ZA832389B - 4h-thopyrans,process for their preparation and their use in medicaments - Google Patents
4h-thopyrans,process for their preparation and their use in medicamentsInfo
- Publication number
- ZA832389B ZA832389B ZA832389A ZA832389A ZA832389B ZA 832389 B ZA832389 B ZA 832389B ZA 832389 A ZA832389 A ZA 832389A ZA 832389 A ZA832389 A ZA 832389A ZA 832389 B ZA832389 B ZA 832389B
- Authority
- ZA
- South Africa
- Prior art keywords
- carbon atoms
- phenyl
- alkyl radical
- represent
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Paper (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Glass Compositions (AREA)
- Dental Preparations (AREA)
- Materials For Medical Uses (AREA)
- Luminescent Compositions (AREA)
Abstract
1. Thiopyrans of the general formula (I) see diagramm : EP0091051,P9,F2 in which R represents phenyl, naphthyl, furyl, pyrryl or pyridyl, these rings optionally containing 1, 2 or 3 identical or different substituents from the group comprising alkyl, alkenyl, alkinyl, alkoxy, alkylene, alkylenedioxy, alkylamino, each having up to 4 carbon atoms, phenyl, halogen, trifluoromethyl, trifluoromethoxy, nitro, cyano or azido, R**1 , R**3 and R**4 are identical or different and each represent hydrogen, an alkyl radical with up to 6 carbon atoms or one of the radicals mentioned under R, it being possible for R**4 also to represent a single bond to R with the formation of a 6- to 7-membered lactone ring ; R**2 represents hydrogen, an alkyl radical with up to 4 carbon atoms, phenyl or aminoalkyl with up to 4 carbon atoms, and X represents O, S or -NH-, and their pharmaceutically acceptable acid addition salts.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823212737 DE3212737A1 (en) | 1982-04-06 | 1982-04-06 | 4H-THIOPYRANS, METHOD FOR THEIR PRODUCTION AND THEIR USE IN MEDICINAL PRODUCTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA832389B true ZA832389B (en) | 1983-12-28 |
Family
ID=6160333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA832389A ZA832389B (en) | 1982-04-06 | 1983-04-05 | 4h-thopyrans,process for their preparation and their use in medicaments |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0091051B1 (en) |
| JP (1) | JPS58183685A (en) |
| KR (1) | KR840004423A (en) |
| AT (1) | ATE24003T1 (en) |
| CA (1) | CA1198107A (en) |
| DE (2) | DE3212737A1 (en) |
| DK (1) | DK151883A (en) |
| ES (1) | ES8401975A1 (en) |
| IL (1) | IL68283A0 (en) |
| ZA (1) | ZA832389B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2310128A2 (en) * | 1975-05-06 | 1976-12-03 | Little Inc A | Thieno-and thio-pyrano-benzopyran CNS active derivs - used as anti-anxiety agents and tranquillizers |
| US4198426A (en) * | 1977-11-28 | 1980-04-15 | Ayerst Mckenna & Harrison Ltd. | 2-Substituted-3-methyl-γ-pyrone tricyclic derivatives |
-
1982
- 1982-04-06 DE DE19823212737 patent/DE3212737A1/en not_active Withdrawn
-
1983
- 1983-03-28 AT AT83103043T patent/ATE24003T1/en not_active IP Right Cessation
- 1983-03-28 DE DE8383103043T patent/DE3368058D1/en not_active Expired
- 1983-03-28 EP EP83103043A patent/EP0091051B1/en not_active Expired
- 1983-03-31 CA CA000425122A patent/CA1198107A/en not_active Expired
- 1983-03-31 JP JP58054076A patent/JPS58183685A/en active Pending
- 1983-04-01 IL IL68283A patent/IL68283A0/en unknown
- 1983-04-04 KR KR1019830001396A patent/KR840004423A/en not_active Application Discontinuation
- 1983-04-05 ES ES521233A patent/ES8401975A1/en not_active Expired
- 1983-04-05 ZA ZA832389A patent/ZA832389B/en unknown
- 1983-04-05 DK DK151883A patent/DK151883A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0091051A3 (en) | 1984-07-25 |
| EP0091051A2 (en) | 1983-10-12 |
| DE3212737A1 (en) | 1983-10-06 |
| CA1198107A (en) | 1985-12-17 |
| EP0091051B1 (en) | 1986-12-03 |
| IL68283A0 (en) | 1983-07-31 |
| DK151883A (en) | 1983-10-07 |
| ES521233A0 (en) | 1984-01-01 |
| ES8401975A1 (en) | 1984-01-01 |
| JPS58183685A (en) | 1983-10-26 |
| DE3368058D1 (en) | 1987-01-15 |
| KR840004423A (en) | 1984-10-15 |
| ATE24003T1 (en) | 1986-12-15 |
| DK151883D0 (en) | 1983-04-05 |
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