ZA899503B - Novel fluorine-containing 2-nitroimidazole derivatives and radiosensitizer comprising the same - Google Patents
Novel fluorine-containing 2-nitroimidazole derivatives and radiosensitizer comprising the sameInfo
- Publication number
- ZA899503B ZA899503B ZA899503A ZA899503A ZA899503B ZA 899503 B ZA899503 B ZA 899503B ZA 899503 A ZA899503 A ZA 899503A ZA 899503 A ZA899503 A ZA 899503A ZA 899503 B ZA899503 B ZA 899503B
- Authority
- ZA
- South Africa
- Prior art keywords
- radiosensitizer
- same
- novel fluorine
- nitroimidazole derivatives
- nitroimidazole
- Prior art date
Links
- 150000004959 2-nitroimidazoles Chemical class 0.000 title 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 title 1
- 229910052731 fluorine Inorganic materials 0.000 title 1
- 239000011737 fluorine Substances 0.000 title 1
- 239000002534 radiation-sensitizing agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP31597488 | 1988-12-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA899503B true ZA899503B (en) | 1990-09-26 |
Family
ID=18071820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA899503A ZA899503B (en) | 1988-12-14 | 1989-12-13 | Novel fluorine-containing 2-nitroimidazole derivatives and radiosensitizer comprising the same |
Country Status (7)
Country | Link |
---|---|
US (1) | US4977273A (ko) |
EP (1) | EP0373630A1 (ko) |
KR (1) | KR900009606A (ko) |
AU (1) | AU625581B2 (ko) |
CA (1) | CA2005261A1 (ko) |
IL (1) | IL92597A0 (ko) |
ZA (1) | ZA899503B (ko) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5304654A (en) * | 1987-06-10 | 1994-04-19 | Yasunori Nishijima | Fluorine-containing nitroimidazole compounds |
US6855828B1 (en) | 1992-11-19 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Detection of hypoxia |
US6252087B1 (en) | 1992-11-19 | 2001-06-26 | The Trustees Of The University Of Pennsylvania | Nitroaromatic compounds for the detection of hypoxia |
JP4169782B2 (ja) * | 1992-11-19 | 2008-10-22 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 低酸素症の検出 |
US5721265A (en) * | 1994-08-05 | 1998-02-24 | Sri International | Fluorinated 2-nitroimidazole analogs for detecting hypoxic tumor cells |
US6060604A (en) * | 1995-03-31 | 2000-05-09 | Florida State University | Pharmaceutical compounds comprising polyamines substituted with electron-affinic groups |
US5965621A (en) * | 1995-08-17 | 1999-10-12 | Allergan | Methods and compositions for reducing or maintaining body weight in a mammal |
US20050026974A1 (en) * | 1996-02-08 | 2005-02-03 | Trustees Of The University Of Pennsylvania | Detection of hypoxia |
US6331286B1 (en) | 1998-12-21 | 2001-12-18 | Photogen, Inc. | Methods for high energy phototherapeutics |
US8974363B2 (en) | 1997-12-11 | 2015-03-10 | Provectus Pharmatech, Inc. | Topical medicaments and methods for photodynamic treatment of disease |
US8557298B2 (en) | 1998-08-06 | 2013-10-15 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
US7384623B1 (en) | 1998-12-21 | 2008-06-10 | Provectus Pharmatech, Inc. | High energy phototherapeutic agents |
US20020001567A1 (en) * | 1998-12-21 | 2002-01-03 | Photogen, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
US8470296B2 (en) * | 1998-12-21 | 2013-06-25 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
US7875602B2 (en) * | 2005-10-21 | 2011-01-25 | Sutter West Bay Hospitals | Camptothecin derivatives as chemoradiosensitizing agents |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1329206C (en) * | 1987-06-10 | 1994-05-03 | Tsutomu Kagiya | Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same |
-
1989
- 1989-12-07 IL IL92597A patent/IL92597A0/xx unknown
- 1989-12-12 CA CA002005261A patent/CA2005261A1/en not_active Abandoned
- 1989-12-12 US US07/448,909 patent/US4977273A/en not_active Expired - Fee Related
- 1989-12-13 AU AU46713/89A patent/AU625581B2/en not_active Ceased
- 1989-12-13 KR KR1019890018481A patent/KR900009606A/ko not_active Application Discontinuation
- 1989-12-13 ZA ZA899503A patent/ZA899503B/xx unknown
- 1989-12-13 EP EP89123062A patent/EP0373630A1/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU625581B2 (en) | 1992-07-16 |
IL92597A0 (en) | 1990-08-31 |
CA2005261A1 (en) | 1990-06-14 |
US4977273A (en) | 1990-12-11 |
KR900009606A (ko) | 1990-07-05 |
AU4671389A (en) | 1990-06-21 |
EP0373630A1 (en) | 1990-06-20 |
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