ZA892058B - Mesotetraphenylporphyrin complex compounds,process for their production and pharmaceutical agents containing them - Google Patents

Mesotetraphenylporphyrin complex compounds,process for their production and pharmaceutical agents containing them

Info

Publication number
ZA892058B
ZA892058B ZA892058A ZA892058A ZA892058B ZA 892058 B ZA892058 B ZA 892058B ZA 892058 A ZA892058 A ZA 892058A ZA 892058 A ZA892058 A ZA 892058A ZA 892058 B ZA892058 B ZA 892058B
Authority
ZA
South Africa
Prior art keywords
complex compounds
mesotetraphenylporphyrin
production
pharmaceutical agents
agents containing
Prior art date
Application number
ZA892058A
Inventor
Ulrich Niedballa
Niedballa Ulrich
Hanns-Joachim Winmann
Winmann Hanns-Joachim
Heinz Gries
Gries Heinz
Jurgen Conrad
Conrad Jurgen
Sabina Hofmann
Hofmann Sabina
Ulrich Speck
Speck Ulrich
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA892058B publication Critical patent/ZA892058B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Porphyrin complex compounds, consisting of a meso-tetraphenyl- porphyrin ligand, if appropriate at least one ion of an element of atomic number 13, 21, 32, 37-39, 42-44, 49, 50 or 57-83 and, if appropriate, cations of inorganic and/or organic bases, amino acids or amino acid amides, are useful diagnostics and therapeutics.
ZA892058A 1988-03-18 1989-03-17 Mesotetraphenylporphyrin complex compounds,process for their production and pharmaceutical agents containing them ZA892058B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3809671A DE3809671A1 (en) 1988-03-18 1988-03-18 PORPHYRINE COMPLEX COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THEM

Publications (1)

Publication Number Publication Date
ZA892058B true ZA892058B (en) 1989-11-29

Family

ID=6350409

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892058A ZA892058B (en) 1988-03-18 1989-03-17 Mesotetraphenylporphyrin complex compounds,process for their production and pharmaceutical agents containing them

Country Status (13)

Country Link
EP (1) EP0336879B1 (en)
JP (1) JPH01275583A (en)
AT (1) ATE148121T1 (en)
AU (1) AU627451B2 (en)
DE (2) DE3809671A1 (en)
DK (1) DK132889A (en)
ES (1) ES2099697T3 (en)
GR (1) GR3022868T3 (en)
IL (1) IL89657A0 (en)
NO (1) NO891187L (en)
NZ (1) NZ228405A (en)
PT (1) PT90033B (en)
ZA (1) ZA892058B (en)

