ZA734811B - 1-(3-(5,6,7,8-tetrahydronapht-1-yloxy)-propyl)-piperazine derivatives - Google Patents

1-(3-(5,6,7,8-tetrahydronapht-1-yloxy)-propyl)-piperazine derivatives

Info

Publication number
ZA734811B
ZA734811B ZA734811A ZA734811A ZA734811B ZA 734811 B ZA734811 B ZA 734811B ZA 734811 A ZA734811 A ZA 734811A ZA 734811 A ZA734811 A ZA 734811A ZA 734811 B ZA734811 B ZA 734811B
Authority
ZA
South Africa
Prior art keywords
tetrahydronapht
yloxy
propyl
piperazine derivatives
piperazine
Prior art date
Application number
ZA734811A
Other languages
English (en)
Inventor
E Witte
G Sponer
K Dietmann
K Stach
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA734811B publication Critical patent/ZA734811B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA734811A 1972-07-20 1973-07-16 1-(3-(5,6,7,8-tetrahydronapht-1-yloxy)-propyl)-piperazine derivatives ZA734811B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2235597A DE2235597A1 (de) 1972-07-20 1972-07-20 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA734811B true ZA734811B (en) 1974-07-31

Family

ID=5851155

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA734811A ZA734811B (en) 1972-07-20 1973-07-16 1-(3-(5,6,7,8-tetrahydronapht-1-yloxy)-propyl)-piperazine derivatives

Country Status (14)

Country Link
US (1) US3947446A (et)
JP (1) JPS5331158B2 (et)
AR (1) AR196775A1 (et)
AT (1) AT330188B (et)
CA (1) CA1003836A (et)
CH (2) CH583722A5 (et)
DD (1) DD106842A5 (et)
DE (1) DE2235597A1 (et)
ES (1) ES416929A1 (et)
FR (1) FR2193598B1 (et)
GB (1) GB1376588A (et)
HU (1) HU165887B (et)
NL (1) NL149168B (et)
ZA (1) ZA734811B (et)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL175059C (nl) * 1974-02-23 Boehringer Mannheim Gmbh Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.
DE2658762A1 (de) * 1976-12-24 1978-06-29 Hoechst Ag Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB1583372A (en) * 1977-04-04 1981-01-28 Degussa 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl piperazine derivatives
US4101723A (en) * 1977-04-05 1978-07-18 E. R. Squibb & Sons, Inc. Substituted piperazinopropanols
US4259327A (en) * 1979-04-02 1981-03-31 Merck & Co., Inc. Substituted aminoalkoxypyridines, compositions and use thereof
US4255426A (en) * 1979-07-09 1981-03-10 Pfizer Inc. 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines
DE3918542A1 (de) * 1989-06-07 1990-12-13 Boehringer Mannheim Gmbh Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IT1255178B (it) * 1992-06-26 1995-10-20 Pierrel Spa N(eter0)-aril-n(etero)-tetralinalchil piperazine aventi attivita' serotoninergica,dopaminergica e adrenergica
WO1999058527A2 (en) * 1998-05-14 1999-11-18 EGIS Gyógyszergyár Rt. Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
AU2002333464A1 (en) * 2001-08-31 2003-03-18 Bayer Chemicals Ag Method for producing 4-amino-1-naphthol ethers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1317034A (en) * 1970-11-06 1973-05-16 Pfizer Ltd 1-2-hydroxy-3-phenoxy- or -phenylthiopropyl-piperazine derivatives

Also Published As

Publication number Publication date
JPS5331158B2 (et) 1978-08-31
CA1003836A (en) 1977-01-18
JPS4943990A (et) 1974-04-25
NL7310041A (et) 1974-01-22
ATA636673A (de) 1975-09-15
FR2193598A1 (et) 1974-02-22
FR2193598B1 (et) 1977-07-15
AT330188B (de) 1976-06-25
NL149168B (nl) 1976-04-15
CH583721A5 (et) 1977-01-14
DD106842A5 (et) 1974-07-05
AR196775A1 (es) 1974-02-19
HU165887B (et) 1974-12-28
ES416929A1 (es) 1976-03-01
DE2235597A1 (de) 1974-01-31
US3947446A (en) 1976-03-30
GB1376588A (en) 1974-12-04
CH583722A5 (et) 1977-01-14

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