ZA711588B - Process for the manufacture of quinoline derivatives - Google Patents

Process for the manufacture of quinoline derivatives

Info

Publication number
ZA711588B
ZA711588B ZA711588A ZA711588A ZA711588B ZA 711588 B ZA711588 B ZA 711588B ZA 711588 A ZA711588 A ZA 711588A ZA 711588 A ZA711588 A ZA 711588A ZA 711588 B ZA711588 B ZA 711588B
Authority
ZA
South Africa
Prior art keywords
manufacture
quinoline derivatives
quinoline
derivatives
Prior art date
Application number
ZA711588A
Other languages
English (en)
Inventor
G Grethe
M Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA711588B publication Critical patent/ZA711588B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA711588A 1970-03-16 1971-03-11 Process for the manufacture of quinoline derivatives ZA711588B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2003470A 1970-03-16 1970-03-16

Publications (1)

Publication Number Publication Date
ZA711588B true ZA711588B (en) 1971-12-29

Family

ID=21796376

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA711588A ZA711588B (en) 1970-03-16 1971-03-11 Process for the manufacture of quinoline derivatives

Country Status (14)

Country Link
AT (1) AT341116B (fr)
BE (1) BE764252A (fr)
CA (1) CA940530A (fr)
CH (2) CH590275A5 (fr)
DE (1) DE2111938A1 (fr)
DK (1) DK137189B (fr)
FR (1) FR2100618B1 (fr)
GB (1) GB1313963A (fr)
IE (1) IE35284B1 (fr)
IL (1) IL36400A (fr)
NL (1) NL7103506A (fr)
PH (1) PH9976A (fr)
SE (1) SE395699B (fr)
ZA (1) ZA711588B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605916A5 (fr) * 1973-12-07 1978-10-13 Hoffmann La Roche
FR2381044A1 (fr) * 1977-02-17 1978-09-15 Hoffmann La Roche Procede pour la preparation de mefloquine
EP0000302B1 (fr) * 1977-06-15 1980-10-01 Devinter S.A. Nouveau procédé de préparation de la quinidine.
EP1212322A2 (fr) 1999-08-27 2002-06-12 Ligand Pharmaceuticals Incorporated Composes de 6-trifluoromethyl-9-pyrido[3,2-g]quinoline 8-substitues utilises comme modulateurs de recepteurs androgenes
WO2001016139A1 (fr) * 1999-08-27 2001-03-08 Ligand Pharmaceuticals Incorporated Composes de modulation du recepteur androgene et procedes d'utilisation
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
AU7586600A (en) 1999-09-14 2001-04-17 Ligand Pharmaceuticals Incorporated Rxr modulators with improved pharmacologic profile

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH533123A (de) * 1968-07-02 1973-01-31 Hoffmann La Roche Verfahren zur Herstellung von Chinolinderivaten

Also Published As

Publication number Publication date
FR2100618B1 (fr) 1974-08-23
DK137189B (da) 1978-01-30
IL36400A0 (en) 1971-05-26
DE2111938A1 (de) 1971-10-07
CH590275A5 (fr) 1977-07-29
IE35284L (en) 1971-09-16
CH590274A5 (fr) 1977-07-29
DK137189C (fr) 1978-07-03
IE35284B1 (en) 1976-01-07
PH9976A (en) 1976-06-16
BE764252A (fr) 1971-09-15
SE395699B (sv) 1977-08-22
CA940530A (en) 1974-01-22
AT341116B (de) 1978-01-25
IL36400A (en) 1973-07-30
GB1313963A (en) 1973-04-18
ATA220971A (de) 1977-05-15
NL7103506A (fr) 1971-09-20
FR2100618A1 (fr) 1972-03-24

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