ZA83567B - Diphosphonic acid derivatives, process for their preparation and pharmaceutical preparation containing them - Google Patents

Diphosphonic acid derivatives, process for their preparation and pharmaceutical preparation containing them

Info

Publication number
ZA83567B
ZA83567B ZA83567A ZA83567A ZA83567B ZA 83567 B ZA83567 B ZA 83567B ZA 83567 A ZA83567 A ZA 83567A ZA 83567 A ZA83567 A ZA 83567A ZA 83567 B ZA83567 B ZA 83567B
Authority
ZA
South Africa
Prior art keywords
preparation
acid derivatives
diphosphonic acid
pharmaceutical preparation
preparation containing
Prior art date
Application number
ZA83567A
Inventor
Helmut Biere
Clemens Rufer
Irmgard Boettcher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA83567B publication Critical patent/ZA83567B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3882Arylalkanephosphonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/386Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4025Esters of poly(thio)phosphonic acids
    • C07F9/404Esters of poly(thio)phosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056Esters of arylalkanephosphonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA83567A 1982-01-27 1983-01-27 Diphosphonic acid derivatives, process for their preparation and pharmaceutical preparation containing them ZA83567B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823203309 DE3203309A1 (en) 1982-01-27 1982-01-27 DIPHOSPHONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
ZA83567B true ZA83567B (en) 1983-10-26

Family

ID=6154494

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA83567A ZA83567B (en) 1982-01-27 1983-01-27 Diphosphonic acid derivatives, process for their preparation and pharmaceutical preparation containing them

Country Status (5)

Country Link
JP (1) JPS58174394A (en)
DE (1) DE3203309A1 (en)
GB (1) GB2113687A (en)
IE (1) IE54136B1 (en)
ZA (1) ZA83567B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3428524A1 (en) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim NEW DIPHOSPHONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
JPH0377894A (en) * 1989-08-18 1991-04-03 Toray Ind Inc Methylene diphosphonic acid compound
DE69330114T2 (en) * 1992-07-10 2001-08-02 Toray Industries, Inc. METHANDIPHOSPHONATE DERIVATIVE, THEIR PRODUCTION AND THE USE THEREOF AS A MEDICINAL PRODUCT
JPH06135976A (en) * 1992-10-30 1994-05-17 Toray Ind Inc Methanediphosphonic acid derivative, its production and medicinal use thereof
EP1219607B1 (en) * 1999-09-02 2011-04-06 Shionogi & Co., Ltd. Integrase inhibitors containing aromatic heterocycle derivatives

Also Published As

Publication number Publication date
JPH0329078B2 (en) 1991-04-23
GB8302176D0 (en) 1983-03-02
IE830148L (en) 1983-07-27
IE54136B1 (en) 1989-06-21
JPS58174394A (en) 1983-10-13
DE3203309A1 (en) 1983-07-28
GB2113687A (en) 1983-08-10

Similar Documents

Publication Publication Date Title
IL67763A0 (en) Diphosphonic acid derivatives,process for their preparation and pharmaceutical preparations containing them
DE3166619D1 (en) 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridine-3-carboxylic acids, process for their preparation and pharmaceutical compositions containing them
DE3263633D1 (en) Imidazodiazepines, process for their preparation and pharmaceutical compositions containing them
DE3477922D1 (en) -1-benzyl-aminoalkyl-pyrrolidinones and their addition salts, process for their preparation and pharmaceutical compounds containing them
DE3461090D1 (en) 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them
ZA859035B (en) Amino-salicylic acid derivatives,salts thereof,process for their preparation and pharmaceutical compositions containing them
EP0145121A3 (en) Pyrazoloquinolines, process for their preparation, and pharmaceutical compositions containing them
ZA84439B (en) Amino acid derivatives,process for their preparation and pharmaceutical preparations containing them
IL65247A0 (en) Amido-amino acids,process for their preparation and pharmaceutical compositions containing them
DE3166656D1 (en) 1-phenyl-2-cyclohexene-1-alkylamine derivatives, process for their preparation and medicines containing them
EP0084822A3 (en) Diphosphonic acid derivatives and pharmaceutical preparations containing them
IL69735A (en) 1-phenyl-1-aminoalkyl-cyclobutane derivatives,process for their preparation and pharmaceutical compositions containing them
IL69164A0 (en) Diphosphonic acid derivatives,processes for the manufacture thereof and pharmaceutical preparations containing the same
EP0168042A3 (en) Dihydroorotic acid derivatives, processes for their preparing and pharmaceutical composition containing them
ZA83567B (en) Diphosphonic acid derivatives, process for their preparation and pharmaceutical preparation containing them
GB2138817B (en) 4-pheny-tetrahydro-furano-pyridines, process for their preparation, and pharmaceutical compositions containing them
DE3380875D1 (en) Piperidine-3-carboxylic acid derivatives, process for their preparation, and pharmaceutical compositions containing them
IL69105A0 (en) Apovincaminic acid derivatives,process for their preparation and pharmaceutical compositions containing them
ZA855245B (en) Aminoeburnanecarboxylic acid derivatives,pharmaceutical compositions containing them and process for preparing same
DE3368046D1 (en) Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
ZA855244B (en) Nitrovincaminic acid derivatives,pharmaceutical compositions containing them and process for preparing same
IL69107A (en) 15-hydroxyimino-14-oxo-eburnamenine derivatives,process for their preparation and pharmaceutical compositions containing these compounds
IL62890A0 (en) Alkoxy-acyl carnitines,process for their preparation and pharmaceutical compositions containing same
ZA834917B (en) Phenylacetic acid derivatives,processes for their preparation,and pharmaceutical compositions thereof
DE3271206D1 (en) Inter-m-phenylene-pgi2 derivatives, process for their preparation and pharmaceutical compositions containing them