ZA745309B - Adenine derivatives and preparation thereof - Google Patents

Adenine derivatives and preparation thereof

Info

Publication number
ZA745309B
ZA745309B ZA00745309A ZA745309A ZA745309B ZA 745309 B ZA745309 B ZA 745309B ZA 00745309 A ZA00745309 A ZA 00745309A ZA 745309 A ZA745309 A ZA 745309A ZA 745309 B ZA745309 B ZA 745309B
Authority
ZA
South Africa
Prior art keywords
preparation
adenine derivatives
adenine
derivatives
Prior art date
Application number
ZA00745309A
Other languages
English (en)
Inventor
R Jonas
W Mehrhof
K Becker
H Schliep
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA745309B publication Critical patent/ZA745309B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA00745309A 1973-11-07 1974-08-19 Adenine derivatives and preparation thereof ZA745309B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732355536 DE2355536A1 (de) 1973-11-07 1973-11-07 Adeninderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA745309B true ZA745309B (en) 1975-09-24

Family

ID=5897376

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00745309A ZA745309B (en) 1973-11-07 1974-08-19 Adenine derivatives and preparation thereof

Country Status (12)

Country Link
US (1) US3989833A (es)
JP (1) JPS5077395A (es)
BE (1) BE821893A (es)
DD (1) DD114414A5 (es)
DE (1) DE2355536A1 (es)
DK (1) DK133810C (es)
FR (1) FR2249672B1 (es)
GB (1) GB1444690A (es)
IL (1) IL45489A0 (es)
NL (1) NL7414527A (es)
SE (1) SE7413858L (es)
ZA (1) ZA745309B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364922A (en) * 1980-10-14 1982-12-21 University Of Virginia Alumni Patents Foundation Adenosine antagonists in the treatment and diagnosis of A-V node conduction disturbances
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
WO1990009178A1 (en) * 1989-01-31 1990-08-23 Whitby Research, Inc. N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5670501A (en) * 1994-09-01 1997-09-23 Discovery Therapeutics, Inc. N-substituted 9-alkyladenines
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7203984A (es) * 1971-04-10 1972-10-12

Also Published As

Publication number Publication date
IL45489A0 (en) 1974-11-29
US3989833A (en) 1976-11-02
DE2355536A1 (de) 1975-05-22
DD114414A5 (es) 1975-08-05
DK133810C (da) 1976-12-13
DK133810B (da) 1976-07-26
FR2249672A1 (es) 1975-05-30
BE821893A (fr) 1975-05-06
GB1444690A (en) 1976-08-04
FR2249672B1 (es) 1977-07-08
DK580074A (es) 1975-07-07
SE7413858L (es) 1975-05-09
NL7414527A (nl) 1975-05-12
JPS5077395A (es) 1975-06-24
AU7502574A (en) 1976-05-06

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