ZA818431B - Antimycotic agents which have a good release of active compound and are in the form of elastic liquid plasters - Google Patents

Antimycotic agents which have a good release of active compound and are in the form of elastic liquid plasters

Info

Publication number
ZA818431B
ZA818431B ZA818431A ZA818431A ZA818431B ZA 818431 B ZA818431 B ZA 818431B ZA 818431 A ZA818431 A ZA 818431A ZA 818431 A ZA818431 A ZA 818431A ZA 818431 B ZA818431 B ZA 818431B
Authority
ZA
South Africa
Prior art keywords
weight
isopropyl
vinylpyrrolidone
fatty acid
active compounds
Prior art date
Application number
ZA818431A
Inventor
Bittera M Von
K Buechel
M Plempel
E Regel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA818431B publication Critical patent/ZA818431B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Force Measurement Appropriate To Specific Purposes (AREA)
  • Shovels (AREA)

Abstract

1. Claims for the contracting states : BE, CH, LI, DE, FR, GB, IT, NL, SE Antimycotic agents which have relatively good release of active compounds and contain azole derivatives and customary formulation auxiliaries, characterised in that they contain 2-10% by weight of a spreading agent from the group consisting of isopropyl myristate, isopropyl palmitate, isopropyl stearate, caprylates/caproates of saturated fatty alcohols having the chain length of C12 to C18 , wax-like fatty acid esters, such as synthesized duck uropygial gland fat, silicone oils, isopropyl myristate/isorpopyl palmitate/isopropyl stearate mixture, coconut fatty acid isopropyl ester, 1-8% by weight of a solubilising agent and, as a film-forming agent, a quick-drying polyvinylpyrrolidone, a terpolymer of 30% by weight of vinylpyrrolidone, 40% by weight of vinyl acetate and 30% by weight of vinyl propionate, or a vinylpyrrolidone/vinyl acetate copolymer. 1. Claims for the contracting state : AT Process for the production of antimycotics based on azole derivative active compounds and costumary formulation auxiliaries, characterised in that the active compounds and the formulation auxiliaries are formulated together with 2 to 10% by weight of isopropyl myristate, isopropylpalmitate, isopropyl stearate, caprylates/caproates of saturated fatty alcohols having the chain length of C12 to C18 , waxy fatty acid esters, such as synthesized duck uropygial gland fat, silicone oils, isopropyl myristate/isopropyl palmitate/isopropyl stearate mixture or cocount fatty acid isopropylester as spreading agents, 1 to 8% by weight of solubilising agents, based in each case on the total weight, and a quick drying polyvinylpyrrolidone, a terpolymer of vinylpyrrolidone/vinyl acetate/vinyl propionate in a ratio by weight of 30:40:30, or a vinylpyrrolidone/vinylacetate copolymer as the film-forming agent.
ZA818431A 1980-12-05 1981-12-04 Antimycotic agents which have a good release of active compound and are in the form of elastic liquid plasters ZA818431B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803045914 DE3045914A1 (en) 1980-12-05 1980-12-05 ANTIMYCOTIC AGENTS WITH HIGH ACTIVE SUBSTANCE RELEASE IN THE FORM OF ELASTIC LIQUID PLASTERS

Publications (1)

Publication Number Publication Date
ZA818431B true ZA818431B (en) 1982-11-24

Family

ID=6118423

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA818431A ZA818431B (en) 1980-12-05 1981-12-04 Antimycotic agents which have a good release of active compound and are in the form of elastic liquid plasters

Country Status (12)

