ZA202100861B - Method for preparing recombinant human coagulation factor viii - Google Patents

Method for preparing recombinant human coagulation factor viii

Info

Publication number
ZA202100861B
ZA202100861B ZA2021/00861A ZA202100861A ZA202100861B ZA 202100861 B ZA202100861 B ZA 202100861B ZA 2021/00861 A ZA2021/00861 A ZA 2021/00861A ZA 202100861 A ZA202100861 A ZA 202100861A ZA 202100861 B ZA202100861 B ZA 202100861B
Authority
ZA
South Africa
Prior art keywords
recombinant human
factor viii
coagulation factor
human coagulation
preparing recombinant
Prior art date
Application number
ZA2021/00861A
Inventor
Hu Weiwei
Shang Zhanqiang
Du Min
Lu Jiansheng
Su Xiande
Zhang Zhewen
Xie Yilong
Fei Ruxiang
Wu Ding
Original Assignee
Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group
Chia Tai Tianqing Pharmaceutical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group, Chia Tai Tianqing Pharmaceutical Group Co Ltd filed Critical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group
Publication of ZA202100861B publication Critical patent/ZA202100861B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA2021/00861A 2018-07-26 2021-02-08 Method for preparing recombinant human coagulation factor viii ZA202100861B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201810859618 2018-07-26
PCT/CN2019/097984 WO2020020364A1 (en) 2018-07-26 2019-07-26 Method for preparing recombinant human coagulation factor viii

Publications (1)

Publication Number Publication Date
ZA202100861B true ZA202100861B (en) 2022-05-25

Family

ID=69181337

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2021/00861A ZA202100861B (en) 2018-07-26 2021-02-08 Method for preparing recombinant human coagulation factor viii

Country Status (4)

Country Link
CN (1) CN112469821B (en)
PH (1) PH12021550195A1 (en)
WO (1) WO2020020364A1 (en)
ZA (1) ZA202100861B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115819608A (en) * 2022-10-08 2023-03-21 盛禾(中国)生物制药有限公司 Method for purifying fusion protein

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5471501A (en) * 2000-03-22 2001-10-03 Octagene Gmbh Production of recombinant blood clotting factors in human cell lines
CN102311495A (en) * 2010-06-30 2012-01-11 上海同科生物科技有限公司 Novel recombinant human blood coagulation factor VIII and production method thereof
EP3626737B1 (en) * 2011-05-13 2023-11-29 Octapharma AG A method of increasing the productivity of eucaryotic cells in the production of recombinant fviii
CN102321668A (en) * 2011-07-06 2012-01-18 中国人民解放军军事医学科学院野战输血研究所 A kind of method of express recombinant human blood coagulation factors VII and dedicated carrier thereof
CN103215308B (en) * 2013-02-01 2015-12-23 中国科学院苏州生物医学工程技术研究所 Express the integrated plasmid of recombinant human FVIII, cell strain and construction process thereof and application
CN103555759A (en) * 2013-07-05 2014-02-05 兰诺生物技术无锡有限公司 Method for preparing coagulation factor VIII by using rabbit mammary gland bioreactor
CN107287265B (en) * 2016-03-31 2018-09-14 正大天晴药业集团南京顺欣制药有限公司 A kind of method of Prepare restructuring human blood coagulation factors VIII

Also Published As

Publication number Publication date
PH12021550195A1 (en) 2022-02-21
CN112469821B (en) 2021-12-14
WO2020020364A1 (en) 2020-01-30
CN112469821A (en) 2021-03-09

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