ZA812698B - 4,5-dihydro-6(pyridinyl)-3-(2h)-pyridazinones useful as cardiotonics and preparation thereof - Google Patents

4,5-dihydro-6(pyridinyl)-3-(2h)-pyridazinones useful as cardiotonics and preparation thereof

Info

Publication number
ZA812698B
ZA812698B ZA00812698A ZA812698A ZA812698B ZA 812698 B ZA812698 B ZA 812698B ZA 00812698 A ZA00812698 A ZA 00812698A ZA 812698 A ZA812698 A ZA 812698A ZA 812698 B ZA812698 B ZA 812698B
Authority
ZA
South Africa
Prior art keywords
cardiotonics
pyridazinones
pyridinyl
dihydro
useful
Prior art date
Application number
ZA00812698A
Inventor
G Lesher
W Dickinson
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ZA812698B publication Critical patent/ZA812698B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00812698A 1980-04-28 1981-04-24 4,5-dihydro-6(pyridinyl)-3-(2h)-pyridazinones useful as cardiotonics and preparation thereof ZA812698B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14456480A 1980-04-28 1980-04-28

Publications (1)

Publication Number Publication Date
ZA812698B true ZA812698B (en) 1982-04-28

Family

ID=22509146

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00812698A ZA812698B (en) 1980-04-28 1981-04-24 4,5-dihydro-6(pyridinyl)-3-(2h)-pyridazinones useful as cardiotonics and preparation thereof

Country Status (6)

Country Link
JP (1) JPS572284A (en)
KR (1) KR830005202A (en)
AU (1) AU6991781A (en)
BE (1) BE888567A (en)
CA (1) CA1166255A (en)
ZA (1) ZA812698B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU665590B2 (en) * 1991-11-29 1996-01-11 Zenyaku Kogyo Kabushiki Kaisha Heterocyclic compound and cardiotonic containing the same as active ingredient

Also Published As

Publication number Publication date
CA1166255A (en) 1984-04-24
AU6991781A (en) 1981-11-05
BE888567A (en) 1981-10-27
KR830005202A (en) 1983-08-03
JPS572284A (en) 1982-01-07

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