Country Link
EP (1) EP0055397B1 (en)
JP (1) JPS57122015A (en)
KR (1) KR880000738B1 (en)
AT (1) ATE9060T1 (en)
AU (1) AU546449B2 (en)
CA (1) CA1175355A (en)
DE (2) DE3045914A1 (en)
DK (1) DK538281A (en)
FI (1) FI813885L (en)
IL (1) IL64436A (en)
NO (1) NO813932L (en)
ZA (1) ZA818431B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3311701A1 (en) * 1983-03-30 1984-10-04 Bayer Ag ANTIMYCOTIC AGENTS WITH HIGH ACTIVE SUBSTANCE RELEASE IN THE FORM OF CREAM
DE3311700A1 (en) * 1983-03-30 1984-10-04 Bayer Ag ANTIMYCOTIC AGENTS WITH HIGH ACTIVE SUBSTANCE RELEASE IN THE FORM OF SOLUTION AND SPRAY
CA1241602A (en) * 1984-02-23 1988-09-06 Ortho Pharmaceutical Corporation Antifungal aerosol solution
FR2568773B1 (en) * 1984-08-10 1989-03-03 Sandoz Lab NEW NASAL ADMINISTRATIVE PHARMACEUTICAL COMPOSITIONS
EP0175671A1 (en) * 1984-08-23 1986-03-26 Kuhlemann & Co. Pharmaceutical preparation and method for the administration of this pharmaceutical preparation
JPS61151117A (en) * 1984-12-25 1986-07-09 Bayer Yakuhin Kk Gelatinous antimycotic preparation
DE3522550A1 (en) * 1985-06-24 1987-01-02 Klinge Co Chem Pharm Fab SPRAYABLE PHARMACEUTICAL PREPARATION FOR TOPICAL APPLICATION
DE3544983A1 (en) * 1985-12-19 1987-06-25 Hoechst Ag ANTIMYCOTIC EFFECTIVE NAIL POLISH
HU200914B (en) * 1987-03-09 1990-09-28 Horvath Gyoengyi Lengyelne Process for producing new medical dosage unit suitable for local treatment of fungus infection of nails
DE3720147A1 (en) * 1987-06-16 1988-12-29 Hoechst Ag ANTIMYCOTICALLY EFFECTIVE NAIL POLISH AND METHOD FOR THE PRODUCTION THEREOF
JPH01230514A (en) * 1987-11-25 1989-09-14 Osaka Aerosol Ind Corp Aerosol type patch external use
DE3802046A1 (en) * 1988-01-25 1989-08-03 Robert P Hielscher Hygiene paper (prevention of dermatomycosis - mycosis pedis)
US5116603A (en) * 1989-01-31 1992-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Oral antifungal preventative, and method of use
JP2555555B2 (en) * 1991-07-03 1996-11-20 武田薬品工業株式会社 Antifungal topical formulation
FR2732223B1 (en) * 1995-03-30 1997-06-13 Sanofi Sa PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL ADMINISTRATION
FR2742989B1 (en) * 1995-12-29 1998-01-23 Adir BIOADHESIVE PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS
WO1997034644A1 (en) * 1996-03-16 1997-09-25 Hoechst Aktiengesellschaft Topical formulations for the treatment of nail psoriasis
IL138889A0 (en) * 1998-04-17 2001-11-25 Bertek Pharm Inc Topical formulations for the treatment of nail fungal diseases
PT1150661E (en) * 1999-02-05 2004-02-27 Cipla Ltd PRODUCT FOR SPRAYING FOR TOPIC APPLICATION
US6962691B1 (en) 1999-05-20 2005-11-08 U & I Pharmaceuticals Ltd. Topical spray compositions
ES2366273T3 (en) 2003-03-21 2011-10-18 Nexmed Holdings, Inc. ANTIFUNGICAL NAIL ENAMEL AND USE PROCEDURE.
BRPI0616765A2 (en) 2005-09-29 2011-06-28 Novartis Ag topical antifungal composition adapted to treat a fungal skin infection, method for treating a dermatophyte skin infection, method for treating skin infection, and process for manufacturing a topical pharmaceutical composition
JP4513921B2 (en) * 2008-12-09 2010-07-28 ソニー株式会社 Optical body and manufacturing method thereof, window material, blind, roll curtain, and shoji
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3476853A (en) * 1965-04-13 1969-11-04 Colgate Palmolive Co Sprayed opaque bandage composition
DE1642063A1 (en) * 1967-11-16 1970-07-16 Henkel & Cie Gmbh Wound dressing spray
DE2430039C2 (en) * 1974-06-22 1983-11-10 Bayer Ag, 5090 Leverkusen Climbazole in cosmetic products
DE2461406C2 (en) * 1974-12-24 1984-06-14 Bayer Ag, 5090 Leverkusen Azolyl- (1) -methanes and their salts, processes for their preparation and medicaments containing them

Also Published As

Publication number Publication date
DE3045914A1 (en) 1982-07-22
KR830007072A (en) 1983-10-14
EP0055397B1 (en) 1984-08-22
IL64436A (en) 1985-03-31
EP0055397A1 (en) 1982-07-07
CA1175355A (en) 1984-10-02
IL64436A0 (en) 1982-03-31
ATE9060T1 (en) 1984-09-15
FI813885L (en) 1982-06-06
KR880000738B1 (en) 1988-05-04
DK538281A (en) 1982-06-06
AU7826181A (en) 1982-06-10
JPS57122015A (en) 1982-07-29
AU546449B2 (en) 1985-09-05
DE3165710D1 (en) 1984-09-27
NO813932L (en) 1982-06-07

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