ZA857932B - Combination of dihydropyridines with ace inhibitors and their use in medicaments - Google Patents

Combination of dihydropyridines with ace inhibitors and their use in medicaments

Info

Publication number
ZA857932B
ZA857932B ZA857932A ZA857932A ZA857932B ZA 857932 B ZA857932 B ZA 857932B ZA 857932 A ZA857932 A ZA 857932A ZA 857932 A ZA857932 A ZA 857932A ZA 857932 B ZA857932 B ZA 857932B
Authority
ZA
South Africa
Prior art keywords
combination
dihydropyridines
medicaments
ace inhibitors
angiotensin
Prior art date
Application number
ZA857932A
Inventor
Bernward Gathoff
Stanislav Kazda
Andreas Knorr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6248017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA857932(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA857932B publication Critical patent/ZA857932B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention concerns a combination of dihydropyridine derivatives with compounds which inhibit the formation of enzymes which control the conversion of angiotensin I into angiotensin II and their use as antihypertensive agents.
ZA857932A 1984-10-17 1985-10-16 Combination of dihydropyridines with ace inhibitors and their use in medicaments ZA857932B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843437917 DE3437917A1 (en) 1984-10-17 1984-10-17 COMBINATION OF DIHYDROPYRIDINE WITH ACE INHIBITORS AND THEIR USE IN MEDICINAL PRODUCTS

Publications (1)

Publication Number Publication Date
ZA857932B true ZA857932B (en) 1986-05-28

Family

ID=6248017

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA857932A ZA857932B (en) 1984-10-17 1985-10-16 Combination of dihydropyridines with ace inhibitors and their use in medicaments

Country Status (16)

Country Link
US (1) US4703038A (en)
EP (1) EP0180785B1 (en)
JP (1) JPS6197228A (en)
KR (1) KR860003020A (en)
AT (1) ATE44650T1 (en)
AU (1) AU4840085A (en)
CA (1) CA1251733A (en)
DD (1) DD239525A5 (en)
DE (2) DE3437917A1 (en)
DK (1) DK473585A (en)
ES (1) ES8703089A1 (en)
GR (1) GR852493B (en)
HU (1) HU194053B (en)
IL (1) IL76697A0 (en)
PT (1) PT81308B (en)
ZA (1) ZA857932B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3542794A1 (en) * 1985-12-04 1987-06-11 Bayer Ag ANTI-HYPERTENSIVE COMBINATION PREPARATION
DE3629060A1 (en) * 1986-08-27 1988-03-03 Bayer Ag COMBINATION OF POSITIVELY INOTROP ACTING DIHYDROPYRIDINES WITH ACE INHIBITORS, AND THEIR USE IN MEDICINAL PRODUCTS
EP0259838A3 (en) * 1986-09-09 1989-11-15 Syntex (U.S.A.) Inc. Pharmaceutical composition containing a 1,4-dihydropyridine derivative and an acylated 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
DE3633496A1 (en) * 1986-10-02 1988-04-14 Hoechst Ag COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS WITH CALCIUMANTAGONISTS AND THEIR USE IN MEDICINAL PRODUCTS
DE3636123A1 (en) * 1986-10-23 1988-05-05 Rentschler Arzneimittel ORAL ADMINISTRATIVE PREPARATIONS CONTAINING SINGLE DOSE FROM 10 TO 240 MG DIHYDROPYRIDINE
HU199681B (en) * 1986-11-03 1990-03-28 Sandoz Ag Process for producing new pharmaceutical composition against hypertension and atonic cardiac decomposition
USH734H (en) * 1988-03-07 1990-02-06 E. R. Squibb & Sons, Inc. Method for inhibiting onset of or treating migraine headaches employing an ACE inhibitor
JPH01275529A (en) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc Suppressing treatment agent of delayed motion effect
DE3818245A1 (en) * 1988-05-28 1989-12-07 Hoechst Ag COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS WITH COLD CHANNEL MODULATORS AND THEIR USE IN MEDICINAL PRODUCTS
JP2919607B2 (en) * 1989-03-22 1999-07-12 ピーター ケー テイー パング Parasyloid hypertensive factor
US5350771A (en) * 1989-03-22 1994-09-27 Peter K. T. Pang Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
US5886012A (en) * 1989-03-22 1999-03-23 Peter K. T. Pang Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers
TW197945B (en) * 1990-11-27 1993-01-11 Hoechst Ag
ATE180972T1 (en) * 1990-12-17 1999-06-15 Gosbert Dr Med Dr Rer Nat Weth USE OF N-(AMINOACYL)-AMINO ACIDS FOR PRODUCING DOPAMINERGIC AND GONADOTROPIC DRUGS.
US6162802A (en) * 1992-03-10 2000-12-19 Papa; Joseph Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
ES2125198B1 (en) * 1997-05-13 1999-11-16 Vita Invest Sa FIXED-DOSE ASSOCIATION OF AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR AND AN ANTAGONIST OF THE CALCIUM CHANNELS, PROCEDURE FOR ITS PREPARATION AND USE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES.
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US6569456B2 (en) 2000-01-13 2003-05-27 Osmotica Corp. Osmotic device containing diltiazem and an ACE inhibitor or diuretic
GB0113839D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
GB0318094D0 (en) * 2003-08-01 2003-09-03 Pfizer Ltd Novel combination
US20050032879A1 (en) * 2003-08-07 2005-02-10 Temple Okarter Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases
WO2005037317A2 (en) * 2003-10-17 2005-04-28 Cornell Research Foundation, Inc. Mast cell-derived renin
US10517839B2 (en) * 2008-06-09 2019-12-31 Cornell University Mast cell inhibition in diseases of the retina and vitreous

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966948A (en) * 1970-01-24 1976-06-29 Bayer Aktiengesellschaft Spasmolytic, vaso-dilating and anti-hypertensive compositions and methods
US3971791A (en) * 1972-03-06 1976-07-27 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3966946A (en) * 1973-06-12 1976-06-29 Smith Kline & French Laboratories Limited 1,4-Dihydropyridine compounds in treating hypertension
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US4703038A (en) 1987-10-27
DE3437917A1 (en) 1986-04-17
JPS6197228A (en) 1986-05-15
GR852493B (en) 1986-02-11
CA1251733A (en) 1989-03-28
ES547931A0 (en) 1987-02-01
AU4840085A (en) 1986-04-24
DK473585D0 (en) 1985-10-16
KR860003020A (en) 1986-05-19
DD239525A5 (en) 1986-10-01
EP0180785A1 (en) 1986-05-14
PT81308A (en) 1985-11-01
HUT40331A (en) 1986-12-28
EP0180785B1 (en) 1989-07-19
DE3571550D1 (en) 1989-08-24
ES8703089A1 (en) 1987-02-01
DK473585A (en) 1986-04-18
HU194053B (en) 1988-01-28
ATE44650T1 (en) 1989-08-15
IL76697A0 (en) 1986-02-28
PT81308B (en) 1987-08-05

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