ZA838913B - 2-(4-tert.-butyl-2,6-dichlorophenylimino)imidazolidine - Google Patents

2-(4-tert.-butyl-2,6-dichlorophenylimino)imidazolidine

Info

Publication number
ZA838913B
ZA838913B ZA838913A ZA838913A ZA838913B ZA 838913 B ZA838913 B ZA 838913B ZA 838913 A ZA838913 A ZA 838913A ZA 838913 A ZA838913 A ZA 838913A ZA 838913 B ZA838913 B ZA 838913B
Authority
ZA
South Africa
Prior art keywords
dichlorophenylimino
imidazolidine
tert
butyl
Prior art date
Application number
ZA838913A
Other languages
English (en)
Inventor
Robert Michael Demarinis
Jacob Paul Hieble
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA838913B publication Critical patent/ZA838913B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA838913A 1982-12-23 1983-11-30 2-(4-tert.-butyl-2,6-dichlorophenylimino)imidazolidine ZA838913B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/452,676 US4444782A (en) 1982-12-23 1982-12-23 2(4-tert.-Butyl-2,6-dichlorophenyl-imino)imidazolidine and use as an anti-hypertension agent

Publications (1)

Publication Number Publication Date
ZA838913B true ZA838913B (en) 1985-02-27

Family

ID=23797446

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA838913A ZA838913B (en) 1982-12-23 1983-11-30 2-(4-tert.-butyl-2,6-dichlorophenylimino)imidazolidine

Country Status (10)

Country Link
US (1) US4444782A (cs)
EP (1) EP0116768A1 (cs)
JP (1) JPS59118770A (cs)
AU (1) AU569583B2 (cs)
CA (1) CA1199926A (cs)
DK (1) DK565083A (cs)
ES (1) ES528306A0 (cs)
GR (1) GR79478B (cs)
PT (1) PT77861B (cs)
ZA (1) ZA838913B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801617A (en) * 1987-04-06 1989-01-31 Leclerc Gerard Iminoimidazolidines useful in lowering intraocular pressure
US4897412A (en) * 1987-04-06 1990-01-30 Laboratories Alcon S.A. Imidazolines useful in lowering intraocular pressure
DE69500313T2 (de) * 1994-02-08 1997-11-06 Alcon Laboratories, Inc., Fort Worth, Tex. Neues verfahren zur herstellung von clonidin-derivaten
US20020169193A1 (en) * 2001-02-10 2002-11-14 Pascale Pouzet Alkylphenyliminoimidazolidine derivatives for treating urinary incontinence

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
NL123037C (cs) * 1963-10-04
AT285599B (de) * 1968-06-21 1970-11-10 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen trisubstituierten 2-Arylaminoimidazolinen und ihren Salzen
US4287201A (en) * 1980-03-03 1981-09-01 Merck & Co., Inc. Anovulatory method and chicken feed compositions
DE3168754D1 (en) * 1980-07-09 1985-03-21 Beecham Group Plc Clonidine derivatives useful in the treatment of diarrhoea

Also Published As

Publication number Publication date
DK565083A (da) 1984-06-24
ES8506640A1 (es) 1985-08-01
JPS59118770A (ja) 1984-07-09
EP0116768A1 (en) 1984-08-29
PT77861B (en) 1986-04-09
PT77861A (en) 1984-01-01
AU2197883A (en) 1984-06-28
CA1199926A (en) 1986-01-28
AU569583B2 (en) 1988-02-11
ES528306A0 (es) 1985-08-01
US4444782A (en) 1984-04-24
DK565083D0 (da) 1983-12-08
GR79478B (cs) 1984-10-30

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