ZA818905B - Vinblastine oxazolidinedione disulfides and related compounds - Google Patents
Vinblastine oxazolidinedione disulfides and related compoundsInfo
- Publication number
- ZA818905B ZA818905B ZA818905A ZA818905A ZA818905B ZA 818905 B ZA818905 B ZA 818905B ZA 818905 A ZA818905 A ZA 818905A ZA 818905 A ZA818905 A ZA 818905A ZA 818905 B ZA818905 B ZA 818905B
- Authority
- ZA
- South Africa
- Prior art keywords
- oxazolidinedione
- disulfides
- vinblastine
- related compounds
- compounds
- Prior art date
Links
- JXLYSJRDGCGARV-WWYNWVTFSA-N Vinblastine Natural products O=C(O[C@H]1[C@](O)(C(=O)OC)[C@@H]2N(C)c3c(cc(c(OC)c3)[C@]3(C(=O)OC)c4[nH]c5c(c4CCN4C[C@](O)(CC)C[C@H](C3)C4)cccc5)[C@@]32[C@H]2[C@@]1(CC)C=CCN2CC3)C JXLYSJRDGCGARV-WWYNWVTFSA-N 0.000 title 1
- -1 Vinblastine oxazolidinedione disulfides Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229960003048 vinblastine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/220,472 US4362664A (en) | 1980-12-29 | 1980-12-29 | Vinblastine oxazolidinedione disulfides and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA818905B true ZA818905B (en) | 1983-08-31 |
Family
ID=22823667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA818905A ZA818905B (en) | 1980-12-29 | 1981-12-23 | Vinblastine oxazolidinedione disulfides and related compounds |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4362664A (ref) |
| EP (1) | EP0055602A3 (ref) |
| JP (1) | JPS57134492A (ref) |
| KR (1) | KR830007704A (ref) |
| CA (1) | CA1166246A (ref) |
| GB (1) | GB2090254B (ref) |
| GR (1) | GR75128B (ref) |
| HU (1) | HU186800B (ref) |
| IL (1) | IL64617A0 (ref) |
| ZA (1) | ZA818905B (ref) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4952408A (en) * | 1988-05-23 | 1990-08-28 | Georgetown University | Liposome-encapsulated vinca alkaloids and their use in combatting tumors |
| CN116236461B (zh) * | 2021-12-08 | 2026-03-24 | 深圳先进技术研究院 | 一种氧化还原型纳米颗粒和活细胞载体及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR69783B (ref) * | 1976-09-08 | 1982-07-07 | Lilly Co Eli | |
| USRE30560E (en) | 1976-12-06 | 1981-03-31 | Eli Lilly And Company | Oxazolidinedione derivatives of Vinca alkaloids |
| US4160767A (en) * | 1976-12-06 | 1979-07-10 | Eli Lilly And Company | Vinca alkaloid intermediates |
| US4096148A (en) * | 1976-12-06 | 1978-06-20 | Eli Lilly And Company | Oxazolidinedione derivatives of Vinca alkaloids |
| US4203898A (en) * | 1977-08-29 | 1980-05-20 | Eli Lilly And Company | Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids |
| US4199504A (en) * | 1978-05-15 | 1980-04-22 | Eli Lilly And Company | Bridged cathranthus alkaloid dimers |
-
1980
- 1980-12-29 US US06/220,472 patent/US4362664A/en not_active Expired - Fee Related
-
1981
- 1981-12-11 GR GR66888A patent/GR75128B/el unknown
- 1981-12-22 IL IL64617A patent/IL64617A0/xx unknown
- 1981-12-23 GB GB8138763A patent/GB2090254B/en not_active Expired
- 1981-12-23 CA CA000393076A patent/CA1166246A/en not_active Expired
- 1981-12-23 EP EP81306075A patent/EP0055602A3/en not_active Ceased
- 1981-12-23 ZA ZA818905A patent/ZA818905B/xx unknown
- 1981-12-25 JP JP56216029A patent/JPS57134492A/ja active Pending
- 1981-12-28 HU HU813971A patent/HU186800B/hu unknown
- 1981-12-28 KR KR1019810005165A patent/KR830007704A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US4362664A (en) | 1982-12-07 |
| JPS57134492A (en) | 1982-08-19 |
| EP0055602A2 (en) | 1982-07-07 |
| GR75128B (ref) | 1984-07-13 |
| GB2090254A (en) | 1982-07-07 |
| HU186800B (en) | 1985-09-30 |
| CA1166246A (en) | 1984-04-24 |
| IL64617A0 (en) | 1982-03-31 |
| EP0055602A3 (en) | 1982-10-13 |
| KR830007704A (ko) | 1983-11-04 |
| GB2090254B (en) | 1985-01-09 |
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