ZA727971B - Steroids having anaesthetic activity and pharmaceutical compositions based thereon - Google Patents

Steroids having anaesthetic activity and pharmaceutical compositions based thereon

Info

Publication number
ZA727971B
ZA727971B ZA727971A ZA727971A ZA727971B ZA 727971 B ZA727971 B ZA 727971B ZA 727971 A ZA727971 A ZA 727971A ZA 727971 A ZA727971 A ZA 727971A ZA 727971 B ZA727971 B ZA 727971B
Authority
ZA
South Africa
Prior art keywords
steroids
pharmaceutical compositions
compositions based
anaesthetic activity
anaesthetic
Prior art date
Application number
ZA727971A
Other languages
English (en)
Inventor
G Phillipps
L Stephenson
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of ZA727971B publication Critical patent/ZA727971B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
ZA727971A 1971-11-11 1972-11-10 Steroids having anaesthetic activity and pharmaceutical compositions based thereon ZA727971B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5246671A GB1409240A (en) 1971-11-11 1971-11-11 Anaesthetic steroid of the 5alpha-pregnane series

Publications (1)

Publication Number Publication Date
ZA727971B true ZA727971B (en) 1973-09-26

Family

ID=10464023

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA727971A ZA727971B (en) 1971-11-11 1972-11-10 Steroids having anaesthetic activity and pharmaceutical compositions based thereon

Country Status (16)

Country Link
US (1) US3822297A (enExample)
JP (1) JPS4861465A (enExample)
AU (1) AU476623B2 (enExample)
BE (1) BE791196A (enExample)
CA (1) CA992068A (enExample)
DE (1) DE2255153A1 (enExample)
DK (1) DK131296B (enExample)
ES (1) ES408509A1 (enExample)
FR (1) FR2159447B1 (enExample)
GB (1) GB1409240A (enExample)
IE (1) IE37076B1 (enExample)
IL (1) IL40790A (enExample)
NL (1) NL7215225A (enExample)
PH (1) PH9928A (enExample)
SE (1) SE390025B (enExample)
ZA (1) ZA727971B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952031A (en) * 1970-11-12 1976-04-20 Glaxo Laboratories Limited Anaesthetic composition containing a steroid of the 5α-pregnane series and method of using same
DE2438020A1 (de) * 1974-08-05 1976-02-26 Schering Ag 18-methyl-19-nor-20-keto-pregnane und verfahren zu ihrer herstellung
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
AUPN498095A0 (en) * 1995-08-23 1995-09-14 Goodchild, Colin Stanley Compounds and compositions
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1281205A (fr) * 1956-12-21 1962-01-12 Organon Nv Procédé d'obtention de composés de la série du prégnane

Also Published As

Publication number Publication date
DK131296C (enExample) 1975-11-17
IE37076B1 (en) 1977-04-27
BE791196A (fr) 1973-05-10
CA992068A (en) 1976-06-29
AU476623B2 (en) 1976-09-30
JPS4861465A (enExample) 1973-08-28
DE2255153A1 (de) 1973-05-24
IL40790A (en) 1975-05-22
US3822297A (en) 1974-07-02
DK131296B (da) 1975-06-23
IL40790A0 (en) 1973-01-30
FR2159447B1 (enExample) 1976-08-20
IE37076L (en) 1973-05-11
FR2159447A1 (enExample) 1973-06-22
AU4875472A (en) 1974-05-16
GB1409240A (en) 1975-10-08
ES408509A1 (es) 1976-05-01
SE390025B (sv) 1976-11-29
PH9928A (en) 1976-06-14
NL7215225A (enExample) 1973-05-15

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