ZA851160B - Novel acidic polycyclic ether antibiotic - Google Patents

Novel acidic polycyclic ether antibiotic

Info

Publication number
ZA851160B
ZA851160B ZA851160A ZA851160A ZA851160B ZA 851160 B ZA851160 B ZA 851160B ZA 851160 A ZA851160 A ZA 851160A ZA 851160 A ZA851160 A ZA 851160A ZA 851160 B ZA851160 B ZA 851160B
Authority
ZA
South Africa
Prior art keywords
antibiotic
polycyclic ether
acidic polycyclic
ether antibiotic
novel acidic
Prior art date
Application number
ZA851160A
Inventor
Walter Daniel Celmer
Walter Patrick Cullen
Hiroshi Maeda
Junsuke Tone
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA851160B publication Critical patent/ZA851160B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/195Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/445The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Husbandry (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Fodder In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)

Abstract

A new acidic polycyclic ether antibiotic, CP-63,517, having the formula:and cationic salts thereof produced by submerged aerobic propagation of Streptomyces endus subsp. aureus, ATCC-39574, a new strain of microorganism isolated from a soil sample in Japan, a process for producing this antibiotic and methods for its use to improve feed utilization, promote growth of cattle and swine and to control coccidiosis.
ZA851160A 1984-02-17 1985-02-15 Novel acidic polycyclic ether antibiotic ZA851160B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/581,384 US4552843A (en) 1984-02-17 1984-02-17 Process for producing an acidic polycyclic ether antibiotic by cultivation of a novel strain of Streptomyces endus subspecies aureus

Publications (1)

Publication Number Publication Date
ZA851160B true ZA851160B (en) 1986-10-29

Family

ID=24324993

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA851160A ZA851160B (en) 1984-02-17 1985-02-15 Novel acidic polycyclic ether antibiotic

Country Status (25)

Country Link
US (1) US4552843A (en)
EP (1) EP0153128B1 (en)
JP (1) JPS60199895A (en)
KR (1) KR870000236B1 (en)
AT (1) ATE41424T1 (en)
AU (1) AU552957B2 (en)
CA (1) CA1234771A (en)
DE (1) DE3568781D1 (en)
DK (1) DK158988C (en)
ES (1) ES8605861A1 (en)
FI (1) FI78118C (en)
GR (1) GR850399B (en)
HU (1) HU194311B (en)
IE (1) IE58131B1 (en)
IL (1) IL74353A (en)
MX (1) MX164678B (en)
NO (1) NO164422C (en)
NZ (1) NZ211133A (en)
PH (1) PH19992A (en)
PL (1) PL145197B1 (en)
PT (1) PT79974B (en)
SU (1) SU1431682A3 (en)
YU (1) YU43398B (en)
ZA (1) ZA851160B (en)
ZW (1) ZW2085A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510317A (en) * 1983-07-28 1985-04-09 Hoffmann-La Roche Inc. Antibiotic X-14934A
US5242814A (en) * 1989-10-10 1993-09-07 Eli Lilly And Company Polyether antibiotic
US5573724A (en) * 1994-07-29 1996-11-12 Magneco/Metrel, Inc. Ladle port assembly

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5592387A (en) * 1978-12-29 1980-07-12 Taisho Pharmaceut Co Ltd Antibiotic substance tm-531
JPS574975A (en) * 1980-06-12 1982-01-11 Kyowa Hakko Kogyo Co Ltd Phenazine derivative and its preparation
US4359583A (en) * 1980-09-16 1982-11-16 Taisho Pharmaceutical Co., Ltd. Antibiotics TM-531 B and TM-531 C
JPS5758687A (en) * 1980-09-27 1982-04-08 Taisho Pharmaceut Co Ltd Antibiotic
US4361649A (en) * 1981-07-20 1982-11-30 Pfizer Inc. Polycyclic ether antibiotic

Also Published As

Publication number Publication date
EP0153128A2 (en) 1985-08-28
ATE41424T1 (en) 1989-04-15
ZW2085A1 (en) 1985-05-22
GR850399B (en) 1985-06-14
IE58131B1 (en) 1993-07-14
HUT37655A (en) 1986-01-23
JPS643875B2 (en) 1989-01-23
FI850650A0 (en) 1985-02-15
PL251964A1 (en) 1985-11-19
IE850381L (en) 1985-08-17
HU194311B (en) 1988-01-28
NO164422C (en) 1990-10-03
NO164422B (en) 1990-06-25
NZ211133A (en) 1988-04-29
ES8605861A1 (en) 1986-04-01
IL74353A (en) 1987-12-20
DK158988B (en) 1990-08-13
IL74353A0 (en) 1985-05-31
JPS60199895A (en) 1985-10-09
FI78118C (en) 1989-06-12
DK71285D0 (en) 1985-02-15
SU1431682A3 (en) 1988-10-15
PL145197B1 (en) 1988-08-31
PT79974B (en) 1987-02-02
PT79974A (en) 1985-03-01
US4552843A (en) 1985-11-12
YU43398B (en) 1989-06-30
AU3875985A (en) 1985-08-22
YU6485A (en) 1987-12-31
FI78118B (en) 1989-02-28
DK71285A (en) 1985-08-18
FI850650L (en) 1985-08-18
CA1234771A (en) 1988-04-05
ES540399A0 (en) 1986-04-01
DE3568781D1 (en) 1989-04-20
EP0153128A3 (en) 1987-01-21
KR870000236B1 (en) 1987-02-18
KR850006873A (en) 1985-10-21
DK158988C (en) 1991-01-07
AU552957B2 (en) 1986-06-26
PH19992A (en) 1986-08-28
EP0153128B1 (en) 1989-03-15
NO850609L (en) 1985-08-19
MX164678B (en) 1992-09-14

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