ZA202406418B - Chromanol compounds for treatment or prophylaxis of ageing-associated disorders - Google Patents
Chromanol compounds for treatment or prophylaxis of ageing-associated disordersInfo
- Publication number
- ZA202406418B ZA202406418B ZA2024/06418A ZA202406418A ZA202406418B ZA 202406418 B ZA202406418 B ZA 202406418B ZA 2024/06418 A ZA2024/06418 A ZA 2024/06418A ZA 202406418 A ZA202406418 A ZA 202406418A ZA 202406418 B ZA202406418 B ZA 202406418B
- Authority
- ZA
- South Africa
- Prior art keywords
- ageing
- prophylaxis
- treatment
- chromanol
- sul
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2031091A NL2031091B1 (en) | 2022-02-28 | 2022-02-28 | Chromanol compounds for treatment or prophylaxis of ageing and ageing-associated disorders |
| PCT/NL2023/050095 WO2023163596A1 (en) | 2022-02-28 | 2023-02-28 | Chromanol compounds for treatment or prophylaxis of ageing-associated disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA202406418B true ZA202406418B (en) | 2025-11-26 |
Family
ID=83271289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2024/06418A ZA202406418B (en) | 2022-02-28 | 2024-08-21 | Chromanol compounds for treatment or prophylaxis of ageing-associated disorders |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250177384A1 (https=) |
| EP (1) | EP4486317A1 (https=) |
| JP (1) | JP2025506844A (https=) |
| CN (1) | CN118742301A (https=) |
| AU (1) | AU2023225518A1 (https=) |
| CA (1) | CA3252944A1 (https=) |
| CL (1) | CL2024002555A1 (https=) |
| NL (1) | NL2031091B1 (https=) |
| WO (1) | WO2023163596A1 (https=) |
| ZA (1) | ZA202406418B (https=) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006105806A1 (en) | 2005-04-07 | 2006-10-12 | Miso Sabovic | Delaying the ageing process and disorders caused by ageing |
| EP2680838A1 (en) | 2011-02-28 | 2014-01-08 | Farmicom Pharmaceutical Company D.O.O. | TREATMENT OF ARTERIAL AGEING BY COMBINATION OF RAAS INHIBITOR AND HMG-CoA REDUCTASE INHIBITOR |
| KR102137450B1 (ko) | 2012-07-12 | 2020-07-27 | 콘드리온 아이피 비.브이. | 미토콘드리아 질환을 치료하기 위한 크로마닐 유도체 |
| NL2010010C2 (en) | 2012-12-19 | 2014-06-23 | Sulfateq B V | Compounds for protection of cells. |
| WO2015148522A1 (en) | 2014-03-24 | 2015-10-01 | Seals Douglas R | Methods for treatment of vascular endothelial dysfunction using nicotinamide mononucleotide |
| NL2013012B1 (en) * | 2014-06-17 | 2016-07-05 | Sulfateq Bv | Compounds for the treatment of chronic obstructive airway diseases. |
| US10815211B2 (en) | 2015-10-08 | 2020-10-27 | Khondrion Ip B.V. | Compounds for treating mitochondrial disease |
| ES2959243T3 (es) * | 2017-04-05 | 2024-02-22 | Khondrion Ip B V | Nuevo tratamiento de enfermedades mitocondriales |
| EP3672593B1 (en) * | 2017-08-25 | 2024-12-18 | Sulfateq B.V. | Medicaments for the treatment of vasoconstriction related diseases or disorders |
| WO2019038360A1 (en) * | 2017-08-25 | 2019-02-28 | Sulfateq B.V. | 6-CHROMANOL DERIVATIVES FOR USE AS A MEDICINAL PRODUCT |
| NL2024431B1 (en) * | 2019-12-11 | 2021-09-07 | Sulfateq Bv | Compounds for treatment of alzheimer’s disease |
| NL2026511B1 (en) * | 2020-09-21 | 2022-05-24 | Sulfateq Bv | Compounds for treatment of heart failure |
-
2022
- 2022-02-28 NL NL2031091A patent/NL2031091B1/en active
-
2023
- 2023-02-28 AU AU2023225518A patent/AU2023225518A1/en active Pending
- 2023-02-28 WO PCT/NL2023/050095 patent/WO2023163596A1/en not_active Ceased
- 2023-02-28 JP JP2024550618A patent/JP2025506844A/ja active Pending
- 2023-02-28 CN CN202380023421.3A patent/CN118742301A/zh active Pending
- 2023-02-28 US US18/842,075 patent/US20250177384A1/en active Pending
- 2023-02-28 CA CA3252944A patent/CA3252944A1/en active Pending
- 2023-02-28 EP EP23710478.1A patent/EP4486317A1/en active Pending
-
2024
- 2024-08-21 ZA ZA2024/06418A patent/ZA202406418B/en unknown
- 2024-08-27 CL CL2024002555A patent/CL2024002555A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20250177384A1 (en) | 2025-06-05 |
| CN118742301A (zh) | 2024-10-01 |
| AU2023225518A1 (en) | 2024-09-12 |
| EP4486317A1 (en) | 2025-01-08 |
| NL2031091B1 (en) | 2023-09-07 |
| CL2024002555A1 (es) | 2025-01-10 |
| JP2025506844A (ja) | 2025-03-13 |
| WO2023163596A1 (en) | 2023-08-31 |
| CA3252944A1 (en) | 2023-08-31 |
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