ZA202306305B - Pharmaceutical compounds - Google Patents
Pharmaceutical compoundsInfo
- Publication number
- ZA202306305B ZA202306305B ZA2023/06305A ZA202306305A ZA202306305B ZA 202306305 B ZA202306305 B ZA 202306305B ZA 2023/06305 A ZA2023/06305 A ZA 2023/06305A ZA 202306305 A ZA202306305 A ZA 202306305A ZA 202306305 B ZA202306305 B ZA 202306305B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- pharmaceutical compounds
- muscarinic
- agonists
- receptors
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 102000017924 CHRM4 Human genes 0.000 abstract 2
- 102000007207 Muscarinic M1 Receptor Human genes 0.000 abstract 2
- 108010008406 Muscarinic M1 Receptor Proteins 0.000 abstract 2
- 101100107916 Xenopus laevis chrm4 gene Proteins 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention relates to compounds that are agonists of the muscarinic M1 and M4 receptor and which are useful in the treatment of diseases mediated by the muscarinic M1 and/or M4 receptors. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula (1): and salts thereof.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH55002019 | 2019-04-23 | ||
| GBGB2020191.9A GB202020191D0 (en) | 2020-12-18 | 2020-12-18 | Pharmaceutical compounds |
| PCT/GB2021/053372 WO2022129951A1 (en) | 2020-12-18 | 2021-12-20 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA202306305B true ZA202306305B (en) | 2024-03-27 |
Family
ID=90732524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2023/06305A ZA202306305B (en) | 2019-04-23 | 2023-06-15 | Pharmaceutical compounds |
Country Status (1)
| Country | Link |
|---|---|
| ZA (1) | ZA202306305B (en) |
-
2023
- 2023-06-15 ZA ZA2023/06305A patent/ZA202306305B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2020014156A (en) | Oxadiazoles as agonists of the muscarinic m1 and/or m4 receptor. | |
| PH12021550166A1 (en) | Nlrp3 inflammasome inhibitors | |
| MX2018001564A (en) | Muscarinic agonists. | |
| CR20230256A (en) | Pharmaceutical compounds | |
| PH12016501570A1 (en) | Bicyclic aza compounds as muscarinic m1 receptor and/or m4 receptor agonists | |
| MX2020010674A (en) | Muscarinic receptor agonists. | |
| SA518392101B1 (en) | Benzimidazole Derivatives as Modulators of ROR-GAMMA | |
| IN2014KN01075A (en) | ||
| JOP20220069A1 (en) | Brd9 bifunctional degraders and their methods of use | |
| MX2020011405A (en) | Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (rorï) and pharmaceutical uses thereof. | |
| MY147677A (en) | Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases | |
| MX2019012847A (en) | C5-anilinoquinazoline compounds and their use in treating cancer. | |
| MX2023000677A (en) | Estrogen receptor-modulating compounds. | |
| NZ734400A (en) | Amide compounds as 5-ht4 receptor agonists | |
| NZ737892A (en) | Muscarinic m1 receptor positive allosteric modulators | |
| NZ740587A (en) | Fluoroindole derivatives as muscarinic m1 receptor positive allosteric modulators | |
| MX2021008510A (en) | Thiazolopyridine derivatives as adenosine receptor antagonists. | |
| ATE552257T1 (en) | POSITIVE ALLOSTERIC QUINOLICIDINONE M1 RECEPTOR MODULATORS | |
| MX2021003508A (en) | 5-azaindazole derivatives as adenosine receptor antagonists. | |
| PH12021550143A1 (en) | Pyridopyrimidines as histamine h4-receptor inhibitors | |
| PH12020500542A1 (en) | Dopamine-b-hydroxylase inhibitors | |
| MX2021003901A (en) | 5-azaindazole derivatives as adenosine receptor antagonists. | |
| ZA202306305B (en) | Pharmaceutical compounds | |
| UY39681A (en) | 1,3-Substituted Cyclobutyl Derivatives and Their Uses | |
| WO2024028458A3 (en) | Crystalline forms and salts of a muscarinic receptor agonist |