ZA792935B - Prostaglandin vasodilators and hypotensive agents for administration topically or by injection - Google Patents

Prostaglandin vasodilators and hypotensive agents for administration topically or by injection

Info

Publication number
ZA792935B
ZA792935B ZA792935A ZA792935A ZA792935B ZA 792935 B ZA792935 B ZA 792935B ZA 792935 A ZA792935 A ZA 792935A ZA 792935 A ZA792935 A ZA 792935A ZA 792935 B ZA792935 B ZA 792935B
Authority
ZA
South Africa
Prior art keywords
vasodilators
prostaglandin
injection
hypotensive agents
administration topically
Prior art date
Application number
ZA792935A
Other languages
English (en)
Inventor
J Birnbaum
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ZA792935B publication Critical patent/ZA792935B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA792935A 1978-08-16 1979-06-13 Prostaglandin vasodilators and hypotensive agents for administration topically or by injection ZA792935B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/934,199 US4254145A (en) 1978-08-16 1978-08-16 Topical application of prostaglandin hypotensive agents

Publications (1)

Publication Number Publication Date
ZA792935B true ZA792935B (en) 1980-06-25

Family

ID=25465143

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA792935A ZA792935B (en) 1978-08-16 1979-06-13 Prostaglandin vasodilators and hypotensive agents for administration topically or by injection

Country Status (7)

Country Link
US (1) US4254145A (de)
EP (1) EP0008227B1 (de)
JP (1) JPS5536494A (de)
AU (1) AU530454B2 (de)
CA (1) CA1134270A (de)
DE (1) DE2965284D1 (de)
ZA (1) ZA792935B (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
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US4311707A (en) * 1979-02-12 1982-01-19 American Cyanamid Company Process for topically producing cutaneous vasodilation for the treatment of vasospastic or ischemic conditions
US4564637A (en) * 1981-08-19 1986-01-14 Schachar Ronald A Method for maintaining corneal shape after radial keratotomy
US4599353A (en) * 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
JPS5948409A (ja) * 1982-09-10 1984-03-19 Teikoku Seiyaku Kk 矯正的歯牙移動促進剤
US4450175A (en) * 1982-09-23 1984-05-22 Warshaw Thelma G Method and compositions for treating acne
JPS59128327A (ja) * 1983-01-10 1984-07-24 Teijin Ltd ７−チアプロスタグランジンｅ↓１類を有効成分とする経皮投与用薬剤
US5472687A (en) * 1985-07-18 1995-12-05 Proctor; Peter H. Topical pyridine N-oxides
US5716947A (en) * 1985-07-18 1998-02-10 Proctor; Peter H. Topical doxyl composition and method
US5714482A (en) * 1985-07-18 1998-02-03 Proctor; Peter H. Topical spin labels and method
US5352442A (en) * 1985-07-18 1994-10-04 Proctor Peter H Topical tempo
US5723502A (en) * 1985-07-18 1998-03-03 Proctor; Peter H. Topical spin trap composition and method
US5470876A (en) * 1985-07-18 1995-11-28 Proctor; Peter H. Topical sod for treating hair loss
US5728714A (en) * 1985-07-18 1998-03-17 Proctor; Peter H. Method for treating hair loss using tempo
US6150405A (en) * 1985-07-18 2000-11-21 Proctor; Peter H. Hair loss treatment with ascorbates
US5714510A (en) * 1985-07-18 1998-02-03 Proctor; Peter H. Topical proxyl composition and method
US4707495A (en) * 1985-10-28 1987-11-17 Ortho Pharmaceutical Peptic ulcer treatment method
AU602509B2 (en) * 1986-03-13 1990-10-18 Trustees Of Columbia University In The City Of New York, The Use of A,B and C prostaglandins and derivatives therof to treat ocular hypertension and glaucoma
US5164416A (en) * 1989-02-03 1992-11-17 Lintec Corporation Transdermal therapeutic formulation containing a limonene
ATE164763T1 (de) * 1990-12-10 1998-04-15 Allergan Inc Okulare hypotensive homo-prostaglandinderivate
US5262437A (en) * 1990-12-10 1993-11-16 Allergan, Inc. Homo-prostaglandin derivatives as ocular hypotensives
US5578643A (en) * 1992-05-20 1996-11-26 Loyola University Of Chicago Protective prostaglandins for use in conjunction with chemotherapeutic agents
US5656663A (en) * 1993-02-03 1997-08-12 Teijin Limited External skin treatment agent composition containing isocarbacyclins as active ingredient
AU669783B2 (en) * 1993-02-03 1996-06-20 Teijin Limited Dermatologic preparation composition containing prostacyclinas active ingredient
US5324746A (en) * 1993-02-12 1994-06-28 Mckee Rex N Method of treating damaged mucosal and epithelial tissues with misoprostol
US6007836A (en) * 1993-05-28 1999-12-28 Vericade, Inc. Transdermal vasodilator
US5380760A (en) * 1993-11-19 1995-01-10 Minnesota Mining And Manufacturing Company Transdermal prostaglandin composition
SE9403158D0 (sv) * 1994-09-21 1994-09-21 Pharmacia Ab New use of prostaglandins
US5994399A (en) * 1997-03-27 1999-11-30 Mckee; Rex N. Method of regenerating collagen-containing tissues with misoprostol
AU742787B2 (en) 1997-07-09 2002-01-10 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
US6593369B2 (en) 1997-10-20 2003-07-15 Vivus, Inc. Methods, compositions, and kits for enhancing female sexual desire and responsiveness
WO1999021562A1 (en) 1997-10-28 1999-05-06 Asivi, Llc Treatment of female sexual dysfunction
US20050070516A1 (en) * 1997-10-28 2005-03-31 Vivus Inc. As-needed administration of an androgenic agent to enhance female desire and responsiveness
US5877216A (en) * 1997-10-28 1999-03-02 Vivus, Incorporated Treatment of female sexual dysfunction
WO2000012110A2 (en) * 1998-08-26 2000-03-09 Queen's University At Kingston Use of anti(w)pressor agents for vascular remodeling in genital dysfunction
US6486207B2 (en) 1998-12-10 2002-11-26 Nexmed (Holdings), Inc. Compositions and methods for amelioration of human female sexual dysfunction
US20070191320A1 (en) * 1998-12-10 2007-08-16 Nexmed Holdings, Inc. Methods of treatment for female sexual arousal disorder
US6825234B2 (en) 1998-12-10 2004-11-30 Nexmed (Holdings) , Inc. Compositions and methods for amelioration of human female sexual dysfunction
US7105571B2 (en) * 2000-01-10 2006-09-12 Nexmed Holdings, Inc. Prostaglandin compositions and methods of treatment for male erectile dysfunction
US6693135B2 (en) 2000-01-10 2004-02-17 Nexmed (Holdings) Incorporated Prostaglandin compositions and methods of treatment for male erectile dysfunction
US6323241B1 (en) 2000-01-10 2001-11-27 Nexmed (Holdings) Inc. Prostaglandin compositions and methods of treatment for male erectile dysfunction
JP4288883B2 (ja) * 2000-02-10 2009-07-01 花王株式会社 自律神経調整剤
EP1353727A2 (de) * 2000-12-01 2003-10-22 Novartis AG Kombinationen eines angiotensinrezeptor-hemmers und eines antihypertensiven medikaments oder eines statins, zur behandlung sexueller funktionsstörungen
WO2003057162A2 (en) * 2002-01-04 2003-07-17 Combinatorx, Incorporated Combination for the treatment of immunoinflammatory disorders and proliferative skin diseases
WO2003092617A2 (en) * 2002-05-03 2003-11-13 Combinatorx, Incorporated Combinations for the treatment of inflammatory skin disorders
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US7241746B2 (en) * 2003-08-06 2007-07-10 Regena Therapeutics, Lc Method and composition for treating periodontal disease
KR101161889B1 (ko) * 2003-12-16 2012-07-02 유나이티드 쎄러퓨틱스 코포레이션 허혈성 병변의 치료 및 예방을 위한 트레프로스티닐의 용도
US20090124697A1 (en) 2003-12-16 2009-05-14 United Therapeutics Corporation Inhalation formulations of treprostinil
SE0402029D0 (sv) * 2004-08-17 2004-08-17 Synphora Ab Prostaglandin a derivatieves for the treatment of psoriasis
CA2600331C (en) * 2005-03-04 2014-07-08 Sucampo Ag Use of 11-deoxy-prostaglandin for treating peripheral vascular diseases
US20070254861A1 (en) * 2006-04-28 2007-11-01 Astellas Pharma Inc. Methods for the prevention and/or treatment of peripheral arterial disease
US20120251613A1 (en) * 2011-03-29 2012-10-04 Agila Specialities Pvt. Ltd. Method for treating vitiligo with a prostaglandin analogue
BR112014008190A2 (pt) * 2011-10-05 2017-04-18 Allergan Inc composições para realce da saúde da unha
FR2984167B1 (fr) * 2011-12-16 2014-01-17 Galderma Res & Dev Association d'un agoniste des recepteurs des prostaglandines et d'un agoniste du recepteur mc1r pour le traitement et/ou la prevention de desordres de la pigmentation

