ZA928894B - Chemical compounds-phenol derivatives as agonists of a cyclic AMP dependent protein kinase - Google Patents

Chemical compounds-phenol derivatives as agonists of a cyclic AMP dependent protein kinase

Info

Publication number
ZA928894B
ZA928894B ZA928894A ZA928894A ZA928894B ZA 928894 B ZA928894 B ZA 928894B ZA 928894 A ZA928894 A ZA 928894A ZA 928894 A ZA928894 A ZA 928894A ZA 928894 B ZA928894 B ZA 928894B
Authority
ZA
South Africa
Prior art keywords
agonists
protein kinase
chemical compounds
dependent protein
cyclic amp
Prior art date
Application number
ZA928894A
Other languages
English (en)
Inventor
Kenneth John Murray
Roderick Alan Porter
Hunter Douglas Prain
Brian Herbert Warrington
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA928894B publication Critical patent/ZA928894B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4021—Esters of aromatic acids (P-C aromatic linkage)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA928894A 1991-11-20 1992-11-18 Chemical compounds-phenol derivatives as agonists of a cyclic AMP dependent protein kinase ZA928894B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919124579A GB9124579D0 (en) 1991-11-20 1991-11-20 Chemical compounds

Publications (1)

Publication Number Publication Date
ZA928894B true ZA928894B (en) 1994-05-18

Family

ID=10704882

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA928894A ZA928894B (en) 1991-11-20 1992-11-18 Chemical compounds-phenol derivatives as agonists of a cyclic AMP dependent protein kinase

Country Status (11)

Country Link
EP (1) EP0620815A1 (xx)
JP (1) JPH07503235A (xx)
AU (1) AU2927492A (xx)
CA (1) CA2124003A1 (xx)
GB (1) GB9124579D0 (xx)
MX (1) MX9206709A (xx)
NZ (1) NZ245168A (xx)
PT (1) PT101073A (xx)
TW (1) TW221812B (xx)
WO (1) WO1993010107A1 (xx)
ZA (1) ZA928894B (xx)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3590082A (en) * 1967-10-06 1971-06-29 Merck & Co Inc 4-(p-fluorophenyl)salicylamide derivatives
JPH05509296A (ja) * 1990-05-21 1993-12-22 スミス・クライン・アンド・フレンチ・ラボラトリース・リミテッド 医薬用のフェノールおよびピリジノール誘導体

Also Published As

Publication number Publication date
GB9124579D0 (en) 1992-01-08
EP0620815A1 (en) 1994-10-26
PT101073A (pt) 1994-02-28
JPH07503235A (ja) 1995-04-06
CA2124003A1 (en) 1993-05-27
AU2927492A (en) 1993-06-15
NZ245168A (en) 1995-06-27
WO1993010107A1 (en) 1993-05-27
TW221812B (xx) 1994-03-21
MX9206709A (es) 1993-05-01

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