-18 Fujisawa Pharmaceutical Co Tricyclo compounds
GB2245891A (en) * 1990-07-09 1992-01-15 Fujisawa Pharmaceutical Co Tricyclo compounds
EP0480623A1 (en) * 1990-10-11 1992-04-15 Merck & Co. Inc. New halomacrolides and derivatives having immunosuppressive activity
WO1992020688A1 (en) * 1991-05-13 1992-11-26 Merck & Co., Inc. Amino o-aryl, o-alkyl, o-alkenyl and o-alkynyl macrolides
US5189042A (en) * 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity

Also Published As

Publication number Publication date
EP0767791A1 (en) 1997-04-16
IL114101A0 (en) 1995-10-31
AU2862895A (en) 1996-01-15
US5550233A (en) 1996-08-27
WO1995035299A1 (en) 1995-12-28

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