ZA858935B - Process for the manufacture of silibinin free of isosilybin and pharmaceuticals containing silibinin - Google Patents
Process for the manufacture of silibinin free of isosilybin and pharmaceuticals containing silibininInfo
- Publication number
- ZA858935B ZA858935B ZA858935A ZA858935A ZA858935B ZA 858935 B ZA858935 B ZA 858935B ZA 858935 A ZA858935 A ZA 858935A ZA 858935 A ZA858935 A ZA 858935A ZA 858935 B ZA858935 B ZA 858935B
- Authority
- ZA
- South Africa
- Prior art keywords
- silibinin
- isosilybin
- manufacture
- free
- pharmaceuticals containing
- Prior art date
Links
- SEBFKMXJBCUCAI-UHFFFAOYSA-N NSC 227190 Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC=C(C=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-UHFFFAOYSA-N 0.000 title 2
- SEBFKMXJBCUCAI-HKTJVKLFSA-N silibinin Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 title 2
- 229950000628 silibinin Drugs 0.000 title 2
- 235000014899 silybin Nutrition 0.000 title 2
- FDQAOULAVFHKBX-KMRPREKFSA-N (+)-Isosilybin A Natural products C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC(=CC=C3O2)[C@@H]2[C@@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 FDQAOULAVFHKBX-KMRPREKFSA-N 0.000 title 1
- FDQAOULAVFHKBX-HKTJVKLFSA-N (2r,3r)-3,5,7-trihydroxy-2-[(2r,3r)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC(=CC=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 FDQAOULAVFHKBX-HKTJVKLFSA-N 0.000 title 1
- KDMGQPNVTKUNHV-UHFFFAOYSA-N Isosilybin Natural products C1=C(O)C(OC)=CC=C1C1C(CO)OC2=CC=C(C3C(C(=O)C4=C(O)C=C(O)C=C4O3)O)C=C2O1 KDMGQPNVTKUNHV-UHFFFAOYSA-N 0.000 title 1
- FDQAOULAVFHKBX-UHFFFAOYSA-N Isosilybin A Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC(=CC=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 FDQAOULAVFHKBX-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3442641 | 1984-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA858935B true ZA858935B (en) | 1986-08-27 |
Family
ID=6250904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA858935A ZA858935B (en) | 1984-11-22 | 1985-11-21 | Process for the manufacture of silibinin free of isosilybin and pharmaceuticals containing silibinin |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS61197579A (enrdf_load_stackoverflow) |
| DD (2) | DD258231A1 (enrdf_load_stackoverflow) |
| ZA (1) | ZA858935B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI529167B (zh) * | 2009-05-14 | 2016-04-11 | 歐羅梅德股份有限公司 | 用於治療病毒性肝炎之非晶型水飛薊賓 |
-
1985
- 1985-11-20 DD DD28304385A patent/DD258231A1/de not_active IP Right Cessation
- 1985-11-20 DD DD30516385A patent/DD262429A1/de not_active IP Right Cessation
- 1985-11-21 ZA ZA858935A patent/ZA858935B/xx unknown
- 1985-11-22 JP JP60261630A patent/JPS61197579A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DD262429A1 (de) | 1988-11-30 |
| DD258231A1 (de) | 1988-07-13 |
| JPS61197579A (ja) | 1986-09-01 |
| JPH0339506B2 (enrdf_load_stackoverflow) | 1991-06-14 |
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