ZA876601B - Benzenesulphonamides useful as anti-arrhythmic agents - Google Patents

Benzenesulphonamides useful as anti-arrhythmic agents

Info

Publication number
ZA876601B
ZA876601B ZA876601A ZA876601A ZA876601B ZA 876601 B ZA876601 B ZA 876601B ZA 876601 A ZA876601 A ZA 876601A ZA 876601 A ZA876601 A ZA 876601A ZA 876601 B ZA876601 B ZA 876601B
Authority
ZA
South Africa
Prior art keywords
benzenesulphonamides
useful
arrhythmic agents
arrhythmic
agents
Prior art date
Application number
ZA876601A
Other languages
English (en)
Inventor
George Carroll Junior Buzby
Carroll Buzby Junior George
Thomas John Colatsky
John Colatsky Thomas
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA876601B publication Critical patent/ZA876601B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA876601A 1986-09-18 1987-09-03 Benzenesulphonamides useful as anti-arrhythmic agents ZA876601B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/909,133 US4721809A (en) 1986-09-18 1986-09-18 Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides

Publications (1)

Publication Number Publication Date
ZA876601B true ZA876601B (en) 1989-04-26

Family

ID=25426676

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876601A ZA876601B (en) 1986-09-18 1987-09-03 Benzenesulphonamides useful as anti-arrhythmic agents

Country Status (3)

Country Link
US (1) US4721809A (fi)
JP (1) JPS63139162A (fi)
ZA (1) ZA876601B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5144072A (en) * 1988-10-21 1992-09-01 American Home Products Corporation Anti-arrhythmic agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
WO1991018904A1 (en) * 1990-05-30 1991-12-12 American Home Products Corporation Substituted arylsulfonamides and benzamides
US5149700A (en) * 1990-05-30 1992-09-22 American Home Products Corporation Substituted arylsulfonamides and benzamides
US5187189A (en) * 1991-01-22 1993-02-16 American Home Products Corporation S-aminoalkyl-s-arylsulfoximines as antiarrhythmic agents
US5679706A (en) * 1994-09-30 1997-10-21 Bristol-Myers Squibb Company Combination of a potassium channel activator and an antiarrhythmic agent
SK542007A3 (sk) * 2007-04-20 2008-11-06 Unimed Pharma, Spol. S R. O. Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053204A (fi) *
US2233296A (en) * 1938-04-28 1941-02-25 Gen Aniline & Film Corp Process of making mono acyl alkylene diamines
US3580949A (en) * 1965-03-19 1971-05-25 Hoffmann La Roche N,n'-bis-(aminoalkyl)-benzyl-amines
NL6903832A (fi) * 1968-03-14 1969-09-16
US4564386A (en) * 1982-08-03 1986-01-14 Sumitomo Chemical Company, Limited Trifluoromethanesulfonanilides, and their production and use

Also Published As

Publication number Publication date
US4721809A (en) 1988-01-26
US4721809B1 (fi) 1989-06-06
JPS63139162A (ja) 1988-06-10

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