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US3551554A (en) * 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
US4094899A (en) * 1972-06-02 1978-06-13 Pfizer Inc. Oxaprostaglandins
FR2235678A1 (en) * 1973-07-02 1975-01-31 Merck & Co Inc Topical antipsoriasis agents - contg. prostaglandin E1 or E2
DE2346706A1 (de) * 1973-09-17 1975-04-03 Hoechst Ag Neue, nicht natuerlich vorkommende analoga von prostansaeuren und verfahren zu ihrer herstellung
US4009282A (en) * 1973-12-17 1977-02-22 The Regents Of The University Of Michigan Treatment of proliferating skin diseases with prostaglandins
US3919302A (en) * 1974-02-28 1975-11-11 American Home Prod 11,15 Dimethyl-11 deoxy PGF{HD 2 {B
US4080506A (en) * 1974-08-14 1978-03-21 The Upjohn Company Phenacyl-type esters of PGA1 and PGA2
US4028396A (en) * 1975-07-02 1977-06-07 American Cyanamid Company 16,16-Spirocycloalkyl prostaglandin derivatives
US4061670A (en) * 1976-07-19 1977-12-06 American Cyanamid Company 15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners
US4103026A (en) * 1976-08-23 1978-07-25 Carlson Lars A Treatment of peripheral vascular disease by non-intraarterial administration of prostaglandin E1
US4085272A (en) * 1977-03-30 1978-04-18 American Cyanamid Company 11-(2-Hydroxyethylthio)prostenoic acid E2 series derivatives
US4154959A (en) * 1977-03-30 1979-05-15 American Cyanamid Company 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives
US4154954A (en) * 1977-03-30 1979-05-15 American Cyanamid Company 11-(2-Hydroxyethylthio) prostenoic acid E series derivatives
CA1148149A (en) * 1977-12-08 1983-06-14 Allan Wissner Prostaglandin activity

Also Published As

Publication number Publication date
US4254145A (en) 1981-03-03
CA1134270A (en) 1982-10-26
EP0008227A1 (de) 1980-02-20
AU4917179A (en) 1980-02-21
EP0008227B1 (de) 1983-04-27
AU530454B2 (en) 1983-07-14
JPS5536494A (en) 1980-03-14
DE2965284D1 (en) 1983-09-01

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