ZA86333B - Thromboxane antagonists - Google Patents

Thromboxane antagonists

Info

Publication number
ZA86333B
ZA86333B ZA86333A ZA86333A ZA86333B ZA 86333 B ZA86333 B ZA 86333B ZA 86333 A ZA86333 A ZA 86333A ZA 86333 A ZA86333 A ZA 86333A ZA 86333 B ZA86333 B ZA 86333B
Authority
ZA
South Africa
Prior art keywords
thromboxane antagonists
thromboxane
antagonists
Prior art date
Application number
ZA86333A
Other languages
English (en)
Inventor
Judith Senior
Kay Marie Troughton
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of ZA86333B publication Critical patent/ZA86333B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0091—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is bridged condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA86333A 1985-01-16 1986-01-16 Thromboxane antagonists ZA86333B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858501035A GB8501035D0 (en) 1985-01-16 1985-01-16 Prostaglandins

Publications (1)

Publication Number Publication Date
ZA86333B true ZA86333B (en) 1987-09-30

Family

ID=10572919

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA86333A ZA86333B (en) 1985-01-16 1986-01-16 Thromboxane antagonists

Country Status (11)

Country Link
US (1) US4902717A (fr)
EP (2) EP0336522A3 (fr)
JP (1) JPS62501500A (fr)
AU (1) AU594660B2 (fr)
CA (1) CA1269936A (fr)
DE (1) DE3671167D1 (fr)
DK (1) DK442186A (fr)
GB (2) GB8501035D0 (fr)
IE (1) IE860132L (fr)
WO (1) WO1986004234A2 (fr)
ZA (1) ZA86333B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ218881A (en) * 1986-01-16 1989-05-29 Nat Res Dev Prostaglandin derivatives and analogues as pharmaceuticals
GB2218311B (en) * 1986-01-16 1990-02-28 Nat Res Dev Prostagladin intermediates
US5077309A (en) * 1986-01-16 1991-12-31 National Research Development Corporation Prostaglandins
GB8600997D0 (en) * 1986-01-16 1986-02-19 Jones R L Prostaglandin synthesis
US5166201A (en) * 1990-11-30 1992-11-24 Merrell Dow Pharmaceuticals Inc. 2β,19-ethylene bridged steroids as aromatase inhibitors
WO2002098420A1 (fr) * 2001-06-01 2002-12-12 Cytovia, Inc. 4-substitute-1-(arylmethylidene)thiosemicarbazide, 4-substitue-1-(arylcarbonyl)thiosemicarbazide et analogues en tant qu'activateurs de capsases et declencheurs d'apoptose, et leur utilisation
GB0125492D0 (en) * 2001-10-24 2001-12-12 Astrazeneca Ab Formulation
EP2817350A2 (fr) * 2012-02-22 2014-12-31 Merck Patent GmbH Polymères contenant des unités structurales sous forme de dibenzocycloheptane

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2854128C3 (de) * 1978-12-15 1982-02-18 Licentia Patent-Verwaltungs-Gmbh, 6000 Frankfurt Empfängerschaltung mit Verbesserung des Signal-Rauschabstandes
EP0013607B1 (fr) * 1979-01-05 1983-03-23 National Research Development Corporation Bicyclo (2,2,1)heptanes et bicyclo (2,2,1) hept-2-ènes substitués et leurs compositions pharmaceutiques
GB2039480B (en) * 1979-01-05 1983-06-15 Jones R Prostaglandins
EP0013608B1 (fr) * 1979-01-05 1983-06-15 National Research Development Corporation Bicyclo (2,2,1)heptanes et hept-2-ènes substitués et leurs compositions pharmaceutiques
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
DE3280020D1 (en) * 1981-12-23 1989-12-21 Nat Res Dev Prostaglandins
US4418076A (en) * 1982-05-03 1983-11-29 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane hydrazone prostaglandin analogs useful in treating thrombolytic diseases
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
US4456615A (en) * 1982-10-25 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4536510A (en) * 1983-07-22 1985-08-20 Smith Kline Beckman Corporation Method of antagonizing the effects of thromboxane
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease

Also Published As

Publication number Publication date
EP0336522A3 (fr) 1990-03-21
DK442186D0 (da) 1986-09-15
EP0336522A2 (fr) 1989-10-11
CA1269936A (fr) 1990-06-05
WO1986004234A3 (fr) 1986-09-12
DE3671167D1 (de) 1990-06-21
IE860132L (en) 1986-07-16
GB2169803B (en) 1989-08-31
US4902717A (en) 1990-02-20
WO1986004234A2 (fr) 1986-07-31
GB2169803A (en) 1986-07-23
EP0208755A1 (fr) 1987-01-21
AU5317486A (en) 1986-08-13
GB8501035D0 (en) 1985-02-20
EP0208755B1 (fr) 1990-05-16
GB8601017D0 (en) 1986-02-19
DK442186A (da) 1986-11-17
AU594660B2 (en) 1990-03-15
JPS62501500A (ja) 1987-06-18

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