ZA811227B - 2-alkyl-5 hydroxy-1,4-naphtaquinone, method for its manufacture and pharmaceutical compounds - Google Patents

2-alkyl-5 hydroxy-1,4-naphtaquinone, method for its manufacture and pharmaceutical compounds

Info

Publication number
ZA811227B
ZA811227B ZA00811227A ZA811227A ZA811227B ZA 811227 B ZA811227 B ZA 811227B ZA 00811227 A ZA00811227 A ZA 00811227A ZA 811227 A ZA811227 A ZA 811227A ZA 811227 B ZA811227 B ZA 811227B
Authority
ZA
South Africa
Prior art keywords
hydroxy
alkyl
naphtaquinone
manufacture
pharmaceutical compounds
Prior art date
Application number
ZA00811227A
Inventor
G Wurm
Original Assignee
Zyma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyma Gmbh filed Critical Zyma Gmbh
Publication of ZA811227B publication Critical patent/ZA811227B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00Quinones
    • C07C50/26Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • C07C46/02Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • C07C46/02Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C07C46/08Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring with molecular oxygen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)

Abstract

1. 2-Alkyl-5-hydroxy-1,4-naphthoquinones of the general formula I see diagramm : EP0036502,P9,F1 wherein Y denotes the methyl, ethyl, n-propyl, isopropyl or tert.-butyl group.
ZA00811227A 1980-02-27 1981-02-24 2-alkyl-5 hydroxy-1,4-naphtaquinone, method for its manufacture and pharmaceutical compounds ZA811227B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3007367A DE3007367C2 (en) 1980-02-27 1980-02-27 2-alkyl-5-hydroxy-1,4-naphthoquinones, processes for their preparation and pharmaceuticals

Publications (1)

Publication Number Publication Date
ZA811227B true ZA811227B (en) 1982-03-31

Family

ID=6095701

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00811227A ZA811227B (en) 1980-02-27 1981-02-24 2-alkyl-5 hydroxy-1,4-naphtaquinone, method for its manufacture and pharmaceutical compounds

Country Status (6)

Country Link
EP (1) EP0036502B1 (en)
AT (1) ATE5066T1 (en)
DE (2) DE3007367C2 (en)
ES (1) ES8301866A1 (en)
HU (1) HU188282B (en)
ZA (1) ZA811227B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431236A1 (en) * 1984-08-24 1986-02-27 Carnivora-Deutschland GmbH, 7109 Jagsthausen USE OF 1,4-NAPHTHOQUINONE DERIVATIVES IN LOW CONCENTRATIONS FOR IMMUNE STIMULATION
ZA863425B (en) * 1985-05-08 1988-01-27 Du Pont 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US4833164A (en) 1985-05-08 1989-05-23 E. I. Du Pont De Nemours And Company 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2572946A (en) * 1949-11-19 1951-10-30 Du Pont Composition comprising 2-aliphatic-3-hydroxy-1, 4 napthoquinone and method for controlling mites and aphids
US3578686A (en) * 1968-04-26 1971-05-11 Sterling Drug Inc 2-hydroxy - 3 -((3,3,5-trimethylcyclohexyl)-alkyl) - 1,4-naphthoquinones and their preparation

Also Published As

Publication number Publication date
EP0036502B1 (en) 1983-10-19
ES499847A0 (en) 1983-01-01
HU188282B (en) 1986-03-28
EP0036502A1 (en) 1981-09-30
DE3007367C2 (en) 1982-07-08
ES8301866A1 (en) 1983-01-01
DE3007367A1 (en) 1981-09-03
ATE5066T1 (en) 1983-11-15
DE3161204D1 (en) 1983-11-24

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