ZA857522B - Pharmaceutical compositions containing diazepines and having a paf-antagonistic activity - Google Patents

Pharmaceutical compositions containing diazepines and having a paf-antagonistic activity

Info

Publication number
ZA857522B
ZA857522B ZA857522A ZA857522A ZA857522B ZA 857522 B ZA857522 B ZA 857522B ZA 857522 A ZA857522 A ZA 857522A ZA 857522 A ZA857522 A ZA 857522A ZA 857522 B ZA857522 B ZA 857522B
Authority
ZA
South Africa
Prior art keywords
diazepines
paf
pharmaceutical compositions
compositions containing
antagonistic activity
Prior art date
Application number
ZA857522A
Inventor
Jorge Casals-Stenzel
Karl-Heinz Weber
Gerhard Walther
Albrecht Harreus
Gojko Muacevic
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA857522B publication Critical patent/ZA857522B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA857522A 1984-10-01 1985-09-30 Pharmaceutical compositions containing diazepines and having a paf-antagonistic activity ZA857522B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843435974 DE3435974A1 (en) 1984-10-01 1984-10-01 PHARMACEUTICAL COMPOSITIONS CONTAINING DIAZEPINE WITH PAF-ANTAGONISTIC EFFECT

Publications (1)

Publication Number Publication Date
ZA857522B true ZA857522B (en) 1987-06-24

Family

ID=6246813

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA857522A ZA857522B (en) 1984-10-01 1985-09-30 Pharmaceutical compositions containing diazepines and having a paf-antagonistic activity

Country Status (6)

Country Link
US (1) US4623646A (en)
EP (1) EP0176928A3 (en)
JP (1) JPS6187623A (en)
DE (1) DE3435974A1 (en)
PH (1) PH22659A (en)
ZA (1) ZA857522B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4667545A (en) * 1985-06-03 1987-05-26 Gould Jr Frederick H Screw gun automatic feed
JPS6485978A (en) * 1987-06-09 1989-03-30 Yoshitomi Pharmaceutical Novel thienodiazepine derivative
US4959361A (en) * 1987-12-18 1990-09-25 Hoffmann-La Roche Inc. Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists
EP0384421A3 (en) * 1989-02-23 1992-02-12 Boehringer Ingelheim Kg Use of paf antagonists in the treatment of pathologic changes of the blood gas
JPH0525145A (en) * 1991-07-15 1993-02-02 Mochida Pharmaceut Co Ltd Agent for treatment of allergic disease
WO1999058117A1 (en) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Use of compounds for reducing apoptosis
FR2778564B1 (en) * 1998-05-13 2001-07-13 Sanofi Sa USE OF COMPOUNDS REDUCING APOPTOSIS
FR2791980B1 (en) * 1999-04-09 2001-07-06 Sod Conseils Rech Applic PYRIDO-THIENO-DIAZEPINES, THEIR PREPARATION PROCESS, AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US20050113460A1 (en) * 1999-04-30 2005-05-26 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US20060025388A1 (en) * 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
ES2214273T3 (en) * 1999-04-30 2004-09-16 The Regents Of The University Of Michigan USE OF BENZODIAZEPINS FOR THE TREATMENT OF AUTOIMMUNE DISEASES INDUCED BY APOPTOSIS.
US7572788B2 (en) * 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
WO2000066096A2 (en) * 1999-04-30 2000-11-09 Merab Lomia Use of antiepileptics for treating respiratory disorders, in particular asthmatic disorders
US20090275099A1 (en) * 2004-04-27 2009-11-05 Regents Of The University Of Michigan Methods and compositions for treating diseases and conditions associated with mitochondrial function
US20050272723A1 (en) * 2004-04-27 2005-12-08 The Regents Of The University Of Michigan Methods and compositions for treating diseases and conditions associated with mitochondrial function
US20060052369A1 (en) * 2004-09-07 2006-03-09 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
JP2008545757A (en) * 2005-06-01 2008-12-18 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Unsolvated benzodiazepine compositions and methods
US20070105844A1 (en) * 2005-10-26 2007-05-10 Regents Of The University Of Michigan Therapeutic compositions and methods
JP5241501B2 (en) * 2005-11-01 2013-07-17 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) * 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
EP2037741B1 (en) 2006-06-09 2013-11-27 The Regents Of The University Of Michigan Benzodiazepine derivatives for use in the treatment of immune, inflammatory and proliferative disorders
EP2139331B1 (en) * 2007-03-09 2013-02-20 The Regents of the University of Michigan Compositions and methods relating to novel compounds and targets thereof
CN101855203B (en) * 2007-09-14 2014-03-19 密执安州立大学董事会 F1F0-ATPase inhibitors and related methods
CA2703005A1 (en) 2007-11-06 2009-05-14 The Regents Of The University Of Michigan Benzodiazepinone compounds useful in the treatment of skin conditions
WO2010030891A2 (en) 2008-09-11 2010-03-18 The Regents Of The University Of Michigan Aryl guanidine f1f0-atpase inhibitors and related methods
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
US8673897B2 (en) 2009-09-18 2014-03-18 The Regents Of The University Of Michigan Benzodiazepinone compounds and methods of treatment using same
CA2915237C (en) 2009-11-17 2017-10-10 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
JP5856064B2 (en) 2009-11-17 2016-02-09 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 1,4-Benzodiazepine-2,5-dione and related compounds having therapeutic properties
CN108640922B (en) * 2018-06-14 2019-08-30 沈阳药科大学 Triazole and diazepine -5- ketone compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3934018A (en) * 1970-09-03 1976-01-20 Abbott Laboratories 4,6-Dihydro-1,3-dimethyl-8-phenylpyrazolo[4,3-e] [1,4]diazepin-5-(1H)-one and derivatives as anti-inflammatory agents
GB1371693A (en) * 1972-02-10 1974-10-23 Abbott Lab 4,6-dihydro-1,3-dimethyl-4-ethyl-8-phenylpyrazolo-4,3-e-1,4- diazepin-5-1h-one and compositions containing the same

Also Published As

Publication number Publication date
JPS6187623A (en) 1986-05-06
EP0176928A3 (en) 1990-09-05
PH22659A (en) 1988-11-14
EP0176928A2 (en) 1986-04-09
US4623646A (en) 1986-11-18
DE3435974A1 (en) 1986-04-10

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