ZA914959B - Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids - Google Patents

Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids

Info

Publication number
ZA914959B
ZA914959B ZA914959A ZA914959A ZA914959B ZA 914959 B ZA914959 B ZA 914959B ZA 914959 A ZA914959 A ZA 914959A ZA 914959 A ZA914959 A ZA 914959A ZA 914959 B ZA914959 B ZA 914959B
Authority
ZA
South Africa
Prior art keywords
propionic acids
quinolinyl
substituted
thioalkanoic acid
substituted phenyl
Prior art date
Application number
ZA914959A
Other languages
English (en)
Inventor
Russell Donovan Cousins
Donovan Cousins Russell
John Gerald Gleason
Gerald Gleason John
James Simpson Frazee
Simpson Frazee James
Ralph Floyd Hall
Floyd Hall Ralph
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA914959B publication Critical patent/ZA914959B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA914959A 1990-06-28 1991-06-27 Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids ZA914959B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/545,258 US4996214A (en) 1990-06-28 1990-06-28 Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids and leucotriene antagonist use thereof

Publications (1)

Publication Number Publication Date
ZA914959B true ZA914959B (en) 1992-06-24

Family

ID=24175503

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914959A ZA914959B (en) 1990-06-28 1991-06-27 Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids

Country Status (9)

Country Link
US (1) US4996214A (xx)
EP (1) EP0536310A1 (xx)
JP (1) JPH05508411A (xx)
KR (1) KR930701408A (xx)
AU (1) AU8238891A (xx)
CA (1) CA2083710A1 (xx)
PT (1) PT98078A (xx)
WO (1) WO1992000279A1 (xx)
ZA (1) ZA914959B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018889A1 (en) * 1990-06-06 1991-12-12 Smithkline Beecham Corporation Leukotriene antagonists
WO1992016104A1 (en) * 1991-03-13 1992-10-01 Smithkline Beecham Corporation Leukotriene antagonists
WO1999047497A2 (en) * 1998-03-13 1999-09-23 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
US6242493B1 (en) 1998-03-13 2001-06-05 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
US20050203081A1 (en) * 2004-02-25 2005-09-15 Jinbo Lee Inhibitors of protein tyrosine phosphatase 1B
WO2005081954A2 (en) * 2004-02-25 2005-09-09 Wyeth Inhibitors of protein tyrosine phosphatase 1b

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191508B (en) * 1982-12-02 1987-02-27 Alkaloida Vegyeszeti Gyar,Hu Process for preparing new chloromethyl-quinoline derivatives
NZ213986A (en) * 1984-10-30 1989-07-27 Usv Pharma Corp Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such
US4876346A (en) * 1985-05-02 1989-10-24 American Home Products Corporation Quinoline compounds
IE59889B1 (en) * 1986-02-14 1994-04-20 Merck Frosst Canada Inc 2-substituted quinoline dioic acids
GB8711802D0 (en) * 1987-05-19 1987-06-24 Fujisawa Pharmaceutical Co Dithioacetal compounds
DE3814504A1 (de) * 1988-04-29 1989-11-09 Bayer Ag (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
AU8238891A (en) 1992-01-23
EP0536310A4 (en) 1993-02-05
PT98078A (pt) 1993-06-30
CA2083710A1 (en) 1991-12-29
JPH05508411A (ja) 1993-11-25
EP0536310A1 (en) 1993-04-14
KR930701408A (ko) 1993-06-11
WO1992000279A1 (en) 1992-01-09
US4996214A (en) 1991-02-26

Similar Documents

Publication Publication Date Title
HU9301710D0 (en) Copoliamides of terephthalic acid
EG18144A (en) Heterocyclic oxphtalazinyl acetic acids
GB9027975D0 (en) Peroxycarboxylic acid
AP9200447A0 (en) Acetic acid derivatives
GB8811645D0 (en) Novel 2-(5-fluoronicotinoyl)acetic acid derivative/salts thereof
ZA932790B (en) Acetic acid derivatives
EP0464381A3 (en) 2-methoxyiminocarboxylic acid esters
ZA911398B (en) Carboxylic acid derivatives
EP0252880A3 (en) Hydroxyphosphono carboxylic acids
ZA914959B (en) Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids
ZA913132B (en) Carboxylic acid derivatives
IL88729A0 (en) Heterocyclic oxophthalazinyl acetic acids
GB8630759D0 (en) Carboxylic acid derivatives
ZA868450B (en) Heterocyclic oxophtalazinyl acetic acids
AU1359888A (en) Light-sensitive aryl-diazide-sulphonic acids
GB8727048D0 (en) Acetic acid
AU561274B2 (en) Phenyl acetic acid amides
GB8700114D0 (en) Imidazol-1-yl-carboxylic acid ester derivatives
AU554739B2 (en) Azethidinyl acetic acids
EP0467840A3 (en) Derivatives of cyclopropyle acetic acid
GB8525881D0 (en) 4-(3-thienyl)phenylalkanoic acids
CS645090A3 (en) R-esters of (6-amino-2-benzothiazolylthio)acetic acid
HRP940504A2 (en) Cyclopropyle acetic acid derivatives
JPS57200344A (en) Propionic acid amide derivative
GB2235454B (en) Propanoic acid derivatives