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JP2815615B2 (en) * 1988-06-07 1998-10-27 日本メジフィジックス株式会社 Diethylenetriaminepentaacetic acid derivatives and their uses
EP0529002B1 (en) * 1990-05-15 2001-10-04 Hyperion, Inc. Fluorescent porphyrin, and fluorescent phthalocyanine - polyethylene glycol, polyol, and saccharide derivatives as fluorescent probes
JPH05507518A (en) * 1990-05-15 1993-10-28 ダイアトロン・コーポレイション Phthalocyanatopolyethylene glycols and phthalocyanatosaccharides for fluorescent digoxin reagents
US5919922A (en) * 1990-05-15 1999-07-06 Hyperion, Inc. Fluorescent dyes free of aggregation and serum binding
US6060598A (en) * 1990-05-15 2000-05-09 Hyperion, Inc. Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding
US5880287A (en) * 1990-05-15 1999-03-09 Hyperion, Inc. Polyoxyhydrocarbyl related products and methods for fluorescence assays
ATE115864T1 (en) * 1990-05-30 1995-01-15 Deutsches Krebsforsch POLYETHER-SUBSTITUTED TUMOR AGENTS.
DE4017439C2 (en) * 1990-05-30 1994-06-23 Deutsches Krebsforsch Polyether-substituted tumor agents
US5236915A (en) * 1990-05-31 1993-08-17 Health Research, Inc. Meso poly(4-sulfonatophenyl) porphines as MRI image enhancing agents
US5262532A (en) * 1991-07-22 1993-11-16 E.R. Squibb & Sons, Inc. Paramagnetic metalloporphyrins as contrast agents for magnetic resonance imaging
US6875864B2 (en) 1991-08-01 2005-04-05 Bracco International B.V. Aminocarboxylate ligands having substituted aromatic amide moieties
US6362175B1 (en) * 1991-09-20 2002-03-26 The Trustees Of The University Of Pennsylvania Porphyrin compounds for imaging tissue oxygen
EP0673655A1 (en) * 1992-03-19 1995-09-27 Daikin Industries, Limited Mri contrast medium and diagnostic method
GB9301898D0 (en) * 1993-01-30 1993-03-17 Univ Liverpool Method for localising and measuring the profileration of cancer and compositions for same
DE4303969B4 (en) * 1993-02-10 2006-01-19 Oped Gmbh Shoe, especially ski boot
DE4305523A1 (en) * 1993-02-17 1994-08-18 Diagnostikforschung Inst Meso-tetraphenylporphyrin complexes, processes for their preparation and pharmaceutical compositions containing them
US6127356A (en) * 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
WO1995027705A1 (en) * 1994-04-08 1995-10-19 Bracco International B.V. Aromatic amide compounds and metal chelates thereof
EP0758907A1 (en) * 1994-05-11 1997-02-26 Schering Aktiengesellschaft The use of porphyrin-complex or expanded porphyrin-complex compounds as localization diagnosticum for infarction or necrosis
WO1996009053A1 (en) * 1994-09-20 1996-03-28 Duke University Oxidoreductase activity of manganic porphyrins
EP0831891B1 (en) * 1995-06-07 2005-10-19 Duke University Oxidant scavengers
AU737650B2 (en) 1997-11-03 2001-08-23 Duke University Substituted porphyrins
DE19845782C1 (en) * 1998-09-22 2000-04-13 Schering Ag Process for the preparation of metal porphyrin-metal complex conjugates
US6194566B1 (en) 1997-12-02 2001-02-27 Schering Aktiengesellschaft Process for the production of metalloporphyrin-metal complex conjugates
DE69928655T2 (en) 1998-04-24 2006-08-24 Duke University SUBSTITUTED PORPHYRINE
ATE552260T1 (en) 1999-01-25 2012-04-15 Nat Jewish Health SUBSTITUTED PORPHYRINS AND THEIR THERAPEUTIC USE
US7097826B2 (en) * 1999-12-23 2006-08-29 Health Research, Inc. Chlorin and bacteriochlorin-based difunctional aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals
AU2002248366B2 (en) 2001-01-19 2006-10-26 Aeolus Sciences, Inc. Cancer therapy
AU2002312194B8 (en) 2001-06-01 2008-05-15 Aeolus Sciences, Inc. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
CA2488500A1 (en) 2002-06-07 2003-12-18 Duke University Substituted porphyrins
FR2867473B1 (en) * 2004-03-12 2006-06-23 Guerbet Sa PORPHYRINE COMPOUND AND HIGH FIELD USE IN MRI
FR2877943B1 (en) * 2004-11-16 2008-09-05 Univ De Coimbra NOVEL PORPHYRINE DERIVATIVES, IN PARTICULAR CHLORINES AND / OR BACTERIOCHLORIN, AND THEIR PHOTODYNAMIC THERAPY APPLICATIONS
US7663301B2 (en) * 2005-01-11 2010-02-16 General Electric Company Porphyrin compositions
RU2506083C2 (en) 2008-05-23 2014-02-10 Нэшнл Джуиш Хелт Method of treating disorders associated with alkylating agent exposure
WO2011034183A1 (en) * 2009-09-17 2011-03-24 国立大学法人九州大学 Porphyrin compound
CN101857597B (en) * 2010-05-27 2013-01-16 中国医学科学院生物医学工程研究所 Diethylene triamine pentaacetic acid or ethylene diamine tetraacetic acid or amine triacetic acid modified porphyrin, preparation method and application thereof
JP6693421B2 (en) * 2014-12-09 2020-05-13 ニプロ株式会社 Fluorine-substituted tetraphenylporphyrin derivative and its use
CN108264579B (en) * 2018-01-05 2020-05-05 云南师范大学 Hydrogel material containing macrocyclic rare earth complex, preparation method and application

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925767B2 (en) * 1981-06-10 1984-06-21 森六株式会社 Phospholipid liporem containing iron (2) porphyrin complex and oxygen adsorption/desorption agent
DE3129906C3 (en) * 1981-07-24 1996-12-19 Schering Ag Paramagnetic complex salts, their preparation and agents for use in NMR diagnostics
US4530794A (en) * 1982-12-01 1985-07-23 Taiho Pharmaceutical Co., Ltd. Iron-tetraphenylporphine complex having phosphocholine group
NL194579C (en) * 1983-01-21 2002-08-05 Schering Ag Diagnostic.
JPS60126291A (en) * 1983-03-14 1985-07-05 Koichi Shiyudo Porphyrin derivative
DE3464252D1 (en) * 1983-06-03 1987-07-23 Hoffmann La Roche Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation
FR2566776B1 (en) * 1984-06-27 1986-12-26 Univ Picardie PROCESS FOR THE PREPARATION OF METALLOPORPHYRINS
GB8429845D0 (en) * 1984-11-26 1985-01-03 Efamol Ltd Porphyrins & cancer treatment
DE3772785D1 (en) * 1986-01-23 1991-10-17 Squibb & Sons Inc 1-SUBSTITUTED-4,7,10-TRISCARBOXYMETHYL-1,4,7,10-TETRAAZACYCLODODECAN AND ANALOG.
AU617670B2 (en) * 1987-04-17 1991-12-05 David H. Dolphin Porphyrins, their syntheses and uses thereof

Also Published As

Publication number Publication date
NO891187L (en) 1989-09-19
EP0336879A1 (en) 1989-10-11
ES2099697T3 (en) 1997-06-01
PT90033B (en) 1994-05-31
IL89657A0 (en) 1989-09-28
DK132889A (en) 1989-09-19
DK132889D0 (en) 1989-03-17
AU627451B2 (en) 1992-08-27
PT90033A (en) 1989-11-10
DE3809671A1 (en) 1989-09-28
DE58909767D1 (en) 1997-03-06
NZ228405A (en) 1991-05-28
JPH01275583A (en) 1989-11-06
NO891187D0 (en) 1989-03-17
GR3022868T3 (en) 1997-06-30
AU3148589A (en) 1989-09-21
ATE148121T1 (en) 1997-02-15
EP0336879B1 (en) 1997-01-22

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